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Mediated protective effect of electroacupuncture pretreatment by miR-214 on myocardial ischemia/reperfusion injury

Journal of Geriatric Cardiology 2014年第4期11卷 303-310页

作者： pei-Yu LIU yi TIAN Shi-Yuan XU Department of Anesthesiology ZhuJiang Hospital of Southern Medicine University Guangzhou 510282 Guangdong Province China Department of Anesthesiology Hainan Provincial Corps Hospital of Chinese People's Armed Police Forces Haikou 570203 Hainan Province China Department of Anesthesiology Haikou People's Hospital Haikou 570203 Hainan Province China

Background Electroacupuncture pretreatment plays a protective role in myocardial ischemia/reperfusion （I/R） injury and microRNAs （miRNAs） could act on various facets of cardiac function. However, the role of miRNAs in the cardioprotection by electroacupuncture pre-treatment on myocardial I/R injury remains unknown. The purpose of the study was to examine whether miR-214 was involved in cardio-protection by electroacupuncture. Methods Using rat myocardial I/R model, we examined the role of electroacupuncture pretreatment in myocardial I/R injury and analyzed the changes in the expression of miR-214. In addition, I/R was simulated in vitro by performing oxy-gen-glucose deprivation （OGD） on H9c2 cell cultures, and the effect of electroacupuncture pretreatment on I/R injury as well as expressional level of miR-214 were examined in vitro. Furthermore, the miR-214 mimic was transfected into OGD-treated H9c2 cells, we analyzed the cell apoptosis, lactate dehydrogenase （LDH） and creatine kinase （CK） activities, intracellular free Ca2＋concentration （[Ca2＋]i） as well as the relative protein levels of sodium/calcium exchanger 1（NCX1）, BCL2-like 11 （BIM）, calmodulin-dependent protein kinase IIδ（CaMKIIδ） and Cyclophilin D （CypD）. Results The in vivo results revealed that compared with the I/R group, the electroacupuncture pretreatment group showed significant decreased myocardial infarct size, as well as the increased indices of the cardiac function, including heart rate, mean arterial pressure, left ventricular systolic pressure and maximal rate for left ventricular pressure rising and declining （±dp/dt max）. In addition, electroacupuncture pretreatment could inhibit the elevation of LDH and CK activities induced by I/R injury. The quantitative PCR （qPCR） results demonstrated electroacupuncture pretreatment could provide cardioprotection against myocardial I/R injury in rats with miR-214 up-regulation. In the meanwhile, in vitro, electroacupuncture pretreatment protected H9c2 c

关键词： I/R injury miR-214 Electroacupuncture Protective effect

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BS sleeping strategy for energy-delay tradeoff in wireless-backhauling UDN

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Science China(Information Sciences) 2019年第4期62卷 140-156页

作者： pei LI yi SHEN Faisal SAHITO Zhiwen PAN Xiaohu YOU National Mobile Communications Research Laboratory Southeast University

Ultra-dense network (UDN) has been recognized as a promising technology for 5G. Although turning off low-load base stations (BSs) can improve energy efficiency, it may cause degradation of delay performance. This makes energy-delay tradeoff (EDT) an important topic. In this paper, a theoretical framework for EDT, in wireless-backhauling UDN, is developed. First, we investigate association probabilities of UEs and transmission probabilities of BSs. Expressions for energy consumption and network packet delay are obtained and the impact that BS sleeping ratio has on energy consumption and packet delay are ***, we formulate the EDT problem as a cost minimization problem to select the optimal set of sleeping small cells. To solve the EDT optimization problem, a locally optimal sleeping ratio for EDT is obtained using the dynamic gradient iteration algorithm and we prove that it can converge to the global optimal sleeping ratio. Then, queue-aware and channel-queue-aware sleeping strategies are proposed to find the optimal set of sleeping small cells according to the optimal sleeping ratio. We then see that the simulation and numerical results confirm the effectiveness of the proposed sleeping schemes.

关键词： ultra-dense networks sleeping ratio sleeping strategy wireless backhaul energy-delay tradeoff

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Numerical study of submerged bending vegetation under unidirectional flow

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Water Science and Engineering 2024年第1期17卷 92-100页

作者： pei-pei Zhang yi-qing Gong Ken Vui Chua Jie Dai Jing-qiao Mao College of Water Conservancy and Hydropower Engineering Hohai UniversityNanjing 210098China Institute of Water Science and Technology Hohai UniversityNanjing 210098China School of Engineering Cardiff UniversityCardiff CF243AAUK

Submerged vegetation commonly grows and plays a vital role in aquatic ecosystems,but it is also regarded as a barrier to the passing *** simulations of flow through and over submerged vegetation were carried out to investigate the effect of vegetation density on flow *** simulations were computationally set up to replicate flume experiments,in which vegetation was mimicked with flexible plastic *** fluid-structure interaction between flow and flexible vegetation was solved by coupling the two modules of the COMSOL *** cases with different vegetation densities were simulated,and the results were successfully validated against the experimental *** contours of the simulated time-averaged streamwise velocity and Reynolds stress were extracted to highlight the differences in mean and turbulent flow *** turbulence intensity was found to be more sensitive to vegetation density than the time-averaged *** developing length increased with the spacing between *** snapshots of the bending vegetation under instantaneous velocity and vorticity revealed that flexible vegetation responded to the effects of eddies in the shear layer by swaying *** first two rows of vegetation suffered stronger approaching flow and were prone to more streamlined *** addition,the origin of tip vortices was investigated via the distribution of *** results reveal the variation of flow properties with bending submerged vegetation and provide useful reference for optimizationofrestorationprojects.

关键词： Computational fluid dynamics Fluid-structure interaction Turbulence Flexible and submerged vegetation

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A Privacy-Preserving Scheme for Location-Based Services in the Internet of Vehicles

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Journal of Communications and Information Networks 2021年第4期6卷 385-395页

作者： Jiaqi Huang yi qian Rose Qingyang Hu University of Central Missouri 116 W South StWarrensburgMO 64093USA Unviersity of Nebraska-Lincoln 1110 S 67th StOmahaNE 68182USA Utah State University LoganUT 84322USA

Ubiquitous information exchange is achieved among connected vehicles through the increasingly smart *** concept of conventional vehicular ad hoc network is gradually transformed into the Internet of vehicles(IoV).Meanwhile,more and more locationbased services(LBSs)are created to provide convenience for ***,the frequently updated location information sent to the LBS server also puts user location privacy at ***,preserve user location privacy while allowing vehicles to have high-quality LBSs is a critical *** solutions have been proposed in the literature to preserve location ***,most of them cannot provide real-time LBS with accurate location *** this paper,we propose a novel location privacy-preserving scheme,which allows vehicles to send accurate real-time location information to the LBS server while preventing being tracked by *** the proposed scheme,a vehicle utilizes the location information of selected shadow vehicles,whose route diverge from the requester,to generate multiple virtual trajectories to the LBS server so as to mislead *** results show that our proposed scheme achieves a high privacy-preserving level and outperforms other state-of-the-art schemes in terms of location entropy and tracking success ratio.

关键词： location privacy location-based service internet of vehicles vehicular networks

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Measuring orbital angular momentum of vortex beams in optomechanics

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Frontiers of physics 2021年第3期16卷 177-183页

作者： Zhucheng Zhang Jiancheng pei yi-Ping Wang Xiaoguang Wang Zhejiang Institute of Modern Physics Department of PhysicsZhejiang UniversityHangzhou310027China College of Science Northwest A&F UniversityYangling712100China Graduate School of China Academy of Engineering Physics Beijing100193China

Measuring the orbital angular momentum(OAM)of vortex beams,including the magnitude and the sign,has great application prospects due to its theoretically unbounded and orthogonal ***,the sign-distinguishable OAM measurement in optomechanics is proposed,which is achieved by monitoring the shift of the transmission spectrum of the probe field in a double Laguerre-Gaussian(LG)rotational-cavity *** with the traditional single LG rotational cavity,an asymmetric optomechanically induced transparency window can occur in our ***,the position of the resonance valley has a strong correlation with the magnitude and sign of *** originally comes from the fact that the effective detuning of the cavity mode from the driving field can vary with the magnitude and sign of OAM,which causes the spectral shift to be directional for different signs of *** scheme solves the shortcoming of the inability to distinguish the sign of OAM in optomechanics,and works well for high-order vortex beams with topological charge value±45,which is a significant improvement for measuring OAM based on the cavity optomechanical system.

关键词： orbital angular momentum optomechanically induced transparency Laguerre-Gaussian rotational-cavity system optomechanics

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Perihematomal Perfusion Typing and Spot Sign of Acute Intracerebral Hemorrhage with Multimode Computed Tomography: A Preliminary Study

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Chinese Medical Sciences Journal 2014年第3期29卷 139-143页

作者： Xin-yi Hou pei-yi Gao Department of Neuroradiology Beijing Tiantan Hospital Capital Medical University

Objective To explore the perihematomal perfusion typing and spot sign on computed tomography angiography(CTA) source images in order to assist in individualizing therapeutic decisions for patients with intracerebral hemorrhage by possibly forecasting perihematomal ischemia and hematoma enlargement. Methods We examined 58 patients with spontaneous intracerebral hemorrhage by computed tomography perfusion and CTA within 6 hours after symptom onset. Hematoma volumes were determined from non-contrast CT images and compared between first and second CT images. The perfusion of hematoma region and perihematoma region was evaluated for presence or absence of the perihematomal penumbra. Three kinds of perihematoma perfusion typing were defined according to the perfusion of hematoma region and perihematoma region. CTA source images was reviewed to make sure presence or absence of the spot sign. Results Finally, 53 patients(34 males, 19 females) were enrolled in our study according to exclusion criteria. Finally, 21 patients were classified into the normal group, 23 patients were classified into the mild group, and 9 patients were classified into the severe group. There were significant differences in hematoma size between the presence and absence of the perihematomal penumbra group(P<0.05). Thirteen(24.5%) patients presented with spot sign. Hematoma expansion occurred in 15(28.3%) patients on follow-up. In which 12 patients were with spot sign. Sensitivity, specificity, positive predictive value, and negative predictive value for expansion were 80.0%, 97.4%, 92.3%, and 92.5%, respectively. Conclusion In acute intracerebral hemorrhage patients, the perihematoma perfusion typing and CTA spot sign provide more radiological information that might assist in individualizing therapeutic decisions for patients by possibly forecasting perihematomal ischemia and hematoma enlargement.

关键词： intracerebral hemorrhage computed tomography perfusion computed tomography angiography

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PM-compact Graphs and Vertex-deleted Subgraphs

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Acta Mathematicae Applicatae Sinica 2022年第4期38卷 955-965页

作者： yi-pei ZHANG Xiu-mei WANG Jin-jiang YUAN School of Mathematics and Statistics Zhengzhou UniversityZhengzhou 450001China

The perfect matching polytope of a graph G is the convex hull of the incidence vectors of all perfect matchings of G.A graph G is PM-compact if the 1-skeleton graph of the prefect matching polytope of G is ***,a matchable graph G is PM-compact if and only if for each even cycle C of G,G-V(C)has at most one perfect *** paper considers the class of graphs from which deleting any two adjacent vertices or nonadjacent vertices,respectively,the resulting graph has a unique perfect *** PM-compact graphs in this class of graphs are presented.

关键词： perfect matching nice cycle bicritical graph PM-compact graph

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Rapid and sensitive detection of pesticides by surface-enhanced Raman spectroscopy technique based on glycidyl methacrylate-ethylene dimethacrylate(GMA-EDMA) porous material

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Chinese Chemical Letters 2013年第4期24卷 332-334页

作者： Qing-Qing Li yi-Ping Du ying Xu Xuan Wang Shi-qian Ma Jin-pei Geng Peng Cao Tao Sui Shanghai Key Laboratory of Functional Materials Chemistry & Research Centre of Analysis and Test East China University of Science and Technology Yantai Entry-Exit Inspection and Quarantine Bureau

A novel method of fast and sensitive SERS detection using GMA-EDMA porous material combined with a miniature device was reported in this study. A 100 μL solution containing sample, silver colloid and NaC1 was evenly mixed to ensure the sample molecules would adsorb onto silver nanoparticles. Then the mixture was added onto the porous material surface slowly, so that the aggregation of silver colloid would stay on the surface while the liquid components would flow away. This technology can improve the sensitivity of SERS detection. By this method, two pesticides tricyclazole and paraquat were successfully detected at concentrations of 5 × 10 3 mg/L and I × 10-3 mg/L, respectively.

关键词： rSurface-enhanced Raman spectroscopyGMA-EDMA porous materialTricyclazoleParaquat

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Decolorization of reactive brilliant red K-2BP by white rot fungus under sterile and non-sterile conditions

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Journal of Environmental Sciences 2006年第3期18卷 428-432页

作者： GAO Da-wen WEN Xiang-hua qian yi State Key Joint Laboratory of Environmental Simulation and Pollution Control Department of Environment Science and Engineering TsinghuaUniversity Beijing 100084 China.

Almost all the studies both domestic and international using white rot fungus for dye wastewater treatment are performed under sterile conditions. However, it is obviously unpractical that wastewater with dyes is treated under sterile conditions. A feasible study was made for using white rot fungus Phanerochaete chrysosporium to degrade reactive brilliant red K-2BP dye under non-sterile conditions. The results showed that there was no decolorizing effect under non-sterile condition if white rot fungus was incubated under non-sterile condition, and the decolorization was always near to 0% during decolorizing test for 3 d; in the meantime, a lot of yeast funguses were found in liquid medium when white rot fungus was incubated under non-sterile conditions; however, if white rot fungus was incubated under sterile condition firstly, its decolorization was above 90% under non-sterile condition, which was similar to that of sterile condition. So we point out that the treating process for wastewater with dyes should be divided into two stages. The first stage is that white rot fungus should be incubated under sterile conditions, and the second stage is that reactive brilliant red K-2BP is decolorized under non-sterile conditions. The method not only save the operation cost which decolorizing reactive brilliant red K-2BP under sterile condition, but also provide the feasibility for using white rot fungus to degrade wastewater with dyes under non-sterile conditions.

关键词： white rot fungus Phanerochaete chrysosporium reactive brilliant red K-2BP decolorization non-sterile condition

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Produced-water treatment: Application and research of combined fiber coalescence technique in offshore oilfield

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Petroleum Science 2023年第1期20卷 569-576页

作者： Pin-yi Dai yi-qian Liu Hao Lu Yu-Dong Li qiang Yang School of Mechanical and Power Engineering East China University of Science and TechnologyShanghai200237China

When the process of extraction of oil from an offshore oilfield enters the advanced stages,the water content in the extracted fluid can be above 90%.The water quality is complex with many types of pollutants and highly emulsified ***,a key consideration in the production process of offshore oilfields is the efficient and economical treatment of the oil-containing produced water to make it suitable for discharge and recover oil *** this study,we developed a hydrophilic and hydrophobic combined fiber coalescence separator with composite fiber shapes using fiber induction and X/*** separator is designed based on experimental observations of the mechanism of structure coalescence in the physical oil removal method.A pilot test was performed on an oil exploration platform in the Bohai *** the designed flow rate,the separator reduced the total concentration of petroleum in the produced water from 2000 to 3000 mg/L to below 60 mg/L,with an average oil removal efficiency of 98.24%.Furthermore,it effectively reduced the number of organic compounds present in the water from 120 to 17 and removed 70% of the *** test results show that the proposed device can be used fr produced-water treatment on offshore platforms.

关键词： Combined fiber coalescence Production water Oil-water separation X/U weaving

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