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Patch testing and cross sensitivity study of adverse cutaneous drug reactions due to anticonvulsants: A preliminary report

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World Journal of Methodology 2017年第1期7卷 25-32页

作者： TN shiny Vikram K Mahajan Karaninder s Mehta pushpinder s chauhan Ritu Rawat Rajni sharma Department of Der-matology Venereology and LeprosyDr.R.P.Govt. Medical College

AIM To evaluate the utility of patch test and cross-sensitivity patterns in patients with adverse cutaneous drug reactions(ACDR) from common anticonvulsants. METHODs Twenty-four(M:F = 13:11) patients aged 18-75 years with ACDR from anticonvulsants were patch tested 3-27 mo after complete recovery using carbamazepine, phenytoin, phenobarbitone, lamotrigine, and sodium valproate in 10%, 20% and 30% conc. in pet. after informed consent. Positive reactions persisting on D3 and D4 were considered significant. REsULTs Clinical patterns were exanthematous drug rash with or without systemic involvement(DREss) in 18(75%), stevens-Johnsons syndrome/toxic epidermal necrolysis(sJs/TEN) overlap and TEN in 2(8.3%) patients each, sJs and lichenoid drug eruption in 1(4.2%) patient each, respectively. The implicated drugs were phenytoin in 14(58.3%), carbamazepine in 9(37.5%), phenobarbitone in 2(8.3%), and lamotrigine in 1(4.7%) patients,respectively. Twelve(50%) patients elicited positive reactions to implicated drugs; carbamazepine in 6(50%), phenytoin alone in 4(33.3%), phenobarbitone alone in 1(8.3%), and both phenytoin and phenobarbitone in 1(8.33%) patients, respectively. Cross-reactions occurred in 11(92%) patients. six patients with carbamazepine positive patch test reaction showed cross sensitivity with phenobarbitone, sodium valproate and/or lamotrigine. Three(75%) patients among positive phenytoin patch test reactions had cross reactions with phenobarbitone, lamotrigine, and/or valproate. CONCLUsION Carbamazepine remains the commonest anticonvulsant causing ACDRs and cross-reactions with other anticonvulsants are possible. Drug patch testing appears useful in DREss for drug imputability and cross-reactions established clinically.

关键词： Anticonvulsant hypersensitivity syndrome Carbamazepine sodium valproate Drug rash with eosinophilia with or without systemic involvement Drug patch test Lamotrigine Phenobarbitone Phenytoin stevens-Johnsons syndrome Toxic epidermal necrolysis

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A comprehensive investigation on nonlinear vibration and bending characteristics of bio-inspired helicoidal laminated composite structures

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 81-100页

作者： s.sAURABH R.KIRAN D.sINGH R.VAIsH V.s.chauhan school of Mechanical and Materials Engineering Indian Institute of Technology Mandi

Bio-inspired helicoidal composite laminates, inspired by the intricate helical structures found in nature, present a promising frontier for enhancing the mechanical properties of structural designs. Hence, this study provides a comprehensive investigation into the nonlinear free vibration and nonlinear bending behavior of bio-inspired composite plates. The inverse hyperbolic shear deformation theory(IHsDT) of plates is employed to characterize the displacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is modeled using the C0finite element method(FEM), and an in-house code is developed in the MATLAB environment to solve it numerically. Various helicoidal layup configurations including helicoidal recursive(HR), helicoidal exponential(HE), helicoidal semi-circular(Hs), linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup sequences and quasi-isotropic configurations are studied. The model is validated, and parametric studies are conducted. These studies investigate the effects of layup configurations, side-to-thickness ratio, modulus ratios, boundary conditions, and loading conditions at different load amplitudes on the nonlinear vibration and nonlinear bending behaviors of bio-inspired composite plates. The results show that the laminate sequence exerts a substantial impact on both nonlinear natural frequencies and nonlinear bending behaviors. Moreover, this influence varies across different side-to-thickness ratios and boundary conditions of the bio-inspired composite plate.

关键词： finite element method (FEM) nonlinear Green-Lagrange inverse hyperbolic shear deformation theory (IHsDT) bio-inspired composite plate helicoidal O322

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some new distance measures for type-2 fuzzy sets and distance measure based ranking for group decision making problems

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Frontiers of Computer science 2014年第5期8卷 741-752页

作者： pushpinder sINGH Department of Computer science Palacky University Olomouc CZ-77146 Czech Republic

In this paper, we propose some distance measures between type-2 fuzzy sets, and also a new family of utmost distance measures are presented. several properties of differ- ent proposed distance measures have been introduced. Also, we have introduced a new ranking method for the ordering of type-2 fuzzy sets based on the proposed distance measure. The proposed ranking method satisfies the reasonable prop- erties for the ordering of fuzzy quantities. some properties such as robustness, order relation have been presented. Lim- itations of existing ranking methods have been studied. Fur- ther for practical use, a new method for selecting the best alternative, for group decision making problems is proposed. This method is illustrated with a numerical example.

关键词： fuzzy sets type-2 fuzzy sets distance measures,ranking function group decision making problems

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Temperature-dependent aggregation of bio-surfactants in aqueous solutions of galactose and lactose:Volumetric and viscometric approach

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Chinese Journal of Chemical Engineering 2018年第5期26卷 1119-1131页

作者： s.chauhan Vivek sharma Maninder Kaur Poonam Chaudhary Department of chemistry Himachal Pradesh University

Modulation in the aggregation behavior of bio-surfactants （bile salts）, sodium cholate （NaC） and sodium deoxycholate （NaDC） in aqueous solutions of carbohydrates （galactose and lactose） have been investigated by measuring the density （ρ）, speed of sound （u） and viscosity （η） of the mixtures at different temperatures 293.15, 298.15, 303.15, 308.15 and 313.15 K. The density and speed of sound data have been used to calculate various volumetric and compressibility parameters such as apparent molar volume （Vφ）, isentropic compressibil- ity （κs）, apparent molar adiabatic compression （κs,φ） to get a better insight into the micellization mechanism of bile salts. Further, the viscosity data have been studied in the light of relative viscosity （ηr） and viscous relaxation time （τ）. some derived parameters such as free volume （νf）, internal pressure （πi） and molar cohesive energy （MCE） of NaC and NaDC in aqueous solution of saccharides have also been calculated from viscosity data in con- junction with density and speed of sound values. All the calculated and derived parameters provide qualitative information regarding the nature of interactions i.e. solute-solute, solute-solvent and solvent-solvent in the solution.

关键词： Density speed of sound Apparent molar volumelsentropic compressibility Viscosity Relative viscosity

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Preparation, characterization and luminescence behavior of some samarium complexes

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Rare Metals 2021年第9期40卷 2618-2626页

作者： Archana chauhan Ritu Langyan Department of Chemistry Kurukshetra UniversityKurukshetra 136119India

The synthesis of luminescent complexes of sm(III) with the general formula [sm(L)_(3)·(X)] was done in powder form. In the formula, L is 6-methyl-4-oxo-4 H-1-benzopyran-3-carboxaldehyde and X represents 2H_(2)O(C1), 1,10-phenanthroline(C2), 2,20-bipyridine(C3);bathophenanthroline(C4) and neocuproine(C5). The complexes were characterized by using various analytical and spectroscopic tools like elemental analysis, electrospray ionization mass spectrometry(EsI–Ms+), Fourier transform infrared spectroscopy(FTIR), ultraviolet–visible(UV–Vis) spectroscopy, thermo-gravimetric analysis/differential thermal gravimetric analysis(TGA/DTG), field emission scanning electron microscopy(FEsEM), powder X-ray diffraction(XRD), and photoluminescence(PL)studies. TGA/DTG showed high thermal stability of synthesized complexes. Powder XRD depicts that the average particle size lies in the nano-range. On monitoring at the excitation wavelength of 370 nm, the complexes display characteristic luminescence peaks of sm(III) at ~564,~600 and ~647 nm assigned to^(4)G_(5/2)→^(6)H_(5/2),^(4)G_(5/2)→^(6)H_(7/2), and ^(4)G_(5/2)→6H9/2 transitions, respectively, with the most intense transition at ~600(orange emission) and~647 nm(bright red emission) in liquid and powder state, respectively. The investigations demonstrate that the synthesized novel complexes might be practically useful in electroluminescent devices, bio-assays, and liquid lasers due to their attractive photoluminescent properties.

关键词： samarium complexes Luminescence Thermal analysis Quantum yield

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Implementation of drone technology for farm monitoring&pesticide spraying:A review

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Information Processing in Agriculture 2023年第2期10卷 192-203页

作者： Abdul Hafeez Mohammed Aslam Husain s.P.singh Anurag chauhan Mohd.Tauseef Khan Navneet Kumar Abhishek chauhan s.K.soni Rajkiya Engineering College Ambedkar NagarUP 224122India Rajkiya Engineering College BandaUP 210201India Rajkiya Engineering College BijnorUP 246725India MMMUT GorakhpurUP 273016India

The world receives more than 200 thousand people in a day and it is expected that the total world population will reach 9.6 billion by the year *** will result in extra food demand,which can only be met from enhanced crop ***,modernization of the agricultural sector becomes the need of the *** are many constraints that are responsible for the low production of crops,which can be overcome by using drone technology in the agriculture *** paper presents an analysis of drone technologies and their modifications with time in the agriculture sector in the last *** application of drones in the area of crop monitoring,and pesticide spraying for Precision Agriculture(PA)has been *** work done related to drone structure,multiple sensor development,innovation in spot area spraying has been ***,the use of Artificial Intelligent(AI)and deep learning for the remote monitoring of crops has been discussed.

关键词： Unmanned Aerial Vehicle Agriculture drone Pesticide spraying Crop monitoring Precision agriculture

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Weed Management in Rainfed Upland Rice Fields under Varied Agro-Ecologies in Nigeria

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Rice science 2022年第4期29卷 328-339页

作者： Oyebanji O.ALAGBO Oluyemisi A.AKINYEMIJU Bhagirath s.chauhan Department of Crop Production and Protection Faculty of AgricultureObafemi Awolowo UniversityIle-Ife 220005Nigeria Department of Crop Soil and Pest ManagementOndo State University of Science and TechnologyOkitipupa 353Ondo-StateNigeria Queensland Alliance for Agriculture and Food Innovation/school of Agriculture and Food sciences The University of QueenslandGatton 4343QueenslandAustralia

The demand for rice to meet the dietary need in low-income countries is expected to witness an exponential rise as the population *** the rice demand domestically has remained challenging due to significant yield loss caused by several biotic and abiotic *** these factors,one of the most important is the high weed pressure that ravages the upland rice *** Nigeria,several independent weed control techniques,such as physical,chemical and cultural methods,have been recommended and adopted for weed control across varying rice upland ***,outcomes of these approaches when used independently have not consistently led to an increase in *** remains an outstanding deficit between the actual yield and the potential rice *** review aimed to identify potential research gaps,and quest effective and sustainable weed management strategies in smallholder upland rice farming systems in Nigeria.A critical analysis of studies suggests the potential of sustainable weed management practices if adopted and adapted smartly in different upland ecologies in *** of upland rice against weeds can be enhanced through strategic integration of weed competitive cultivars,optimum nitrogen application timings(within weed-free periods),uniform plant spacing,and high seeding rates,with conventional herbicide/manual weed control ***,such management practices can only be engaged where inputs are supplied on time and the technical know-how is extended to *** review equally highlights potential research gaps for further studies.

关键词： herbicide integrated weed management weed flora tillage practice rainfed upland rice

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Functionalization of alumina particles to improve the performance of eco-friendly brake-pads

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Friction 2021年第5期9卷 1213-1226页

作者： Vanvirsinh chauhan Jayashree BIJWE Ashish DARPE Centre for Automotive Research and Tribology(formerly ITMMEC) Indian Institute of Technology DelhiHauz-KhasNew Delhi-110016India Mechanical Engineering Department Indian Institute of Technology DelhiHauz-KhasNew Delhi-110016India

Abrasives,such as oxides of alumina(Al),silica(si),zirconia(Zr),chromium(Cr)etc.,are added to raise the friction level and also to remove the glaze on the disc so that surface will be rejuvenated continuously during braking and will contribute to maintain the desired friction ***,these inorganic particles have less adhesion with the resin/binder and hence are easily dug out during wearing process contributing to higher *** efforts are made to enhance the filler‐matrix adhesion,not only the wear of friction material(FM)should reduce,the particles may stay for a longer time on the tribo‐surface of the pads to contribute fully towards controlling the coefficient of friction(μ).In the present study,alumina particles were selected for siloxane treatment to improve the filler‐matrix *** types of eco‐friendly(free from asbestos and Cu)brake‐pads were developed using alumina as a theme ingredient(treated and untreated)keeping all the parent formulation *** additional type of brake‐pads without alumina particles was also developed to observe the effect of abrasive particles on the tribo‐*** performance properties(physical,mechanical,and tribological)of brake‐pads were compared when evaluated in identical *** tribotesting was done on full‐scale brake inertia dynamometer following the procedure in Japanese automobile standard(JAsO C 406).It was observed that siloxane treatment affected both friction and wear of brake‐pads in a beneficial *** resistance got increased 35%for siloxane treated *** surfaces were analysed using scanning electron microscopy(sEM)and energy dispersive X‐ray(EDAX)technique.

关键词： friction materials brake‐pads siloxane treatment friction modifiers inertia brake‐dynamometer

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A novel reconfiguration of the solar array to enhance peak power and efficiency under partial shading conditions:experimental validation

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Clean Energy 2023年第4期7卷 824-842页

作者： Vijay Laxmi Mishra Yogesh K.chauhan K.s.Verma EED KNIT SultanpurU.P.Pin-228118India

Non-homogeneous irradiation patterns and temperature levels immensely affect the performance of solar photovoltaic *** shading conditions on solar arrays reduce the peak power and *** paper provides a new remedy called a novel Ramanujan reconfiguration(NRR)to eliminate this physical shading problem in solar photovoltaic *** is a static-based reconfigured technique that is built using a three-diode model with the help of the MATLAB®/simulink®*** special feature of the proposed NRR technique is that when shade occurs on the solar modules,it gets realigned in a particular row,column,diagonal,corner,centre and middle peripheral *** helps over a wide range of shade dispersion on the solar *** novel topology is tested against the conventional total cross-tied(TCT)model and recently introduced advanced reconfigured models,namely odd–even topology(OET)and Kendoku topology(KDT).The results are tested under certain shading *** proposed NRR technique increases the peak power by 4.45,2.15 and 2.17 W under the first shading condition regarding TCT,OET and *** efficiency is improved by 0.51–2.18%under the third shading condition compared with other considered models in this *** addition,NRR leads to smooth output curves under the second,third and fourth shading conditions,effectively mitigating the local power *** experimental results show the proposed enhanced performance of the novel model against the other *** Abstract Remedy for physical problem correlated with solar photovoltaics Comparison with traditional and recent solar models Conclusion:NRR has effectively handled the problem related with solar *** has improved the efficiency up to 31.44%under ***,smooth output curves under s2-s4 shows its effectiveness in mitigating the local power *** power gain at 3.94%under s4 is achieved by novel ***-time verification proves the supremacy of novel proposed model over o

关键词： efficiency partial shading conditions peak power Ramanujan reconfiguration solar array total cross-tied three-diode model

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Assessment of High-Frequency Performance Limits of Graphene Field-Effect Transistors

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Nano Research 2011年第6期4卷 571-579页

作者： Jyotsna chauhan Jing Guo Department of Electrical and Computer Engineering University of Florida Gainesville FL 32611-6130 USA

High frequency performance limits of graphene field-effect transistors （FETs） down to a channel length of 20 nm have been examined by using self-consistent quantum simulations. The results indicate that although Klein band-to-band tunneling is significant for sub-100 nm graphene FETs, it is possible to achieve a good transconductance and ballistic on-off ratio larger than 3 even at a channel length of 20 nm. At a channel length of 20 nm, the intrinsic cut-off frequency remains at a few THz for various gate insulator thickness values, but a thin gate insulator is necessary for a good transconductance and smaller degradation of cut-off frequency in the presence of parasitic capacitance. The intrinsic cut-off frequency is close to the LC characteristic frequency set by graphene kinetic inductance （L） and quantum capacitance （C）, which is about 100 GHz-um divided by the gate length.

关键词： Field effect transistor (FET) radio frequency (RF) carbon nanotube (CNT) intrinsic cut-off frequency transconductance

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