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A Novel Workload-Aware and Optimized Write Cycles in NVrAM

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Computers, Materials & Continua 2022年第5期71卷 2667-2681页

作者： J.P.Shri Tharanyaa d.Sharmila r.Saravana kum.r department of ECE Bannari Amman Institute of TechnologyTamil NaduIndia department of CSE Jai Shriram Engineering CollegeTamil NaduIndia

With the emergence of the Internet of things(IoT),embedded systems have now changed its dimensionality and it is applied in various domains such as healthcare,home automation and mainly Industry *** Embedded IoT devices are mostly *** has been analyzed that usage of dynamic random-Access Memory(drAM)centered core memory is considered the most significant source of high energy utility in Embedded IoT *** achieving the low power consumption in these devices,Non-volatile memory(NVM)devices such as Parameter random Access Memory(pram)and Spin-Transfer Torque Magnetic randomAccess Memory(STT-rAM)are becoming popular among main memory alternatives in embedded IoT devices because of their features such as high thickness,byte addressability,high scalability and low power ***,Non-volatile random-Access Memory(NVrAM)is widely adopted to save the data in the embedded IoT ***,flash memories have a limited lifetime,so it is mandatory to adopt intelligent optimization in managing the NVrAM-based embedded devices using an intelligent controller while considering the endurance *** address this challenge,the paper proposes a powerful,lightweight machine learning-based workload-adaptive write schemes of the NVrAM,which can increase the lifetime and reduce the energy consumption of the *** proposed system consists of three phases like Workload Characterization,Intelligent Compression and Memory *** phases are used for distributing the write-cycles to NVrAM,following the energy-time consumption and number of data *** extensive experimentations are carried out using the IoMT(Internet of Medical things)benchmark in which the different endurance factors such as application delay,energy and write-time factors were evaluated and compared with the different existing algorithms.

关键词： Internet of things drAM pram STT-rAM machine learning internet of medical things endurance

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东西方酸相关性疾病的未来

中华消化杂志 2000年第5期20卷 333-334页

作者： Guido Tytgat Shiu-kum Lam James W.Freston Jose d.Sollano 戎兰陆玮荷兰阿姆斯丹大学医学中心胃肠和肝胆科上海医科大学华山医院消化科

许多著名胃肠病学专家于1998年11月消化病周聚集在菲律宾马尼拉一起讨论并报道了有关胃肠病学、肝病学和内镜方面的进展,这次会议引起了亚洲和西方消化界的极大兴趣.现将有关'胃食管反流性疾病'以及'兰索拉唑是安全和有效的'二部分内容... 详细信息

许多著名胃肠病学专家于1998年11月消化病周聚集在菲律宾马尼拉一起讨论并报道了有关胃肠病学、肝病学和内镜方面的进展,这次会议引起了亚洲和西方消化界的极大兴趣.现将有关'胃食管反流性疾病'以及'兰索拉唑是安全和有效的'二部分内容报告如下.

关键词：胃食管反流性疾病症状诊断治疗

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尖晶石:二维磁性材料家族新成员（英文）

Science Bulletin 2023年第11期 1087-1090页

作者：程瑞清 Hyun S.kum 何军 Key Laboratory of Artificial Micro-and Nano-structures of Ministry of Education and School of Physics and Technology Wuhan University Key Laboratory for Special Functional Materials of Ministry of Education Henan University department of Electrical and Electronic Engineering Yonsei University Wuhan Institute of Quantum Technology

Ultrathin two-dimensional(2d) materials have attracted considerable interest in recent years due to their fascinating properties and enormous potential in various fields. Among the vast family of2d materials, 2d magne...

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艾斯能对治疗合并有血管危险因素阿尔茨海默病患者的有效性和安全性研究(译文)

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中国神经免疫学和神经病学杂志 2001年第3期8卷 187-188页

作者： V.kum ar r.Anand J.Messina r.Hartm an J.Veach Florida Institute of Neurosciences and Clinical research 530S.Nokomis AvenueSuite14.Venice.FL34284Novartis Pharmaceuticals CorporationEast HanoverNJ.USA

在本研究中 ,我们使用中枢性胆碱酯酶抑制剂艾斯能 ,即瑞瓦斯的明 (酒石酸盐 rivastigmine,rSM) ,治疗合并和不合并血管危险因素 (VrF)的轻到中度阿尔茨海默病 (Ad)患者 ,评估其有效性和安全性。患者 (4 5～ 90岁 )被随机分为安慰剂组 (... 详细信息

在本研究中 ,我们使用中枢性胆碱酯酶抑制剂艾斯能 ,即瑞瓦斯的明 (酒石酸盐 rivastigmine,rSM) ,治疗合并和不合并血管危险因素 (VrF)的轻到中度阿尔茨海默病 (Ad)患者 ,评估其有效性和安全性。患者 (4 5～ 90岁 )被随机分为安慰剂组 (n=2 3 5)、低剂量 rSM组 (1～ 4 mg/d,n=2 3 3 )和高剂量 rSM组 (6～ 1 2 mg/d,n=2 3 1 ) ,并治疗 2 6周。有效性检测指标包括阿尔茨海默病评分量表 -认知功能亚量表 (AdAS-Cog)、以临床医生面访为基础的印象变化 (CIBIC-Plus)、进行性恶化量表 (PdS)、全面衰退量表 (GdS)以及简明智能状态量表(MMSE)。在进行有效性和安全性分析时 ,根据基线时改良的 Hachinski缺血量表评分 ,患者的 VrF被分为 2类 ,即 MHIS>0 :存在 VrF;MHIS=0 :不存在 VrF。在治疗 1 2周时 ,高剂量 rSM组与基线时相比 AdAS-Cog得分的平均变化 ,与安慰剂组相比差异有显著性 ,且这种差异在两类 MHIS中均存在。但是 ,每个时点时 ,高剂量rSM组与安慰剂组之间的差异 ,MHIS>0者更大。在每个改善水平 ,高剂量 rSM组所占的比例显著较高。在安全性评估时 ,各治疗组之间没有差异。rSM对各类患者均有效 ,有 VrF者 ,临床疗效更明显 (认知、日常生活能力、疾病严重程度 )

关键词：阿尔茨海默病胆碱酯酶抑制剂瑞瓦斯的明血管危险因素治疗

Solar Flare Activity and Variability of Electric Current Helicity

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Chinese Journal of Astronomy and Astrophysics 2002年第1期2卷 81-91页

作者： KimJikSu Hong－QiZhang 等 PyongyangAstronomicalObservatory AcademyofSciencesDPRofKorea NationalAstronomicalObservatories ChineseAcademyofSciencesBeijing100012

recent study using Huairou vector magnetograph data shows that durlug flare activity, the current helicity exhibits rapid and substantial variations and, in some cases, a recovering phase. We considered various representative the magnetic configurations. First, interacting twisted magnetic flux tubes are analyzed separately for positive, negative and mixed-sign helicity regions. The results show that the helicity during flares decreases in positive-sign, and increases in negative-sign regions. Then, flaring arcade also shows that the magnitude of the helicity decreases after flares. We also investigated current sheets formed by sheared magnetic field and showed that the current helicity (with either positive and negative signs) vanishes after reconnection. The emergence of twisted flux tubes which can trigger flares may be another source of flare-associated variability of current helicity. We demonstrate the relevance of current helicity to the description of flare activity by comparing its variation with that of shear angle in the active region Ar 6891.

关键词： Sun: flare -Sun: current helicity - Sun: magnetic shear

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World Journal of Gastroenterology 2008年第28期14卷 4535-4539页

作者： Guo-Shuang Feng Jun-Ling Ma Benjamin CY Wong Lian Zhang Wei-dong Liu Kai-Feng Pan Lin Shen Xiao-dong Zhang Jie Li Harry HX Xia Ji-You Li Shiu kum Lam Wei-Cheng You department of Cancer Epidemiology Peking University School ofOncology Beijing Cancer Hospital & Institute Beijing 100036 China department of Medicine University of Hong Kong Hong Kong China department of Medical Oncology Peking University School of Oncology Beijing Cancer Hospital & Institute Beijing 100036 China department of Pathology Peking University School of Oncology Beijing Cancer Hospital & Institute Beijing 100036 China Healthy Bureau of Linqu County Weifang 262600 Shandong Province China

AIM: To evaluate the long-term risk of gastroduodenal ulcer and cardiovascular events induced by celecoxib in a population-based, randomized, double-blind, placebo-controlled ***: From 2004 to 2006, a total of 1024 Chinese patients (aged 35 to 64 years) with severe chronic atrophic gastritis, intestinal metaplasia or dysplasia were randomly assigned to receive 200 mg of celecoxib twice daily or placebo in Linqu County (Shandong Province, China), a high-risk area of gastric cancer. All gastroduodenal ulcer and cardiovascular events occurred were recorded and the patients were followed up for 1.5 years after treatment. At the end of the trial, a systematic interview survey about other adverse events was conducted. rESULTS: Gastroduodenal ulcer was detected in 19 of 463 (3.72%) patients who received celecoxib and 17 of 473 (3.31%) patients who received placebo, respectively (odds ratio = 1.13, 95% CI = 0.58-2.19). Cardiovascular (CV) events occurred in 4 patients who received celecoxib and in 5 patients who received placebo, respectively. Compared with those who received placebo, patients who received celecoxib had no signif icant increase in occurrence of CV events (hazard ratio = 0.84, 95% CI = 0.23-3.15). Among the adverse events acquired by interview survey, only the frequency of bloating was signif icantly higher in patients treated with celecoxib than in those treated with placebo. CONCLUSION: Treatment of gastric cancer with celecoxib is not associated with increased risk of gastroduodenal ulcer and cardiovascular events.

关键词： Celecoxib Gastroduodenal ulcer Cardiovascular diseases Adverse effects Epidemiology randomized controlled trial

非胰岛素依赖型糖尿病伴特发性尿崩症一例报告

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中华内分泌代谢杂志 1991年第4期07卷 53-53页

作者：张如根项坤三黄琪仁上海市第六人民医院内分泌科上海市第六人民医院内分泌科 200233

患者男,70岁,退休工人。1989年6月起多饮、多尿伴体重下降及全身乏力。外院查空腹血糖12.4～13.3mmol/L,尿糖(++++)。诊断为糖尿病,使用d8601.5g/d,治疗后空腹血糖下降至4.67～7.3mmol/L。但口渴多饮症状未见好转,即来我院检查。每日饮... 详细信息

患者男,70岁,退休工人。1989年6月起多饮、多尿伴体重下降及全身乏力。外院查空腹血糖12.4～13.3mmol/L,尿糖(++++)。诊断为糖尿病,使用d8601.5g/d,治疗后空腹血糖下降至4.67～7.3mmol/L。但口渴多饮症状未见好转,即来我院检查。每日饮水量8000～10000ml,尿排量为7000～9000ml。以往无明显头痛及精神应激史,无头部外伤史。查体:神志清、两瞳孔等大、对光反射存在、无视野缺损、眼底(-)。皮肤干燥、心率76次/分、律齐、血

关键词：尿崩症代谢病尿比重特发性

宫内暴露于选择性5-羟色胺再摄取抑制剂后足月新生儿的戒断综合征

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世界核心医学期刊文摘（儿科学分册） 2006年第8期2卷 29-29页

作者： Levinson-Castiel r. Merlob P. Linder N. G.Klinger 俞晓梅 Neonatal Intensive Care Unit Schneider Children's Medical Center of Israel14 Kaplan StreetPetah Tiqwa49202Israel Dr.

Objective:To compare the prevalence and clinical characteristics of neonatal abstinence syndrome in neonates exposed and not exposed to selective serotonin r euptake inhibitors(SSrIs)in ***:Cohort ***:Tertiary car e ***:One hundred twenty term infants,of whom 60 had prolonged in utero exposure to SSrIs,including paroxetine hydrochloride,fluoxetine,citalo pram hydrobromide,sertraline hydrochloride,and venlafaxine *** Outcome Measures:Neonatal abstinence syndrome was assessed with the Finnegan s core as follows:score of 8 or above,severe;score of 4 to 7,mild;and score o f 0 to 3,*** infants were followed up with a standardized protocol that included repeated Finnegan score assessments and cardiorespiratory monitoring u ntil normalization of the Finnegan ***:Of the 60 neonates exposed to SSrIs in utero,8 showed severe and 10 showed mild symptoms of a neonatal absti nence *** nonexposed neonates had a normal Finnegan *** neonates who developed severe symptoms,the maximum mean daily Finnegan scores were reco rded within 2 days after birth,although maximum individual scores were recorded as long as 4 days after ***:Neonatal abstinence syndrome occurs in 30%of neonates exposed to SSrIs in *** neonates should be monitore d for at least 48 hours after *** longterm effects of prolonged exposure to SSrIs,particularly in neonates who develop severe symptoms,have yet to be d etermined.

关键词：选择性5-羟色胺再摄取抑制剂新生儿戒断综合征足月新生儿宫内暴露 SSrI 盐酸帕罗西汀盐酸万拉法新心肺监护盐酸舍曲林出生后