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A historical review of hybrid rice breeding

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Journal of Integrative Plant Biology 2024年第3期66卷 532-545页

作者： Xiaoming Zheng Fei wei Cheng Cheng qian qian State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Yazhouwan National Laboratory Sanya City 572024China

The development of germplasm resources and advances in breeding methods have led to steady increases in yield and quality of rice (Oryza sativa L.). Three milestones in the recent history of rice breeding have contributed to these increases: dwarf rice breeding, hybrid rice breeding, and super rice breeding. On the 50th anniversary of the success of three-line hybrid rice,we highlight important scientific discoveries in rice breeding that were made by Chinese scientists and summarize the broader history of the field. We discuss the strategies that could be used in the future to optimize rice breeding further in the hope that China will continue to play a leading role in international rice breeding.

关键词： Chinese experience dwarf breeding hybrid rice breeding super rice breeding

Improved Efficiency Droop in a GaN-Based Light-Emitting Diode with an AlInN Electron-Blocking Layer

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Chinese Physics Letters 2012年第9期29卷 174-176页

作者： WEN Xiao-Xia YANG Xiao-Dong HE Miao LI Yang WANG Geng LU Ping-Yuan qian wei-ning LI Yun ZHANG wei-wei WU Wen-Bo CHEN Fang-Sheng DING Li-Zhen Laboratory of Micro-nano Photonic Functional Materials and Devices of Guangdong Province Institute of Optoelectronic Materials and TechnologySouth China Normal UniversityGuangzhou 510631 The School of Chemistry The University of St.AndrewsFife KY169SU.K.

GaN-based light-emitting devices(LEDs)with different electron blocking layers are theoretically studied and compared by using the advanced physical models of a semiconductor device simulation *** is found that the structure with an AlInN electron blocking layer shows improved light output power,lower current leakage and efficiency *** on numerical simulation and analysis,these improvements of the electrical and optical characteristics are mainly accounted for by efficient electron *** can be concluded that Auger recombination is responsible for the dominant origin of the efficiency droop of a GaN-based LED as current increases.

关键词： Efficiency GaN Electron

Glial progenitor heterogeneity and plasticity in the adult spinal cord

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Neural Regeneration Research 2024年第12期19卷 2567-2568页

作者： Haichao wei Jia qian Wu Department of Neurosurgery McGovern Medical SchoolThe University of Texas Health Science Center at HoustonHoustonTXUSA Center for Stem Cell and Regenerative Medicine UT Brown Foundation Institute of Molecular MedicineHoustonTXUSA MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences HoustonTXUSA

Glial progenitor cells were reported to have the capacity to generate various types of cells in both the central nervous system(CNS)and peripheral nervous *** progenitor cells can respond to diverse environmental signals and transform into distinct populations,each serving specific ***,the adult spinal cord hosts various populations of glial progenitors,a region integral to the central nervous *** development,glial progenitors express glial fibrillary acidic protein(GFAP;Dimou and Gotz,2014).However,the specific identities of GFAP-expressing progenitors in the adult spinal cord were not thoroughly investigated.

关键词： functions plasticity thoroughly

Novel Adaptive Memory Event-Triggered-Based Fuzzy Robust Control for Nonlinear Networked Systems via the Differential Evolution Algorithm

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IEEE/CAA Journal of Automatica Sinica 2024年第8期11卷 1836-1848页

作者： wei qian Yanmin Wu Bo Shen School of Electrical Engineering and Automation Henan Polytechnic UniversityJiaozuo 454000China College of Information Science and Technology Donghua UniversityShanghai 201620China

This article mainly investigates the fuzzy optimization robust control issue for nonlinear networked systems characterized by the interval type-2(IT2)fuzzy technique under a differential evolution *** provide a more reasonable utilization of the constrained communication channel,a novel adaptive memory event-triggered(AMET)mechanism is developed,where two event-triggered thresholds can be dynamically adjusted in the light of the current system information and the transmitted historical *** conditions with less conservative design of the fuzzy imperfect premise matching(IPM)controller are presented by introducing the Wirtinger-based integral inequality,the information of membership functions(MFs)and slack ***,under the IPM policy,a new MFs intelligent optimization technique that takes advantage of the differential evolution algorithm is first provided for IT2 TakagiSugeno(T-S)fuzzy systems to update the fuzzy controller MFs in real-time and achieve a better system control ***,simulation results demonstrate that the proposed control scheme can obtain better system performance in the case of using fewer communication resources.

关键词： Adaptive memory event-triggered(AMET) differential evolution algorithm fuzzy optimization robust control interval type-2(IT2)fuzzy technique.

Complex interactions among insect viruses-insect vector-arboviruses

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Insect Science 2024年第3期31卷 683-693页

作者： Hui Wang qian Chen Taiyun wei State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops Vector-borne Virus Research CenterFujian Agriculture and ForestryUniversityFuzhouChina

Insects are the host or vector of diverse viruses including those that infect vertebrates,plants,and *** viruses reside inside their insect hosts and are vertically transmitted from parent to *** insect virus-host relationship is intricate,as these viruses can impact various aspects of insect biology,such as development,reproduction,sex ratios,and ***-borne viruses(arboviruses)that cause substantial global health or agricultural problems can also be vertically transmitted to insect vector *** infections with insect viruses and arboviruses are common in *** coinfections involve complex interactions,including synergism,dependence,and *** studies have shed light on the influence of insect viruses on the competence of insect vectors for *** this review,we focus on the biological effects of insect viruses on the transmission of arboviruses by *** also discuss the potential mechanisms by which insect viruses affect the ability of hosts to transmit arboviruses,as well as potential strategies for disease control through manipulation of insect *** of the interactions among insect vectors,insect viruses and arboviruses will provide new opportunities for development of innovative strategies to control arbovirus transmission.

关键词： arbovirus insect biology insect vectors insect virus interaction transmission

Distributions of Visual Receptive Fields from Retinotopic to Craniotopic Coordinates in the Lateral Intraparietal Area and Frontal Eye Fields of the Macaque

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Neuroscience Bulletin 2024年第2期40卷 171-181页

作者： Lin Yang Min Jin Cong Zhang ning qian Mingsha Zhang Key Laboratory of Cognitive Neuroscience and Learning Division of PsychologyBeijing Normal UniversityBeijing 100875China Institute of Neuroscience Key Laboratory of Primate NeurobiologyCAS Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai 200031China Department of Neuroscience and Zuckerman Institute Columbia UniversityNew York 10027USA

Even though retinal images of objects change their locations following each eye movement,we perceive a stable and continuous *** possible mechanism by which the brain achieves such visual stability is to construct a craniotopic coordinate by integrating retinal and extraretinal *** have been several proposals on how this may be done,including eye-position modulation(gain fields)of retinotopic receptive fields(RFs)and craniotopic *** the present study,we investigated coordinate systems used by RFs in the lateral intraparietal(LIP)cortex and frontal eye fields(FEF)and compared the two *** mapped the two-dimensional RFs of neurons in detail under two eye fixations and analyzed how the RF of a given neuron changes with eye position to determine its coordinate *** same recording and analysis procedures were applied to the two brain *** found that,in both areas,RFs were distributed from retinotopic to craniotopic *** was no significant difference between the distributions in the LIP and *** a small fraction of neurons was fully craniotopic,whereas most neurons were between the retinotopic and craniotopic *** distributions were strongly biased toward the retinotopic side but with significant craniotopic *** results suggest that there is only weak evidence for craniotopic RFs in the LIP and FEF,and that transformation from retinotopic to craniotopic coordinates in these areas must rely on other factors such as gain fields.

关键词： Reference frames Eye-centered Headcentered Visual stability

Inferring the Effects of Protein Variants on Protein-Protein Interactions with Interpretable Transformer Representations

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Research 2024年第2期2023卷 473-489页

作者： Zhe Liu wei qian Wenxiang Cai weichen Song weidi Wang Dhruba Tara Maharjan Wenhong Cheng Jue Chen Han Wang Dong Xu Guan ning Lin Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineSchool of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina Shanghai Key Laboratory of Psychotic Disorders ShanghaiChina School of Information Science and Technology Institute of Computational BiologyNortheast Normal UniversityChangchunChina Department of Electrical Engineering and Computer Science University of MissouriColumbiaMO 65211USA Christopher S.Bond Life Sciences Center University of MissouriColumbiaMO 65211USA

Identifying pathogenetic variants and inferring their impact on protein-protein interactions sheds light on their functional consequences on *** by the availability of experimental data on the consequences of protein interaction,most existing methods focus on building models to predict changes in protein binding ***,we introduced MIPPI,an end-to-end,interpretable transformer-based deep learning model that learns features directly from sequences by leveraging the interaction data from *** was specifically trained to determine the types of variant impact(increasing,decreasing,disrupting,and no effect)on protein-protein *** demonstrate the accuracy of MIPPI and provide interpretation through the analysis of learned attention weights,which exhibit correlations with the amino acids interacting with the ***,we showed the practicality of MIPPI in prioritizing de novo mutations associated with complex neurodevelopmental disorders and the potential to determine the pathogenic and driving ***,we experimentally validated the functional impact of several variants identified in patients with such ***,MIPPI emerges as a versatile,robust,and interpretable model,capable of effectively predicting mutation impacts on protein-protein interactions and facilitating the discovery of clinically actionable variants.

关键词： consequences weights versatile

Promising prognostic value of ATP binding cassette transporters and their correlation with tumor-infiltrating immune cells in lung adenocarcinoma

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Genes & Diseases 2024年第5期11卷 91-93页

作者： Linzi wei qian Yu Xueying Yang Department of Thoracic Surgery The Fourth Affiliated Hospital of China Medical UniversityShenyangLiaoning 110032China

Lung cancer(LC)is a prevalent and fatal malignancy,with high incidence and mortality rates.1 ATP binding cassette(ABC)transporters,a superfamily of integral membrane proteins,use ATP hydrolysis to facilitate substrate transport across cellular membranes.2 The pivotal role of ABC transporters in tumorigenesis was initially established by Mochida,3 who demonstrated that the loss of ABCB1 suppresses intestinal polyp formation and tumor progression in *** investigations have reported correlations between ABC transporters and the tumor microenvironment and cancer immunotherapy response,suggesting their modulatory effects on tumor progression and immunotherapy.

关键词： mortality adenocarcinoma Lung

Robot trajectory planning for autonomous 3D reconstruction of cockpit in aircraft final assembly testing

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Chinese Journal of Aeronautics 2024年第3期37卷 332-350页

作者： Yanzhe WANG Zemin PAN qian YANG Changxi DENG Yanding wei The State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027China School of Information Science and Engineering NingboTech UniversityNingbo 315100China AVIC Xi’an Aircraft Industry(Group)Company Ltd. Xi’an 710089China Key Laboratory of Advanced Manufacturing Technology of Zhejiang Province School of Mechanical EngineeringZhejiang UniversityHangzhou 310027China

The trend towards automation and intelligence in aircraft final assembly testing has led to a new demand for autonomous perception of unknown cockpit operation scenes in robotic collaborative airborne system *** address this demand,a robotic automated 3D reconstruction cell which enables to autonomously plan the robot end-camera’s trajectory is developed for image acquisition and 3D modeling of the cockpit operation scene.A continuous viewpoint path planning algorithm is proposed that incorporates both 3D reconstruction quality and robot path quality into optimization *** metrics for viewpoint position paths and orientation paths are introduced together for the first time in 3D *** ensure safe and effective movement,two spatial constraints,Domain of View Admissible Position(DVAP)and Domain of View Admissible Orientation(DVAO),are implemented to account for robot reachability and collision *** using diffeomorphism mapping,the orientation path is transformed into 3D,consistent with the position *** orientation and position paths can be optimized in a unified framework to maximize the gain of reconstruction quality and path smoothness within DVAP and *** reconstruction cell is capable of automatic data acquisition and fine scene modeling,using the generated robot C-space *** and physical scene experiments have confirmed the effectiveness of the proposed method to achieve highprecision 3D reconstruction while optimizing robot motion quality.

关键词： Aircraft assembly testing Aircraft cockpit 3D modeling Camera viewpoint Robot trajectory planning