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中华优秀传统文化融入统一战线工作价值研究

未来与发展 2024年第8期48卷 33-36页

作者：孙璞孙立华锦州医科大学药学院辽宁锦州121001 渤海大学历史文化学院辽宁锦州121013

中华优秀传统文化博大精深,新时代要以中华优秀传统文化为纽带,凝心聚力,发展和壮大统一战线。团结党外人士,增强政治认同、思想认同、理论认同、情感认同。以中华传统文化精华推进新时代统战工作,坚持人民至上,传承民为邦本的文化基因... 详细信息

中华优秀传统文化博大精深,新时代要以中华优秀传统文化为纽带,凝心聚力,发展和壮大统一战线。团结党外人士,增强政治认同、思想认同、理论认同、情感认同。以中华传统文化精华推进新时代统战工作,坚持人民至上,传承民为邦本的文化基因;坚持自信自立,传承自强不息的文化基因;坚持守正创新,传承恪守正道、革故鼎新的文化基因;坚持问题导向,传承实事求是、知行合一的文化基因;坚持系统观念,传承天人合一的文化基因;坚持胸怀天下,传承天下为公的文化基因。

关键词：中华优秀传统文化统战工作价值研究

circ_BACH2通过调控miR-370-3p影响甲状腺乳头状癌的恶性生物学行为

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中华肿瘤杂志 2024年第7期46卷 663-675页

作者：孙璞冯勇周连仲裴斐苏玢乔晓丞天津市第四中心医院耳鼻咽喉头颈外科天津300140 上海理工大学附属市东医院耳鼻咽喉科上海200438

目的探讨circ_BACH2对甲状腺乳头状癌恶性生物学行为的影响及分子机制。方法收集天津市第四中心医院2017—2019年51例甲状腺乳头状癌患者的癌组织和癌旁正常组织。实时荧光定量PCR法检测癌组织、癌旁正常组织和细胞中circ_BACH2、miR-37... 详细信息

目的探讨circ_BACH2对甲状腺乳头状癌恶性生物学行为的影响及分子机制。方法收集天津市第四中心医院2017—2019年51例甲状腺乳头状癌患者的癌组织和癌旁正常组织。实时荧光定量PCR法检测癌组织、癌旁正常组织和细胞中circ_BACH2、miR-370-3p和GIT1 mRNA的表达水平,流式细胞术检测细胞凋亡情况和细胞周期变化,平板克隆形成实验检测细胞克隆形成数,细胞计数试剂盒8检测细胞增殖能力,Transwell检测细胞迁移和侵袭能力,Western blot法检测蛋白表达,双荧光素酶报告实验检测circ_BACH2、miR-370-3p和GIT1之间的靶向关系,裸鼠成瘤实验检测抑制circ_BACH2的表达对小鼠体内肿瘤的影响。结果甲状腺乳头状癌组织中circ_BACH2、GIT1 mRNA和蛋白表达水平高于癌旁正常组织,miR-370-3p表达水平低于癌旁正常组织,甲状腺癌细胞TPC-1、SW579中circ_BACH2、GIT1 mRNA和蛋白表达水高于人甲状腺正常细胞Nthy-ori3-1,miR-370-3p表达水平低于Nthy-ori3-1细胞(均P<0.05)。GIT1 mRNA表达水平与miR-370-3p表达水平呈负相关(r=-0.634),circ_BACH2表达水平与GIT1 mRNA表达水平呈正相关(r=0.635),circ_BACH2表达水平与miR-370-3p表达水平呈负相关(r=-0.394,均P<0.05)。circ_BACH2与miR-370-3p具有结合位点,GIT1的3'UTR与miR-370-3p具有结合位点。si-circ_BACH2组TPC-1、SW579细胞G0/G1期细胞比例高于si-NC组,S期细胞比例、细胞吸光度值低于si-NC组,细胞克隆形成数[分别为(43±5)个和(54±8)个]低于si-NC组[分别为(100±6)个和(100±9)个],细胞凋亡率[分别为(19.60±2.40)%和(18.10±2.10)%]高于si-NC组[分别为(4.30±0.20)%和(5.10±0.23)%],细胞迁移数[分别为(61±7)个和(58±6)个]、细胞侵袭数[分别为(45±6)个和(47±4)个]均低于si-NC组[分别为(134±15)个、(112±11)个、(113±11)个和(92±9)个,均P<0.001]。si-circ_BACH2组细胞中Snail、Twist1表达水平低于si-NC组,E-cadherin表达水平高于si-NC组(均P<0.001)。抑制miR-370-3p的表达逆转敲减circ_BACH2对甲状腺乳头状癌细胞增殖、迁移、侵袭和凋亡的影响,过表达GIT1逆转过表达miR-370-3p对甲状腺癌细胞增殖、迁移、侵袭和凋亡的影响。注射稳定转染sh-circ_BACH2的TPC-1细胞的裸鼠在培养35 d后肿瘤体积缩小[(535±91)mm^(3)和(857±114)mm^(3)],肿瘤重量减少[(0.62±0.13)mg和(1.06±0.15)mg,均P<0.05]。裸鼠肿瘤组织中circ_BACH2、GIT1 mRNA表达水平降低,miR-370-3p mRNA表达水平升高(均P<0.05)。结论抑制circ_BACH2可能通过靶向调控miR-370-3p/GIT1从而抑制体外甲状腺乳头状癌细胞的增殖、迁移、侵袭,促进细胞凋亡,并抑制体内肿瘤的生长。

关键词：甲状腺肿瘤 circ_BACH2 miR-370-3p GIT1

教育优先发展视域下学校体育高质量育人的理论意涵与实践路径

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首都体育学院学报 2024年第1期36卷 78-87页

作者：燕凌孙璞王莉芳刘海元首都体育学院心理学与教育学教研室北京100191 首都体育学院研究生部北京100191

教育优先发展是党和国家提出并长期坚持的重大方针,高质量发展是教育优先发展在新阶段的重要表征。学校体育高质量育人作为教育高质量发展的重要构成,体现出育人目标的素养导向、育人过程的生本导向和要素导向以及育人功效的多元导向等... 详细信息

教育优先发展是党和国家提出并长期坚持的重大方针,高质量发展是教育优先发展在新阶段的重要表征。学校体育高质量育人作为教育高质量发展的重要构成,体现出育人目标的素养导向、育人过程的生本导向和要素导向以及育人功效的多元导向等特征。新时期推进学校体育高质量育人需要坚持把立德树人作为根本任务,着力培养青少年的核心素养;提升学生体育学习的实际获得感,提高体育师资培养质量,推进体育家校合作;科学认识学校体育促进青少年全面发展的育人价值,充分发挥学校体育的育体功能和育心功能。

关键词：教育优先发展学校体育高质量育人

A NEW HIGH PERFORMANCE SPARSE STATIC SOLVER IN FINITE ELEMENT ANALYSIS WITH LOOP-UNROLLING

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Acta Mechanica Solida Sinica 2005年第3期18卷 248-255页

作者： Chen pu sun Shuli LTSC Department of Mechanics and Engineering Science Peking University Beijing 100871 China

In the previous papers, a high performance sparse static solver with two-level unrolling based on a cell-sparse storage scheme was reported. Although the solver reaches quite a high efficiency for a big percentage of finite element analysis benchmark tests, the MFLOPS （million floating operations per second） of LDL^T factorization of benchmark tests vary on a Dell Pentium IV 850 MHz machine from 100 to 456 depending on the average size of the super-equations, i.e., on the average depth of unrolling. In this paper, a new sparse static solver with two-level unrolling that employs the concept of master-equations and searches for an appropriate depths of unrolling is proposed. The new solver provides higher MFLOPS for LDL^T factorization of benchmark tests, and therefore speeds up the solution process.

关键词： high performance computing sparse matrix finite element analysis

公平竞争审查制度例外规定适用的优化——以地方政府补贴为视角

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长春理工大学学报（社会科学版） 2024年第3期37卷 52-58页

作者：杨健梅王寒孙璞长春理工大学法学院吉林长春130022 吉林省市场监督管理厅反垄断处吉林长春130000

公平竞争审查制度是当前我国市场经济发展中的一项重要制度,其中例外规定作为该制度的重要组成部分,起着重要的调节与补充作用。地方政府补贴对地区的市场公平竞争有着重要的影响,将地方政府补贴纳入公平竞争审查的工作内容之中也是公... 详细信息

公平竞争审查制度是当前我国市场经济发展中的一项重要制度,其中例外规定作为该制度的重要组成部分,起着重要的调节与补充作用。地方政府补贴对地区的市场公平竞争有着重要的影响,将地方政府补贴纳入公平竞争审查的工作内容之中也是公平竞争审查制度的应有之举。以公平竞争审查制度中的例外规定作为切入点,从地方政府补贴的公平竞争审查的角度出发,结合国内外的公平竞争审查制度中的例外规定,提出当前我国公平竞争审查制度中地方政府补贴的例外规定的适用存在的问题,并提出优化建议。

关键词：公平竞争审查地方政府补贴例外制度

Universal Pseudo-PT-Antisymmetry on One-Dimensional Atomic Optical Lattices

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Communications in Theoretical Physics 2018年第9期69卷 303-310页

作者： Xin Wang Chang-pu sun Beijing Computational Science Research Center Beijing 100193China Graduate School China Academy of Engineering PhysicsBeijing 100193China

We present the interesting result that under sinusoidal field detuning setting along the propagation direction of 1D atomic lattices, the probe susceptibility response of the lattices, regardless of atomic configuration, uniformly demonstrates pseudo-PT-antisymmetry, which by our definition corresponds to n(z)=-n*(-z), the complex refractive index antisymmetry along propagation axis, and when being cast back to quantum mechanical side, corresponds to V (x, t)=-V*(x,-t), the conjugate time-reversal antisymmetry of complex potential. We define this as the pseudoPT-antisymmetry, and prove the reason for this phenomenon to be the quantum-mechanical nature described by master equation under weak field approximation for any configuration of 1D atomic lattices. This work will help to deepen the understanding of origin of optical response features of atomic lattices, and will certainly open up the gate to a more rigorous, durable and flexible method of atomic optical lattice design.

关键词： pseudo-PT-antisymmetry conjugate time-reversal antisymmetry zigzag-type atom configuration

Meta analysis on the relationship between gene polymorphisms of vascular endothelial growth factorand retinal prognosis risk of prematurity

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International Journal of Ophthalmology(English edition) 2012年第3期5卷 397-400页

作者： Jun Zhai, Ying-pu sun Reproductive Center the First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 Henan Province China Department of Gynaecology and Obstetrics People's Hospital of Zhengzhou Zhengzhou 450003 Henan Province China

AIM: To explore the relationship between gene polymorphisms of (VEGF) and retinopathy of prematurity (ROP). METHODS: Literature materials related to gene polymorphisms of VEGF and ROP in pubMed, EMBASE, Cochrane and CBM database were retrieved. These materials were screened according to inclusion and exclusion standards. Patients diagnosed with ROP in clinic were regarded as control group and ROP patients who were in treatment were regarded as observation group. The indexes in two groups were matched except birth weight (BW), gender and gestational weeks. Meta5.1 was used to analyze the relationship between gene polymorphisms of VEGF and ROP. RESULTS: Four random control tests (RCT) were included in this research, including 2611 patients. Met) analysis results showed that VEGF affected ROP, having statistical significance. The combined ratio was 0.44 (95% CI, 0.07, 0.80), 0.42 (95%CI, 0.09, 0.74) and 0.75 (95%CI, 0.02, 1.49), respectively. Carrying +405 allele might increase the premature infants risk of having ROP. CONCLUSION: ROP may be related to its carrying of +405 allele. Large-scale, multi-factor RCT researches are still needed in order to identify the relation between VEGF and ROP.

关键词： polymorphisms of vascular endothelial growth factor premature infant retinopathy Meta analysis

Directional quantum random walk induced by coherence

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Frontiers of physics 2020年第2期15卷 13-25页

作者： Jin-Fu Chen Yu-Han Ma Chang-pu sun Beijing Computational Science Research Center Beijing 100193China Graduate School of China Academy of Engineering Physics No.10 Xibeiwang East RoadHaidian DistrictBeijing 100193China

Quantum walk (QW), which is considered as the quantum counterpart of the classical random walk (CRW), is actually the quantum extension of CRW from the single-coin interpretation. The sequential unitary evolution engenders correlation between different steps in QW and leads to a non-binomial position distribution. In this paper, we propose an alternative quantum extension of CRW from the ensemble interpretation, named quantum random walk (QRW), where the walker has many unrelated coins, modeled as two-level systems, initially prepared in the same state. We calculate the walker's position distribution in QRW for different initial coin states with the coin operator chosen as Hadamard matrix. In one-dimensional case, the walker's position is the asymmetric binomial distribution. We further demonstrate that in QRW, coherence leads the walker to perform directional movement. For an initially decoherenced coin state, the walker's position distribution is exactly the same as that of CRW. Moreover, we study QRW in 2D lattice, where the coherence plays a more diversified role in the walker's position distribution.

关键词： quantum walk random walk ensemble interpretation directional walking coherence

VenomAttack: automated and adaptive activity hijacking in Android

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Frontiers of Computer Science 2023年第1期17卷 187-204页

作者： pu sun Sen CHEN Lingling FAN Pengfei GAO Fu SONG Min YANG School of Information Science and Technology ShanghaiTech UniversityShanghai 201210China Shanghai Institute of Microsystem and Information Technology Chinese Academy of SciencesShanghai 200050China University of Chinese Academy of Sciences Beijing 100049China College of Intelligence and Computing Tianjin UniversityTianjin 300350China College of Cyber Science Nankai UniversityTianjin 300350China School of Computer Science Fudan UniversityShanghai 200438China

Activity hijacking is one of the most powerful attacks in Android. Though promising, all the prior activity hijacking attacks suffer from some limitations and have limited attack capabilities. They no longer pose security threats in recent Android due to the presence of effective defense mechanisms. In this work, we propose the first automated and adaptive activity hijacking attack, named VenomAttack, enabling a spectrum of customized attacks (e.g., phishing, spoofing, and DoS) on a large scale in recent Android, even the state-of-the-art defense mechanisms are deployed. Specifically, we propose to use hotpatch techniques to identify vulnerable devices and update attack payload without re-installation and re-distribution, hence bypassing offline detection. We present a newly-discovered flaw in Android and a bug in derivatives of Android, each of which allows us to check if a target app is running in the background or not, by which we can determine the right attack timing via a designed transparent activity. We also propose an automated fake activity generation approach, allowing large-scale attacks. Requiring only the common permission INTERNET, we can hijack activities at the right timing without destroying the GUI integrity of the foreground app. We conduct proof-of-concept attacks, showing that VenomAttack poses severe security risks on recent Android versions. The user study demonstrates the effectiveness of VenomAttack in real-world scenarios, achieving a high success rate (95%) without users’ awareness. That would call more attention to the stakeholders like Google.

关键词： Android activity hijacking Android security mobile security