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Agricultural Sciences in China 2009年第1期8卷 68-75页

作者： qian guo-liang hu bai-shi jiang ying-hua liu feng-quan Department of Plant Pathology College of Plant Protection Nanjing Agricultural University~Key Laboratory of Monitoring and Managementof Crop Diseases and Pest Insects Ministry of Agriculture Nanjing 210095 P.R.China

Strain OH11, a Gram-negative, nonspore forming, rod-shaped bacterium with powerful antagonistic activity, was isolated from rhizosphere of green pepper in jiangsu Academy of Agricultural Sciences of China and characterized to determine its taxonomic position. 16S rRNA gene sequence analysis revealed that strain OH11 belongs to the Gammaproteobacteria and had the highest degree of sequence similarity to Lysobacter enzymogenes strain C3 （AY074793）（99%）, Lysobacter enzymogenes strain N4-7 （U89965）（99%）, Lysobacter antibioticus strain （AB019582）（97%）, and Lysobacter gummosus strain （AB16136）（97%）. Chemotaxonomic data revealed that strain OHI 1 possesses a quinine system with Q-8 as the predominant compound and C15：0 iso, C17：1 iso ω9c as the predominant iso-branched fatty acids, all of which corroborated the assignment of strain OH11 to the genus Lysobacter. Results of DNA-DNA hybridization and physiological and biochemical tests clearly showed that strain OH11 was classified as Lysobacter enzymogenes. Strain OH11 could produce protease, chitinase, and β-1,3-glucanase. It showed strong in vitro antifungal activity against Rhizoctonia solani, Sclerotinia scletotiorum, and several other phytopathogenic fungi. This is the first report of identification and characterization of Lysobacter enzymogenes as a biological control agent of plant diseases in China.

关键词： Lysobacter enzymogenes identification characterization biological control

Production and Characterization of Polyclonal Antibody for the N-Methylcarbamate Insecticide Metolcarb

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Agricultural Sciences in China 2007年第2期6卷 175-179页

作者： ZHANG Qi Ph D candidate[a]&Email:zhangqi521x@*** LI Tie-jun[a] Zhu Xiao-xia[a] XU Li-na[a] liu feng-quan[a]&Email:fqliu20011@*** Professor hu bai-shi[a] jiang ying-hua[a] CAO Bin[b] [a]Key Laboratory of Monitoring and Management of Plant Diseases and Pests Ministry of Agriculture/Department of Plant Protection Nanjing Agricultural University Nanjing 210095 P.R.China[b]Pesticide Research Institute of Jiangsu Province Nanjing 210036 P.R.China

The hapten, 3-{ [1-（3-（methyl）phenyloxy）-carbonyl]amino}propanoic acid （HOM）, mimicking the analyte metolcarb, was synthesized and verified by mass spectrometry （MS） and 1H-nuclear magnetic resonance spectrometry （1H-NMR）. Then, HOM was conjugated with the carrier proteins bovine serum albumin （BSA） and ovalbumin （OVA） with stoichiometric amounts of N-hydroxysuccinimide/dicyclohexylcarbodimide （NHS/DCC） using the activated ester method. Polyclonal antibodies were raised against the conjugate of HOM-BSA in rabbits. Antiserum titres were determined by noncompetitive indirect ELISA procedures and the titer of pAb01 reached 1.28 × 10^6. The cross-reactivities of the structurally related Nmethylcarbamate insecticides were 0.0% except for dimethacarb. These results indicate that the antibody pAb01 with strong affinity and high specificity can be used to develop a sensitive and rapid detection protocol for metolcarb residue.

关键词： metolcarb antigen polyclonal antibody antiserum characterization ELISA

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梨火疫病菌在中国的潜在分布及入侵风险分析

中国农业科学 2007年第5期40卷 940-947页

作者：陈晨陈娟胡白石白艺珍姜英华刘凤权南京农业大学农业部病虫检测与治理重点开放实验室南京农业大学农业部病虫检测与治理重点开放实验室南京210095

【目的】细菌性梨火疫病最早发生在北美洲,随着水果贸易等人为因素向世界其它地区传播。对当地的生物多样性和经济带来了极其严重的威胁,亟需对其在中国的适生区进行预测。【方法】苹果开花期的温度和降水量是影响梨火疫病菌适生分布的... 详细信息

【目的】细菌性梨火疫病最早发生在北美洲,随着水果贸易等人为因素向世界其它地区传播。对当地的生物多样性和经济带来了极其严重的威胁,亟需对其在中国的适生区进行预测。【方法】苹果开花期的温度和降水量是影响梨火疫病菌适生分布的关键气候因子,本研究根据这一生物学特性及生态环境因子,应用地理信息系统分析得出了梨火疫病在中国两个苹果优势产区的潜在定殖区域。【结果】用该方法对梨火疫病在欧洲的发生情况的预测结果与其历史分布记录相符,使用相同的空间建模方法对梨火疫病在渤海湾和黄土高原两个苹果优势栽培产区的潜在定殖区域进行风险评估,结果表明这两大苹果产区中优先扶持的县大多处于梨火疫病发生的高风险范围。【结论】梨火疫病在中国的大部分地区适生,在有适宜寄主分布的地区,就可能严重发生。

关键词：生物入侵梨火疫病菌地理信息系统潜在分布区风险分析

利用PCR技术专化性检测水稻细菌性条斑病菌

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植物病理学报 2008年第1期38卷 1-5页

作者：张华姜英华胡白石刘凤权许志刚南京农业大学农业部病虫监测与治理重点开放实验室南京210095

设计水稻细菌性条斑病菌的专化性引物,并建立相应的PCR检测体系,分别对31株水稻细菌性条斑病菌和15株水稻白叶枯病菌及其它相关菌株进行了测试。结果表明,建立的PCR检测体系可专化性检测水稻细菌性条斑病菌,而水稻白叶枯病菌和其它菌株... 详细信息

设计水稻细菌性条斑病菌的专化性引物,并建立相应的PCR检测体系,分别对31株水稻细菌性条斑病菌和15株水稻白叶枯病菌及其它相关菌株进行了测试。结果表明,建立的PCR检测体系可专化性检测水稻细菌性条斑病菌,而水稻白叶枯病菌和其它菌株均没有扩增信号。检测灵敏度可以达到20个细菌菌体,从自然发病和人工接种发病的水稻种子成功地检测出条斑病菌。实现了对水稻细菌性条斑病菌的快速和专化性检测。

关键词：水稻细菌性条斑病菌专化性引物 PCR技术检测

The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo Yong-Heng Zhao Gang Zhao Li-Cai Deng Xiao-Wei liu Yi-Peng Jing Gang Wang Hao-Tong Zhang Jian-Rong shi Xiang-Qun Cui Yao-quan Chu guo-Ping Li Zhong-Rui bai Yue Wu Yan Cai Shu-Yun Cao Zi-huang Cao Jeffrey L.Carlin Hai-Yuan Chen Jian-Jun Chen Kun-Xin Chen Li Chen Xue-Lei Chen Xiao-Yan Chen ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei feng Jian-Ning Fu Peng Gao Xue-Fei Gong Bo-Zhong Gu Yan-Xin guo Zhan-Wen Han Bo-liang He Jin-liang Hou Yong-hui Hou Wen Hou Hong-Zhuan hu Ning-Sheng hu Zhong-Wen hu Zhi-ying huo Lei Jia Fang-hua jiang Xiang jiang Zhi-Bo jiang Ge Jin Xiao Kong Xu Kong Ya-Juan Lei Ai-hua Li Chang-hua Li Guang-Wei Li Hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li Yan Li Yin-Bi Li Ye-Ping Li Yuan liang Chien-Cheng Lin Chao liu Gen-Rong liu Guan-Qun liu Zhi-Gang liu Wen-Zhi Lu Yu Luo Yin-Dun Mao Heidi Newberg Ji-Jun Ni Zhao-Xiang Qi Yong-Jun Qi shi-Yin Shen huo-Ming shi Jing Song Yi-Han Song Ding-qiang Su Hong-Jun Su Zheng-Hong Tang Qing-Sheng Tao Yuan Tian Dan Wang Da-Qi Wang feng-Fei Wang guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-Ling Wang Jian-Ping Wang Jun-Xian Wang Lei Wang Meng-Xin Wang Shou-Guan Wang Shu-Qing Wang Xia Wang Ya-Nan Wang You Wang Yue-Fei Wang You-Fen Wang Peng Wei Ming-Zhi Wei Hong Wu Ke-Fei Wu Xue-Bing Wu Yu-Zhong Wu Xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu Yan Xu Tai-Sheng Yan De-hua Yang Hai-feng Yang hui-Qin Yang Ming Yang Zheng-Qiu Yao Yong Yu hui Yuan Hai-Bo Yuan Hai-Long Yuan Wei-Min Yuan Chao Zhai En-Peng Zhang hua-Wei Zhang Jian-Nan Zhang Li-Pin Zhang Wei Zhang Yong Zhang Yan-Xia Zhang Zheng-Chao Zhang Ming Zhao Fang Zhou Xu Zhou Jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques： spectroscopic survey—data release—catalog

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植物土传病原菌拮抗细菌的筛选与鉴定

中国生物防治 2005年第4期21卷 260-264页

作者：姜英华胡白石刘凤权南京农业大学植物保护学院南京210095

从作物根际土壤中分离到1056株细菌,筛选出7个具有较强拮抗活性的菌株。室内测定对水稻纹枯病菌、辣椒疫病菌、瓜果腐霉、油菜菌核病菌、棉花枯萎病菌、茄根腐病菌、棉花黄萎病菌、番茄青枯病菌、甘蓝黑腐病菌等重要土传病原菌有较强拮... 详细信息

从作物根际土壤中分离到1056株细菌,筛选出7个具有较强拮抗活性的菌株。室内测定对水稻纹枯病菌、辣椒疫病菌、瓜果腐霉、油菜菌核病菌、棉花枯萎病菌、茄根腐病菌、棉花黄萎病菌、番茄青枯病菌、甘蓝黑腐病菌等重要土传病原菌有较强拮抗作用;温室盆栽试验对番茄青枯病表现出较好防效,其中以BOH2和OH11效果较为明显,防效分别为90.9%和86.4%。通过形态观察、生理生化试验和16S rDNA序列分析,确定OH11为产酶溶杆菌,BOH3为荧光假单胞菌,其余5个菌株为不同芽孢杆菌。

关键词：土传病原菌拮抗细菌筛选鉴定

EAsdiA基因的克隆和作为新靶标对梨火疫病菌的检测

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农业生物技术学报 2007年第2期15卷 312-317页

作者：高岩宋俊贤张蕾姜英华胡白石刘凤权许志刚南京农业大学农业部病虫监测与治理重点开放实验室南京农业大学农业部病虫监测与治理重点开放实验室南京210095

基因sdiA属于与群体效应相关的LuxR家族,目前已证实存在于Escherichia coli和Salmonella typhimurium基因组中。本研究从梨火疫病菌(Erwinia amylovora)中克隆到了一个sdiA的同源基因,命名为EAsdiA(GenBank登录号:AY864839),该基因与E.coli和S.typhimurium的sdiA基因在氨基酸水平上分别有45.42%和43.33%的同源性,与其它细菌的luxR同源基因的同源性更低。根据梨火疫病菌EAsdiA和其它病原细菌的luxR基因的序列比对设计了1对特异引物F-EAluxR和R-EAluxR,能够特异地检测梨火疫病菌,检测灵敏度为10个菌体,在含有梨组织浸出液中可检测到102个菌体。本研究首次从梨火疫病菌中克隆sdiA基因并作为新靶标应用于该病菌分子检测。

关键词：群体感应 LuxR 梨火疫病菌分子检测

Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng feng Qichun feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong guo Jingyuan guo Wanlei guo Xinheng guo Yuhang guo Paul Hackspacher Caren Hagner Ran Han Yan Yerevan Physics Institute YerevanArmenia UniversitéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Department of Physics National T

The jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment.

关键词： neutrino oscillation solar neutrino JUNO

Sub-percent precision measurement of neutrino oscillation parameters with JUNO

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Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem 安丰鹏安琪 Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste 白伟东 Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga 蔡浩蔡啸蔡严克蔡志岩 Riccardo Callegari Antonio Cammi Agustin Campeny 曹传亚曹国富曹俊 Rossella Caruso Cédric Cerna Chi Chan 常劲帆 Yun Chang 陈国明陈平平 Po-An Chen 陈少敏 Xurong Chen 陈义学陈羽陈志源陈梓康程捷程雅苹 Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille 邓智邓子艳 Wilfried Depnering Marco Diaz Xuefeng Ding 丁雅韵 Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko 董建蒙 Evgeny Doroshkevich Marcos Dracos Frédéric Druillole 杜然杜书先 Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Donghua Fan 樊磊方建方文兴 Marco Fargetta Dmitry Fedoseev 费政勇 Li-Cheng feng 冯启春 Richard Ford Amélie Fournier 甘浩男高峰 Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar 龚光华宫辉 Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov 顾旻皓谷肖飞古宇关梦云管宇铎 Nunzio Guardone 郭聪郭竞渊郭万磊 Xinheng guo 郭宇航 Paul Hackspacher Caren Hagner 韩然 Yang Han 何苗 Wei He Tobias Heinz Patrick Hellmuth 衡月昆 Rafael Herrera 贺远强侯少静 Yee Hsiung Bei-Zhen hu 胡航 Jianrun hu 胡俊胡守扬胡涛胡宇翔胡焯钧黄桂鸿黄翰雄黄凯旋黄文昊 Xin huang 黄性涛黄永波惠加琪霍雷霍文驹 Cédric huss Safeer hussain Ara Ioannisian Roberto Isocrate Beatrice Jelmini Ignacio Jeria 季筱璐贾慧慧贾俊基蹇司玉蒋荻蒋炜江晓山荆小平 Cécile Jollet Jari Joutsenvaara Leonidas Kalousis Philipp Kampmann 康丽 Rebin Karaparambil Narine Kazarian Amina Khatun Yerevan Physics Institute YerevanArmenia UniversiéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observatory under construction in the south of China.This publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the experiment.The sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite detector.It is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data collection.In the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering hypothesis.The new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO

2007-2008年北京地区25～54岁已婚妇女高危型人乳头状瘤病毒感染的流行病学调查

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中华妇产科杂志 2009年第12期44卷 892-897页

作者：武明辉张淞文张为远周保利谢争王建东冯静王军华蒋京伟朱力黄石全潘静刘新芝张运平赵温李虹罗晓航史坤翀王桂凤付立平李桂香陶惠芬戴春香何瑞霞金蕾刘广美王奎香叶家林刘似英王梅闫学明胡桂玲林如静孙嫦月曾红吴丽荣程亚利首都医科大学附属北京妇产医院保健部 100026 首都医科大学附属北京妇产医院产科 100026 首都医科大学附属北京妇产医院肿瘤科 100026 首都医科大学附属北京妇产医院病理科 100026 北京市海淀区妇幼保健院保健部北京市朝阳区妇幼保健中心保健部北京市丰台区妇幼保健院保健部北京市怀柔区妇幼保健院妇保科北京市延庆县妇幼保健院保健部北京市通州区妇幼保健院妇保科北京市大兴区妇幼保健院妇保科北京市东城区妇幼保健院保健部北京市西城区妇幼保健所妇保科北京市石景山区妇幼保健院妇保科北京市崇文区妇幼保健院保健部北京市宣武区妇幼保健院保健部

目的了解北京地区妇女生殖道高危型人乳头状瘤病毒（HR—HPV）的感染状况及其分布特点，初步探讨HR—HPV感染的相关因素。方法于2007年3月至2008年9月，采用多阶段整群随机抽样的方法，在北京地区抽取12个区县137个社区25～54岁已婚妇女... 详细信息

目的了解北京地区妇女生殖道高危型人乳头状瘤病毒（HR—HPV）的感染状况及其分布特点，初步探讨HR—HPV感染的相关因素。方法于2007年3月至2008年9月，采用多阶段整群随机抽样的方法，在北京地区抽取12个区县137个社区25～54岁已婚妇女6185例进行妇科检佥、宫颈HR—HPV检测及细胞学检查，并进行问卷调查。应用EpiData3．0软件双次录入、审核数据后，应用SPSS15．0软件进行统计学分析。结果（1）北京地区25～54岁已婚妇女生殖道HR—HPV感染率为9．89％。城区、近郊、远郊妇女的HR—HPV感染率分别为9．34％、10．51％和9．51％（P〉0．05）；本市、外地户籍妇女的HR—HPV感染率分别为9．53％和11．30％（P〈0．05）。（2）HR—HPV感染的年龄分布特点：25～44岁年龄段妇女的HR—HPV感染率稳定在10％左右，30～34岁者HR—HPV感染率最高，为11．21％；44岁以上则随着年龄增长感染率逐渐下降，50-54岁降至最低（7．78％）。（3）多元logistic回归分析显爪，家庭人均月收入≥1000元、配偶性伴侣数〉1个者、外地户籍、文化程度为高中及以上者，其感染HR—HPV的可能性大。（4）感染HR—HPV人群的宫颈上皮内瘤变（CIN）患病率明显高于未感染人群（分别为29．76％、3．32％，P〈0．01）。结论（1）北京地区25～54岁已婚妇女牛殖道HR—HPV感染率为9．9％，在地域分布上无差异。（2）北京地区HR—HPV感染的危险人群为家庭经济条件优越者、配偶多个性伴侣者、外地户籍及文化程度较高者。（3）HR—HPV感染是发生CIN及宫颈癌的重要因素，但HR—HPV感染并不等于一定发生CIN和宫颈癌；应对HR—HPV感染者定期随访以了解其感染及宫颈的动态变化。

关键词：乳头状瘤病毒,人乳头状瘤病毒感染子宫颈抽样研究问卷调查流行病学