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Irrational drug use-a pilot prescription study from Calicut,Kerala

海南医学院学报 2009年第12期15卷 1512-1515页

作者： Dilip C Saraswathi R Krishnan PN Vinod thomas Sanal dev prasanth nv subashpillai Al Shifa College Of Pharmacy

Objective:To describe the prescribing behavior of the physician in Kerala,and to describe types and number of medicine prescribed by doctors so as to rationalize the prescription writing habits of ***: A six month study was done to define the pattern of drug use in Medical college hospital,Calicut. The data and the other important aspects of study were collected by personal interview,questionnaires meant for doctors and prescription monitoring Performa for the patients issued by WHO. The findings of survey were critically ***: The results indicated that majority of doctors prescribed on the basis of patient's history,patient's feed back report,drug availability,brand cost,quality of drug and ADRs. All the interviewed doctors looked upon the side effects. It was found that individual drugs were prescribed more than fixed dose combinations (85.6%). Out of these 71.5% were prescribed as branded and 28.5% as generic. The demographic data,like name,age,sex,disease diagnosis were available on all the patient health care cards and these constituted an essential part of the prescription particularly age and sex being an important in deciding the dose preference for patients. Socio economically most patients were found to be in the grade ⅡI (Population below poverty line). During the study of drug related parameters,doses were mentioned only in 80% of the prescription. But duration of the drug therapy was found to be only 30%.These indicated the irrational use of prescription. Branded drugs prescribed were found to be 71.5%,which showed a trend towards a good prescription habit. The results indicated the rational use of ***: The survey reveales that most of the doctors in Medical college hospital,Calicut are maintaining rational use of drugs and their prescription writing habits was found to be good.

关键词：医生医师医学临床

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A pilot study on prevalence and cure rate of tuberculosis in selected areas of Malabar 2006-07.

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Asian Pacific Journal of Tropical Medicine 2009年第2期2卷 64-67页

作者： Dilip C Saraswathi R Christapher PV prasanth nv Sanal Dev Al Shifa College o Pharmacy KizhatturPerinthalmannaKerala.Pin-679325

Objective:To study the prevalence and cure rate of tuberculosis(TB) and the people affected by TB in selected areas,considering different factors like age,sex,percentage of people affected,dosage forms,role of hospitals, and patient ***:A detailed survey was carried out in and around Perinthalmanna and Wayanad(Urban and Rural) to understand the burden and overall trend of TB in our locality and how effective our TB control *** than 250 treatment cards were collected from the Government hospitals and TB ***:In the study,at Perinthalmanna and Wayanad,out of 250 TB patients it was found that males is more susceptible than females,rural area accounting for the greater proportion of TB patients. Greater proportion were affected with pulmonary than extra pulmonary *** incidence of tuberculosis in different age groups varied according to the *** proportion in both rural and urban areas were belonging to categoryⅡfollowed by categoryⅢ.Conclusion:The nature and magnitude of TB is more in rural area than urban area mainly because of the lack of awareness of the severity of disease and improper follow up of preventive *** study suggests that the combined and committed efforts of government,non government organizations,medical and paramedical professional and society is required at large,to reach all patients and ensure that they receive high quality care.

关键词： Directly observed treat short course(DOTS) Multi drug resistant tuberculosis(MDR -TB) Revised national TB control programme(RNTCP)

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Anti-inflammatory activity of the leaf extacts of Gendarussa vulgaris Nees

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Asian Pacific Journal of Tropical Biomedicine 2011年第2期1卷 147-149页

作者： TK Mohamed Saleem AK Azeem C Dilip C Sankar nv prasanth R Duraisami Al Shifa College of Pharmacy Poonthavanam P.OKizhatturPerinthalmannaMalappuram dist Kerala Nandha College of Pharmacy

Objective:To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris(***) ***:*** Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers,sores,inflammation, dyspepsia,healing of wounds,*** present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro and in vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation(HRBC) method and in vivo method was estimated on the carrageenan induced paw ***:Both the methods showed significant anti-inflammatory property of the different extracts tested. Conclusions:The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium.

关键词： Gendarussa vulgaris Anti-inflamation HRBC Carrageenan

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