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Comparing accuracy of cochlear measurements on magnetic resonance imaging and computed tomography:A step towards radiation-free cochlear implantation

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中华耳科学杂志:英文版 2023年第4期18卷 208-213页

作者： Anurita Swarup Vinusree Karakkandy Preetam Chappity Suprava Naik Sanjay kumar Behera pradipta kumar parida Mohnish Grover Gaurav Gupta Prajna Paramita Giri Saurav Sarkar Pradeep Pradhan Dillip kumar Samal Aswathi Kallyadan Veetil Asutosh Adhikari Saurav Nayak Department of ENT and HNS All India Institute of Medical Sciences(AIIMS)BhubaneswarOdishaIndia Department of Radiodiagnosis All India Institute of Medical Sciences(AIIMS)BhubaneswarOdishaIndia Department of Community and Family Medicine All India Institute of Medical Sciences(AIIMS)BhubaneswarOdishaIndia Department of Biochemistry All India Institute of Medical Sciences(AIIMS)BhubaneswarOdishaIndia Department of ENT Sawai Man Singh Medical CollegeJaipurRajasthanIndia Department of ENT Sardar Patel Medical CollegeBikanerRajasthanIndia

Objective:Computed Tomography(CT)and Magnetic Resonance Imaging(MRI)are commonly employed in pre-operative evaluation for cochlear implant ***,with a decrease in the age of implantation,even minor radiation exposure can cause detrimental effects on children over their *** current study compares different cochlear measurements from CT and MRI scans and evaluates the feasibility of using only an MRI scan for radiological evaluation before cochlear ***:A longitudinal observational study was conducted on 94 ears/47 children,employing CT and MRI *** CT and MRI scan measurements include,A value,B value,Cochlear duct length(CDL),twoturn cochlear length,alpha and beta angles to look for cochlear *** nerve diameter was measured using *** values were ***:The mean difference between measurements from CT and MRI scans for A value,B value,CDL,and two-turn cochlear length values was 0.567±0.413 mm,0.406±0.368 mm,2.365±1.675 mm,and 2.063±1.477 mm respectively without any significant *** alpha and beta angle measures were comparable,with no statistically significant ***:The study suggests that MRI scans can be the only radiological investigation needed with no radiation risk and reduces the cost of cochlear implant program in the paediatric *** is no significant difference between the measurements obtained from CT and MRI ***,observed discrepancies in cochlear measurements across different populations require regionally or race-specific standardized values to ensure accurate diagnosis and precision in cochlear implant *** aspect must be addressed to ensure positive outcomes for patients.

关键词： Cochlear implant Hearing loss Cochlea anatomy Radiology

Submental island flap reconstruction for carcinoma of the oral cavity: Experience in 30 cases

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2019年第2期5卷 65-70页

作者： Pradeep Pradhan Swagatika Samal Dillip kumar Samal Chappity Preetam pradipta kumar parida Department of Otorhinolaryngology All India Institute of Medical SciencesBhubaneswarOdisha751019India Department of Pathology All India Institute of Medical SciencesBhubaneswarOdisha751019India

Objective:The submental flap can be utilized for soft tissue reconstruction in oral cavity malignancies because due to its close approximation to the surgical site,fewer donor site morbidity and the cost effectiveness of the ***:A total of 30 patients with squamous cell carcinoma of the oral cavity were included in the study from July 2012 to August 2015 in a tertiary care referral *** with clinical staging Ⅰ/Ⅱ/Ⅲ (T1/T2/T3,N0) oral malignancy were included in the *** with nodal metastasis irrespective of the stage of disease and patients with chronic medical illness/revision cases were excluded from the *** island flap was utilized for the reconstruction of the soft tissue defect in each *** were followed at monthly interval till 6 months in the postoperative ***:The buccal mucosa (12 patients),tongue (10 patients) and floor of mouth (8 patients) were the subsites in the oral *** and complete skin necrosis was found in 4 and 2 patients *** chemoradiation was required in 5 *** of the patients had loco regional recurrence till 6 months of ***:The submental island flap is considered to be the reliable option for the soft tissue reconstruction in oral cancer because of dependent vascular pedicle,less donor site morbidity and the lower cost compared to the free flaps,often preferred in patients with a lower socioeconomic condition.

关键词： Oral malignancies Submental island flap Surgical technique Outcome

Surgical management of extracranial nerve sheath tumours in a tertiary care center

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2019年第2期5卷 76-81页

作者： Pradeep Pradhan Chappity Preetam Swagatika Samal Dillip kumar Samal pradipta kumar parida Department of ENT and Head Neck Surgery All India Institute of Medical SciencesBhubaneswarOdisha751019India

Objective:Excision of the nerve sheath tumours of head and neck is always a challenge to the surgeon because of their close proximity of the neurovascular ***:It is a retrospective study contained 13 consecutive patients of nerve sheath tumours involving the head and neck from March 2013 to February 2017 in the department of Otorhinolaryngology and Head Neck Surgery in a tertiary care referral hospital The retrospective clinical data,diagnostic procedures,surgical approaches and their complications are analyzed after 12 months of ***:Total 13 patients,7 were females and 6 were *** neck swelling was the most common presentation found in 6 and the most common site of origin was the vagus nerve in the parapharyngeal space (6 patients).Transcervical excision of the tumour was performed in 7 *** needed combined surgical approach for the excision of the *** injury was detected in 3 patients,and one patient had recurrent disease during the follow-up ***:Excision of the nerve sheath tumours of head and neck is always a challenge to the surgeon because of their close proximity of the neurovascular *** the transcervical approach is commonly practiced for the majority of the tumours,combined approaches can be effectively applied for extensive nerve sheath tumours with the satisfactory clinical outcome.

关键词： Nerve sheath tumours Surgical management Outcome

Optimized protoplast isolation and transfection with a breakpoint:accelerating Cas9/sgRNA cleavage efficiency validation in monocot and dicot

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aBIOTECH 2024年第2期5卷 151-168页

作者： Debasmita Panda Subhasis Karmakar Manaswini Dash Swagat kumar Tripathy Priya Das Sagar Banerjee Yiping Qi Sanghamitra Samantaray pradipta kumar Mohapatra Mirza J.Baig Kutubuddin A.Molla ICAR National Rice Research Institute CuttackOdisha 753006India Department of Botany Ravenshaw UniversityCuttackOdisha 753003India Department of Plant Science and Landscape Architecture University of MarylandCollege ParkMD 20742USA

The CRISPR-Cas genome editing tools are revolutionizing agriculture and basic biology with their simplicity and precision ability to modify target genomic ***-predicted guide RNAs(gRNAs)often fail to induce efficient cleavage at target *** target loci are inaccessible due to complex chromatin ***,there is no suitable tool available to predict the architecture of genomic target sites and their ***,significant time and resources are spent on performing editing experiments with inefficient *** in vitro-cleavage assay could provide a rough assessment of gRNA efficiency,it largely excludes the interference of native genomic *** in-vivo testing gives a proper assessment of the cleavage ability of editing reagents in a native genomic ***,we developed a modified protocol that offers highly efficient protoplast isolation from rice,Arabidopsis,and chickpea,using a sucrose gradient,transfection using PEG(polyethylene glycol),and validation of single guide RNAs(sgRNAs)cleavage efficiency of *** have optimized various parameters for PEG-mediated protoplast transfection and achieved high transfection efficiency using our protocol in both monocots and *** introduced plasmid vectors containing Cas9 and sgRNAs targeting genes in rice,Arabidopsis,and chickpea *** dual sgRNAs,our CRISPRdeletion strategy offers straightforward detection of genome editing success by simple agarose gel *** sequencing of PCR products confirmed the editing efficiency of specific ***,we demonstrated that isolated protoplasts can be stored for up to 24/48 h with little loss of viability,allowing a pause between isolation and *** high-efficiency protocol for protoplast isolation and transfection enables rapid(less than 7 days)validation of sgRNA cleavage efficiency before proceeding with stable *** isolation and transfection method can als

关键词： Protoplast Genome editing Transgene-free edited plants Rice Chickpea

Incidence of exclusive extrapelvic skeletal metastasis in prostate carcinoma on bone scintigraphy

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World Journal of Radiology 2024年第7期16卷 265-273页

作者： Parneet Singh Kanhaiyalal Agrawal Ashique Rahman Tejasvini Singhal Girish kumar parida Gopinath Gnanasegaran Department of Nuclear Medicine All India Institute of Medical SciencesBhubaneshwar 751019OdishaIndia Department of Nuclear Medicine Royal Free HospitalLondon NW32QGUnited Kingdom

BACKGROUND Bone is one of the common sites of metastasis from prostate *** scintigraphy(BS)is one of the most sensitive imaging modalities currently used for bone metastatic *** metastasis in prostate carcinoma commonly involves pelvic bones but rarely involves extrapelvic-extraspinal *** To retrospectively analyze the BS data to determine the pattern of skeletal metastases in the prostate *** This retrospective observational study involves patients with biopsy-proven prostate carcinoma referred for BS for staging *** with abnormal BS were evaluated for the pattern of skeletal involvement and data were pre-sented in descriptive format in the form of *** A total of 150 patients with biopsy-proven prostate cancer who were referred for staging were included in the *** of 150 patients(8.67%)had no abnormal uptake on planar images,ruling out metastatic ***-four patients(16%)had heterogeneous uptake in the spine with distribution charac-teristic of degenerative disease and no scan pattern of metastatic *** patients(20%)had multifocal uptake involving both pelvic and extra pelvic bones on planar images typical for skeletal metastasis and were considered ***-three out of 150 patients(55.3%)had increased tracer uptake,which was indeterminate,thus,single photon emission computed tomography-computed tomography(SPECT-CT)was acquired,which showed 51 with metastatic disease,31 benign lesions,and one indeterminate *** of 150 patients had exclusive pelvic bone uptake,which was found to be metastatic in 4/7 patients in *** six out of 150 patients showed exclusive extrapelvic tracer uptake,of which only 3 had vertebral metastatic *** of the patients with increased uptake exclusively in the extrapelvic-extraspinal location was *** The incidence of exclusive extrapelvic skeletal metastatic disease in prostate carcinom

关键词： Pelvic Prostate cancer Bone scan Single photon emission computed tomography-computed tomography Skeletal metastasis

Short-term mixed electricity demand and price forecasting using adaptive autoregressive moving average and functional link neural network

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Journal of Modern Power Systems and Clean Energy 2019年第5期7卷 1241-1255页

作者： Sujit kumar DASH pradipta Kishore DASH Siksha O Anusandhan Deemed to be University Bhubaneswar 751030India

A new hybrid adaptive autoregressive moving average(ARMA)and functional link neural network(FLNN)trained by adaptive cubature Kalman filter(ACKF)is presented in this paper for forecasting day-ahead mixed short-term demand and electricity prices in smart *** hybrid forecasting framework is intended to capture the dynamic interaction between the electricity consumers and the forecasted prices resulting in the shift of demand curve in electricity *** proposed model comprises a linear ARMA-FLNN obtained by using a nonlinear expansion of the weighted *** nonlinear functional block helps introduce nonlinearity by expanding the input space to higher dimensional space through basis *** train the ARMA-FLNN,an ACKF is used to obtain faster convergence and higher forecasting *** proposed method is tested on several electricity markets,and the performance metrics such as the mean average percentage error(MAPE)and error variance are compared with other forecasting methods,indicating the improved accuracy of the approach and its suitability for a real-time forecasting.

关键词： Mixed demand and price forecasting Cubature Kalman filter Price spikes Smart grids

Analysis of some critical aspects in hot machining of Ti-5553 superalloy: Experimental and FE analysis

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Defence Technology（防务技术） 2019年第3期15卷 344-352页

作者： Asit kumar parida Kalipada Maity Mechanical Engineering Department Indian Institute of Technology Delhi India National Institute of Technology Rourkela Mechanical Engineering Department India

In this study, a newly developed titanium superalloy, i.e., the Ti-5553 alloy has used for hot machining. This material replaced Ti-grade-5 alloy in the application of aerospace, automobile, and biomedical sector. However, similar to Ti-grade-5 alloy, the Ti-5553 alloy has a low thermal conductivity which makes it difficult-to-cut material categories hence, high tool wear, cutting force and bad surface finish. Hot machining of Ti-5553 has been studied at different machining condition (room and hot) using Deform-2D finite element analysis. The result from the simulation test was compared with the experimental value and reduction of cutting and thrust forces was observed. The experiment was carried out with the same input parameters as simulation, and good coherence between them observed. Additionally, cutting zone temperature, effective stress, etc. for both room and elevated the temperature are also discussed.

关键词： Ti-5553 Hot machining Cutting force Flank wear Finite element analysis

FEM analysis and experimental investigation of force and chip formation on hot turning of Inconel 625

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Defence Technology（防务技术） 2019年第6期15卷 853-860页

作者： Asit kumar parida Kalipada Maity Indian Institute of Technology Delhi Department of Mechanical EngineeringIndia National Institute of Technology Rourkela Department of Mechanical EngineeringIndia

This study investigates the hot machining of Inconel 625 alloy by using flame heating under different machining conditions using finite element analysis(FEM).Turning tests are performed at different cutting speeds and heating temperatures using uncoated carbide insert by DEFORM *** reduction in cutting force and tool wear has achieved at heating conditions compared to room *** tool life is achieved at the highest cutting speed and higher heating temperature *** heating conditions of the 600℃ continuous chip is formed whereas at room temperature saw-tooth chip formation is observed.A significant agreement is achieved between simulated and experimental cutting forces and chip *** effect of feed rates and depth of cuts are also studied experimentally during turning of Inconel 625 in a systematic manner.

关键词： Hot machining Force Inconel 625 Surface roughness Chip morphology

Hybrid IWD-DE:A Novel Approach to Model Cooperative Navigation Planning for Multi-robot in Unknown Dynamic Environment

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Journal of Bionic Engineering 2019年第2期16卷 235-252页

作者： Degal Chandrasekhar Rao Manas Ranjan Kabat pradipta kumar Das Prabir kumar Jena Department of Information Technology VSSUTBurlaOdisha 768018India Department of Computer Science&Engineerings VSSUT、Burla Odisha 76801&India Department of Mechanical Engineering VSSUTBurlaOdisha 76801&India

The current study emphasizes inadequacies of earlier research findings on multi-robot navigation and offers a robust approach to guide the robots in an unknown dynamic *** attain the objective,the Intelligent Water Drop(IWD)algorithm is combined with Differential Evolution(DE)in a new conceptual fashion to optimize the navigation path of multiple mobile *** hybrid IWD-DE,basic IWD and DE algorithms are then explored for multi-robot navigation in a dynamic workspace through *** simulation outcomes demonstrate the competency of the proposed method to guide the robot in predicting the nature of the obstacle and to generate an optimal and safe trajectory in a dynamic *** potency of the proposed algorithm is further validated through experimentation with fire bird robot in a real *** outcomes of the simulation and experimentation,by employing IWD-DE algorithm are compared with those of basic IWD and DE *** error estimated for Average Navigation Path Travelled(ANPT),Aggregate Navigation Path Deviation(ANPD)and number of turns between simulation and experimental results by employing IWD-DE is 8.96,9.09,and 11.13,respectively while reaching 16.43,28.61,29.15 for IWD,and 6.66,10.20,14.28 for *** efficiency of the proposed approach is further verified with the state-of-the-art in a dynamic *** outcomes reveal the efficiency and flexibility of the proposed approach in resolving the multi-robot navigation problem as compared to the state-of-the-art in a dynamic workspace.

关键词： multi-robot dynamic environment intelligent water drop differential evolution navigation planning waypoints fire bird robot