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Mosaicing of multiplanar regions through autonomous navigation of off-the-shelf quadcopter

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IET Cyber-Systems and Robotics 2019年第3期1卷 81-92页

作者： Meghshyam G.Prasad Sona praneeth Akula Anirudh Vemula Sharat Chandran Department of Computer Science and Engineering IIT BombayIndia Robotics Institute Carnegie Mellon UniversityPA 15213USA

The real world is made up of multiplanar and curved *** such surfaces with an orthographic view using a handheld camera is tiring if the scene encompasses a view larger than the camera field of *** the scene is geographically beyond the reach of humans,or access to the scene is denied,it is not possible to take such a frontal view of the scene from handheld *** advent of inexpensive flying vehicles such as quadcopters enables the orthographic imaging of large surfaces for later analysis either for leisure or serious scientific ***,manual navigation of the quadcopter around such surfaces is tedious and results are not *** this paper,the authors present a method for autonomous navigation of a quadcopter for imaging multiplanar *** proposed method builds on the existing parallel tracking and mapping based approach to create an approximate sparse three-dimensional map of the input ***,the authors determine precise locations for obtaining videos for each bounded plane,and then autonomously manoeuver the quadcopter at these *** results in an end-to-end application for visualising scenes with an off-the-shelf quadcopter.

关键词： Mosaic autonomous shelf

Dispersion Modeling of Particulate Matter in Different Size Ranges Releasing from a Biosolids Applied Agricultural Field Using Computational Fluid Dynamics

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Advances in Chemical Engineering and Science 2021年第2期11卷 180-202页

作者： praneeth Nimmatoori Ashok Kumar Department of Civil and Environmental Engineering The University of Toledo Toledo OH USA

This paper proposes a methodology using computational fluid dynamics (CFD)-FLUENT to simulate the dispersion of particulate matter releasing from a biosolid applied agricultural field and predict the particulate concentrations for different ranges of particle sizes. The discrete phase model (Lagrangian-Eulerian approach) was used in combination with each of the four turbulence models: Standard kε (kε), Realizable kε (Rkε),

Real-time computerized video enhancement for minimally invasive fetoscopic surgery

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Laparoscopic, Endoscopic and Robotic Surgery 2018年第2期1卷 27-32页

作者： praneeth Sadda John Onofrey Metehan Imamoglu Xenophon Papademetris Bilal Qarni Mert Ozan Bahtiyar Department of Radiology and Biomedical Imaging Yale University School of Medicine333 Cedar StreetNew HavenCT 06510USA Department of Obstetrics Gynecology and Reproductive SciencesYale University School of Medicine333 Cedar StreetNew HavenCT 06510USA Department of Biomedical Engineering Yale University School of Medicine333 Cedar StreetNew HavenCT 06510USA Department of Obstetrics and Gynecology Yale University School of Medicine333 Cedar StreetNew HavenCT 06510USA Yale Fetal Care Center Yale-New Haven Hospital1 Long Wharf DriveNew HavenCT 06510USA University of Western Ontario 1151 Richmond StreetLondonON N6A 3K7Canada

Background:The only definitive treatment for twin-to-twin transfusion syndrome is minimally invasive fetoscopic surgery for the selective coagulation of placental blood *** surgery is a technically challenging operation,mainly due to the poor visibility conditions in the uterine *** present the design of an algorithm for the computerized enhancement of fetoscopic video and show that the enhanced video increases the ability of human users to identify blood vessels within fetoscopic video rapidly and ***:A computer algorithm for the enhancement of fetoscopic video frames was ***,optical fiber artifacts were removed via a modification of unsharp ***,image contrast was increased via Contrast Limited Adaptive Histogram Equalization(CLAHE).Third,the effect of contrast enhancements on stationary features was removed by normalizing to a windowed mean of the video ***,color information was reincorporated by combining the mean-normalized result with the unnormalized contrast enhanced image using the soft light blending *** trainees(n?16)were recruited into a study to validate the *** were shown enhanced or unenhanced fetoscopic video frames on a screen and were asked to identify whether a randomly placed marker fell on a blood vessel or on *** accuracy of their responses was ***:On the subset of images where subjects had the lowest mean accuracy in identifying the placement of the marker,subjects performed better when viewing video frames enhanced by the computer(accuracy 74.27%;SE 0.97)than when viewing unenhanced video frames(accuracy 63.78%;SE 2.79).This result was statistically significant(p<0.01).Conclusion:Real-time computerized enhancement of fetoscopic video has the potential to ease the readability of video in poor lighting conditions,thus providing a benefit to the surgeon intraoperatively.

关键词： Computer enhancement Fetoscopic surgery Fetoscopy Twin-to-twin transfusion syndrome Placental vasculature

Quantification of vascular morphology in optical coherence tomography angiography in primary open angle glaucoma

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Advances in Ophthalmology Practice and Research 2023年第3期3卷 119-125页

作者： praneeth Kalva Rubeel Akram Priya Mekala Monica Patel Sruthi Suresh Karanjit S.Kooner Department of Ophthalmology University of Texas at Southwestern Medical CenterDallasTXUSA Department of Ophthalmology Veteran Affairs North Texas Health Care Medical CenterDallasTXUSA

open-angle glaucoma(POAG)using optical coherence tomography angiography(OCTA)***:This is a retrospective and cross-sectional study which include healthy individuals and individuals with POAG that underwent OCTA imaging at an academic center's glaucoma *** analyzed OCTA scans of the macula and optic nerve head(ONH)of one eye from each subject to quantitatively measure vessel density(VD),vessel length density(VLD),and branchpoint density(BPD).We compared these 3 parameters between the healthy and POAG groups and used logistic regression classification models to determine their diagnostic value in differentiating healthy and glaucomatous ***:We included 49 healthy subjects and 49 subjects with *** age-adjusted analysis,the parameters of VD,VLD,and BPD were significantly reduced in eyes with POAG(P<0.001)in all scan layers and most significantly around the *** parameter with the best performances were radial peripapillary capillary(RPC)VD[AUC(areas under the curve):0.939(0.891,0.987)]which had statistically higher performances(P<0.05)than parameters in the superficial or deep *** 3 parameters in the RPC layer had statistically similar ***:We found that VD,VLD,and BPD were reduced in glaucomatous *** morphologic parameters of VLD and BPD had similar performances to the traditional parameter of VD in RPC *** results suggest that vascular morphology parameters may provide additional value in the diagnosis and evaluation of glaucoma.

关键词： Optical coherence tomography angiography Glaucoma Vessel density

Microarchitectural mimicking of stroma-induced vasculature compression in pancreatic tumors using a 3D engineered model

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Bioactive Materials 2023年第4期22卷 18-33页

作者： Marcel Alexander Heinrich Irene Uboldi praneeth Reddy Kuninty Marc J.K.Ankone Joop van Baarlen Yu Shrike Zhang Kartik Jain Jai Prakash Department of Advanced Organ Bioengineering and Therapeutics Engineered Therapeutics SectionTechnical Medical CentreUniversity of Twente7500AEEnschedethe Netherlands Laboratorium Pathologie Oost-Nederland(LabPON) 7550 AMHengelothe Netherlands Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical School65 Landsdowne StCambridgeMA02139USA Department of Thermal and Fluid Engineering Biofluid Dynamics SectionUniversity of Twente7500 AE Enschedethe Netherlands

Fibrotic tumors,such as pancreatic ductal adenocarcinoma(PDAC),are characterized for high desmoplastic reaction,which results in high intra-tumoral solid stress leading to the compression of blood *** microarchitectural alterations cause loss of blood flow and poor intra-tumoral delivery of ***,there is a lack of relevant in vitro models capable of replicating these mechanical characteristics and to test anti-desmoplastic ***,a multi-layered vascularized 3D PDAC model consisting of primary human pancreatic stellate cells(PSCs)embedded in collagen/fibrinogen(Col/Fib),mimicking tumor tissue within adjunct healthy tissue,is presented to study the fibrosis-induced compression of vasculature in *** is demonstrated how the mechanical and biological stimulation induce PSC activation,extracellular matrix production and eventually vessel *** clinical relevance is confirmed by correlating with patient transcriptomic ***,the effects of gradual vessel compression on the fluid dynamics occurring within the channel is evaluated in ***,it is demonstrated how cancer-associated fibroblast(CAF)-modulatory therapeutics can inhibit the cell-mediated compression of blood vessels in PDAC in vitro,in silico and in *** is envisioned that this 3D model is used to improve the understanding of mechanical characteristics in tumors and for evaluating novel anti-desmoplastic therapeutics.

关键词： Pancreatic ductal adenocarcinoma Cancer-associated fibroblasts Collagen Fibrinogen Computational flow dynamics 3D in vitro model

Vitamin B12 deficiency in dialysis patients:risk factors,diagnosis,complications,and treatment:A comprehensive review

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World Journal of Nephrology 2024年第4期13卷 28-39页

作者： Ghada Araji praneeth R Keesari Varun Chowdhry Jonathan Valsechi-Diaz Sarah Afif Wassim Diab Suzanne El-Sayegh Department of Internal Medicine Northwell Health-Staten Island University HospitalStaten IslandNY 10305United States Department of Internal Medicine CUNY School of MedicineNew YorkNY 10031United States Department of Nephrology Northwell Health-Staten Island University HospitalStaten IslandNY 10305United States

Vitamin B12 deficiency is a significant concern among patients with end-stage renal disease undergoing ***,there hasn’t been extensive research conducted on this particular patient *** reported incidence rates vary widely,ranging from 20%to 90%,reflecting the complexity of its *** patients often face multiple nutritional deficiencies,including a lack of essential vitamins,due to factors such as dietary restrictions,impaired absorption,and nutrient loss during *** vitamin B12 deficiency in these patients is challenging,and addressing it is crucial to prevent complications and improve their overall quality of *** review paper delves into the available body of evidence on vitamin B12 deficiency in dialysis patients,examining the contributing risk factors,diagnostic challenges,potential complications,and available treatment *** provides a well-rounded perspective on the topic,making it a valuable resource for researchers,healthcare practitioners,and policymakers interested in addressing the nutritional needs of dialysis patients.

关键词： Vitamin B12 deficiency Dialysis Risk factors Diagnostic challenges Complications Treatment

Evaluation of in-vitro antibacterial activity and anti-inflammatory activity for different extracts of Rauvolfia tetraphylla *** bark

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Asian Pacific Journal of Tropical Biomedicine 2012年第10期2卷 818-821页

作者： B.Ganga Rao P.Umamaheswara Rao E.Sambasiva Rao T.Mallikarjuna Rao V.S.praneeth.D A.U College of Pharmaceutical Sciences Andhra UniversityVisakhapatnamA.P

Objective:To assess the in-vitro antihacterial activity and anti-inflammatory activity of orally administered different extracts(Hydro-alcoholic,methanolic,ethyl acetate and hexane)of Rauvolfia tetraphylla(***)root bark in Carrageetiaii induced acute inflammation in ***:In-vitro antibacterial activity was evaluated for extracts against four Gram positive and four Gram negative bacteria by using cylinder plate ***-alcoholic extract(70%v/v ethanol)at 200,400 and 800 mg/kg doses and methanolic,ethyl acetate and hexane extracts at doses 100,200 and 400 mg/kg were tested for anti-inflammatory activity in Carrageenan induced rat paw oedema model and paw thickness was measured every one hour up to 6 ***:All extracts of *** root bark showed good zone of inhibition against tested bacterial *** Carrageenan induced inflammation model,hydro-alcoholic and methanolic extract of *** root bark at three different doses produced significant(P<0.00l)reduction when compared to vehicle treated control group and hexane,ethyl acetate ***:In the present study extracts of *** root bark shows good in-vitro antibacterial activity and in-vivo anti-inflammatory activity in rats.

关键词： Rauvolfia tetraphylla Root bark In-vitro antibacterial activity Inflammation Anti-inflammatory activity

Common Complication in an Uncommon Disease: Presence of Aortic Regurgitation in Patient with Quadricuspid Aortic Valve

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International Journal of Clinical Medicine 2016年第3期7卷 231-235页

作者： Adikesava Naidu Otikunta Y. V. Subba Reddy praneeth Polamuri Ravi Srinivas Department of Cardiology Osmania General Hospital Hyderabad India

Background: Congenital heart defect exists from birth but is usually detected in a later stage of life, as in case of quadricuspid aortic valve. A great majority of quadricuspid aortic valves do not have a normal function and often necessitate surgical treatment. Aim: To report a case with quadricuspid aortic valve accompanied with complications. Case Presentation: We present a case of a male detected with quadricuspid aortic valve of four equal sized cusps accompanied by abnormalities, yet managed successfully under conservative treatment. Conclusion: Patients with a quadricuspid aortic valve require careful clinical evaluation and close follow up.

关键词： Aortic Valve Congenital Heart Defect Echocardiography

Accelerated Atherosclerosis in a Young Female with Familial Hypercholesterolemia

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International Journal of Clinical Medicine 2014年第10期5卷 541-545页

作者： Adikesava Naidu Otikunta praneeth Polamuri Subba Reddy Y V Ravi Srinivas Ashok Thakkar Arohi Sarang Department of Cardiology Osmania General Hospital & Osmania Medical College Hyderabad India Department of Clinical Trials Sahajanand Medical Technologies Pvt. Ltd. Surat India

Familial hypercholesterolemia is an autosomal dominant genetic disease due to mutation in low-density lipoprotein-cholesterol receptor gene. It is characterized by elevated plasma low-density lipoprotein-cholesterol and the consequence of which leads to premature cardiovascular disease. The mainstay in the management of familial hypercholesterolemia patient is the treatment with high potency statin. However, current research shows influence of the type of low-density lipoprotein-cholesterol receptor mutations on severity of the cardiovascular disease, lipid profile, and response to statin treatment. We are here presenting a case of young Indian female patient who was diagnosed with familial hypercholesterolemia and treated with percutaneous transluminal coronary angioplasty in view of double vessel disease in the third decade of her life. She was prescribed with statin therapy for elevated low-density lipoprotein cholesterol. After 3 years, she presented once again with a triple vessel disease along with patent stented segments and abnormal lipid profile.

关键词： Familial Hypercholesterolemia Premature Coronary Artery Disease Statin