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National trends in total hip arthroplasty for traumatic hip fractures:An analysis of a nationwide all-payer database

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World Journal of Orthopedics 2020年第1期11卷 18-26页

作者： Anthony J Boniello Alexander M Lieber Kevin Denehy priscilla cavanaugh Yehuda E Kerbel Andrew Star Rothman Orthopaedic Institute Thomas Jefferson UniversityPhiladelphiaPA 19107United States Drexel University College of Medicine PhiladelphiaPA 19123United States Bluegrass Orthopaedics LexingtonKY 40509United States Deparment of Orthopaedics Hospital of University of PennsylvaniaPhiladelphiaPA 19104United States

BACKGROUND Hemiarthroplasty(HA)has traditionally been the treatment of choice for elderly patients with displaced femoral neck *** treatment for younger,ambulatory patients is not as *** hip arthroplasty(THA)has been increasingly utilized in this population however the factors associated with undergoing HA or THA have not been fully *** To examine what patient characteristics are associated with undergoing THA or *** determine if outcomes differ between the *** We queried the Nationwide Inpatient Sample(NIS)for patients that underwent HA or THA for a femoral neck fracture between 2005 and *** NIS comprises a large representative sample of inpatient hospitalizations in the United *** Classifications of Disease,Ninth Edition(ICD-9)codes were used to identify patients in our *** variables,hospital characteristics,payer status,medical comorbidities and mortality rates were compared between the two *** logistic regression analysis was then performed to identify independent risk factors of treatment *** Of the total 502060 patients who were treated for femoral neck fracture,51568(10.3%)underwent THA and the incidence of THA rose from 8.3%to 13.7%.Private insurance accounted for a higher percentage of THA than *** increased most in urban teaching hospitals relative to urban non-teaching *** length of stay(LOS)was longer for *** mean charges were less for HA,however charges decreased steadily for both *** had a higher mortality rate,however,after adjusting for age and comorbidities HA was not an independent risk factor for ***,private insurance was an independent predictor for treatment with *** There has been an increase in the use of THA for the treatment of femoral neck fractures in the United States,most notably in urban *** and THA are decreasing in total charges and LOS.

关键词： Hip fracture Total hip arthroplasty Hemiarthroplasty Cost Length of stay National Inpatient Sample

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NOD2: Ethnic and geographic differences

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World Journal of Gastroenterology 2006年第23期12卷 3673-3677页

作者： Juleen cavanaugh Medical Genetics Research Unit ANU Medical School at the Canberra HospitalAustralian National UniversityWodenACT 2606Australia

Investigations into the inheritance of the three risk alleles R702W, G908R and 1007 fsInsC in NOD2 associated with susceptibility to Crohn＇s disease have demonstrated a remarkable amount of heterogeneity across ethnicities and populations, with regional variation across Europe for example, suggesting local founder effects. In nonCaucasian populations Crohn＇s disease continues to increase in incidence but this increase appears not to be a consequence of variation in NOD2, further advancing the accumulating evidence for other susceptibility loci. Frequencies of the known alleles are compared across populations in health and disease and evidence for additional alleles in NOD2 is reviewed. Based on its position on chromosome 16 coincident with some other autoimmune disease susceptibility Iocalizations, research has targeted NOD2 variation as the potential cause of other autoimmune disorders. While these investigations have mostly returned negative findings, two diseases, Blau Syndrome and Graft versus Host Disease, have been shown to be caused by risk alleles in NOD2. As is frequent in complex disease investigations, some results await validation, but the identification of NOD2 and the differences within and across population raises intriguing questions about the population genetics of the variation at this locus.

关键词： NOD2 Crohn's disease Inflammatory boweldisease Ethnicities

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Discussion of prior-based Bayesian information criterion(PBIC)by ***,James ***,Woncheol Jang,Surajit Ray,Luis ***,and Ingmar Visser

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Statistical Theory and Related Fields 2019年第1期3卷 32-34页

作者： Ryan A.Peterson Joseph E.cavanaugh Department of Biostatistics University of IowaIowa CityIAUSA

We congratulate the authors on their innovative and illuminating *** paper should not only lead to more refined and defensible applications of the Bayesian information criterion(BIC)through their proposed variants,but... 详细信息

关键词： criterion refined innovative

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The Application of the LDL Principle

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World Journal of Cardiovascular Diseases 2016年第5期6卷 109-125页

作者： David S. Schade Brendan cavanaugh Barry Ramo R. Philip Eaton Division of Endocrinology DoIM School of Medicine University of New Mexico Albuquerque NM USA New Mexico Heart Institute Albuquerque NM USA

The LDL Principle has recently been invoked to describe the observation that lowering the LDL cholesterol (by whatever means) results in a lowering of atherosclerotic cardiovascular events. The scientific basis of the LDL Principle dates back to the discovery that the LDL receptor is the prime determinant of the circulating LDL-c concentration. Since that time, major advances have been made at both the basic and clinical science level in our understanding of the pathogenesis and reversal of atherosclerosis. The incorporation of atherogenic lipoproteins plus inflammatory mediators into plaque formation permits the targeted intervention into preventing plaque rupture. In addition, genetic studies identifying individuals with unique phenotypes of either abnormally high or low LDL-c concentrations have provided insight into possible therapeutic modalities that have recently provided the physician with the tools necessary to apply the LDL Principle to achieve reversal of atherosclerosis. The epidemic of atherosclerotic cardiovascular disease has resulted in numerous randomized controlled intervention trials in an attempt to identify approaches to reduce ASCD morbidity and mortality. Recently published data indicate that circulating LDL-c levels of 50 mg/dl or less are not only physiologic at birth but also effective in greatly reducing cardiovascular disease. In addition, the recent availability of two PCSK9 inhibitors provides the primary care physician with the possibility of achieving this low level of LDL-c even in statin intolerant patients. The widespread availability of the coronary artery calcium scan plus the inclusion of traditional cardiovascular risk factors in risk assessment has enabled the physician to readily identify asymptomatic individuals at high risk for cardiovascular events. Aggressively applying the LDL Principle to these individuals has the potential of greatly reducing cardiovascular mortality. This review will document the scientific basis for

关键词： LDL Principle Atherosclerosis Myocardial Infarction Atherosclerosis Reversal LDL Cholesterol

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最后之舞──记美国椰林夜总会特大火灾

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时代消防 2000年第1期 32-37页

作者： Casey cavanaugh 卞青

五位当事人永远忘不了１９４２年１１月２８日的那个夜晚……

关键词：美国椰林夜总会特大火灾消防安全

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成为你想成为的人

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英语沙龙（初级版） 2008年第3期 16-17页

作者： Brian cavanaugh 张晨

这是一个令人难以置信的真实故事:从小身体不好,曾经得过小儿麻痹、猩红热和双侧鲁道夫凭着超人的毅力战胜病魔,赢得了三枚奥运会金牌。威尔玛鲁道夫的故事告诉我们:乐观些,任何时候都别放弃梦想,这样才能成为我们想成为的人。.

关键词：奥运会金牌玛鲁道夫威尔尔玛双侧肺炎 catch mother wonder notion

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EMD的首批6000马力内燃机车投入商业运营

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国外内燃机车 1998年第12期 29-31页

作者： John N cavanaugh 王钧

美国GM公司EMD推出了SD90MAC型4700kW交流传动机车。本文介绍了EMD为SD90MAC型机车设计的16V265H型发动机及其增压器的主要技术参数和设计特点；评述了首批SD90MAC型机车的试验效果。

关键词：内燃机车设计技术参数结构 16V265H SD90MAC EMD 商业运营

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Innervation of cervical ventral facet joint capsule: Histological evidence

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World Journal of Orthopedics 2012年第2期3卷 10-14页

作者： Srinivasu Kallakuri Yan Li Chaoyang Chen John M cavanaugh Department of Biomedical Engineering Wayne State University818 W Hancock Detroit MI 48201 United States

AIM: To assess the presence of nerves in ventral facet joint capsules as facet capsules are generally implicated in neck ***: Twenty-four ventral cervical facet joint capsules were harvested from 3 unembalmed cadavers. Paraffin sections from these capsules were processed to identify neurofilament and substance P immunoreactive fibers. Nerve fiber presence was also verified by a silver impregnation ***: Neurofilament reactive fibers were observed in sections from 9 capsules. They were observed in areas with collagen fibers and areas with irregular connective tissue. Substance P reactive nerve fibers were found in sections from 7 capsules in similar areas. Silver impregnation also revealed the presence of nerve fibers. The nerve fibers were also found as bundles in the lateral margins of the capsule. A Pacinian corpuscle-like ending was also observed in ***: Nerve fibers revealed by neurofilament immunoreactivity and silver staining support innervation of the ventral aspect of the facet joint capsule. The presence of substance P reactive fibers supports the potential role of these elements in mediating pain. The presence of a Pacinian-like ending implicates a potential role in joint movement.

关键词： Cervical facet joint capsule Whiplash Nerve fibers Neurofilament Substance P Pain

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应用微机技术的遥控货物列车制动

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智慧轨道交通 1987年第3期 18-25页

作者： S.cavanaugh 王守恒

19世纪60年代北美许多铁路已达到了线路最大通过能力,载重货物列车在陡峭的上坡铁路上运行特别困难,因为车钩强度限制了增加列车长度和在列车头部增加多台机车。在列车尾部或列车中部插进补机,虽解决了短距离线路上的一些困难,但因人力... 详细信息

19世纪60年代北美许多铁路已达到了线路最大通过能力,载重货物列车在陡峭的上坡铁路上运行特别困难,因为车钩强度限制了增加列车长度和在列车头部增加多台机车。在列车尾部或列车中部插进补机,虽解决了短距离线路上的一些困难,但因人力和设备的使用效率低,提高了运输成本。在列车中编组无线电控制的机车组,可在不增加人力费用的情况下,使列车编组长

关键词：空气制动电磁阀控制台压力传感器紧急制动按钮电磁操作阀均衡风缸列车管

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交流牵引技术在北美货运机车中的应用

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国外铁道机车与动车 1987年第11期 10-21页

作者： S.D.cavanaugh 程永陆

本文叙述了加拿大太平洋铁路所作的交流牵引技术在北美货运机车应用中的性能评价工作。评述了导致1981年提出交流牵引发展计划的有关问题。对直流牵引与交流牵引的潜力进行了比较。介绍了改装到加拿大太平洋铁路的一台电传动内燃机车(CP... 详细信息

本文叙述了加拿大太平洋铁路所作的交流牵引技术在北美货运机车应用中的性能评价工作。评述了导致1981年提出交流牵引发展计划的有关问题。对直流牵引与交流牵引的潜力进行了比较。介绍了改装到加拿大太平洋铁路的一台电传动内燃机车(CP4744号)上的交流控制电路和硬件。整备试验之后,为了与一台基准的六轴直流传动机车进行粘着利用率的定量比较并测取牵引力和动力制动特性,又进行了大量的性能试验。考察了可靠性的提高和维修费的减少给生产率的提高和综合成本的降低带来的好处,进而详细讨论了交流牵引技术今后的发展方向。

关键词：铁路机车交流牵引逆变器动力制动牵引力生产率总重太平洋铁路电子器件行走力外力牵引电动机交流传动机车北美

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