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Teenage pregnancy and the sociodemographic attributes as a major contributor: Findings from an urban referral center in Nepal

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World Journal of Obstetrics and Gynecology 2021年第2期10卷 16-25页

作者： Puja Thapa Pukar Thapa Dhan Bahadur Shrestha pravash budhathoki Binod Karki Bimita Mahat Department of Anesthesiology Nepalese Army Institute of Health Sciences(NAIHS)Shree Birendra HospitalChhauniKathmandu 44600Nepal Hepatology Unit(Internal Medicine) National Academy of Medical Sciences(NAMS)Bir HospitalKathmandu 44600Nepal Department of Internal Medicine Mount Sinai HospitalChicagoIL 60608United States Department of Internal Medicine Bronxcare Health SystemBronxNY 10457United States Gastroenterology Unit Internal MedicineNational Academy of Medical Sciences(NAMS)Bir HospitalKathmandu 44600Nepal Department of Obstetrics and Gynecology Kathmandu Medical CollegeSinamangalKathmandu 44600Nepal

BACKGROUND Teenage pregnancy is a challenging issue ***,despite the increased health risk and socioeconomic impact of teenage pregnancy,the numbers remain high in *** To determine the prevalence and sociodemographic factors associated with teenage pregnancy in *** A hospital-based cross-sectional study was conducted in the Paropakar Maternity and Women’s Hospital from April to August 2017.A total of 1359 mothers were assessed and interviewed regarding their reproductive history and sociodemographic *** approval from the Nepal Health Research Council,permission from the concerned hospital,and consent from study subjects were *** Of the 5526 deliveries,679(12.3%)were teenage pregnancy *** majority(85.1%)of mothers(out of 1359)were married at<20 years of age,with a mean age of marriage of 17.57 years(±1.994,range:12-25 years).Marriage age was a significant determinant of teenage pregnancy(odds ratio[OR]2.423[2.262-2.596];P<0.001).Likewise,a love marriage(OR:2.018[1.585-2.570];P<0.001)and first teenage pregnancy(OR:3.622[3.265-4.017];P<0.001)were significant determinants for subsequent teen *** of family planning methods(OR:0.474;0.288-0.779;P=0.003)and use of any methods of family planning utilization(OR:0.345;0.248-0.479;P=0.000)significantly lowered the chance of teenage *** Teenage pregnancy occupies a substantial proportion of total deliveries in the Nepalese maternity *** addition,early pregnancy was significantly associated with age and type of marriage,education level,knowledge,and practice of contraceptive methods.

关键词： Contraception Nepal Reproductive health Teenage pregnancy Marriage Education

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New-onset diabetes in COVID-19 and clinical outcomes: A systematic review and meta-analysis

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World Journal of Virology 2021年第5期10卷 275-287页

作者： Dhan Bahadur Shrestha pravash budhathoki Sumit Raut Sugat Adhikari Prinska Ghimire Sabin Thapaliya Ali A Rabaan Bibodh Jung Karki Department of Internal Medicine Mount Sinai HospitalChicagoIL 60608United States Department of Internal Medicine BronxCare Health SystemBronxNY 10457United States Department of Emergency Medicine Kathmandu Medical CollegeKathmandu 44600Nepal Department of Internal Medicine Nishtar Medical UniversityMultan 59330Pakistan Department of Internal Medicine Tribhuvan UniversityKathmandu 44600Nepal Department of Internal Medicine Tribhuvan University Teaching HospitalKathmandu 44600Nepal Molecular Diagnostic Laboratory Johns Hopkins Aramco HealthcareDhahran 34465Saudi Arabia Department of Public Health&Nutrition The University of HaripurHaripur 22620Pakistan Division of Infectious Diseases University of LouisvilleLouisvilleKY 40292United States

BACKGROUND Diabetes mellitus(DM)is associated with adverse clinical outcomes and high mortality in patients with coronavirus disease 2019(COVID-19).The relationship between diabetes and COVID-19 is known to be *** To analyze the rate of new-onset diabetes in COVID-19 patients and compare the clinical outcomes of new-onset diabetes,pre-existing diabetes,hyperglycemic,and non-diabetes among COVID-19 *** We used the Meta-analysis of Observational Studies in Epidemiology statement for the present *** databases were searched for all peerreviewed articles published until November 6,*** were screened using Covidence and data *** analysis was done using comprehensive *** the 128 studies detected after thorough database searching,seven were included in the quantitative *** proportion was reported with 95%confidence interval(CI)and heterogeneity was assessed using *** Analysis showed that 19.70%(CI:10.93-32.91)of COVID-19 patients had associated DM,and 25.23%(CI:19.07-32.58)had associated *** overall mortality rate was 15.36%(CI:12.57-18.68)of all COVID-19 cases,irrespective of their DM *** mortality rate was 9.26%among non-diabetic patients,10.59%among patients with COVID-19 associated hyperglycemia,16.03%among known DM patients,and 24.96%among COVID-19 associated DM *** overall occurrence of adverse events was 20.52%(CI:14.21-28.70)among COVID-19 patients in the included studies,15.29%among non-diabetic patients,20.41%among patients with COVID-19 associated hyperglycemia,20.69%among known DM patients,and 45.85%among new-onset *** showed an increasing rate of mortality among new hyperglycemic patients,known diabetics,and new-onset DM patients in comparison to those without *** A significantly higher rate of new onset DM and hyperglycemia was *** mortality rates and adverse events were seen in patients with

关键词： Acute respiratory distress syndrome COVID-19 Diabetes mellitus Hyperglycemia Mortality

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