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In vitro antioxidant assessment and a rapid HPTLC bioautographic method for the detection of anticholinesterase inhibitory activity of Geophila repens

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Journal of Integrative Medicine 2017年第3期15卷 231-241页

作者： Umesh chandra Dash Atish Kumar Sahoo Regional Plant Resource Centre Medicinal & Aromatic Plant Division Forest & Environment DepartmentGovt. of Odisha Nayapalli Bhubaneswar 751015 India

OBJECTIVE： Geophila repens （L.） I. M. Johnst. （Rubiaceae）, a small, creeping, perennial herb, is claimed to have memory-enhancing property. The goal of this study was to assess its antioxidant and anticholinesterase activity and conduct a rapid bioautographic enzyme assay for screening acetylcholinesterase （ACHE） and butyrylcholinesterase （BChE） inhibition of G. repens extracts. METHODS： Antioxidant activity of G. repens extracts was assessed by performing 1,1-diphenyl-2- picrylhydrazyl （DPPH）, nitric oxide （NO）, superoxide （SOD）, hydroxyl （OH） and total antioxidant capacity （TAC） assays. Anticholinesterase activity was investigated by quantifying the AChE and BChE inhibitory activities of chloroform （CGR）, ethyl acetate （EGR） and methanol （MGR） extract fractions from G. repens leaves. A rapid high-performance thin-layer chromatography （HPTLC） bioautographic method for the detection of AChE and BChE inhibition was performed. RESULTS： Among all extract fractions, EGR exhibited the highest half maximal inhibitory concentration （IC50） in DPPH, SOD, NO, OH and TAC assays, with IC50 of （38.33 ± 3.21）, （45.14 ±1.78）, （59.81± 1.32）, （39.45 ± 0.79） and （43.76 ± 0.81 ） μg/mL respectively. EGR displayed competitive, reversible inhibition of AChE and BChE activities with IC50 of （68.63±0.45） and （59.45 ±0.45）μg/mL, respectively. Total phenolic and flavonoids contents of EGR were found to be 360.42 mg gallic acid equivalents and 257.31 mg quercetin equivalents per gram of extract. Phytoconstituents of the EGR extract that were inhibitors of cholinesterase produced white spots on the yellow background of HPTLC plates in the bioautographic test. CONCLUSION： The results of this study revealed that phenols and flavonoids could be responsible for the antioxidant, anticholinesterase activities of G. repens.

关键词： Geophila repens Alzheimer disease acetylcholinesterase butyrylcholinesterase fingerprint bioautographic phenolic, antioxidant

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Mitigating People-Park Conflicts on Resource Use through Ecotourism:A Case of the Nanda Devi Biosphere Reserve,Indian Himalaya

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Journal of Mountain Science 2011年第1期8卷 87-95页

作者： chandra Prakash KALA Rakesh Kumar MAIKHURI Ecosystem and Environment Management Indian Institute of Forest Management G.B.Pant Institute of Himalayan Environment and Development Post.

Eeotourism aims to deliver the philosophy of sustainable development through environmental conservation as well as socio-economic development. Areas with rich biodiversity and scenic beauty, like the Indian Himalayan region, have been one of the major destination centers for nature lovers from historical time. In view of conserving the rich biodiversity and natural heritage of the Himalayan region 92 protected areas have been set aside, of these Nanda Devi Biosphere Reserve （NDBR） is a well known world heritage site. Over a period of time establishing NDBR has invited conficts between the local people and reserve authorities on the management approaches and utilization criteria of the natural resources, especially banning the traditional bio-resource collection rights of local community, expeditions, trekking, and other anthropogenic activities in the core zones. The present study aims to understand and analyze the various people - park conflicts, and also to suggest ways to mitigate such conflicts in view of biodiversity conservation and improvement of economic status of local people by promoting eeotourism. With this view the study further discusses the various aspects of eeotourism, its pros and cons, and the avenues of developing appropriate strategies for promotion of ecotourism in buffer zone areas of NDBR.

关键词： Eeo-tourism Indian Himalaya NandaDevi Biosphere Reserve Nature conservation People-park conflicts

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Performance assessment of aged binder rejuvenated with Polanga oil

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Journal of Traffic and Transportation Engineering(English Edition) 2019年第6期6卷 608-620页

作者： Sujit Kumar Pradhan Umesh chandra Sahoo School of Infrastructure Indian Institute of Technology BhubaneswarOdisha 752050India

Presently,there is a necessity of increasing the reclaimed asphalt pavement(RAP)content in recycling of asphalt pavements to save material cost,preserve energy and protect the environment and efforts are being made to utilize 100%RAP in the *** binder is usually stiff due to oxidation and loss of *** addition of high amount of RAP to the asphalt mix,may make it prone to fatigue *** to this reason,rejuvenators are added to restore some of the physical and chemical properties for desired performance of the *** this study,a locally available non-edible oil known as Polanga oil(biological name:Calophyllum inophyllum)has been explored as rejuvenator to study its effect on performance of the aged *** binder prepared in the laboratory using the Pressure Aging Vessel(PAV)and binder extracted from the RAP collected from a nearby source were used in this study for *** binder and RAP binder mixed with the rejuvenator at varying *** rheological characterizations in terms of flow,rutting,fatigue and creep recovery of rejuvenated PAV aged&RAP binders were carried out using a dynamic shear rheometer(DSR)to determine the optimum dosage of the *** was observed that,5 percent of Polanga oil is able to divulge the desirable rheological properties of the rejuvenated binder.

关键词： Virgin bitumen Reclaimed asphalt pavement Rejuvenator Polanga oil Aged bitumen Rheology

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Electro-osmotic flow of a second-grade fluid in a porous microchannel subject to an AC electric field

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Journal of Hydrodynamics 2013年第2期25卷 309-316页

作者： MISRA J. C. chandra S. Department of Mathematics Institute of Technical Education and Research Siksha O Anusandhan University Department of Physics Sabang S. K. Mahavidyalaya Vidyasagar University

Studies on electro-osmotic flows of various types of fluids in microchannel are of great importance owing to their multifold applications in the transport of liquids, particularly when the ionized liquid flows with respect to a charged surface in the presence of an external electric field. In the case of viscoelastic fluids, the volumetric flow rate differs significantly from that of Newtonian fluids, even when the flow takes place under the same pressure gradient and the same electric field. With this end in view, this paper is devoted to a study concerning the flow pattern of an electro-osmotic flow in a porous microchannel, which is under the action of an alternating electric field. The influence of various rheological and electro-osmotic parameters, e.g., the Reynolds number, Debye-Huckel parameter, shape factor and fluid viscoelasticity on the kinematics of the fluid, has been investigated for a secondgrade viscoelastic fluid. The problem is first treated by using analytical methods, but the quantitative estimates are obtained numerically with the help of the software MATHEMATICA. The results presented here are applicable to the cases where the channel height is much greater than the thickness of the electrical double layer comprising the Stern and diffuse layers. The study reveals that a larger value of the Debye-Huckel parameter creates sharper profile near the wall and also that the velocity of electro-osmotic flow increases as the permeability of the porous microchannel is enhanced. The study further shows that the electro-osmotic flow dominates at lower values of Reynolds number. The results presented here will be quite useful to validate the observations of experimental investigations on the characteristics of electro-osmotic flows and also the results of complex numerical models that are necessary to deal with more realistic situations, where electro-osmotic flows come into the picture, as in blood flow in the micro-circulatory system subject to an elect

关键词： electrical double layer Debye length second-grade fluid Ionic energy

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Transport hindrances with electrodialytic recovery of citric acid from solution of strong electrolytes

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Chinese Journal of Chemical Engineering 2018年第2期26卷 278-292页

作者： Anusha chandra Jogi Ganesh Dattatreya Tadimeti Sujay Chattopadhyay Department of Polymer and Process Engineering.IIY Roorkee Saharanpur Campus Saharanpur 247001.India Department of Mechanical Engineering Swarnandhra College of Engineering and Technology Seetammpuram 534280.India

Electrodialytic （ED） recovery of citric acid （CA） in the presence/absence of strong electrolytes （NaCl, CaCl2 and Feel3） was separately analyzed under different process conditions. Recovery effectiveness was quantitatively estimated from current efficiency values. Efficiency attained optimum value with both flow rate and potential applied, while a monotonic rise was noted with temperature which got lowered beyond 0.1 tool. L 1 feed concentration. 40% drop in efficiency was recorded in the presence of strong electrolytes （Noel, CaCl2 and Feel3） in feed relative to their presence in concentrate. Severe transport hindrance and efficiency loss were attributed to adsorption and allied physicochemical changes occurred with anion/cation exchange membranes （AEM/CEM） and these were confirmed through contact angle/Chronopotentiometry/AFM/EDX. Sluggish potential rise （Galvanostatic mode） in Chronopotentiometric analysis indicated diffusion limiting transport of organic acids influenced AEM resistance. XRD and EDX analysis indicated the presence of salt hydrates/ions （Ca2＋/Fe3＋） over CEM justifying the resistance buildup due to adsorption of multivalent metal ion（s） and salts.

关键词： Electrodialysis Adsorption Electrolytes Recovery Chronopotentiometry AFM

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ON SOME GENERALIZED DIFFERENCE PARANORMED SEQUENCE SPACES ASSOCIATED WITH MULTIPLIER SEQUENCE DEFINED BY MODULUS FUNCTION

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Analysis in Theory and Applications 2011年第1期27卷 21-27页

作者： Binod chandra Tripathy Prabhat chandra Institute of Advanced Study in Science and Technology Patna University

In this article we introduce the paranormed sequence spaces （f,A, Am,p）, c0（f,A,Am,p） and L00（f,A, Am,p）, associated with the multiplier sequence ∧ = （hk）, defined by a modulus function f. We study their diff... 详细信息

关键词： paranorm solid space symmetric space difference sequence modulus function multiplier seuence

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Improvising the Self-Healing Capabilities of Concrete Using Different Pozzolanic Materials and Crystalline Admixtures

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Journal of Wuhan University of Technology(Materials Science) 2022年第3期37卷 429-439页

作者： A Ravitheja T chandra Sekhara Reddy C Sashidhar SVR Engineering College AyyalurNandyalKurnoolAndhra PradeshIndia Civil Engineering G Pulla Reddy Engineering CollegeKurnoolAPIndia Jawaharlal Nehru Technological University AnantapurIndia

To analyse the self-healing capacities in terms of mechanical performance of the pozzolanic materials,such as,fly ash,metakaolin and silica fume and crystalline ***-cracked concrete cubes with about 0.05 mm width were exposed to four different environmental conditions at different exposure times in order to determine the effect of temperature and water availability on the self-healing *** the exposure,the control and tested concrete cubes were evaluated for regained strength,void reduction,corrosion inhibition,damp proofing,relative impermeability and *** samples with SF10CA have better cementitious filling and low percentage of voids and water absorption.

关键词： crystalline admixtures pozzolanic materials self-healing

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Electro-magnetohydrodynamic Flow of Biofluid Induced by Peristaltic Wave： A Non-newtonian Model

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Journal of Bionic Engineering 2016年第3期13卷 436-448页

作者： Gopal chandra Shit Nayan Kumar Ranjit Aniruddha Sinha Department of Mathematics Jadavpur University Kolkata - 700032 India Yogoda Satsanga Palpara Mahavidyalaya Purba Medinipur - 721458 India

This article aims to develop a mathematical model for peristaltic transport of magnetohydrodynamic flow of biofluids through a micro-channel with rhythmically contracting and expanding walls under the influence of an applied electric field. The couple stress fluid model is considered to represent the non-Newtonian characteristics ofbiofluids. The velocity slip condition at the channel walls is taken into account because of the hyclrophilic/hydrophobic interaction with negatively charged walls. The essential features of the electromagnetohydrodynamic flow of biofluid through micro-channels are clearly highlighted in the variations of the non-dimensional parameters of the physical quantities of interest such as the velocity, wall shear stress, pressure gradient, pressure rise per wave length, frictional force at the channel walls and the distribution of stream function. It reveals that the flow ofhiofluid is appreciably influenced by the sufficient strength of externally applied magnetic field and electro-osmotic parameter. The velocity slip condition reduces the frictional force at the channel wall. Moreover, the formation of the trapping bolus strongly depends on electro-osmotic parameter and magnetic field strength.

关键词： peristaltic transport couple stress fluid magnetohydrodynamics electro-osmosis

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Wind pollination in Pinus roxburghii

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Progress in Natural Science:Materials International 2007年第1期17卷 32-38页

作者： Vinod Prasad KHANDURI chandra Mohan SHARMA Department of Forestry Mizoram University Aizawl(Mizoram)India Department of Forestry HNB Garhwal University Srinagar Garhwal-246 174(Uttaranchal)India

Stigmatic pollen load and pollen concentration in the air were studied in the natural population of Pinus roxburghii at Ashtavakra (900 m asl), in the Pauri forest division of Garhwal Himalaya, India. The results reflect diurnal pollen occurrence in P. roxburghii , with the strong significant correlations between pollen concentrations in the air and wind speed, air temperature and relative air humidity. A significant correlation was also observed between microsporangium dehiscence and pollen occurrence in the air. The maximum concentration of pollen grains in the air and higher rates of pollen deposition onto the megasporophylls were between 12 pm and 16 pm of the day, which conforms the best time for pollination in a day in P. roxburghii. The receptivity of Ovulate strobili varied from 3 to 5 days, however, the bagged strobili remained receptive up to 6 days.

关键词： ovulate strobili pollen cones pollination receptivity wind speed P. roxburghii.

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MOLECULAR DYNAMICS SIMULATION OF POLYMER/CARBON NANOTUBE COMPOSITES

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Acta Mechanica Solida Sinica 2015年第4期28卷 409-419页

作者： Sumit Sharma Rakesh chandra Pramod Kumar Navin Kumar Department of Mechanical Engineering Dr.B.R.Ambedkar National Institute of Technology School of Mechanical Materials & Energy Engineering (SMMEE) Indian Institute of Technology

In this paper, we present classical molecular dynamics （MD） simulations of model polymer/CNT composites constructed by embedding a single wall （10,10） CNT into two different amorphous polymer matrices： poly（methyl methacrylate） and poly{（m-phenylene-vinylene）-co- [（2,5-dioctoxy-p-phenylene） vinylene]}, respectively, with different volume fractions. The simulation results support the idea that it is possible to use CNTs to mechanically reinforce an appropri- ate polymer matrix, especially in the longitudinal direction of the nanotube. The comparison of the simulation results with the macroscopic rule-of-mixtures for composite systems showed that for strong interfacial interactions, there can be large deviations of the results from the rule-of- mixtures. In order to verify this study, results obtained have been compared with those given by Elliott and Han （2007）.

关键词： nano-structures elasticity mechanical properties computational modeling

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