检索结果-南通市图书馆

A dahlia flower extract has antidiabetic properties by improving insulin function in the brain

Life Metabolism 2023年第4期2卷 39-50页

作者： Dominik Pretz Philip M.Heyward Jeremy Krebs Joel Gruchot Charles Barter Pat Silcock Nerida Downes Mohammed Zubair Rizwan Alisa Boucsein Julia Bender Elaine J.Burgess Geke Aline Boer pramuk keerthisinghe Nigel B.Perry Alexander Tups Centre for Neuroendocrinology School of Biomedical SciencesUniversity of OtagoDunedin 9054New Zealand Department of Physiology School of Biomedical SciencesUniversity of OtagoDunedin 9054New Zealand Maurice Wilkins Centre for Molecular Biodiscovery University of AucklandAuckland 1010New Zealand Department of Medicine University of OtagoWellingtonWellington South 6242New Zealand Centre for Endocrine Diabetes and Obesity Research Wellington Regional HospitalNewtownWellington 6021New Zealand Product Development Research Centre University of OtagoDunedin 9054New Zealand Department of Chemistry The New Zealand Institute for Plant and Food ResearchUniversity of OtagoDunedin 9054New Zealand

Butein,a rare chalcone found in the toxic plant Toxicodendron vernicifluum,has been shown to regulate glucose homeostasis via inhibition of the nuclear factor kappa-B kinase subunit beta(IKKβ)/nuclear factor kappa B(NF-κB)pathway in the ***,we investigated whether the nonpoisonous plant Dahlia pinnata could be a source of butein as a potential treatment for type 2 diabetes(T2D).In mice fed a high-fat diet(HFD)to induce glucose intolerance,an oral *** petal extract improved glucose tolerance at doses of 3.3 mg/kg body weight and 10 mg/kg body ***,this effect was not mediated by butein alone but by butein combined with the closely related flavonoids,sulfuretin and/or ***,the extract improved systemic insulin *** of phosphatidylinositol 3-kinase to block insulin signaling in the brain abrogated the glucoregulatory effect of the orally administered *** extract reinstated central insulin signaling and normalized astrogliosis in the hypothalamus of HFD-fed *** NF-κB reporter zebrafish to determine IKKβ/NF-κB activity,a potent anti-inflammatory action of the extract was found.A randomized controlled crossover clinical trial on participants with predia-betes or T2D confirmed the safety and efficacy of the extract in *** conclusion,we identified an extract from the flower petals of *** as a novel treatment option for T2D,potentially targeting the central regulation of glucose homeostasis as a root cause of the disease.

关键词： inflammation hypothalamus signal transduction neuroendocrine arcuate nucleus

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Case Depth Measurement of Induction Hardening Using Image Processing

引用

材料热处理学报 2004年第5期25卷 564-566页

作者： Kitti Pongsathaporn pramuk Jenkittiyon Siriporn Daopiset Somnuk Watanasriyakul Production Engineering Department Engineering Faculty King Mongkut's Institute of Technology North Bangkok ThailandProduction Engineering Department Engineering Faculty King Mongkut's Institute of Technology North Bangkok ThailandProduction Engineering Department Engineering Faculty King Mongkut's Institute of Technology North Bangkok ThailandProduction Engineering Department Engineering Faculty King Mongkut's Institute of Technology North Bangkok Thailand

Case depth measurement of the induction hardened steel parts is necessary for quality control. Vickers microhardness test is the most industrially accepted method to identify the case depth. But this method is a time consuming one and it requires expensive equipment. The aim of this study is to develop a different method to determine the case depth using image processing. The surface hardened steel samples were cross cut, ground and etched with Nital. The etched macrosectioned specimens were scanned by a scanner. The scanned images were evaluated by the developed software. The principle of the software is to identify the gray level difference. The effective case depths of the surface hardened specimens obtained by Vickers microhardness test and the developed method were compared. It was found that the deviation of the developed method was ±0.12 mm at the case depth range of 0.6 - 2.0 mm and mm at the case depth range of 2.1 - 4.3 mm. The measuring time was only 20% of Vickers microhardness test. The deviation range is much lower than the tolerance case depth specification for induction hardening in general.

关键词：图像处理表面硬化深度感应淬火质量控制

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

温度和光照对草花生长的影响

引用

中国花卉园艺 2006年第18期 22-25页

作者： Lee pramuk Erik Runkle 林子

石油价格的不断上涨,给花卉生产者在冬季的生产增加了相当大的成本.为了降低燃油成本而获得最大的利润,他们只能尽量降低温室内的温度,但是,温度降低后对于花卉的生长、发育的影响却少有研究.前几年,美国密歇根州立大学的有关人员开始... 详细信息

石油价格的不断上涨,给花卉生产者在冬季的生产增加了相当大的成本.为了降低燃油成本而获得最大的利润,他们只能尽量降低温室内的温度,但是,温度降低后对于花卉的生长、发育的影响却少有研究.前几年,美国密歇根州立大学的有关人员开始研究温度和光照对广泛应用的四种花坛花卉的影响.

关键词：温度降低生长光照美国密歇根州立大学草花花坛花卉燃油成本石油价格

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：