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Endovascular Management of Vertebral Artery Aneurysms

International Journal of Clinical Medicine 2022年第12期13卷 584-589页

作者： puay yong ng Mt Elizabeth Medical Centre Singapore

Background: The management outcome of a series of ruptured vertebral artery (VA) aneurysms was reviewed. Method: This is a retrospective study of prospectively collected data of 60 cases with ruptured VA aneurysms in the author’s database from the year 2004. All cases were managed with coiling, stent-assisted coiling, flow diversion or endovascular parent artery sacrifice. Nimodipine and hypertensive, hypervolemic therapy was applied as standard. Outcome was assessed at 6 months with modified Rankin score (mRS). Results: There were 26 females and 34 males. Age range is 18 to 70 with a mean age of 42. There were 27 dissecting aneurysms and 33 saccular aneurysms. 50 (83%) cases were World Federation of Neurological Surgeons (WFNS) grade one to three. There were four WFNS grade four and six WFNS grade five. 25 cases of dissecting aneurysms were managed with parent artery coil occlusion. Two dissecting aneurysms affecting the dominant VA were treated with flow diverters. At 6 months follow up 50 (83%) achieved good outcome with mRS one to two. There were eight cases with poor outcome and two deaths. Six-month follow-up MR angiogram documented stable occlusion for the 24 cases with dissecting aneurysms treated with parent artery coil occlusion who survived. The two treated with flow diversion demonstrated good remodelling at 6 months on angiography. Six-month follow-up angiogram for the 32 cases of saccular aneurysm who survived documented stable aneurysm obliteration. Conclusion: Good outcome can be achieved with endovascular treatment for ruptured VA aneurysms. Parent artery occlusion is a safe and effective technique for ruptured VA dissecting aneurysm.

关键词： Vertebral Artery Aneurysm Dissecting Aneurysm Dissection

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Update on Carotid Stenting and Endarterectomy

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International Journal of Clinical Medicine 2021年第10期12卷 433-440页

作者： puay yong ng Mt Elizabeth Medical Centre Singapore

The role of carotid stenting and endarterectomy has been evolving over the past few decades. Results of recent randomized trials have added more insights to the indications of the two established interventions for symptomatic moderate to severe stenosis as well as asymptomatic carotid stenosis. Despite a wide range of complication rates in various trials for both symptomatic and asymptomatic carotid stenosis, benefits of the two interventions have been consistently demonstrated for symptomatic moderate stenosis as well as asymptomatic severe stenosis albeit with lower benefit margin for asymptomatic disease. Intervention for asymptomatic carotid stenosis should only be considered when the complication rate can be maintained below 3%.

关键词： Carotid Stenosis Stenting

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A rare case of isolated castrate resistant bilateral testicular metastases in advanced prostate cancer

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Asian Journal of Urology 2018年第2期5卷 127-130页

作者： Jiarui Su Edwin Jonathan Aslim Hakan Aydin puay Hoon Tan Henry Sun Sien Ho Department of Urology Singapore General HospitalSingapore Department of Anatomical Pathology Singapore General HospitalSingapore Division of Pathology Singapore General HospitalSingapore

Testicular metastasis is rare with the prostate being the most common site of primary *** report a case of a 72-year-old man with castration-resistant prostate cancer(CRPC)and known metastases to bone and lymph nodes,who developed bilateral painful swollen testes 3 years after the initial diagnosis of prostate *** had first presented with lower urinary tract symptoms(LUTS)with suspicious findings on digital rectal examination of the prostate,and an elevated serum prostate specific antigen(PSA)level of 129 ng/*** prostate biopsy revealed Gleason 4þ5 *** staging showed locally advanced prostate cancer with extensive metastases to bone and pelvic and retroperitoneal lymph *** was given hormonal therapy for over 2 years until progression to *** months later he developed painful bilateral testicular swellings,and serum markers for testicular germ cell cancer were *** orchiectomy was performed,showing metastatic prostate cancer(Gleason 4þ5)on *** month postoperatively his PSA level dropped to 0.1 ng/mL from a presurgery level of 6.24 ng/mL.

关键词： Castration-resistant prostate cancer Metastases Testicular tumor Orchiectomy

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保存回忆，保存古建筑的概念化工具——访香港中文大学建筑系教授何培斌

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建筑技术及设计 2005年第10期 26-27页

作者： Sherry Yang(翻译) Wendy ng(校译)

保存过去是可持续发展的一部分，保存古建筑，促发人们思考未来的问题。在今年七月，由香港珠海学院（Chu Hai College of Higher Education）建筑系主办的一场题为“文化传承：可持续发展及美学”的研讨会，来自香港、新加坡、台湾和... 详细信息

保存过去是可持续发展的一部分，保存古建筑，促发人们思考未来的问题。在今年七月，由香港珠海学院（Chu Hai College of Higher Education）建筑系主办的一场题为“文化传承：可持续发展及美学”的研讨会，来自香港、新加坡、台湾和内地的政府官员、专家学者及民间古迹保护人士就一系话题进行探讨：新加坡政府如保透过规划（MASTER PLAN 2003）保存其城市的独特身份？香港市民近期侃谈集体回忆的可贵，究竟与城市发展和古迹保护有何关系？极速发展中的北京，传统胡同和四合院尚余多少？香港市区重建背后的理念是什么？台湾的传统民居今天面貌如何等。

关键词：大学建筑古建筑保存香港概念化可持续发展教授中文工具

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