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Smartphone-assisted electrochemiluminescence imaging test strips towards dual-signal visualized and sensitive monitoring of aflatoxin B1 in corn samples

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Chinese Chemical Letters 2025年第1期36卷 464-468页

作者： Miao-Miao Chen Min-Ling Zhang Xiao Song jun Jiang Xiaoqian Tang qi Zhang Xiuhua Zhang Peiwu Li Key Laboratory of Biology and Genetic Improvement of Oil Crops Ministry of Agriculture and Rural AffairsLaboratory of Risk Assessment for Oilseed Products(Wuhan)Quality Inspection and Test Center for Oilseed ProductsOil Crops Research InstituteChinese Academy of Agricultural SciencesWuhan 430062China Food Safety Research Institute Hubei UniversityWuhan 430062China Hubei Hongshan Laboratory Wuhan 430070China xianghu Laboratory Hangzhou 311231China College of Chemistry and Chemical Engineering Hubei UniversityWuhan 430062China

Aflatoxins B1(AFB1)contamination in agro-food holds great threaten to human and animal *** test strips for rapid AFB1 visualized monitoring remains challenged by improvement of sensitivity and matrix interference *** this case,we developed a portable electrochemiluminescence(ECL)imaging test strip with dual-signal outputs for AFB1 quantification in corn ***@SiO_(2)@Au nanospheres were synthesized for bonding with anti-AFB1 antibody and then colorimetrical signal-reported on test line through the capillary flow at ***,ECL imaging signal of the constructed carbon-ink-based working electrode on polyvinyl chloride substrate of strips was exported under an applied potential of 1.25 *** whole ECL test strips not only endowed convenient colorimetric responses but guaranteed quick-witted ECL image distinguishment even at extremely low AFB1 *** detection limit of this ECL imaging-integrated mode was 10-fold lower than that of only colorimetric ***,satisfactory selectivity,reliability and practicability of the as-proposed ECL test strips were *** work offered a promising platform for on-site,accurate and sensitive detection of pollutants in foods.

关键词： Electrochemiluminescence imaging Test strips Nanomaterials Dual-signal outputs Aflatoxin B1 Food safety

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关于高校多校区办学管理模式的探讨

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安阳大学学报（综合版） 2004年第4期 81-82页

作者：齐献军安阳工学院河南安阳455000

随着高等教育管理体制改革的逐步推进,很多高校都在进行着一校多区的办学实践。多校区办学开拓了新的教育发展空间,弥补了教育资源的不足,增加了高校的竞争优势,解决了一些矛盾,但是也带来了新的问题。因此,探索多校区办学的教学管理模... 详细信息

随着高等教育管理体制改革的逐步推进,很多高校都在进行着一校多区的办学实践。多校区办学开拓了新的教育发展空间,弥补了教育资源的不足,增加了高校的竞争优势,解决了一些矛盾,但是也带来了新的问题。因此,探索多校区办学的教学管理模式是目前相关高校急需解决的课题。

关键词：多校区办学高校教学管理模式办学实践高等教育管理教育资源教育发展竞争优势增加体制改革

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美国高校激励机制对我国高校建设的启示

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安阳工学院学报 2006年第3期5卷 134-136页

作者：齐献军安阳工学院河南安阳455000

中美两国虽然在国情上存在很大的差别,但从人性的角度来讲,两国的高校教师激励机制又存在着相通相近的地方。对于我国高校教师激励机制的建设与完善,美国现行的诸多做法值得我们借鉴和学习。

关键词：高校激励机制启示

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Plasma metabolomics combined with mass spectrometry imaging reveals crosstalk between tumor and plasma in gastric cancer genesis and metastasis

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Chinese Chemical Letters 2025年第1期36卷 506-512页

作者： Yanhua Chen xian Ding jun Zhou Zhaoying Wang Yunhai Bo Ying Hu qingce Zang Jing Xu Ruiping Zhang Jiuming He Fen Yang Zeper Abliz Key Laboratory of Mass Spectrometry Imaging and Metabolomics(State Ethnic Affairs Commission) Center for Imaging and Systems BiologyCollege of Life and Environmental SciencesMinzu University of ChinaBeijing 100081China State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100050China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Center of Drug Clinical TrialPeking University Cancer Hospital and InstituteBeijing 100142China Beijing Engineering Research Center of Food Environment and Public Health Minzu University of ChinaBeijing 100081China Key laboratory of Ethnomedicine of Ministry of Education School of PharmacyMinzu University of ChinaBeijing 100081China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Department of BioBankPeking University Cancer Hospital and InstituteBeijing 100142China Pharmacy Department of Beijing Chao–Yang Hospital Capital Medical UniversityBeijing 100020China

Gastric Carcinoma(GC)is a highly fatal malignant tumor with a poor *** elevated mortality rates are primarily due to its proclivity for late-stage *** the metabolic interactions between tumor microenvironment and the systemic bloodstream could help to clearly understand the mechanisms and identify precise biomarkers of tumor growth,proliferation,and *** this study,an integrative approach that combines plasma metabolomics with mass spectrometry imaging of tumor tissue was developed to investigate the global metabolic landscape of GC tumorigenesis and *** results showed that the oxidized glutathione to glutathione ratio(GSSH/GSH)became increased in non-distal metastatic GC(M0),which means an accumulation of oxidative stress in tumor ***,it was found that the peroxidation of polyunsaturated fatty acids,such as 9,10-EpOMe,9-HOTrE,etc.,were accelerated in both plasma and tumor tissues of distal metastatic GC(M1).These changes were further confirmed the potential effect of CYP2E1 and GGT1 in metastatic potential of GC by mass spectrometry imaging(MSI)and immunohistochemistry(IHC).Collectively,our findings reveal the integrated multidimensional metabolomics approach is a clinical useful method to unravel the bloodtumor metabolic crosstalk,illuminate reprogrammed metabolic networks,and provide reliable circulating biomarkers.

关键词： Metabolomics Spatial-resolved metabolomics Gastric cancer Blood-tumor metabolic crosstalk Lipid peroxidation

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Novel photoresponsive dinuclear nickel catalysts for ethylene (co)polymerization

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Science China Chemistry 2025年第2期68卷 714-722页

作者： Chenlong Nan Tong Pang Jiaxing Zhao Lijia Fan Chen Zou Xin-qi Hao Mao-Ping Song jun-Fang Gong Changle Chen Hui Jiang College of Chemistry Pingyuan LaboratoryZhengzhou UniversityZhengzhou 450001China CAS Key Laboratory of Soft Matter Chemistry Department of Polymer Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China

Compared with the conventional strategies of electronic and/or steric perturbation,catalytic olefin polymerization modulated by light irradiation or metal-metal cooperativity effect is a fascinating challenge that attracts considerable attention in the academic *** this context,we design a strategy that could employ both effects to influence the polymerization *** dinuclear salicylaldimine andα-imino-ketone nickel complexes bearing a stiff-stilbene bridge were prepared,which could transfer between(E)-isomers and(Z)-isomers under ultraviolet *** isomerization can tune the electronic,steric and metal-metal cooperativity effects of the nickel *** this way,the catalytic activity,as well as polymer microstructures including molecular weight and branching density can be modulated in ethylene polymerization and copolymerization *** strategy is generally applicable to other olefin polymerization catalytic systems and other types of transition metal mediated catalysis.

关键词： photoresponsive dinuclear catalyst nickel(II) polar monomer olefin copolymerization

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Bone marrow mesenchymal stem cells promote uterine healing by activating the PI3K/AKT pathway and modulating inflammation in rat models

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World Journal of Stem Cells 2025年第1期17卷 22-39页

作者： Jing Yang jun Yuan Yan-qing Wen Li Wu Jiu-Jiang Liao Hong-Bo qi Women and Children’s Hospital of Chongqing Medical University Chongqing 401147China Chongqing Key Laboratory of Maternal and Fetal Medicine Chongqing Medical UniversityChongqing 400016China Obstetrics and Gynecology Guizhou Provincial People’s HospitalGuiyang 557300Guizhou ProvinceChina Research Laboratory of Reproduction and Development of Chinese Ministry of Education Chongqing Medical UniversityChongqing 400016China

BACKGROUND Uterine injury can cause uterine scarring,leading to a series of complications that threaten women’s *** healing is a complex process,and there are currently no effective *** our previous studies have shown that bone marrow mesenchymal stem cells(BMSCs)promote uterine damage repair,the underlying mechanisms remain ***,exploring the specific regulatory roles of BMSCs in uterine injury treatment is crucial for further understanding their functions and enhancing therapeutic *** To investigate the underlying mechanism by which BMSCs promote the process of uterine *** In in vivo experiments,we established a model of full-thickness uterine injury and injected BMSCs into the uterine *** sequencing was per-formed to determine the enrichment of differentially expressed genes at the wound *** in vitro experiments,we isolated rat uterine smooth muscle cells(USMCs)and cocultured them with BMSCs to observe the interaction between BMSCs and USMCs in the *** We found that the differentially expressed genes were mainly related to cell growth,tissue repair,and angiogenesis,while the phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT)pathway was highly *** reverse-transcription polymerase chain reaction was used to validate differentially expressed genes,and the results demonstrated that BMSCs can upregulate genes related to regeneration and downregulate genes related to *** BMSCs promoted the migration and proliferation of USMCs,and the USMC microenvironment promoted the myogenic differentiation of ***,we validated the PI3K/AKT pathway in tissues and cells and showed that BMSCs activate the PI3K/AKT pathway to promote the regeneration of uterine smooth muscle both in vivo and in *** BMSCs upregulated uterine wound regeneration and anti-inflammatory factors and enhanced uterine smooth muscle proliferation throu

关键词： Uterine injury Bone marrow mesenchymal stem cells Uterine smooth muscle cells Phosphoinositide 3-kinase/protein kinase B pathway Cell-cell interactions Cell proliferation Immune regulation Wound regeneration

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Accelerating homogenization kinetics and enhancing hot-workability of as-cast nickel-based superalloy via prior hot-deformation

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Journal of Iron and Steel Research International 2025年第1期32卷 215-226页

作者： Jia-jun Chen Yang Zhou Hao-ran Han xian-guang Zhang Goro Miyamoto Ping-mei Tang Dong-ping Xiao Jian-hui Fu Peng Shi Yi-wu Pei Jian Zhang State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Chengdu Advanced Metal Materials Industrial Technology Institute Co. Ltd.Chengdu 610300SichuanChina Institute for Materials Research Tohoku UniversitySendai 980-8577Aoba-KuJapan

Enhancing homogenization efficiency and hot-workability is the key issue for wrought superalloys in the industry.A novel approach for simultaneous accelerating the homogenization kinetics and improving hot-workability via a simple way of prior hot-deformation was proposed,which was not widely accepted for wrought *** homogenization efficiency is increased by 40%-70%via performing 10%-20%prior *** theoretical and experimental analyses revealed that the increment in homogenization efficiency is mainly attributed to the decrease in interdendritic-segregation spacing,and thus the necessary diffusion distance,rather than that of *** addition,dynamic and static recrystallizations occurred during the prior hot-deformation and diffusion-annealing processes,and the grains were significantly refined even after the ***,the size of the precipitates was refined as *** enhanced the hot-workability of the homogenized ingot for the subsequent cogging process.

关键词： Nickel-based superalloy Homogenization kinetics Prior hot-deformation Grain size Hot workability

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从PC搜索到手机搜索的用户转移行为意向研究

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情报科学 2018年第7期36卷 71-77页

作者：陈明红温杰尧曾庆彬漆贤军中山大学资讯管理学院广东广州510006

【目的/意义】在移动互联网环境下,越来越多人使用手机搜索信息和服务,不少用户正在从电脑搜索向手机搜索转移,探讨用户转移意向及影响成为当前研究的重要议题。【方法/过程】为探究用户从电脑搜索向手机搜索转移的关键影响因素和作用机... 详细信息

【目的/意义】在移动互联网环境下,越来越多人使用手机搜索信息和服务,不少用户正在从电脑搜索向手机搜索转移,探讨用户转移意向及影响成为当前研究的重要议题。【方法/过程】为探究用户从电脑搜索向手机搜索转移的关键影响因素和作用机制,本文以双系统认知理论为基础,构建用户搜索行为转移意向理论模型和相关假设。通过网络问卷和纸质问卷共回收375份有效样本,利用偏最小二乘法进行数据分析。【结果/结论】结果表明:感知移动性、感知场景性和低转移成本三个分析因素均对转移意向具有正向影响;直觉因素中的感知流行性对转移意向具有显著的正向影响,而电脑搜索习惯具有显著的负向影响;转移情境具有正向影响。最后,针对手机搜索服务提升和用户搜索行为优化提出有效措施。

关键词：手机搜索转移意向双系统分析因素直觉因素

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Carboniferous-Early Permian heterogeneous distribution of porous carbonate reservoirs in the Central Uplift of the South Yellow Sea Basin and its hydrocarbon potential analysis

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China Geology 2025年第1期8卷 58-76页

作者： Shu-yu Wu jun Liu Jian-wen Chen qi-liang Sun Yin-guo Zhang Jie Liang Yong-cai Feng School of Engineering China University of GeoscienceWuhan 430074China Yantai Center of Coastal Zone Geological Survey China Geological SurveyMinistry of Natural ResourcesYantai 264001China Key Laboratory of Submarine Geosicences Ministry of Natural ResourcesHangzhou 310012China Chinese Academy of Geological Sciences China Geological SurveyMinistry of Natural ResourcesBeijing 100037China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266061China The Key Laboratory of Gas Hydrate Ministry of Natural ResourcesQingdao Institute of Marine GeologyChina Geological SurveyMinistry of Natural ResourcesQingdao 266071China College of Marine Science and Technology China University of GeoscienceWuhan 430074China

Mesozoic-Palaeozoic marine carbonate rocks are crucial hydrocarbon reservoirs in the Central Uplift area of the South Yellow Sea Basin(SYSB).Due to the scarcity of boreholes and the significant heterogeneity of carbonate reservoirs,the distribution of porous carbonate reservoirs and their related key controlling factors remain *** this study,factors affecting the distribution of porous Carboniferous-Early Permian carbonate reservoirs in the SYSB were investigated through seismic inversion and isotope *** log-seismic characteristics of porous carbonate reservoirs,sensitive lithology parameters,and physical property parameters were extracted and *** pre-stack simultaneous inversion technique was applied to predict the lithology and physical properties of porous carbonate ***,the sedimentary of carbonate was analyzed using isotopes of carbon,oxygen,and *** results show that porous carbonate reservoirs are mainly developed in the open platform sediments with porosities of 3%-5%and are mainly distributed in the paleo-highland(Huanglong Formation and Chuanshan Formation)and the slope of paleo-highland(Hezhou Formation).The porous carbonate reservoirs of the qixia Formation are only locally *** addition,the negativeδ13C excursions indicate a warm and humid tropical climate with three sea-level fluctuations in the study area from the Carboniferous to Early *** favorable conditions for developing porous carbonate rocks include the sedimentary environment and diagenetic *** primary pore tends to form in high-energy environments of the paleo-highland,and the secondary pore is increased by dissolution during the syngenetic or quasi-syngenetic *** to the hydrocarbon potential analysis,the Late Ordovician Wufeng Formation and Lower Silurian Gaojiabian Formation are the source rocks in the high-maturity-over-maturity stage,the Carboniferous-Lower Permian carbonate is the good reservoirs,and th

关键词： Sedimentary Heterogeneous porous carbonate reservoirs C-H-Sr isotope analysis Carboniferous-Early Permian Chuanshan Formation Huanglong Formation Pre-stack simultaneous inversion technique Oil-gas exploration engineering Hydrocarbon accumulation Hydrocarbon potential Central Uplift of the South Yellow Sea Basin

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全自动灯检机研究和开发

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机电工程技术 2011年第12期40卷 1-5页

作者：齐显军刘焕军张祺李军珐玛珈(广州)包装设备有限公司广东广州510730 广东工业大学广东广州510006

提出了一种基于机器视觉的全自动灯检测机。这种灯检机采用多工位设计,能对药液及其包装瓶进行多项检测。设计了专门装置采集瓶内旋转液体的序列图像,运用图像融合和运动分析的方法对包装瓶和液体图像进行识别,能保证全面准确地检测产... 详细信息

提出了一种基于机器视觉的全自动灯检测机。这种灯检机采用多工位设计,能对药液及其包装瓶进行多项检测。设计了专门装置采集瓶内旋转液体的序列图像,运用图像融合和运动分析的方法对包装瓶和液体图像进行识别,能保证全面准确地检测产品质量。

关键词：自动检测机器视觉运动分析

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