检索结果-南通市图书馆

Correlation of transient elastography with hepatic venous pressure gradient in patients with cirrhotic portal hypertension: A study of 326 patients from India

引用

World Journal of Gastroenterology 2017年第4期23卷 687-696页

作者： Ashish Kumar Noor Muhammad Khan Shrihari Anil Anikhindi praveen Sharma Naresh Bansal Vikas Singla Anil Arora Institute of Liver Gastroenterologyand Pancreatico-Biliary SciencesGanga Ram Institute for Postgraduate Medical Education and ResearchSir Ganga Ram HospitalNew Delhi 110060India

AIMTo study the diagnostic accuracy of transient elastography (TE) for detecting clinically significant portal hypertension (CSPH) in Indian patients with cirrhotic portal *** retrospective study was conducted at the Institute of Liver, Gastroenterology, and Pancreatico-Biliary Sciences, Sir Ganga Ram Hospital, New Delhi, on consecutive patients with cirrhosis greater than 15 years of age who underwent hepatic venous pressure gradient (HVPG) and TE from July 2011 to May 2016. Correlation between HVPG and TE was analyzed using the Spearman’s correlation test. Receiver operating characteristic (ROC) curves were prepared for determining the utility of TE in predicting various stages of portal hypertension. The best cut-off value of TE for the diagnosis of CSPH was obtained using the Youden *** study included 326 patients [median age 52 (range 16-90) years; 81% males]. The most common etiology of cirrhosis was cryptogenic (45%) followed by alcohol (34%). The median HVPG was 16.0 (range 1.5 to 30.5) mmHg. Eighty-five percent of patients had CSPH. A significant positive correlation was noted between TE and HVPG (rho 0.361, P < 0.001). The area under ROC curve for TE in predicting CSPH was 0.740 (95%CI: 0.662-0.818) (P < 0.01). A cut-off value of TE of 21.6 kPa best predicted CSPH with a positive predictive value (PPV) of 93%.CONCLUSIONTE has a fair positive correlation with HVPG; thus, TE can be used as a non-invasive modality to assess the degree of portal hypertension. A cut-off TE value of 21.6 kPa identifies CSPH with a PPV of 93%.

关键词： Portal hypertension Cirrhosis Clinically significant portal hypertension Liver stiffness Transient elastography FibroScan

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization

引用

Signal Transduction and Targeted Therapy 2023年第3期8卷 905-907页

作者： Shao-bin Wang Yosuke Nagasaka Dionne Argyle Ayami Nagasaka praveen Yerramothu Bradley DGelfand Jayakrishna Ambati Center for Advanced Vision Science University of Virginia School of MedicineCharlottesvilleVAUSA Department of Ophthalmology University of Virginia School of MedicineCharlottesvilleVAUSA Department of Biomedical Engineering University of Virginia School of MedicineCharlottesvilleVAUSA Department of Pathology University of Virginia School of MedicineCharlottesvilleVAUSA Department of Microbiology Immunologyand Cancer BiologyUniversity of Virginia School of MedicineCharlottesvilleVAUSA

Dear Editor,Vascular endothelial growth factor-A(VEGFA,also known as VEGF)is a critical angiogenic factor that regulates the physiological and pathological blood vessel growth.1 Increased abundance of VEGF in the eye underlies many forms of aberrant ocular angiogenesis and resultant vision loss,including in neovascular age-related macular degeneration(nvAMD),proliferative diabetic retinopathy(PDR).

关键词： degeneration ocular release

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Anti-oxidant and anti-inflammatory activity of leaf extracts and fractions of Mangifera indica

引用

Asian Pacific Journal of Tropical Medicine 2013年第4期6卷 311-314页

作者： Mohan CG Deepak M Viswanatha GL Savinay G Hanumantharaju V Rajendra CE praveen D Halemani Department of Pharmacognosy Government College of PharmacyBangalore-560027 Department of Phytochemistry Natural Remedies PvtLtd.Bangalore-560 100 Department of Pharmacology PES College of PharmacyBangalore-560050 Deparment of Pharmaceutics Government College of PharmacyBangalore-560027 Drug Testing Laboratory Drugs Control DepartmentPalace roadBangalore-560001 Department of Pharmaceutics Government College of PharmacyBangalore-560 027

Objective:To evaluate the anti-oxidani and anti-inflammatory activity of leaf extracts and fractions of Mangifera indica in in vitro ***:In vitro DPPH radical scavenging activity and lipoxygenase（LOX） inhibition assays were used to evaluate the anti-oxidant and anti-inflammatory activities *** extract（MEMI）,successive water extract （SWMI） and ethyl acetate fraction（EMEMI）,n-butanol fraction（BMEMI） and water soluble fraction （WMEMI） of methanolic extract were evaluated along with respective reference standards. Results:In in ritro DPPH radical scavenging activity,the MEMI,EMEMI and BMEMI have offered significant antioxidant activity with IC50 values of 13.***.3.55 and 14.19μig/mL *** acid,a reference standard showed significant antioxidant activity with IC? value of 1.88 and found to be more potent compared to all the extracts and *** m vitro LOX inhibition assay,the MEMI,EMEMI and BMEMI have showed significant inhibition of LOX enzyme activity with IC50 values of 96.***.63.21 and 107.44μg/mL ***,reference drug Indometlhacin also offered significant inhibtion against LOX enzyme activity with IC50 of ***,MEMI was found to more potent than SWMI and among the fractions EMEMI was found to possess more potent antioxidant and anti-inflammatory ***:These findings suggest that the MEMI and *** possess potent anti-oxidani and anti-inflammatory activities in in vitro conditions.

关键词： Mangifera indica Lipoxygenase DPPH assay Antioxidants Anti-inflammatory

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of laser surface melting on surface integrity of Al-4.5Cu composites reinforced with SiC and MoS2

引用

Transactions of Nonferrous Metals Society of China 2020年第2期30卷 344-362页

作者： praveen Kumar BANNARAVURI Anil Kumar BIRRU Uday Shanker DIXIT Department of Mechanical Engineering Karunya Institute of Technology and ScienceCoimbatoreTamil Nadu 641114India Department of Mechanical Engineering National Institute of Technology ManipurImphal 795004India Department of Mechanical Engineering Indian Institute of Technology GuwahatiAssam 781039India

Two types of composites were prepared with Al-4.5Cu alloy as a matrix using stir casting *** was reinforced with 10wt.%of Si C and 2wt.%of *** other was reinforced with 10wt.%of Si C and 4wt.%of *** surfaces were remelted using a CO2 laser beam with an objective to study the influence of laser surface melting(LSM).The topography,microhardness,corrosion resistance and wear resistance of the laser melted surfaces were *** surface integrity after LSM was compared with as-cast *** enhanced the microhardness and wear resistance of the surface in each *** of the laser melted surface was low and corrosion resistance was ***,LSM can be conveniently applied to enhancing the surface integrity of the aluminium ***,there is an optimum laser specific energy,around 38 J/m^2 in this study,for obtaining the best surface integrity.

关键词： aluminium composites silicon carbide molybdenum disulfide laser surface melting microhardness corrosion resistance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Medicinal Plants: In Vitro Culture and Mass Production

Medicinal Plants: In Vitro Culture and Mass Production

引用

第一届全国化学工程与生物化工年会

作者： praveen Saxena Department of Plant Agriculture University of GuelphCanada

＜正＞ The international trade in medicinal plants and phytopharmaceuticalpreparations is a major force in the global economy and the demandis increasing in both developing and industrialized nations. However,numerous problems have arisen that have compromised the quality,safety, and efficacy of the products. The problems with the productionof medicinal plant products are due to a lack of solid scientificinformation about the unique physiology of medicinal plants that ismanifested in poor product quality. Issues that need to be addressed

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Association of Overt Diabetes Mellitus with the Non-CC but not the CC Genotype of Interleukin-28B in Hepatitis C Virus Infected Patients

引用

Journal of Clinical and Translational Hepatology 2016年第1期4卷 26-31页

作者： Ashish Kumar Varun Gupta praveen Sharma Naresh Bansal Vikas Singla Anil Arora Institute of Liver Gastroenterology & Panceatico-Biliary Sciences Sir Ganga Ram Hospital New Delhi India

Background:Interleukin-28B (IL-28B) polymorphism is an important predictor for hepatitis C virus (HCV) treatment *** IL-28b genotypes also influence other nontreatment related clinical parameters is ***:Patients with HCV-related chronic liver diseases who attended our department during 2012-2014 were retrospectively *** single nucleotide polymorphisms (SNPs) of rs12979860 (IL-28B) were correlated with various clinical *** also compared these parameters in patients with and without overt diabetes to identify possible ***:A total of 115 patients were included (median age 48,range 15-76 years;70% males).Overall,43/115(37%) patients had chronic hepatitis,while the remaining 72/115 (63%) had *** most common IL-28B genotype was CC,which was found in 53% of patients (61/115),while the remaining 47% were nonCC [CT 42% (48/115) and T-r 5% (6/115)].Clinical and laboratory parameters like Hb,white blood cell (WBC),platelets,bilirubin,transaminases,and albumin were similar in the CC and nonCC *** diabetes mellitus was present in 22% (25/115) of *** with nonCC genotype had significantly higher prevalence of overt diabetes mellitus than patients with CC genotype (31% [17/54] versus 13% [8/61];p < 0.05).When parameters were compared in patients with and without overt diabetes mellitus,only IL-28B and age were significantly associated with overt diabetes mellitus (p < 0.05).Conclusion:In HCV patients,overt diabetes mellitus was more commonly associated with the nonCC genotype of IL-28B than the CC *** of the T-allele of SNP rs12979860 were more likely to have insulin resistance than CC homozygotes,and this finding may explain the higher prevalence of diabetes in non-CC ***,an IL-28B test may be useful in patients of HCV in order to determine their likelihood of developing diabetes mellitus.

关键词： Chronic hepatitis C Diabetes mellitus Cirrhosis IL-28B Chronic liver disease Insulin resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pediatric and neonatal mechanical ventilation（Second Edition） 2

引用

2011年

作者： praveen Khilnani

Previous ed.: ***, 289 p. : ill. (some col.), [9] *** plates ; 24 cm. + 1 DVD-ROM (4 3/4 in.)

ISBN: (纸本)9789350252451

Previous ed.: ***, 289 p. : ill. (some col.), [9] *** plates ; 24 cm. + 1 DVD-ROM (4 3/4 in.)

关键词： Pediatric. Respiratory therapy.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Fibre-Reinforced Generalized Thermoelastic Medium under Hydrostatic Initial Stress

引用

Engineering（科研） 2011年第6期3卷 622-631页

作者： praveen Ailawalia Shilpy Budhiraja 不详

The present problem is concerned with the deformation of an infinite fibre-reinforced generalized thermoe-lastic medium with hydrostatic initial stress under the influence of mechanical force. The normal mode analysis is used to obtain the analytical expressions of the displacement components, force stress and temperature distribution. The numerical results are given and presented graphically for Green -Lindsay [4] theory of thermoelasticity. Comparisons are made in the presence and absence of hydrostatic initial stress and anisotropy.

关键词： Generalized Thermoelastic Hydrostatic Initial Stress Fibre-Reinforced Temperature Distribution Normal Mode Anisotropy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Projected Warming and Occurrence of Meteorological Droughts—Insights from the Coasts of South India

引用

American Journal of Climate Change 2015年第2期4卷 173-179页

作者： Dhanya praveen A. Ramachandran Centre for Climate Change and Adaptation Research Anna University Chennai India

The latest development in the climate change forecast, using regional climate models, made it possible to provide more detailed information on the future changes in the climatic variables in the face of global warming. The PRECIS, UK Met office Hadley Centre’s Regional Climate Model is being used in simulating the future climate corresponding to the IPCC-SRES A1B emission scenario for the period 2040-2070 with reference to the base line year 1970-2000 for coastal region of Thiruvallur, South India. The results indicated a significant increase in the mean maximum temperature, mean minimum temperature and a slight decrease in the precipitation over the study area. The outcomes of the IMD method of Percent Deviation analysis show that the Thiruvallur has witnessed moderate to mild droughts during the period 1970 to 2011. Moderate drought years were mainly 1974, 1980, 1982 and 1999 with -35.78%, -30.09%, -30.54%, -27.30% rainfall deviations respectively. SPI-12 is also employed to analyze the occurrence and severity of drought events in the past. The analysis revealed that the year 1974 with SPI value -2.05 was the extremely severe drought year on record during the period 1970-2011. The years 1982 (-1.7), 1980 (-1.67), 1999 (-1.48) were severe dry years. Pearson’s correlation analysis proved that both the outputs have significant positive correlation (0.05 level) with R2 value of 0.992. It is necessary to develop early warning systems and apt drought preparedness strategies to cope with this natural hazard.

关键词： Global Warming Drought Standardised Precipitation Index Climate Change Regional Climate Modelling Impacts

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Imaging-based algorithmic approach to gallbladder wall thickening

引用

World Journal of Gastroenterology 2020年第40期26卷 6163-6181页

作者： Pankaj Gupta Yashi Marodia Akash Bansal Naveen Kalra praveen Kumar-M Vishal Sharma Usha Dutta Manavjit Singh Sandhu Department of Radiodiagnosis and Imaging Postgraduate Institute of Medical Education and ResearchChandigarh 160012India Department of Pharmacology Postgraduate Institute of Medical Education and ResearchChandigarh 160012India Department of Gastroenterology Postgraduate Institute of Medical Education and ResearchChandigarh 160012India

Gallbladder(GB) wall thickening is a frequent finding caused by a spectrum of conditions. It is observed in many extracholecystic as well as intrinsic GB conditions. GB wall thickening can either be diffuse or focal. Diffuse wall thickening is a secondary occurrence in both extrinsic and intrinsic pathologies of GB, whereas, focal wall thickening is mostly associated with intrinsic GB pathologies. In the absence of specific clinical features, accurate etiological diagnosis can be challenging. The survival rate in GB carcinoma(GBC) can be improved if it is diagnosed at an early stage, especially when the tumor is confined to the wall. The pattern of wall thickening in GBC is often confused with benign diseases, especially chronic cholecystitis, xanthogranulomatous cholecystitis, and adenomyomatosis. Early recognition and differentiation of these conditions can improve the prognosis. In this minireview, the authors describe the patterns of abnormalities on various imaging modalities(conventional as well as advanced) for the diagnosis of GB wall thickening. This paper also illustrates an algorithmic approach for the etiological diagnosis of GB wall thickening and suggests a formatted reporting for GB wall abnormalities.

关键词： Gallbladder diseases Cholecystitis Rokitansky-Aschoff sinuses of the gallbladder Xanthogranulomatous cholecystitis Neoplasms Acute cholecystitis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：