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一种用于大视场成像和偏振光谱探测的微型可重构超构光学系统

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Engineering 2024年第4期35卷 67-73页

作者： Fei Zhang Minghao Liao Mingbo pu Yinghui guo Lianwei Chen Xiong Li Qiong He Tongtong Kang Xiaoliang Ma Yuan Ke Xiangang Luo State Key Laboratory of Optical Technologies on Nano-Fabrication and Micro-Engineering Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209China National Key Laboratory of Optical Field Manipulation Science and Technology Chinese Academy of SciencesChengdu 610209China School of Optoelectronics University of Chinese Academy of SciencesBeijing 100049China Research Center on Vector Optical Fields Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209China Tianfu Xinglong Lake Laboratory Chengdu 610299China

Wide-angle imaging and spectral detection play vital roles in tasks such as target tracking,object classification,and anti-camouflage.However,limited by their intrinsically different architectures,as determined by frequency dispersion requirements,their simultaneous implementation in a shared-aperture system is difficult.Here,we propose a novel concept to realize reconfigurable dual-mode detection based on electrical-control tunable metasurfaces.As a proof-of-concept demonstration,the simultaneous implementation of wide-angle imaging and polarization-spectral detection in a miniature sharedaperture meta-optical system is realized for the first time via the electrical control of cascaded catenary-like metasurfaces.The proposed system supports the imaging(spectral)resolution of approximately 27.8 line-pairs per millimeter(lp·mm^(-1);~80 nm)for an imaging(spectral)mode from 8 to 14 lm.This system also bears a large field of view of about 70,enabling multi-target recognition in both modes.This work may promote the miniaturization of multifunctional optical systems,including spectrometers and polarization imagers,and illustrates the potential industrial applications of meta-optics in biomedicine,security,space exploration,and more.

关键词： Metasurfaces Reconfigurable Imaging Spectral

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小型水库存在的安全隐患处理措施

农业灾害研究 2023年第11期13卷 314-316页

作者：濮国鹏高台县红崖子水利管理所甘肃高台734300

随着我国农村经济的快速发展,农村对水资源的需求也不断提高,小型水库在农村地区的建设和运维成了一项重要任务。然而,在小型水库的建设和管理过程中,面临一定的安全隐患,可能对周边居民的生命财产安全和农村经济的可持续发展造成严重... 详细信息

随着我国农村经济的快速发展,农村对水资源的需求也不断提高,小型水库在农村地区的建设和运维成了一项重要任务。然而,在小型水库的建设和管理过程中,面临一定的安全隐患,可能对周边居民的生命财产安全和农村经济的可持续发展造成严重影响。因此,对小型水库存在的安全隐患进行科学、系统的处理,具有重要的现实意义。分析了小型水库存在的安全隐患、排查意义,总结了小型水库存在的安全隐患问题,提出了针对性的处理措施,以供参考。

关键词：小型水库安全隐患处理措施

Investigation on Breakdown Characteristics of Various Surface Terminal Structures for GaN-Based Vertical P-i-N Diodes

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Journal of Applied Mathematics and Physics 2024年第2期12卷 554-568页

作者： Song Shi Guanyu Wang Yingcong Xiang Chuan guo Xing Wang Yinlin pu Huilan Li Zhixian Li School of Optoelectronic Engineering Chongqing University of Posts and Telecommunications Chongqing China

GaN-based vertical P-i-N diode with mesa edge terminal structure due to electric field crowding effect, the breakdown voltage of the device is significantly reduced. This work investigates three terminal structures, including deeply etched, bevel, and stepped-mesas terminal structures, to suppress electric field crowding effects at the device and junction edges. Deeply-etched mesa terminal yields a breakdown voltage of 1205 V, i.e., 89% of the ideal voltage. The bevel-mesa terminal achieves about 89% of the ideal breakdown voltage, while the step-mesa terminal is less effective in mitigating electric field crowding, at about 32% of the ideal voltage. This work can provide an important reference for the design of high-power, high-voltage GaN-based P-i-N power devices, finding a terminal protection structure suitable for GaNPiN diodes to further enhance the breakdown performance of the device and to unleash the full potential of GaN semiconductor materials.

关键词： GaN P-i-N Mesa Edge Terminal Electric Field Crowding

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei pu Xin-Yian guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late stroke.Indeed,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain tissue.Our previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently unclear.To simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic stroke.We found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous acid.Further,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid hydrazide.Our results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/reoxygenation.However,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and astrocytes.This suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion injury.Lower levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-catenin.By transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear translocation.Altogether,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

亚胺培南联合磷霉素对多重耐药鲍曼不动杆菌的试验研究

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中国感染控制杂志 2023年第1期22卷 74-79页

作者：王亚萍郭普汪华学蚌埠医学院第一附属医院重症医学科安徽蚌埠233004 蚌埠医学院第一附属医院检验科安徽蚌埠233004

目的探索以亚胺培南为基础用药,对临床分离多重耐药鲍曼不动杆菌(MDR-AB)的体内外抗菌方法。方法用微量肉汤稀释法及棋盘法测定7株临床分离的MDR-AB对亚胺培南、磷霉素、阿米卡星、替加环素、多粘菌素B 5种抗菌药物的最低抑菌浓度(MIC)... 详细信息

目的探索以亚胺培南为基础用药,对临床分离多重耐药鲍曼不动杆菌(MDR-AB)的体内外抗菌方法。方法用微量肉汤稀释法及棋盘法测定7株临床分离的MDR-AB对亚胺培南、磷霉素、阿米卡星、替加环素、多粘菌素B 5种抗菌药物的最低抑菌浓度(MIC)及联合MIC,并计算部分抑菌浓度指数(FICI)。用时间杀菌曲线法判断亚胺培南联合磷霉素的杀菌效果。选取菌株AB6624、AB0153构建体外生物膜模型,结晶紫染色法半定量生物膜。激光共聚焦显微镜观察使用亚胺培南联合磷霉素对生物膜细菌的杀伤作用。流式细胞仪检测亚胺培南及磷霉素单药与联合用药对细菌活性氧(ROS)表达的影响。建立大蜡螟感染模型,记录亚胺培南及磷霉素单药与联合用药时大蜡螟存活率。结果亚胺培南联合磷霉素对5株MDR-AB具有协同作用;亚胺培南联合磷霉素对菌株AB6624、AB0153分别在4、8 h的菌落数较单药组降低>2log 10 CFU/mL;亚胺培南联合磷霉素抑制菌株生物膜形成并对菌株AB0153生物膜结构具有破坏作用;亚胺培南联合磷霉素可以提高菌株AB0153胞内ROS水平,差异具有统计学意义(P<0.05);与对照组相比,亚胺培南联合磷霉素处理组大蜡螟生存率提高(中位生存时间96 h),差异具有统计学意义(P=0.022)。结论亚胺培南联合磷霉素对MDR-AB具有协同作用,并可能通过抑制生物膜形成及提高细菌胞内ROS水平发挥作用。

关键词：多重耐药鲍曼不动杆菌亚胺培南磷霉素生物膜大蜡螟联合药敏试验

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世界社会主义视阈下的中国特色社会主义

教学与研究 2008年第8期 52-57页

作者：蒲国良中国人民大学国际关系学院北京100872

波澜壮阔的世界社会主义运动,是人类向着民主、自由、公正、和谐的理想社会目标前进的积极探索。其间既取得过辉煌的成就,也遭遇过严重的挫折和失败。把中国特色社会主义放在世界社会主义范围内去考察,我们可以看到,中国特色社会主义是... 详细信息

波澜壮阔的世界社会主义运动,是人类向着民主、自由、公正、和谐的理想社会目标前进的积极探索。其间既取得过辉煌的成就,也遭遇过严重的挫折和失败。把中国特色社会主义放在世界社会主义范围内去考察,我们可以看到,中国特色社会主义是世界社会主义运动的新发展,是社会主义建设的新模式,是社会主义实践的新探索,是社会主义理论的新阐发,凸显了当代社会主义的新形态。

关键词：中国特色社会主义世界社会主义科学社会主义

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新时代中国特色社会主义的世界意义

理论与改革 2018年第2期 11-18页

作者：蒲国良中国人民大学国际关系学院

经过长期努力,中国特色社会主义进入了新时代,这是我国发展新的历史方位。理解新时代中国特色社会主义的世界意义,我们可以尝试从国际共产主义运动、世界社会主义运动、世界现代化进程与人类文明发展历程四个宏观维度去把握,并由此可以... 详细信息

经过长期努力,中国特色社会主义进入了新时代,这是我国发展新的历史方位。理解新时代中国特色社会主义的世界意义,我们可以尝试从国际共产主义运动、世界社会主义运动、世界现代化进程与人类文明发展历程四个宏观维度去把握,并由此可以得出结论:新时代中国特色社会主义已经成为国际共产主义运动的新亮点,正在形成世界社会主义的新模式,日渐呈现世界现代化道路的新探索,必将成为人类文明进步的新支点。

关键词：新时代中国特色社会主义习近平新时代中国特色社会主义思想当代世界社会主义国际共产主义运动史

Single-cell characterization of major components of plant cell walls in situ by Raman spectroscopy

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Science China Life Sciences 2024年第8期 1772-1774页

作者： Yujian Li Weiwei Shen Xi Zhang Yaning Cui Yuanyuan Zhao Yayu guo Xiaojuan Li Shuizhong Wang guoyong Song pu Wang Jianfeng Ma Jinxing Lin State Key Laboratory of Efficient Production of Forest Resources College of Biological Sciences and TechnologyBeijing Forestry University Institute of Tree Development and Genome Editing Beijing Forestry University National Engineering Research Center of Tree Breeding and Ecological Restoration College of Biological Sciences and TechnologyBeijing Forestry University Beijing Key Laboratory of Lignocellulosic Chemistry Engineering Research Center of Forestry Biomass Materials and EnergyMinistry of EducationBeijing Forestry University Beijing Advanced Innovation Center for Biomedical Engineering School of Biological Science and Medical EngineeringBeihang University Key lab of Bamboo and Rattan Science & Technology International Center for Bamboo and Rattan

Dear Editor,Plant cell walls are complex and dynamic structures that are mainly composed of polysaccharide polymers such as cellulose,hemicellulose,and pectin,in addition to substantial amounts of the non-saccharide p...

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国外一些政党开展党内政治生活的得失探析

理论与改革 2020年第1期 129-138页

作者：蒲国良中国人民大学国际关系学院

正常而有效地开展党内政治生活是一个政党保持凝聚力、向心力和感召力的现实要求。但当今国外许多政党受内外环境的深刻影响,党内政治生活难以开展或者走偏跑调甚至转向,给该党带来严重冲击。近期国外一些政党注重从思想、制度机制和方... 详细信息

正常而有效地开展党内政治生活是一个政党保持凝聚力、向心力和感召力的现实要求。但当今国外许多政党受内外环境的深刻影响,党内政治生活难以开展或者走偏跑调甚至转向,给该党带来严重冲击。近期国外一些政党注重从思想、制度机制和方式方法上重构和规范党内生活,收笼党心,提高党的行动能力。国外政党的相关经验教训,对于我党在新时代新形势下推进全面从严治党具有某些借鉴与启迪意义,值得跟踪和研究。

关键词：党内政治生活党的建设执政党建设