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Staged dendrite suppression for high safe and stable lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 674-683页

作者： Jun Jiang Zhenjie Lu Yanwen Ding Shujun Liu Zhijie qi Tian Tang Yunfan Zhang Zhiyuan Ma Jingwen Sun Liang Xue Wenyao Zhang Pan Xiong Xin Wang Junwu Zhu Yongsheng Fu Key Laboratory for Soft Chemistry and Functional Materials of Ministry of Education Nanjing University of Science and Technology Jiangsu Pylon Battery Co.Ltd

The unavoidable dendrite growth and shuttle effect have long been stranglehold challenges limiting the safety and practicality of lithium-sulfur ***,we propose a dual-action strategy to address the lithium dendrite issue in stages by constructing a multifunctional surface-negatively-charged nanodiamond layer with high ductility and robust puncture resistance on polypropylene （PP） *** uniformly loaded compact negative layer can not only significantly enhance electron transmission efficiency and promote uniform lithium deposition,but also reduce the formation of dendrite during early deposition *** importantly,under the strong puncture stress encountered during the deterioration of lithium dendrite growth under limiting current,the high ductility and robust puncture resistance（145.88 MPa） of as-obtained nanodiamond layer can effectively prevent short circuits caused by unavoidable lithium *** Li||Li symmetrical cells assembled with nanodiamond layer modified PP demonstrated a stable cycle of over 1000 h at 2 mA cm-2with a polarization voltage of only 29.3 ***,the negative charged layer serves as a physical barrier blocking lithium polysulfide ions,effectively mitigating capacity *** improved cells achieved a capacity decay of only 0.042%per cycle after 700 cycles at 3 C,demonstrating effective suppression of dendrite growth and capacity attenuation,showing promising prospect.

关键词： Lithium-sulfur batteries Staged dendrite suppression Shuttle effect Surface-negatively-charged nanodiamond

Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles

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Neural Regeneration Research 2025年第4期20卷 1124-1134页

作者： Yanting Liu Wei Huang Jiayi Wen Xin Xiong Ting Xu qi Wang Xiusheng Chen Xianxian Zhao Shihua Li Xiaojiang Li Weili Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong-Hongkong-Macao CNS Regeneration Institute of Jinan UniversityJinan UniversityGuangzhouGuangdong ProvinceChina

The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal ***,it remains largely unclear how PINK1 and Parkin are expressed in mammalian *** has been difficult to address because of the intrinsically low levels of PINK1 and undetectable levels of phosphorylated Parkin in small *** this issue is critical for elucidating the in vivo roles of PINK1 and ***,we showed that the PINK1 kinase is selectively expressed as a truncated form(PINK1–55)in the primate *** the present study,we used multiple antibodies,including our recently developed monoclonal anti-PINK1,to validate the selective expression of PINK1 in the primate *** found that PINK1 was stably expressed in the monkey brain at postnatal and adulthood stages,which is consistent with the findings that depleting PINK1 can cause neuronal loss in developing and adult monkey ***1 was enriched in the membrane-bound fractionations,whereas Parkin was soluble with a distinguishable *** double staining experiments showed that PINK1 and Parkin did not colocalize under physiological conditions in cultured monkey astrocytes,though they did colocalize on mitochondria when the cells were exposed to mitochondrial *** findings suggest that PINK1 and Parkin may have distinct roles beyond their well-known function in mitophagy during mitochondrial damage.

关键词： neurodegeneration Parkin Parkinson’s disease PINK1 subcellular distribution

Endoplasmic reticulum stress and autophagy in cerebral ischemia/reperfusion injury:PERK as a potential target for intervention

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Neural Regeneration Research 2025年第5期20卷 1455-1466页

作者： Ju Zheng Yixin Li Ting Zhang Yanlin Fu Peiyan Long Xiao Gao Zhengwei Wang Zhizhong Guan Xiaolan qi Wei Hong Yan Xiao Key Laboratory of Endemic and Ethnic Diseases Ministry of Education&Key Laboratory of Medical Molecular Biology of Guizhou ProvinceGuizhou Medical UniversityGuiyangGuizhou ProvinceChina Guizhou Center for Disease Control and Prevention GuiyangGuizhou ProvinceChina Department of Histology and Embryology Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry GuiyangGuizhou ProvinceChina

Several studies have shown that activation of unfolded protein response and endoplasmic reticulum(ER)stress plays a crucial role in severe cerebral ischemia/reperfusion *** occurs within hours after cerebral ischemia,but the relationship between ER stress and autophagy remains *** this study,we established experimental models using oxygen-glucose deprivation/reoxygenation in PC12 cells and primary neurons to simulate cerebral ischemia/reperfusion *** found that prolongation of oxygen-glucose deprivation activated the ER stress pathway protein kinase-like endoplasmic reticulum kinase(PERK)/eukaryotic translation initiation factor 2 subunit alpha(e IF2α)-activating transcription factor 4(ATF4)-C/EBP homologous protein(CHOP),increased neuronal apoptosis,and induced ***,inhibition of ER stress using inhibitors or by si RNA knockdown of the PERK gene significantly attenuated excessive autophagy and neuronal apoptosis,indicating an interaction between autophagy and ER stress and suggesting PERK as an essential target for regulating *** autophagy with chloroquine exacerbated ER stress-induced apoptosis,indicating that normal levels of autophagy play a protective role in neuronal injury following cerebral ischemia/reperfusion *** from this study indicate that cerebral ischemia/reperfusion injury can trigger neuronal ER stress and promote autophagy,and suggest that PERK is a possible target for inhibiting excessive autophagy in cerebral ischemia/reperfusion injury.

关键词： apoptosis ATF4 autophagy C/EBP homologous protein cerebral ischemia/reperfusion injury eIF2α endoplasmic reticulum stress PERK

Vegetation characteristics and soil properties of artificially remediated grasslands:The case study of the Shimenhe mining area in qilian Mountains,northwest China

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Research in Cold and Arid Regions 2024年第4期16卷 190-200页

作者： XiaoMei Yang qi Feng Meng Zhu Key Laboratory of Ecohydrology of Inland River Basin Alax Desert Eco-hydrology Experimental Research StationQilian Mountains Eco-Environment Research Center in Gansu ProvinceNorthwest Institute of Eco-Environment and ResourcesChinese Academy of Sciences(CAS)LanzhouGansu 730000China

The mining of limestone mines plays a crucial role in societal and economic ***,mining activities have led to destructive variations in grassland ecology and soil,causing numerous environmental problems,and effective artificial restoration measures have been used to restore grasslands in the Shimenhe mining areas to different *** this study,we investigated,examined and analyzed plant community structure and its correlation with soil properties across varying degrees of alpine grassland restoration in qilian Mountains Shimenhe restoration mines using the sample method,and studied the changes in species diversity using five diversity indexes(Simpson index,Shannon index,Margalef index,Dominance index and Evenness index).This study showed that the plant community characteristics with high recovered degree(HRD)> middle recovered degree(MRD)> low recovered degree(LRD)> very low recovered degree(VLRD),11 plant genera comprising 11 species across 10 families were *** families with robust ecological adaptability included Leguminosae,Rosaceae,Gramineae,Asteraceae,and *** highest Simpson,Shannon,Margalef and Evenness index of HRD grassland community species were 0.82,1.96,1.66 and 0.89,*** highest Dominance index of VLRD grassland community species was 0.34,which required several restoration methods such as spraying and *** pH and EC tended to decrease with increasing restoration,SOC,SMC,TP,AP,NH4-N,TN,AN and NO3-N tended to increase and the content of soil environmental factors contributed to vegetation growth across various restoration levels the mine *** conclusion,our study indicated that the community structure gradually diversified and soil properties changed positively with the increase of restoration degrees in the qilian Mountains Shimenhe mine,and the best results of HRD restoration were *** study provides the theoretical basis for the restoration and conservation of grassland

关键词： Alpine mining area grassland Grassland ecosystem Mine restoration Plant characteristics Soil properties qilian mountains

乌玛高速沙漠段风沙环境特征及格状沙丘移动规律

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水土保持研究 2025年第1期32卷 160-171页

作者：李良英王振强王旭辛国伟李琦吕乐乐兰州交通大学土木工程学院

[目的]沙丘移动与风沙环境特征和沙丘形态具有直接关系，探究多种因素作用下的格状沙丘移动规律，能为沙区公路风沙防治提供科学依据。[方法]以乌玛高速沙漠段格状沙丘为研究对象，基于当地气象数据、Google Earth卫星影像，研究了2019... 详细信息

[目的]沙丘移动与风沙环境特征和沙丘形态具有直接关系，探究多种因素作用下的格状沙丘移动规律，能为沙区公路风沙防治提供科学依据。[方法]以乌玛高速沙漠段格状沙丘为研究对象，基于当地气象数据、Google Earth卫星影像，研究了2019—2021年乌玛高速沙漠段K167+300,K172+300,K177+300里程处风沙环境及格状沙丘的形态演变和移动规律。[结果](1)研究区年平均起沙风速介于6.07～6.84 m/s,春夏为主要输沙季节，主风向为西北风，次风向为东南风；年输沙势介于31.77～38.89 VU,方向变率指数(RDP/DP)介于0.73～0.78,属于低风能环境、中变率风况。(2)研究区自东北向西南方向，格状沙丘主梁向东偏移，副梁向南偏移，主副梁走向几乎保持垂直，沙丘形态整体上变化较小；格状沙丘的主副梁长度、主副梁间距、沙丘高度均呈现出增加的趋势，主副梁长度增长率、主副梁偏移率呈减小趋势。(3)沙丘移动方向介于140.43°～152.64°,与年RDD变化基本一致，即向东南偏移；沙丘平均高度介于5.24～8.31 m,沙丘移动速率介于2.31～2.86 m/a,两者表现为负相关关系。(4)输沙势、年均温度与沙丘移动速率为正相关关系，相较而言，年均温度对沙丘移动速率的影响更为显著；年均降水量、植被覆盖度与沙丘移动速率为负相关关系，其中年均降水量对移动速率的影响尤为重要。[结论]格状沙丘的移动与当地风况、降水量、温度、植被覆盖度及沙丘自身形态息息相关，其中输沙势及温度增加会加速沙丘前移，不利于对风沙的防治，而提高降水量及植被覆盖度，对防治沙丘移动引起的公路风沙灾害具有积极作用。

关键词：格状沙丘输沙势空间插值沙丘移动形态演变

Effects of green energy development on population growth and employment:Evidence from shale gas exploitation in Chongqing,China

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Petroleum Science 2021年第5期18卷 1578-1588页

作者： Hui Hu Yu-qi Zhu Si-Yue Li Zheng Li Economic Development Research Centre Wuhan UniversityWuhan430072HubeiChina School of Economics&Management Wuhan UniversityWuhan430070HubeiChina

With the maturity of horizontal drilling and hydraulic fracturing technologies,countries rich in shale gas have begun to promote the development of the shale gas *** impact of the booming shale gas industry on the regional economy has also become a main *** gas’exploration and extraction may have positive spillover effects on other sectors,resulting in population growth and job ***,negative spillover effects can occur through rising local goods prices and its adverse effects on the local quality of life,which in turn could harm population growth and *** using the synthetic control method,we investigates the shale gas fields in Chongqing to reveal the relationship between population growth,employment and shale gas development in Fuling,Nanchuan and Wulong *** results indicate that due to the development of the shale gas industry,the number of urban non-private sector employees in three districts and counties has *** 2017 to 2018,this decline had gradually weakened and the population growth had been negatively affected.

关键词： Shale gas exploitation Synthetic control method Population Employment

Response mechanism of soil microorganisms to simulated precipitation in the source wetland of qinghai Lake

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Ecological Processes 2024年第2期13卷 61-71页

作者： Xinye Wang Ni Zhang Kelong Chen Tiexi Chen Desheng qi Yuanxi Ma School of Geographical Sciences Qinghai Normal University National Positioning Observation and Research Station of qinghai Lake Wetland Ecosystem in qinghai National Forestry and Grassland Administration Key Laboratory of Tibetan Plateau Land Surface Processes and Ecological Conservation(Ministry of Education) Qinghai Normal University School of Geographical Sciences Nanjing University of Information Science and Technology qinghai Provincial land spatial Planning Research Institute

Background Changes in precipitation patterns crucially impact soil microbial communities, and the ecosystem in qinghai-Tibet Plateau(QTP) is highly vulnerable to climate change. However, we do not fully understand how soil microbial communities in the source wetlands of QTP respond to changes in precipitation. In this study, we employed advanced techniques such as high-throughput sequencing and metabolomics to investigate how soil microbial communities in a source wetland of qinghai Lake respond to changes in precipitation after quadrennial precipitation *** Our findings showed that the predominant microbiota in the source wetland was Proteobacteria. Interestingly, alterations in precipitation levels, whether increased or reduced, did not significantly impact the diversity or functional groups of the microbial community. However, the structure of the microbial community did respond notably to changes in precipitation, leading to shifts in the relative abundance of Spirochaetes and Treponema. A notable finding was that reduced precipitation levels(– 25% and-50%) and mild increases in precipitation(25%) within the region contributed to increased soil carbon content. However, this effect ceased to manifest when precipitation increased by 50%. Additionally, the reduction in precipitation prompted the release of soil metabolites like syringic acid and aldosterone, while enhanced precipitation resulted in a decrease in aldosterone *** Precipitation changes altered the relative abundance of soil microbial communities and metabolites, which was conducive to increasing carbon storage in this alpine wetland.

关键词： qinghai-Tibet Plateau Climate change Precipitation gradient Carbon and nitrogen cycles LC/MS

基于qi算法的Delaunay三角网逐点插入法

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遥感信息 2011年第1期33卷 92-96页

作者：杨琦明周晓光张剑王美玲周辉中南大学测绘与国土信息工程系长沙410083

Delaunay三角网在很多领域都有着广泛的应用,快速高效地生成Delaunay三角网十分重要。逐点插入法是构建Delaunay三角网中使用最广泛的方法之一。本文深入研究了使用逐点插入法构建不带约束条件Delaunay三角网的过程。在使用该方法生成De... 详细信息

Delaunay三角网在很多领域都有着广泛的应用,快速高效地生成Delaunay三角网十分重要。逐点插入法是构建Delaunay三角网中使用最广泛的方法之一。本文深入研究了使用逐点插入法构建不带约束条件Delaunay三角网的过程。在使用该方法生成Delaunay三角网中建立结点拓扑关系这一影响构网效率的关键步骤中引入了qi算法,简化了该方法生成Delaunay三角网的复杂度。然后在向Delaunay三角网内插入约束边的过程中,再次引入qi算法,从而提高了构网的效率。为了验证上述模型,我们在Microsoft Visual Studio 2005开发环境下,以C#为开发工具,采用底层开发模式实现了改进的逐点插入法,实验证明引入qi算法能够提高逐点插入法Delaunay三角网构建及插入约束边的效率。

关键词： Delaunay三角网拓扑关系 qi算法效率

Research Progress of qiweibaizhu Powder in Treating Digestive System Diseases

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World Journal of Traditional Chinese Medicine 2021年第4期7卷 391-396页

作者： Shi-qi Liu Ji Li College of Basic Medical Sciences Heilongjiang University of Chinese MedicineHarbinChina

Diarrhea is a common clinical problem that can lead to health complications,including *** is the second-most common cause of death in *** World Health Organization introduced a program to encourage the development and use of traditional herbal medicines in the treatment of *** Powder(QWBZP)is a well-known pediatric prescription in China that is commonly used to treat digestive system diseases,such as diarrhea,which is also a type of syndrome in traditional Chinese *** studies have examined the clinical effects and mechanisms of QWBZP,and innovative and improved formulations have been *** studies on the effects of QWBZP on diarrhea caused by human rotavirus,antibiotic-associated diarrhea,and mesenteric lymphadenitis in experimental models and clinical trials with diarrhea patients have been *** conducted a literature search of several databases,including PubMed,China National Knowledge Infrastructure,Chongqing VIP Information Co.,Ltd.,and Wanfang.A short background of the QWBZP is also *** collective findings highlight the curative effects of QWBZP on diarrhea caused by viral infection,antibiotic use,and mesenteric ***,QWBZP can regulate the balance of the gastrointestinal microbiota and protect and repair the intestinal mucosal *** review will provide a reference for further studies on QWBZP.

关键词： Antibiotic-associated diarrhea intestinal microbiota mesenteric lymphadenitis spleen deficiency viral diarrhea