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企业基础研究的知识溢出效应研究

科学学研究 2025年第1期43卷 91-102页

作者：孟巧爽李乐逸王艺萌大连理工大学经济管理学院辽宁大连116024 大连理工大学科技创新创业与产业转型研究中心辽宁大连116024

企业基础研究是科技强国建设的重要基石,有助于推动科学研究与产业的深度融合。基于知识溢出视角,构建2000-2022年中国制造业上市公司科技文献与专利科技引文关联数据,探究企业科技文献对焦点企业专利的知识内溢机制和对竞争企业专利的... 详细信息

企业基础研究是科技强国建设的重要基石,有助于推动科学研究与产业的深度融合。基于知识溢出视角,构建2000-2022年中国制造业上市公司科技文献与专利科技引文关联数据,探究企业科技文献对焦点企业专利的知识内溢机制和对竞争企业专利的知识外溢机制。研究发现:(1)知识内溢促进焦点企业开展基础研究、知识外溢抑制焦点企业开展基础研究。(2)竞争企业专利对焦点企业科技文献的引用,有助于提升焦点企业专利数量。(3)与知识内溢相比,基础研究的知识外溢显著地抑制了焦点企业的财务绩效。异质性检验表明,知识溢出对非国有企业基础研究影响更明显。基础研究知识内溢促进高技术行业、低规模企业的应用研究,基础研究知识外溢促进非国有企业、高规模企业的应用研究。研究揭示企业基础研究的投入动机、溢出机制及市场效应,研究结论为夯实企业创新主体地位,引导基础研究、应用研究深度融合提供政策参考。

关键词：企业基础研究知识内溢知识外溢创新表现财务绩效

基于高密度遗传图谱的蓖麻种子大小性状QTL定位

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作物学报 2023年第3期49卷 719-730页

作者：杨俊芳王宙乔麟轶王亚赵宜婷张宏斌申登高王宏伟曹越山西农业大学经济作物研究所山西太原030031 山西农业大学农学院山西太原030031 山西农业大学社会服务部山西太原030031

蓖麻种子大小直接影响产量,不同的蓖麻材料间种子大小差异较大,深入研究蓖麻种子大小性状的遗传机制对蓖麻种子产业的发展具有重要意义。本研究以蓖麻两性自交系SL1为父本,雌性系HCH1为母本1(组合1)、雌性系HCH3为母本2(组合2),分别构... 详细信息

蓖麻种子大小直接影响产量,不同的蓖麻材料间种子大小差异较大,深入研究蓖麻种子大小性状的遗传机制对蓖麻种子产业的发展具有重要意义。本研究以蓖麻两性自交系SL1为父本,雌性系HCH1为母本1(组合1)、雌性系HCH3为母本2(组合2),分别构建F2、BC1群体。首先,分析2组遗传群体种子大小性状间的相关性。其次,利用全基因组测序技术(whole genome sequencing,WGS)对组合1的F2群体中的150个单株进行测序分析,构建高密度遗传图谱并结合种子大小性状表型数据进行数量性状座位(quantitative trait locus,QTL)定位分析。最后,对QTL区间包含的基因进行BLAST同源比对和KEGG通路富集分析确定候选基因。结果表明,不同组合群体的种子大小各性状间的相关性有差异,种子的长度和宽度相关性最显著。共检测到种子大小性状相关QTL位点18个,其中种子长度2个QTLs、种子宽度5个QTL、种子厚度4个QTL、百粒重7个QTL,分别分布在连锁群1、4、7、8、9、10上,LOD值介于3.77~7.40,变异贡献率介于0.71%~86.20%。基于这些分析,筛选到6个调控蓖麻种子大小的候选基因28470.m000435、29908.m006143、29848.m004589、27752.m000045、29683.m000480和29848.m004611。本研究为蓖麻种子大小相关基因的精细定位和克隆、分子标记辅助育种及基因功能的深入研究奠定了一定的理论基础。

关键词：蓖麻高密度遗传图谱种子大小 QTL定位 KEGG 候选基因

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Flow behavior and dynamic softening mechanism of Pt−10Ir precious alloy

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Transactions of Nonferrous Metals Society of China 2025年第1期35卷 225-242页

作者： Xin-pei ZHANG Jun-jie HE lin PI Quan FU Wen-yan ZHOU Jun CHENG Sheng-wen BAI Xuan ZHOU yi LIU Yong MAO Materials Genome Institute School of Materials and EnergyYunnan UniversityKunming 650091China Kunming Precious Materials&Technology Co. Ltd.Yunnan Precious Metals Laboratory Co.Ltd.Sino-Platinum Metals Co.Ltd.Kunming 650106China Kunming Institute of Precious Metals Kunming 650106China State Key Laboratory of Advanced Technologies for Comprehensive Utilization of Platinum Metals Sino-Platinum Metals Co.Ltd.Kunming 650106China Shaanxi Key Laboratory of Biomedical Metal Materials Northwest Institute for Non-ferrous Metal ResearchXi’an 710016China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China

The hot deformation behavior of Pt−10Ir alloy was studied under a wide range of deformation *** a low deformation temperature(950−1150℃),the softening mechanism is primarily dynamic *** addition,dynamic recrystallization by progressive lattice rotation near grain boundaries(DRX by LRGBs)and microshear bands assisted dynamic recrystallization(MSBs assisted DRX)coordinate the ***,it is difficult for the dynamic softening to offset the stain hardening due to a limited amount of DRXed *** a high deformation temperature(1250−1350℃),three main DRX mechanisms associated with strain rates occur:DRX by LRGBs,DRX by a homogeneous increase in misorientation(HIM)and geometric DRX(GDRX).With increasing strain,DRX by LRGBs is enhanced gradually under high strain rates;the“pinch-off”effect is enhanced at low strain rates,which was conducive to the formation of a uniform and fine microstructure.

关键词： platinum alloy hot deformation microstructure evolution dynamic recovery dynamic recrystallization

抗条锈病基因YrCH5026的遗传分析及分子定位

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华北农学报 2015年第5期30卷 7-15页

作者：侯丽媛乔麟轶张晓军李欣詹海仙畅志坚山西大学研究生院山西太原030006 山西省农业科学院作物科学研究所农业部黄土高原作物基因资源与种质创制重点实验室山西太原030031

CH5026是携带中间偃麦草抗病基因的渗入系。为了更好地利用CH5026,拓宽小麦抗性育种资源,对其抗条锈性来源和遗传模式进行了分析,对抗性基因进行了染色体定位并构建了遗传连锁图谱。在苗期和成株期对CH5026及其亲本分别接种条锈菌流行小... 详细信息

CH5026是携带中间偃麦草抗病基因的渗入系。为了更好地利用CH5026,拓宽小麦抗性育种资源,对其抗条锈性来源和遗传模式进行了分析,对抗性基因进行了染色体定位并构建了遗传连锁图谱。在苗期和成株期对CH5026及其亲本分别接种条锈菌流行小种CYR31、CYR32和CYR33。结果表明,CH5026在苗期和成株期对这3个条锈菌小种均表现出免疫或近免疫,且与其抗性供体TAI7045及其野生亲本中间偃麦草抗病侵染型相似。对其与感病品种(系)的杂交后代F1、F2、F2:3和BC1群体接种CYR32进行成株期抗性遗传机制分析,证实CH5026对CYR32的抗性由1对显性核基因控制。基因组原位杂交未检测到外源DNA杂交信号。用569对SSR引物对CH5026/台长29的192个F2群体进行分析,发现3个与抗性基因连锁的SSR标记:Xgwm210、Xwmc382和Xgpw7101,抗性基因位点与两翼邻近连锁标记Xwmc382和Xgpw7101的遗传距离分别为6.0,4.7 c M。利用中国春缺四体、双端体材料将该基因及其连锁标记定位在染色体2AS上。通过基因来源及连锁分子标记多态性比较,这个抗条锈病基因与已知定位于染色体2AS上的抗性基因不同,很可能是一个新的抗条锈病新基因,暂将其命名为Yr CH5026。

关键词：小麦中间偃麦草渗入系条锈病分子定位

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“三软”煤层采动巷道底鼓控制技术研究

煤炭技术 2021年第8期40卷 23-26页

作者：周文凯种阳李云茂秦艺璞乔懿麟陕西澄合合阳煤炭开发有限公司陕西渭南715300 陕西煤业化工技术研究院有限责任公司西安710100 煤炭绿色安全高效开采国家地方联合工程研究中心西安710100

为保证"三软"煤层条件下回采巷道的稳定,控制回采工作期间的底鼓灾害,以渭北矿区安阳煤矿5^(#)煤回采工作面为研究对象,运用电镜扫描试验分析泥岩遇水软化后的物理结构形态,通过理论研究和数值模拟试验分析得到5^(#)煤回采巷道复合型底... 详细信息

为保证"三软"煤层条件下回采巷道的稳定,控制回采工作期间的底鼓灾害,以渭北矿区安阳煤矿5^(#)煤回采工作面为研究对象,运用电镜扫描试验分析泥岩遇水软化后的物理结构形态,通过理论研究和数值模拟试验分析得到5^(#)煤回采巷道复合型底鼓变形机理,提出一种"支-卸"协同共用的底鼓控制技术,通过工业性试验验证了该地区同类型条件下底鼓控制技术的实用性。

关键词： “三软”煤层电镜扫描数值模拟底鼓变形

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采空区下近距离煤层巷道变形机制分析

煤炭技术 2015年第9期34卷 62-64页

作者：吴学明李亮乔懿麟廖敬龙陕西煤业化工技术研究院有限责任公司西安710065 煤炭绿色安全高效开采国家地方联合工程研究中心西安710065

针对采空区下近距离煤层巷道在掘进期间变形严重和难支护现状,考虑了开采技术和地质岩性等因素,采用理论分析与现场实测的方法对采空区下近距离煤层布置巷道的位置和应力分布状态进行了总结,分析了巷道围岩变形机制,为采空区下近距离煤... 详细信息

针对采空区下近距离煤层巷道在掘进期间变形严重和难支护现状,考虑了开采技术和地质岩性等因素,采用理论分析与现场实测的方法对采空区下近距离煤层布置巷道的位置和应力分布状态进行了总结,分析了巷道围岩变形机制,为采空区下近距离煤层巷道支护工艺及安全开采提供借鉴。

关键词：近距离煤层采空区掘巷变形机制

Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-Yu Zhao Juan-Han Yu yi-Hua Wang yi-Xin Liu Lu Xu lin Fu Ning yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report

Evaluation of Dual Emission Control Effects and Green Innovation Mechanisms: Evidence Based on the Construction of Free Trade Pilot Zones

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Huanjing Kexue/Environmental Science 2025年第3期46卷 1558-1572页

作者： Li, Shao-lin Shao, Dong-Xu Xue, Han-yi Center for Industrial and Business Organization Dongbei University of Finance and Economics Dalian116025 China School of Economics Southwestern University of Finance and Economics Chengdu611130 China

With the replication and promotion of the experience of pilot reform and innovation，as well as the continuous deepening of institutional openness，exploring green and low-carbon models has become an important measure for the country to promote the high-quality development of free trade pilot zones. This study focused on the core task of institutional innovation in free trade pilot zones，measured and quantified the level of green investment liberalization and green trade facilitation in each region，and explored the carbon emission dual control effect of free trade pilot zones using cutting-edge methods，such as group period average processing effect estimation（CATT），imputation，and stacked DID. The research conclusions were as follows：① The phased establishment of free trade pilot zones reduced the total carbon emissions by 27.40% and the carbon emission intensity by 14.30%. ② The pilot free trade zone achieved dual carbon emission control through the spillover effect of green innovation from foreign investment，the direct effect of green innovation from local enterprises，and the indirect effect of green innovation from digital trade. The comprehensive implementation of the negative list of market access，the signing and implementation of free trade agreements between China and other countries，and the increase of international green trade barriers have all had a significant positive regulatory effect on the dual control of carbon emissions in free trade pilot zones. The dual control effect of carbon emissions in the free trade pilot zone exhibited significant spatial spillover characteristics，showing maximum efficiency within a radius of 550 km，resulting in a reduction of 18.30% in the total carbon emissions of surrounding cities and a decrease of 10.10% in carbon emission intensity. Heterogeneity analysis showed that regions with higher levels of institutional innovation and government function transformation had a 13.10% and 13.70% higher total carbon emission control e

关键词： Low emission

Effect of heat treatment on microstructure and mechanical properties of a novel Al-Zn-Mg-Cu alloy

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China Foundry 2025年

作者： Yan-mei Yang Xin-chen Tang Ye-fei Li Xue-wei Fang Da-wei yi Zhi-yun Zhang qiao-ling Zheng Zhi-xi Wang Guo-yu Zhang Su Zhang Hao Cheng Yang He yi-bo Liu Zi-han Wu Ya-nan Chen yi-min Gao State Key Laboratory for Mechanical Behavior of Materials Xi'an Jiaotong University Xi'an Aerospace Precision Electromechanical Institute

Effects of solution and aging treatment on the microstructure and mechanical properties of a novel Al-Zn-Mg-Cu alloy by microalloying rare elements Sc and Er were studied. The results show that solution time has a visible influence on the microstructure and mechanical properties of the alloy. Specifically, as the solution time increases, the area fraction of the residual phase in the alloy decreases, and the shape of the grain becomes more spheroidal and coarser, leading to a decrease in hardness. This is attributed to the dissolution of strengthening phases during the solution treatment, which weakens the solid solution strengthening *** single-stage aging treatment shows an initial increase in strength and hardness of the alloy, followed by a decrease as the aging time is extended, until a steady state is achieved. The optimal single-aging conditions are found to be at 120 ℃ for 24 h, where the alloy exhibits an excellent combination of high strength and good ductility, with an ultimate tensile strength(UTS) of 523 MPa, yield strength(YS) of 482 MPa, and elongation(El)of 1.75%, respectively. Compared to single-stage aging, double-stage aging(120 ℃ for 24 h and then 150 ℃ for 52 h) significantly increases the elongation of the alloy(4.17%), but the UTS reduces to 465.29 MPa, and YS reduces to 410.64 MPa. Transmission electron microscopy(TEM) observations disclose that the grain size, the distribution spacing of precipitates along the grain boundary, and the width of the precipitation-free zone(PFZ) all undergo augmentation as the duration of the second stage aging process elongates.

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