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Application of Serum Ferritin Combined with Blood Routine Testing in the Screening of Obstetrics and Gynecology Diseases

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Advances in Reproductive Sciences 2021年第2期9卷 118-128页

作者： Yueliao Ma Zhiyong qin Chundong Qiu xiaohua Huang Laboratory Department of Maternal and Child Health Hospital Hechi China Inspection Department of Guiping People’s Hospital Guigang China First People’s Hospital of Yulin Yulin China Department of Traditional Chinese Medicine of Yunyang County Chongqing China

Objective: To understand the application of serum ferritin combined with blood routine testing in the screening of obstetrics and gynecology diseases in this region. Methods: From January 1, 2017, to October 28, 2020, all obstetric pregnant women, inpatient maternal, gynecological outpatient, and gynecological inpatients in our hospital’s outpatient and inpatient clinics were collected for serum ferritin determination and blood routine related index detection and analysis Changes in results. The application value of serum special protein in gynecological and obstetrical disease screening was put forward. Results: A total of 15,656 cases of obstetrics and gynecology patients were collected, of which 15,300 were pregnant women. Comparing maternity checkups with hospitalized puerpera, the difference of all indexes except RBC was statistically significant (P 0.05). Comparison of hospitalized puerpera and gynecological hospitalization, the difference of other indexes except for MCV, MCH was statistically significant (P 0.05). Conclusion: During the maternity check-up period, the ferritin consump

关键词： Ferritin Pregnant Women Obstetrics Gynecology Disease Screening

Photooligomerization Determines Photosensitivity and Photoreactivity of Plant Cryptochromes

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Molecular Plant 2020年第3期13卷 398-413页

作者： qing Liu Tiantian Su Wenjin He Huibo Ren Siyuan Liu Yadi Chen Lin Gao xiaohua Hu Haoyue Lu Shijiang Cao Ying Huang Xu Wang qin Wang Chentao Lin Basic Forestry and Proteomics Research Center UCLA-FAFU Joint Research Center on Plant ProteomicsCollege of Life SciencesFujian Agriculture and Forestry UniversityFuzhou 350002China Department of Molecular Cell&Developmental BiologyUniversity of CaliforniaLos AngelesCA 90095USA College of Life Sciences Fujian Normal UniversityFuzhou 350108China College of Forestry Fujian Agriculture and Forestry UniversityFuzhou 350002China These authors contributed equally to this article.

Plant and non-plant species possess cryptochrome(CRY)photoreceptors to mediate blue light regulation of development or the circadian *** blue light-dependent homooligomerization of Arabidopsis CRY2 is a known early photoreaction necessary for its functions,but the photobiochemistry and function of light-dependent homooligomerization and heterooligomerization of cryptochromes,collectively referred to as CRY photooligomerization,have not been well ***,we show that photooligomerization is an evolutionarily conserved photoreaction characteristic of CRY photoreceptors in plants and some non-plant *** analyses of the kinetics of the forward and reverse reactions of photooligomerization of Arabidopsis CRY1 and CRY2 provide a previously unrecognized mechanism underlying the different photosensitivity and photoreactivity of these two closely related *** found that photooligomerization is necessary but not sufficient for the functions of CRY2,implying that CRY photooligomerization is presumably accompanied by additional function-empowering conformational *** further demonstrated that the CRY2-CRY1 heterooligomerization plays roles in regulating functions of Arabidopsis CRYs in *** together,these results suggest that photooligomerization is an evolutionarily conserved mechanism determining the photosensitivity and photoreactivity of plant CRYs.

关键词： light signaling photomorphogenesis cryptochrome,oligomerization

Lnc-RP5 Regulates the mi R-129-5p/Notch1/PFV Internal Promoter Axis to Promote the Expression of the Prototype Foamy Virus Transactivator Tas

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Virologica Sinica 2020年第1期35卷 73-82页

作者： Shanshan Xu Liujun Chen Yinglian Tang Peipei Yuan Jun Yan Yingcheng Zheng Li Huang Zhi Li Yan Sun Song Han Jun Yin qin Pan Biwen Peng xiaohua He Wanhong Liu Department of Allergy Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Immunology and Hubei Province Key Laboratory of Allergy and Immunology School of Basic Medical SciencesWuhan UniversityWuhan 430071China Hubei Provincial Key Laboratory of Developmentally Originated Disease Wuhan 430071China College of Life Sciences Shanxi Normal UniversityXi’an 710062China Centre for Medical Research Wuhan UniversityWuhan 430071China

Prototype foamy virus(PFV)is a unique retrovirus that infects animals and humans and does not cause clinical *** noncoding RNAs(lncRNAs)are believed to exert multiple regulatory functions during viral ***,we utilized RNA sequencing(RNA-seq)to characterize and identify the lncRNA lnc-RP5-1086 D14.3.1-1:1(lnc-RP5),which is markedly decreased in PFV-infected ***,little is known about the function of lnc-RP5 during PFV *** this study,we identified lnc-RP5 as a regulator of the PFV transcriptional transactivator(Tas).Lnc-RP5 enhanced the activity of the PFV internal promoter(IP).The expression of PFV Tas was found to be promoted by ***,mi R-129-5 p was found to be involved in the lnc-RP5-mediated promotion of PFV IP activity,while the Notch1 protein suppressed the activity of PFV IP and the expression of *** results demonstrate that lnc-RP5 promotes the expression of PFV Tas through the miR-129-5 p/Notch1/PFV IP *** work provides evidence that host lnc RNAs can manipulate PFV replication by employing mi RNAs and proteins during an early viral infection.

关键词： Prototype foamy virus(PFV) lnc-RP5 Transactivator(Tas) Internal promoter miR-129-5p

Extraction Process and Content Determination of Total Flavonoids in Ginkgo( Ginkgo biloba L. ) Leaves

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Agricultural Biotechnology 2019年第1期8卷 171-175页

作者： Dengfeng ZOU Hua ZHU Binghua qin xiaohua WANG Guilin Medical University

[Objectives]This study was conducted to study the extraction process and the content determination of flavonoids in ginkgo( Ginkgo biloba L.) leaves.[Methods]Ethanol extraction and methanol extraction of total flavonoids in ginkgo leaves were studied,and the optimal extraction conditions for flavonoids were determined by orthogonal test; and with quercetin as reference substance,total flavonoid content in ginkgo leaves was determined by UV spectrophotometry.[Results]The optimal extraction process was 4 h of Soxhlet extraction with methanol; and the total flavonoid contents had a good linear relation in the range of 0. 006 5-0. 039 mg/ml( R^2= 0. 999 9),the average content was stabilized at 1. 135%,and the average recovery of the method was 102. 0%. [Conclusions]This study selected the optimal extraction process for total flavonoids in ginkgo leaves. The test method is simple with high accuracy and precision,and is suitable for the extraction and determination of total flavonoids in ginkgo leaves.

关键词： Ginkgo biloba L. Total flavonoids Extraction process Content determination

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基于增量理论的板材轴对称成形直接积分解法

中国机械工程 2019年第21期30卷 2622-2628页

作者：秦泗吉孔晓华杨莉燕山大学先进成形技术与科学教育部重点实验室

对一般轴对称曲面零件成形,在平面应力假设和增量理论等条件下,以初始构形为参考构形,采用参数分析方法,得到了等效应变增量的微分方程.由于该微分方程包含了等效应变增量和等效应变增量的一阶导数项,一般情况下,等效应变增量的一阶导... 详细信息

对一般轴对称曲面零件成形,在平面应力假设和增量理论等条件下,以初始构形为参考构形,采用参数分析方法,得到了等效应变增量的微分方程.由于该微分方程包含了等效应变增量和等效应变增量的一阶导数项,一般情况下,等效应变增量的一阶导数以隐函数的形式存在,难以采用理论方法进行求解,因此,将等效应变增量的一阶导数表示成其自身、等效应变增量以及参变量的函数,根据泰勒级数展开式和积分的定义给出了逐步积分解法,可用于求解轴对称胀形、翻边、拉深等板材成形问题.以圆筒形件和圆锥形件的拉深成形为例,采用增量理论,将总变形分成若干个增量步,逐步加载,跟踪变形质点,累加应变,求解得到了法兰区和凹模圆角区等的应变分布.对分别采用比例加载条件、增量理论计算得到的结果与实验值进行了比较,结果表明,采用增量理论得到的结果更接近实验值.

关键词：板材成形增量理论比例加载平面应力初始构形直接积分解法

Consecutive Monitoring of Interleukin-6 Is Needed for COVID-19 Patients

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Virologica Sinica 2021年第5期36卷 1093-1096页

作者： xiaohua Chen Juan Zhou Chen Chen Baidong Hou Ashaq Ali Feng Li Zhaolin Hua Yingtao Wu qin Yang Min Chen Rong Zhang Qianchuan Huang Jinya Ding Xian-En Zhang Dong Men Department of Laboratory Medicine General Hospital of Central Theater CommandPLAWuhan 430070China State Key Laboratory of Virology Wuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhan 430071China National Laboratory of Biomacromolecules CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China Department of Laboratory Medicine General Hospital of Southern Theater CommandPLAGuangzhou 510000China State Key Laboratory of Virology School of Basic Medical SciencesWuhan UniversityWuhan 430071China Hubei Provincial Key Laboratory of Allergy and Immunology Wuhan 430071China University of Chinese Academy of Sciences Beijing 100039China

Dear Editor,The world is facing an immense challenge in the fight against coronavirus disease 2019(COVID-19),which is caused by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)(Gorbalenya et al.2020).To date,tens of millions of people worldwide have been infected with SARS-Co V-2,and more than a million have died,and the situation continues.

关键词： Interleukin al. acute

Three-quark potential at finite temperature and chemical potential

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Chinese Physics C 2023年第1期47卷 75-82页

作者：江佳杰肖亚朝秦佳佳李小华陈勋 School of Nuclear Science and Technology University of South ChinaHengyang 421001China

Using gauge/gravity duality,we study the potential energy and the melting of triply heavy baryon at finite temperature and chemical potential in this ***,we calculate the three-quark potential and compare the results with quark-antiquark *** the increase of temperature and chemical potential,the potential energy will decrease at large *** is found that the three-quark potential will have an endpoint at high temperature and/or large chemical potential,which means triply heavy baryons will melt at enough high temperature and/or large chemical *** also discuss screening distance which can be extracted from the three-quark *** last,we draw the melting diagram of triply heavy baryons in the T-μplane.

关键词： triply heavy baryons holographic QCD potential energy

基于在线评论的制造商产品再制造与价格策略研究

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系统科学与数学 2022年第8期42卷 2040-2061页

作者：朱琴韩小花上海大学悉尼工商学院上海201899 广东外语外贸大学商学院广州510420

文章考虑在线评论,研究制造商的产品再制造策略与价格策略.为此,考虑一个制造商在第一阶段销售新产品,消费者使用产品后发布产品评论信息;制造商根据产品评论确定第二阶段是否销售新产品以及是否销售再制造产品,并确定相应的价格策略.... 详细信息

文章考虑在线评论,研究制造商的产品再制造策略与价格策略.为此,考虑一个制造商在第一阶段销售新产品,消费者使用产品后发布产品评论信息;制造商根据产品评论确定第二阶段是否销售新产品以及是否销售再制造产品,并确定相应的价格策略.研究发现:1)无论是否考虑在线评论,制造商的再制造策略均与新产品生产成本有关;当生产成本适中时,在线评论将促使制造商放弃销售新产品,只销售再制造产品.2)在线评论的存在会提高制造商利润,但对其并不总是有利的.当新产品生产成本较高时,不考虑在线评论时制造商的利润反而更高.3)当再制造产品对新产品具有增值效应时,即使新产品生产成本较高,制造商仍然会销售新产品,并且能从增值效应中获利.

关键词：在线评论再制造价格策略博弈论

Effect of Carbides and γ/γ' Eutectic on Crack Initiation and Propagation in Ni-based Superalloy

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Research and Application of Materials Science 2020年第2期2卷 33-42页

作者： Junwei qin xiaohua CHEN Kaixuan CHEN Xinghai YANG Weiyang XIE Yanlin WANG Zidong WANG School of Science and Engineering University of Science and Technology BeijingBeijingChina State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijingChina

The Ni-based Udemit720Li superalloy tends to form largeγ/γ'eutectic on grain boundaries(GBs)during solidification due to the addition of excessive Al and Ti elements,which provides convenience to study the effect of carbide andγ/γ'eutectic on crack initiation and propagation during tensile *** this paper,Udemit720Li superalloy samples were prepared by induction melting casting method,arc melting and suction casting *** microstructure,tensile properties and mechanism of crack initiation and propagation in Ni-based superalloy fabricated by two methods are *** results exhibitγ/γ'eutectic accelerates the stress concentration at GB and thus leads to premature fracture *** samples with grain-boundary eutectic have higher strain hardening rate,but their cumulative and local misorientations are *** samples without eutectic at GB,the primary crack initiates at grain-boundary carbide along GB and extends along GB or into grain matrix,and exhibits better deformation performance and dislocation storage capacity within grains.

关键词： Superalloy Carbides Eutectic Crack