检索结果-南通市图书馆

Genes & Diseases 2017年第4期4卷 196-203页

作者： Manju tiwari Department of Biochemistry and Genetics Barkatullah UniversityBhopalMadhya PradeshIndia

Glucose 6 phosphate dehydrogenase(G6PD)is a k.y and rate limiting enzyme in the pentose phosphate pathway(PPP).The physiological significance of enzyme is providing reduced energy to specific cells lik. erythrocyte by maintaining co-enzyme nicotinamide adenine dinucleotide phosphate(NADPH).There are preponderance research findings that demonstrate the enzyme(G6PD)role in the energy balance,and it is associated with bloodrelated diseases and disorders,primarily the anemia resulted from G6PD *** Xlink.d genetic deficiency of G6PD and associated non-immune hemolytic anemia have been studied widely across the *** advancement in biology,more precisely neuroscience has revealed that G6PD is centrally involved in many neurological and neurodegenerative *** neuroprotective role of the enzyme(G6PD)has also been established,as well as the potential of G6PD in oxidative damage and the Reactive Oxygen Species(ROS)produced in cerebral *** G6PD deficiency remains a global health issue,however,a paradigm shift in research focusing the potential of the enzyme in neurological and neurodegenerative disorders will surely open a new avenue in diagnostics and enzyme ***,in this study,more emphasis was made on exploring the role of G6PD in neurological and inflammatory disorders as well as non-immune hemolytic anemia,thus providing diagnostic and therapeutic opportunities.

关键词： Glucose 6 phosphate dehydrogenase Hemolytic anemia Metabolic disorders Neurodegenerative disorders

Epidemiology of pediatric burns and future prevention strategies—a study of 475 patients from a high-volume burn center in North India

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Burns & Trauma 2017年第1期5卷 50-57页

作者： Amol Dhopte V.k.tiwari Pank.j Patel Rahul Bamal Department of Burns Plastic&Maxillofacial SurgeryVMMC&Safdarjung HospitalNew DelhiIndia Present Address:Department of Burns&Plastic Surgery PGIMER&RML HospitalNew DelhiIndia

Back.round: Pediatric burns have a long-term social impact. This is more apparent in a developing country such as India, where their incidence and morbidity are high. The aim of this study was to provide recent prospective epidemiological data on pediatric burns in India and to suggest future preventive strategies. Methods: Children up to 18 years old admitted to the Department of Burns, Plastic&Maxillofacial Surgery, VMMC&Safdarjung Hospital, New Delhi, between January and December 2014 were included in the study. Data regarding age, sex, etiology, total body surface area (TBSA), circumstances of injury, and clinical assessment were collected. The Mann-Whitney test or k.usk.l-Wallis test or ANOVA was used to compare involved TBSA among various cohort groups accordingly. Univariate and multivariate linear regression analyses were used to determine the predictors of TBSA. Results: There were a total of 475 patients involved in the study, including seven suicidal burns, all of whom were females with a mean age greater than the cohort average. Age, type of burns, mode of injury, presence or absence of inhalation injury, gender, and time of year (quarter) for admission were found to independently affect the TBSA involved. Electrical burns also formed an important number of presenting burn patients, mainly involving teenagers. Several societal issues have come forth, e.g., child marriage, child labor, and lik.ly psychological problems among female children as suggested by a high incidence of suicidal burns. Conclusions: This study also highlights several issues such as overcrowding, lack.of awareness, dangerous cook.ng practices, and improper use of k.rosene oil. There is an emergent need to recognize the problems, formulate strategies, spread awareness, and ban or replace hazardous substances responsible for most burn accidents.

关键词： Epidemiology Pediatric burns India Suicidal burns Burn prevention

Visceral leishmaniasis: An immunological viewpoint on asymptomatic infections and post k.la azar dermal leishmaniasis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2018年第2期11卷 98-108页

作者： Neeraj tiwari Dhiraj k.shore Surabhi Bajpai Rak.sh k.Singh Department of Biochemistry Institute of ScienceBanaras Hindu University Department of Medicine Institute of Medical SciencesBanaras Hindu University Department of Bioscience and Biotechnology Banasthali University

Elimination of visceral leishmaniasis is a priority programme in Indian *** World Health Organization has set a new target to eliminate k.la-azar by the year 2020 as previous target elimination year(2015) has *** elimination programme has successfully curbed the rate of infection in endemic regions; however, there are still few challenges in its *** current drug control regime is extremely limited and comprises only two(amphotericin B and miltefosine) drugs, which are also susceptible for parasites ***, these drugs do not produce sterile cure, and cured patients may develop post k.la-azar dermal leishmaniasis even after a decade of cure leaving behind a potent source of parasitic reservoirs for further disease transmission.A significant proportion of endemic population remain seropositive but aymptomatic for many years without any clinical symptom that serve as latent parasitic *** lack.of tools to identify live parasites in asymptomatic infections and there association in disease transmission, parameters of sterile cure along with post k.la-azar dermal leishmaniasis progression remain a major threat in its *** this review, we discuss the potential of host immune inhibitory mechanisms to identify immune correlates of protective immunity to understand the mystery of asymptomatic infections, sterile cure and post k.la azar dermal leishmaniasis.

关键词： Visceral leishmaniasis Immune response Asymptomatic infection Sterile cure Post k.la-azar dermal leishmaniasis

Fermentation characteristics of resistant starch, arabinoxylan, andβ-glucan and their effects on the gut microbial ecology of pigs:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Animal Nutrition 2019年第3期5卷 217-226页

作者： Utsav P.tiwari Amit k.Singh Rajesh Jha Department of Human Nutrition Food and Animal Sciences College of Tropical Agriculture and Human ResourcesUniversity of Hawaii at Manoa

Dietary fibers(DF)contain an abundant amount of energy,although the mammalian genome does not encode most of the enzymes required to degrade ***,a mutual dependence is developed between the host and symbiotic microbes,which has the potential to extract the energy present in these *** fibers escape digestion in the foregut and are fermented in the hindgut,producing shortchain fatty acids(SCFA)that after the microbial ecology in the gastrointestinal tract(GIT)of *** of the carbohydrates are fermented in the proximal part,allowing protein fermentation in the distal part,resulting in colonic *** structures of resistant starch(RS),arabinoxylan(AX),and β-glucan(βG)are complex;hence,mak.s their way into the hindgut where these are fermented and provide energy substrates for the colonic epithelial *** microbes have different preferences of binding to different *** RS,AX and βG act as a unique substrate for the microbes and modify the relative composition of the gut microbial *** granule dimension and surface area of each substrate are different,which influences the penetration capacity of *** and xylan are 2 different hemicelluloses,but arabinose is substituted on the xylan back.one and occurs in the form of *** of xylan produces butyrate primarily in the small intestine,whereas arabinose produces butyrate in the large *** of RS and forms of βG also exert beneficial effects by producing different metabolites and modulating the intestinal ***,it is important to have information of different types of RS,AX and(3 G and their roles in microbial modulation to get the optimum benefits of fiber fermentation in the *** review provides relevant information on the similarities and differences that exist in the way RS,AX,and βG are fermented,and their positive and negative effects on SCFA production and gut microbial ecology of *** insights will help nutr

关键词： Butyrate Fermentation Gut ecology Microbiota Short-chain fatty acids Swine

Controlled Synthesis and Growth of Perfect Platinum Nanocubes Using a Pair of Low-Resistivity Fastened Silicon Wafers and Their Electrocatalytic Properties

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nano Research 2011年第6期4卷 541-549页

作者： Jitendra N. tiwari Rajanish N. tiwari k.nlin Lin Department of Materials Science and Engineering National Chiao Tung University 1001 Ta Hsueh Road Hsinchu Taiwan 30050China Center for Superfunctional Materials Department of Chemistry Pohang University of Science and Technology San 31 Hyojadong NamguPohang 790-784 South Korea National Nano Device Laboratories No. 26 Prosperity Road I Science-Based Industrial Park Hsinchu Taiwan 30078 China

Perfect platinum （Pt） nanocubes with high density have been synthesized by controlled reduction of hexachloroplatinic acid in the presence of H2SO4 and HCl, employing a pair of low-resistivity fastened silicon （FS） wafers at room temperature. The presence of the additive charges （induced by prior etching of the silicon surface with HF to remove any SiO2 layer） between the interfaces of the FS surface results in a high charge density and facilitates fast deposition of Pt nanoparticles via electroless plating. The charge density, stirring time, and homogeneity of the aqueous solution influenced the geometrical shapes of the Pt nanoparticles. The parameters were finely tuned in order to control the nucleation and growth rates and obtain perfect Pt nanocubes. The perfect Pt nanocubes were single crystalline with exposed {100} facets. Per equivalent Pt surface areas, the perfect Pt nanocubes showed enhanced catalytic activity relative to truncated Pt nanocubes or spherical Pt nanoparticles for the electrooxidation of liquid feed fuels such as methanol and ethanol. Moreover, there a strong correlation was observed between the optical, electrical, thermal, magnetic, and catalytic properties of the perfect Pt nanocubes which should lead to a variety of technological applications of these materials.

关键词： Fastened silicon wafers charge density Pt nanocubes catalytic activity liquid feed fuel cells

Analyzing geomorphological and topographical controls for the heterogeneous glacier mass balance in the Sik.im Himalayas

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mountain Science 2023年第7期20卷 1854-1864页

作者： GUHA Supratim tiwari Reet k.mal Geomatics Engineering Laboratory Department of Civil EngineeringIndian Institute of Technology RoparPunjab-140001India

Glacier response patterns at the catchment scale are highly heterogeneous and defined by a complex interplay of various dynamics and surface *** studies have explained heterogeneous responses in qualitative ways but quantitative assessment is lack.ng yet where an intrazone homogeneous climate assumption can be ***,in the current study,the reason for heterogeneous mass balance has been explained in quantitative methods using a multiple linear regression model in the Sik.im Himalayan *** first,the topographical parameters are selected from previously published studies,then the most significant topographical and geomorphological parameters are selected with back.ard stepwise subset selection ***,the contributions of selected parameters are calculated by least square *** results show that,the magnitude of mass balance lies between-0.003±0.24 to-1.029±0.24 m.w.e.a^(-1) between 2000 and 2020 in the Sik.im Himalaya ***,the study shows that,out of the terminus type of the glacier,glacier area,debris cover,ice-mixed debris,slope,aspect,mean elevation,and snout elevation of the glaciers,only the terminus type and mean elevation of the glacier are significantly altering the glacier mass balance in the Sik.im Himalayan ***,the mass loss is approximately 0.40 m.w.e.a^(-1) higher in the lak.-terminating glaciers compared to the land-terminating glaciers in the same elevation *** the other hand,a thousand meters mean elevation drop is associated with 0.179 m.w.e.a-1of mass loss despite the terminus type of the *** the current study,the model using the terminus type of the glaciers and the mean elevation of the glaciers explains 76% of fluctuation of mass balance in the Sik.im Himalayan region.

关键词： Glacier mass balance Glacier terminus Topographical parameter Sik.im Himalaya Multiple linear regression model

Solution of Electrohydrodynamic Flow Equation Using an Orthogonal Collocation Method Based on Mixed Interpolation

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Applied Mathematics and Physics 2018年第3期6卷 573-587页

作者： Shruti tiwari Ram k. Pandey Department of Mathematics and Statistics Dr. H.S. Gour Vishwavidyalaya Sagar India

In this Paper, we have proposed a new weighted residual method k.own as orthogonal collocation-based on mixed interpolation (OCMI). Mixed interpolation uses the classical polynomial approximation with two correction terms given in the form of sine and cosine function. By these correction terms, we can control the error in the solution. We have applied this approach to a non-linear boundary value problem (BVP) in ODE which governs the electrohydrodynamic flow in a cylindrical conduit. The solution profiles shown in the figures are in good agreement with the work.of Paullet (1999) and Ghasemi et al. (2014). Our solution is monotonic decreasing and satisfies , where, α governs the strength of non-linearity and for large values of α solutions are . The residual errors are given in Table 1 and Table 2 which are significantly small. Comparison of residual errors between our proposed method, Least square method and Homotopy analysis method is also given and shown via the Table 3 where as the profiles of the residual error are depicted in Figures 4-8. Table and graphs show that efficiency of the proposed method. The error bound and its L2-norm with relevant theorems for mixed interpolation are also given.

关键词： Electrohydrodynamic (EHD) Flow Weighted Residual Method Orthogonal Polynomial Mixed Interpolation

Non-Darcy Mixed Convection between Differentially Heated Vertical Walls Filled with a Porous Material: Application of New Modified Adomian Decomposition Method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Fluid Dynamics 2015年第4期5卷 380-390页

作者： A. k. tiwari Premlata Singh Department of Applied Mathematics Birla Institute of Technology Mesra Ranchi Extension Centre Patna India

This paper presents non-Darcy mixed convective flow of an incompressible and viscous fluid in a differentially heated vertical channel filled with a porous material in the presence of a temperature dependent source/sink. The analytical solution of fourth order non-linear ordinary differential equation for temperature field, which is formed by eliminating velocity field from system of governing equations in non-dimensional form, is obtained by using new modified Adomian decomposition method (NMADM) in terms of various parameters. In order to illustrate the interactive influences of governing parameters on the temperature and velocity fields, a numerical study of the analytical solution is performed with respect to three categories of transport processes i) when forced convection is dominated, ii) when forced and natural convection are equal and iii) when natural convection is dominated. Analysis of all categories has revealed that the temperature and velocity profiles are increasing function of modified Darcy number while decreasing function of Forchheimer number.

关键词： Non-Darcy Mixed Convection Porous Media Differentially Heated New Modified Adomian Decomposition Method (NMADM)

Evaluation of factors affecting the edge formability of two hot rolled multiphase steels

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2018年第2期25卷 199-215页

作者： Monideepa Muk.erjee Sumit tiwari Basudev Bhattacharya Research and Development TATA STEELJamshedpur 831001India PSG College of Technology Coimbatore 641004India

In this study, the effect of various factors on the hole expansion ratio and hence on the edge formability of two hot rolled multiphase steels, one with a ferrite–martensite microstructure and the other with a ferrite-bainite microstructure, was investigated through systematic microstructural and mechanical characterization. The study revealed that the microstructure of the steels, which determines their strain hardening capacity and fracture resistance, is the principal factor controlling edge formability. The influence of other factors such as tensile strength, ductility, anisotropy, and thick.ess, though present, are secondary. A critical evaluation of the available empirical models for hole expansion ratio prediction is also presented.

关键词： stretch flanging hole expansion ratio martensite bainite edge formability multiphase steels

A tip-coupled, two-cantilever, non-resonant microsystem for direct measurement of liquid viscosity

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microsystems & Nanoengineering 2023年第2期9卷 23-31页

作者： Sudhanshu tiwari Ajay Dangi Rudra Pratap Center for Nano Science and Engineering Indian Institute of ScienceBangaloreKarnataka 47906India Department of Biomedical Engineering Pennsylvania State UniversityUniversity ParkPA 16802USA Plak.ha University MohaliPunjabIndia Present address:Oxide MEMS Lab Purdue UniversityWest LafayetteUSA

We report a non-resonant piezoelectric microelectromechanical cantilever system for the measurement of liquid *** system consists of two PiezoMEMS cantilevers in-line,with their free ends facing each *** system is immersed in the fluid under test for viscosity *** of the cantilevers is actuated using the embedded piezoelectric thin film to oscillate at a pre-selected non-resonant *** second cantilever,the passive one,starts to oscillate due to the fluid-mediated energy *** relative response of the passive cantilever is used as the metric for the fluid's k.nematic *** fabricated cantilevers are tested as viscosity sensors by carrying out experiments in fluids with different *** viscometer can measure viscosity at a single frequency of choice,and hence some important considerations for frequency selection are discussed.A discussion on the energy coupling between the active and the passive cantilevers is *** novel PiezoMEMS viscometer architecture proposed in this work.will overcome several challenges faced by state-of-the-art resonance MEMS viscometers,by enabling faster and direct measurement,straightforward calibration,and the possibility of shear rate-dependent viscosity measurement.

关键词： cantilever viscosity resonant