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Cross-Sectional study of internalised stigma and medication adherence in patients with obsessive compulsive disorder

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General Psychiatry 2020年第2期33卷 94-100页

作者： Eram Ansari Sudha Mishra Adarsh Tripathi Sujita kumar Kar pronob kumar dalai College of Nursing King George's Medical UniversityLucknowIndia Departm ent of Psychiatry King George's Medical UniversityLucknowIndia

Background Patients suffering from psychiatric disorders tend to stigmatise themselves which had been linked to poor adherence to *** The aim of the present study was to study internalised stigma and medication adherence and to assess the relationship between them in patients with obsessive compulsive disorder(0CD).Methods A cross-sectional study was conducted on 112 patients diagnosed with 0CD who were attending the Out-patient's department at Department of Psychiatry of a tertiary care hospital in North *** stigma and current medication adherence were assessed with Internalized Stigma of Mental Illness Scale(ISMI)and Medication Adherence Rating Scale,***-Brown Obsessive Compulsive Scale was used to assess the current severity of OCD *** and clinical details were also obtained from the patients by using a semistructured sociodemographic *** Most of the patients reported moderate level of internalised stigma with a mean ISMI score of 77.98(10.82).Most of the patients were compliant while 41.96%reported poor medication *** stigma was negatively correlated with the current medication *** severity of OCD symptoms also showed a significant positive correlation with internalised stigma and a significant negative correlation with medication *** High levels of internalised stigma were associated with lower adherence to treatment which suggests that internalised stigma may be a very important factor influencing medication adherence in patients with OCD.

关键词： patients medication Internal

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Study of Cardiac Manifestations in Patients with HIV Infection and Their Correlation with CD4 Count in Indian Population

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International Journal of Clinical Medicine 2012年第3期3卷 178-183页

作者： Ayaskanta Singh Sidhartha Das Rabindra kumar dalai Postgraduate Department of Medicine and Nodal Officer Anti Retroviral Therapy (ART) Centre SCB Medical College and Hospital Cuttack India Postgraduate Department of Medicine SCB Medical College and Hospital Cuttack India

Introduction: With advances in the management of patients living with HIV and AIDS (PLHA), not only survival has increased but manifestations of late stage HIV infection are encountered more often including cardiovascular complications. Aims and Objectives: To determine the prevalence and characteristics of cardiac manifestations in patients with HIV infection and to evaluate their correlation with CD4 count. Materials and Method: 70 consecutive patients with HIV infection admitted to Post Graduate Department of Medicine from the period of July 2010 to August 2011 were studied. All cases of PLHA diagnosed after positive ELISA test for HIV infection were included, whereas those with congenital heart disease, rheumatic heart disease, hypertension, Ischemic heart disease were excluded from the study. CD4 count and 2D echocardiography along with routine investigations were done for all patients. Result: Male to female ratio was 2:1. Echocardiographic abnormalities were seen in 58% of patients. Reduced ejection fraction (below 50%) and fractional shortening below 30% were the most common cardiac abnormality (48.7%) followed by pericardial effusion (17.4%), pulmonary artery hypertension (11.4%), dilated cardiomyopathy (8.5%), diastolic dysfunction (8.5%) and regional wall motion abnormality (1.4%) respectively. Significant statistical positive correlation was observed between low CD4 count and echocardiographic abnormalities (p < 0.0001). Pericardial effusion was seen more in patients with CD4 count below 200 (p < 0.001). Maximum number of echocardiographic abnormalities was seen in WHO clinical stage IV. Conclusions: Cardiac manifestations are frequent PLHA in our population but do not have detectable clinical manifestation. Echocardiographic abnormalities have a strong correlation with low CD4 count and occur more in advanced stage of the disease.

关键词： HIV AIDS PLHA CD4 Count Echocardiographic Findings

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