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Hybrid silver nanoparticles:Modes of synthesis and various biomedical applications

Electron 2024年第2期2卷 196-218页

作者： priyanka singh Shivang singh Balaji Maddiboyina SaiKrishna Kandalam Tomasz Walski Raghvendra A.Bohara Centre for Interdisciplinary Research D.Y.Patil Educational SocietyKolhapurIndia Department of Internal Medicine Rauta Hospital Pvt.LtdGaighatUdayapurNepal Department of Medical and Scientific Communications Scientific Writing ServicesFreyr Global Regulatory Solutions&ServicesHyderabadTelanganaIndia INSERM U 1066 ‘Micro et Nanomédecines Biomimétiques-MINT’AngersFrance UniversitéAngers UMR-S1066AngersFrance Department of Biomedical Engineering Wroclaw University of Science and TechnologyWroclawPoland University of Galway

In the present day,there is a growing trend of employing new strategies to synthesize hybrid nanoparticles,which involve combining various functionalities into a single nanocomposite *** modern methods differ significantly from the traditional classical approaches and have emerged at the forefront of materials *** fabrication of hybrid nanomaterials presents an unparalleled opportunity for applica-tions in a wide range of areas,including therapy to *** focus of this review article is to shed light on the different modalities of hybrid nanoparticles,providing a concise description of hybrid silver nano-particles,exploring various modes of synthesis and classification of hybrid silver nanoparticles,and highlighting their ***-tionally,we discussed core-shell silver nanoparticles and various types of core and shell combinations based on the material category,such as dielectric,metal,or *** two primary classes of hybrid silver nanoparticles were also ***,various hybrid nanoparticles and their methods of synthesis were discussed but we emphasize silica as a suitable candidate for hybridization alongside metal *** choice is due to its hydrophilic surface qualities and high surface charge,which provide the desired repulsive forces to minimize aggregation between the metal nanoparticles in the liquid *** shell encapsulation also provides chemical inertness,robustness and the adaptability to the desired hybrid ***,among all the materials used to coat metal nanoparticles;silica is highly approved.

关键词： biomedical applications hybrid silver nanoparticles polyvinylpyrrolidone silica shell surface enhanced Raman spectroscopy

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Wastewater treatment using Fe-doped perovskite manganites by photocatalytic degradation of methyl orange,crystal violet and indigo carmine dyes in tungsten bulb/sunlight

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稀土学报:英文版 2023年第9期41卷 1311-1322,I0002页

作者： Brajendra singh priyanka singh Saiqua Siddiqui Divyanshu singh Mukul Gupta Materials Chemistry Lab Centre of Material SciencesUniversity of AllahabadPrayagraj21002India UGC-DAE Consortium for Scientific Research University CampusKhandwa Road Indore452001India

We documented(ⅰ) the decolorization of wastewater in visible light,which contains methyl orange,crystal violet and indigo carmine dyes,using La_(0.7)Sr_(0.3)Mn_(1-x)Fe_(x)O_(3)(x=0.0,0.05,0.1 and 0.5) manganites and(ⅱ) efficient separation of photocatalysts from water using magnetic *** ceramic photocatalysts were sintered at 1050℃ for 12 *** were characterized by X-ray diffraction(XRD),soft X-ray absorption spectroscopy(SXAS),Fourier transform infrared spectroscopy(FTIR) and UV-visible diffuse reflectance spectroscopy(DRS).SXAS studies show the presence of Mn(Mn^(3+)/Mn^(4+)) and Fe(Fe^(3+)/Fe^(4+)) mixes valences in Fe-doped *** band gap is found in visible light range for La_(0.7)Sr_(0.3)Mn_(1-x)Fe_(x)O_(3)(x=0.0,0.05,0.1) ***_(0.7)Sr_(0.3)MnO_(3) degrades 94.6% methyl orange in7 min,81.9% crystal violet in 10 min and 99.1% indigo carmine in 5 ***_(0.7)Sr_(0.3)Mn_(0.9)Fe_(0.1)O_(3) degrades the 92.6% methyl orange dye solution in 9 min,94.8% crystal violet in 25 min and 97.1% indigo carmine in3 *** and Fe doped manganites can be separated in 60 s from wastewater.

关键词： Synchrotron X-ray absorption Dye degradation Magnetic separation Mixed valences Rare earths Wastewater treatment

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Exogenous Peroxidase Mitigates Cadmium Toxicity, Enhances Rhizobial Population and Lowers Root Knot Formation in Rice Seedlings

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Rice science 2021年第2期28卷 166-177页

作者： priyanka singh Chitra POKHARIA Kavita SHAH Department of Biochemistry Faculty of ScienceBanaras Hindu UniversityVaranasi 221005India Environmental Biotechnology Laboratory Department of Environment and Sustainable DevelopmentInstitute of Environment and Sustainable DevelopmentBanaras Hindu UniversityVaranasi 221005India

Soil cadmium (Cd) causes toxicity and oxidative stress, alters biochemical processes and rootknot formation in rice. Irrigation of exogenous peroxidase (POX) together with its co-substrate H2O2(POXRice + H2O2), is likely to have protective effect upon the biochemical and nodular changes in ricegrown in Cd-rich soil. Exposure to Cd concentration of 1.00 mg/L increased oxidative stress, loss of cellviability, electrolyte leakage and root knot formation, whereas it significantly lowered the chlorophyll leveland rhizobium growth in rice. Irrigation of exogenous POXRice + H2O2 to Cd-stressed rice seedlingsreversed the Cd-induced alterations in rice to levels similar in control (non-stressed) seedlings. Resultsprovided strong evidence of exogenous POXRice + H2O2-mediated reversal and restoration of physiologicaland biochemical processes as well as increased resistance of rice seedlings to root knot *** with POXRice + H2O2 appeared to contribute towards bringing normoxic conditions in the otherwisehypoxic soil environment by enhancing the O2 in pot-experiments due to reduced Cd uptake, enhancedmineral homeostasis of essential elements viz. P, Fe, Mo, Mg and Mn for maintenance of root architecturedamaged by lipid peroxidation and reduction in oxidative stress by reducing Cd-induced reactive oxygenspecies generation. Therefore, the mitigation of Cd-toxicity in rice through this novel approach appeared tobe a promising mode to limit Cd-uptake, modulate protective and tolerance mechanisms for sustainablerice yield in Cd-contaminated rice-croplands and prevent nematode attack in rice, however, more detailedstudies are needed prior to large scale applications.

关键词： cadmium peroxidase rice rhizobium root knot reactive oxygen species antioxidant enzyme

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Extracellular synthesis of silver nanoparticles by Pseudomonas sp. THG-LS1.4 and their antimicrobial application

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Journal of Pharmaceutical Analysis 2018年第4期8卷 258-264页

作者： Hina singh Juan Du priyanka singh Tae Hoo Yi Department of Oriental Medicine Biotechnology College of Life Science Kyung Hee University Global Campus College of Food and Bioengineering Zhengzhou University of Light Industry Henan Province Collaborative Innovation Center for Food Production and Safety

Silver nanoparticles（Ag NPs） are known to have bacteriostatic and bactericidal effects. The present study highlights the extracellular synthesis of Ag NPs and its antibacterial properties. The Ag NPs were synthesized using Pseudomonas sp. THG-LS1.4 strain which had been isolated from soil. The Ag NPs were characterized by field emission-transmission electron microscopy（FE-TEM）, X-ray diffraction（XRD）,Fourier transform-infrared（FT-IR） spectroscopy, and particle size distribution（DLS）. The Ag NPs displayed maximum absorbance at 412 nm and were irregular in shape ranging from 10 to 40 nm. The XRD spectroscopy results demonstrated the crystalline nature of nanoparticles. The Ag NPs showed antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Candida tropicalis, Vibrio parahaemolyticus, Escherichia coli and Pseudomonas aeruginosa. Furthermore, the Ag NPs were also evaluated for their increased antibacterial activities with various antibiotics against Escherichia coli, Pseudomonas aeruginosa and Salmonella enterica. Additionally, Ag NPs showd biofilm inhibition activity. The biosynthesized Ag NPs were found to be a potent agent against tested pathogens. More importantly, we highlight the applications of Ag NPs as an antimicrobial agent.

关键词： Extracellular synthesis Silver nanoparticles Pseudomonas sp.THG-LS1.4 Antimicrobial activity

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Discount pricing policy for deteriorating items under preservation technology cost and shortages

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Journal of Management Analytics 2020年第4期7卷 649-671页

作者： Anubhav Namdeo Uttam Kumar Khedlekar priyanka singh Department of Mathematics and Statistics Dr.Hari Singh Gour UniversitySagarIndia

This paper presents an inventory model with a constant rate of deterioration of the product,and shortages are allowed at the end of the *** stock-dependent and price-sensitive demand have been considered with a policy of providing price discount to uplift the market *** technology is applied to preserve the items from *** objective of this model is to maximize the total profit function by finding the optimal replenishment time,the optimal preservation technology investment and the optimal ***,we have shown that the total profit is a concave function of the replenishment time and preservation technology *** in pricing may be offered at a time of festival,season breaks down,lockdown and clearance of stock,before introducing a new product with up-gradations,*** examples and graphical analysis are provided to explain the *** discount policy could help any business organizations for smooth running of the business and obtain respective optimal profit.

关键词： inventory stock-dependent and price-sensitive demand preservation technology deterioration discount replenishment cycle

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A comprehensive review on bioactive peptides derived from milk and milkproducts of minor dairy species

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Food Production, Processing and Nutrition 2021年第1期3卷 11-31页

作者： Snigdha Guha Heena Sharma Gaurav Kr Deshwal priyanka singh Rao Department of Food Science and Technology University of Nebraska-LincolnLincolnNE 68588-6205USA Food Technology Laboratory Dairy Technology DivisionNational Dairy Research Institute(ICAR-NDRI)KarnalHaryana 132001India Dairy Chemistry and Bacteriology Section Southern Regional Station-National Dairy Research InstituteBengaluru 560030India

Milk from different species has been exploited for the isolation of various functional ingredients for *** of the source,milk is considered as a complete food,as it provides essential nutrients required by the human *** and their fractions are valuable sources of bioactive peptides that might exert a health beneficial role in the human body such as immune-modulation,antioxidant activity,ACE-inhibitory activity,anti-neoplastic,anti-microbial,*** milk,bioactive peptides may either be present in their natural form or released from their parental proteins due to enzymatic *** increasing interest in bioactive peptides among researchers has lately augmented the exploration of minor dairy species such as sheep,goat,camel,mithun,mare,and *** to cow,milk from minor dairy species have also been proven to be healthier from infancy to older age owing to their higher digestibility and other nutritive ***,realizing the significance of milk from such species and incentivized interest towards the derivatization of bioactive peptides,the present review highlights the significant research achievements on bioactive peptides from milk and milk products of minor dairy species.

关键词： Milk protein Bioactive peptides Camel Goat Sheep Donkey

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Current therapeutic strategies for inflammation following traumatic spinal cord injury

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Neural Regeneration Research 2012年第23期7卷 1812-1821页

作者： priyanka L.singh Nitin Agarwal James C.Barrese Robert F.Heary Department of Neurological Surgery UMDNJ-New Jersey Medical SchoolNewarkNJ 07101-1709USA Reynolds Family Spine Laboratory NewarkNJ 07101-1709USA

Damage from spinal cord injury occurs in two phases-the trauma of the initial mechanical insult and a secondary injury to nervous tissue spared by the primary *** from damage sustained as a result of direct trauma to the spinal cord,the post-traumatic inflammatory response contributes significantly to functional motor deficits exacerbated by the secondary *** the detrimental aspects of the inflammatory response is a promising strategy to potentially ameliorate the secondary injury,and promote significant functional *** review details how the inflammatory component of secondary injury to the spinal cord can be treated currently and in the foreseeable future.

关键词： acute spinal cord injury inflammation treatment secondary injury neuroprotective hypothermia erythropoietin estrogen etanercept rolipram

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Molecular characterization of DENV-3 circulating during the post-monsoon period of 2013–14 in Delhi, India

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Virologica Sinica 2015年第6期30卷 464-469页

作者： Pankaj Sharma Veena Mittal Mala Chhabra Roop Kumari priyanka singh Dipesh Bhattacharya Srinivas Venkatesh Arvind Rai Division of Zoonosis National Centre for Disease Control Centre for Medical Entomology and Vector Management National Centre for Disease Control Division of Biotechnology National Centre for Disease Control

Dear Editor,Dengue infection is one of the emerging concerns for public health on a global *** the past few years,dengue transmission has increased in the Americas,the western Pacific and southeast *** magnitude,distribution,and clinical severity of dengue outbreaks have been an alarming signal in the southeast Asia *** outbreaks have been reported in countries in

关键词： southeast dengue India circulating monsoon in Delhi severity sequenced Major emerging

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Emergence of taurine as a therapeutic agent for neurological disorders

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Neural Regeneration Research 2024年第1期19卷 62-68页

作者： Ashok Jangra priyanka Gola Jiten singh Pooja Gond Swarnabha Ghosh Mahesh Rachamalla Abhijit Dey Danish Iqbal Mehnaz Kamal Punya Sachdeva Saurabh Kumar Jha Shreesh Ojha Dinesh Kumar Niraj Kumar Jha Hitesh Chopra Shing Cheng Tan Department of Pharmaceutical Sciences Central University of HaryanaMahendergarhHaryanaIndia Department of Biology University of SaskatchewanSaskatoonSKCanada Department of Life Sciences Presidency UniversityKolkataWest BengalIndia Department of Health Information Management College of Applied Medical SciencesBuraydah Private CollegesBuraydahSaudi Arabia Department of Pharmaceutical Chemistry College of PharmacyPrince Sattam Bin Abdulaziz UniversityAl-KharjSaudi Arabia GloNeuro Vishwakarma RoadNoidaIndia Department of Biotechnology School of Engineering&Technology(SET)Sharda UniversityGreater NoidaUttar PradeshIndia Department of Pharmacology and Therapeutics College of Medicine and Health SciencesUnited Arab Emirates UniversityAl AinUnited Arab Emirates School of Bioengineering&Biosciences Lovely Professional UniversityPhagwaraIndia Department of Biotechnology School of Applied&Life Sciences(SALS)Uttaranchal UniversityDehradunIndia Chitkara College of Pharmacy Chitkara UniversityPunjabIndia UKM Medical Molecular Biology Institute Universiti Kebangsaan MalaysiaKuala LumpurMalaysia

Taurine is a sulfur-containing,semi-essential amino acid that occurs naturally in the *** alternates between inflammation and oxidative stress-mediated injury in various disease *** part of its limiting functions,taurine also modulates endoplasmic reticulum stress,Ca^(2+)homeostasis,and neuronal activity at the molecular *** effectively protects against a number of neurological disorders,including stro ke,epilepsy,cerebral ischemia,memory dysfunction,and spinal cord *** various therapies are available,effective management of these disorders remains a global *** 30 million people are affected *** design of taurine fo rmation co uld lead to potential drugs/supplements for the health maintenance and treatment of central nervous system *** general neuroprotective effects of taurine and the various possible underlying mechanisms are discussed in this *** article is a good resource for understanding the general effects of taurine on various *** the strong evidence for the neuropharmacological efficacy of taurine in various experimental paradigms,it is concluded that this molecule should be considered and further investigated as a potential candidate for neurotherapeutics,with emphasis on mechanism and clinical studies to determine efficacy.

关键词： antioxidant epilepsy γ-amino butyric acid neurodegenerative disorders neuroprotection oxidative stress spinal cord injury taurine

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印度春季角结膜炎患儿血清维生素D的变化

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国际眼科杂志 2020年第7期20卷 1126-1131页

作者： priyanka singh Smriti Dabas Anuj Mehta L.Sarkar Vardhman Mahavir医科大学&Safdarjung医院眼科印度新德里110029

目的:评估印度人群中春季角结膜炎(VKC)患者维生素D水平。方法:研究共纳入30名非特应性健康儿童和30名VKC儿童。比较两组间的血清维生素D水平和户外活动时间(P<0.05)。结果:VKC组血清维生素D平均水平(19.17±10.76 ng/mL)明显低于对照组... 详细信息

目的:评估印度人群中春季角结膜炎(VKC)患者维生素D水平。方法:研究共纳入30名非特应性健康儿童和30名VKC儿童。比较两组间的血清维生素D水平和户外活动时间(P<0.05)。结果:VKC组血清维生素D平均水平(19.17±10.76 ng/mL)明显低于对照组(31.19±9.09 ng/mL)(P=0.0003)。43.33%的患者维生素D缺乏(10~20 ng/mL),而20%的VKC患者严重缺乏(<10 ng/mL)。维生素D的缺乏与VKC的严重程度相关(P<0.02)。VKC组户外时间为1.07±0.76h/每天,健康组户外时间为2.08±0.72h/每天(P<0.0001),与血清25(OH)D3水平显著相关(r=0.478,P<0.001)。结论:研究表明,VKC患儿的血清维生素D水平明显低于健康儿童,与户外活动时间有关。VKC的严重程度也与维生素D缺乏的严重程度相关,由此得出维生素D在维持眼表健康中发挥重要作用。

关键词：春季角结膜炎维生素D缺乏儿童

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