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Aetiology of extracranial carotid free-floating thrombus in a prospective multicentre cohort

Stroke & Vascular Neurology 2023年第3期8卷 194-196,I0005页

作者： Dar Dowlatshahi Cheemun Lum Bijoy K Menon Aditya Bharatha prasham dave Paulo Puac-Polanco Dylan Blacquiere Grant Stotts Michel Shamy Franco Momoli Rebecca Thornhill Ronda Lun Carlos Torres Department of Medicine University of OttawaOttawaOntarioCanada Clinical Epidemiology Ottawa Hospital Research InstituteOttawaOntarioCanada School of Epidemiology and Public Health University of OttawaOttawaOntarioCanada Department of Radiology University of OttawaOttawaOntarioCanada Departments of Clinical Neurosciences Radiology and Community Health SciencesUniversity of CalgaryCalgaryAlbertaCanada Department of Medical Imaging University of TorontoTorontoOntarioCanada Medicine Queen's UniversityKingstonOntarioCanada

Background Carotid free-floating thrombi(FFT)in patients with acute transient ischaemic attack(TIA)/stroke have a high risk of early recurrent *** depends on aetiology,which can include local plaque rupture,dissection,coagulopathy,malignancy and *** objectives were to classify the underlying aetiology of FFT and to estimate the proportion of patients with underlying stenosis requiring *** We prospectively enrolled consecutive patients presenting to three comprehensive stroke centres with acute TIA/stroke and ipsilateral internal carotid artery *** aetiology of FFT was classified as:carotid atherosclerotic disease,carotid dissection,cardioembolism,both carotid atherosclerosis and cardioembolism,or embolic stroke of uncertain source(ESUS).Patients with carotid atherosclerosis were further subclassified as having≥50%or<50%*** We enrolled 83 patients with confirmed *** assessments revealed 66/83(79.5%)had carotid atherosclerotic plaque,4/83(4.8%)had a carotid dissection,10/83(12%)had both atrial fibrillation and carotid atherosclerotic plaque and 3/83(3.6%)were classified as *** the 76 patients with atherosclerotic plaque(including those with atrial fibrillation),40(52.6%)had≥50%ipsilateral *** The majority of symptomatic carotid artery FFT are likely caused by local plaque rupture,more than half of which are associated with moderate to severe carotid stenosis requiring ***,a significant number of FFTs are caused by non-atherosclerotic mechanisms warranting additional investigations.

关键词： carotid prospective floating

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