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Wound healing activity of Delonix elata stem bark extract and its isolated constituent quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside in rats

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Journal of Pharmaceutical Analysis 2016年第6期6卷 389-395页

作者： pradeepa krishnappa Krishna Venkatarangaiah Venkatesh Santosh Kumar Shimoga Rajanna Rebijith Kayattukandy Balan Department of Post Graduate Studies and Research in Biotechnology Kuvempu University Department of Biotechnology MS Ramaiah Institute of Technology Department of Biochemistry Indian Institute of Science(IISc) Division of Biotechnology Indian Institute of Horticultural Research(IIHR)

Delonix elata *** a Ceasalpinaceae species and is traditionally used in India for treatment of skin diseases,liver diseases and rheumatic ***,systematic evaluation of its wound healing activity is ***,in the present study,we aimed to assess the wound healing activity of *** stem bark extract(DSE) and its isolated constituent quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside(QRPG) in *** formulations effects on wound healing were assessed by the wound contraction rate,epithelialization period,tensile strength,content of the hydroxyproline,hexosamine and uronic acid in granulation tissue,histopathological studies and Col 1 α(I) expression level in wound tissue by reverse transcription polymerase chain reaction(RT-PCR) *** topical application of DSE ointment caused faster epithelialization,significant wound contraction(100%),and better tensile strength(710.5 ± 10.5 g/cm^2),while QRPG showed wound epithelialization with 98.2%contraction,better than that of the control group(78.18%).The biochemical analysis of granulation tissue revealed that DSE and QRPG significantly increased hydroxyproline,hexosamine and uronic acid content.A significant increase in the expression of Col 1 α(I) was observed in the wound tissue of DSE and QRPG treated *** and QRPG were shown to enhance wound healing by increasing collagen synthesis through upregulation of Col 1 α(I),thus validating ethnomedicinal uses.

关键词： Delonix elata Quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside (QRPG) Wound healing Hydroxyproline Tensile strength

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Plasticized Polymer Electrolyte Membranes Based on PEO/PVdF-HFP for Use as an Effective Electrolyte in Lithium-ion Batteries

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Chinese Journal of Polymer Science 2017年第3期35卷 407-421页

作者： pradeepa prabakaran ramesh prabhu manimuthu sowmya gurusamy edwinraj sebasthiyan school of physics alagappa universityKaraikudi-630 004Tamil NaduIndia

Plasticized polymer electrolytes were prepared using poly（ethylene oxide）(PEO)/poly（vinylidene fluoridehexafluoro propylene）(PVd F-HFP) with lithium perchlorate（Li Cl O4） and different plasticizers. XRD and FTIR spectroscopic techniques were used to characterize the structure and the complexation of plasticizer with the host polymer matrix. The role of interaction between polymer hosts and plasticizer on conductivity is discussed using the results of alternating current（a.c.） impedance studies. TG-DTA and SEM were used for thermal and physical characterizations. Maximum ionic conductivity(3.26 × 10;S·cm;) has been observed for ethylene carbonate（EC）-based polymer electrolytes. Electrochemical performance of the plasticized polymer electrolyte is evaluated in LiFePO;/plasticized polymer electrolytes（PPEs）/Li coin cell. Good performance with low capacity fading on charge discharge cycling is demonstrated.

关键词： X-ray diffraction Impedance spectroscopy Atomic force microscopy Ionic conductivity Dielectrics

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Effects of ceramic filler in poly(vinyl chloride)/poly(ethyl methacrylate) based polymer blend electrolytes

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Chinese Chemical Letters 2015年第9期26卷 1191-1196页

作者： P.pradeepa S.Edwinraj M.Ramesh Prabhu School of Physics Alagappa University

Effects of nano-ceramic filler titanium oxide（TiO2） have been investigated on the ionic conductance of polymeric complexes consisting of polyvinyl chloride）（PVC）/poly（ethyl methacrylate）（PEMA）,and lithium perchlorate（LiClO4）.The composite polymer blend electrolytes were prepared by solvent casting *** TiO2 nanofillers were homogeneously dispersed in the polymer electrolyte matrix and exhibited excellent interconnection with PVC/PEMA/PC/UCIO4 polymer *** addition of TiO2nanofillers improved the ionic conductivity of the polymer electrolyte to some extent when the content of TiO2 is 15 wt%.The addition of TiO2 also enhanced the thermal stability of the *** changes in the structural and complex formation properties of the materials are studied by X-ray diffraction（XRD） and Fourier transform infrared spectroscopy（FTIR） *** scanning electron microscope image of nano-composite polymer electrolyte membrane confirms that the TiO2 nanoparticles were distributed uniformly in the polymer matrix.

关键词： Poly(vinyl chloride) Poly(ethyl methaerylate) Polymer composite electrolytes Nanofillers Ionic conductivity

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Predictive Value of the Neutrophil to Lymphocyte Ratio (NLR) to Predict the Development of Preeclampsia and Pregnancy Induced Hypertension at 1^st Trimester

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Open Journal of Obstetrics and Gynecology 2024年第4期14卷 547-559页

作者： pradeepa Sanjeewa Department of Obstetrics and Gynaecology Post Graduate Institute of Medicine University of Colombo Colombo Sri Lanka

Introduction: Hypertensive disorder in pregnancy affects 4 to 6 percent of all pregnancies and carries risks for the both baby and the mother. Only a few groups of women who are at high-risk pregnancies are received prophylaxis Aspirin, more than 15 percent of women develop pre-eclampsia with a single minor risk factor. Methods: This descriptive cross-sectional study was conducted to compare the 1st trimester NLR value of normotensive, pregnancy induced hypertensive and pre-eclamptic pregnant women. The study was conducted with a sample of 416, antenatal patients who were admitted to ward 25, at Colombo North Teaching Hospital Ragama. Data was collected as separated three groups. NLR value was calculated separately and ANOVA test was used to analyze the 3 categorical data. Post HOC test was done to assess the multiple comparison. Results: The prevalence rates of pregnancy induced hypertension and pre-eclampsia among the pregnant women were 8.6% and 5.7%. The mean NLR values of normotensive group was 2.708, pregnancy induced hypertensive group was 2.650 and pre eclamptic group was 3.789. There was a significant difference in NLR value between pre eclamptic group and other two groups with P value of Conclusion: The 1st trimester NLR value of pre eclamptic patients significantly increased compared to normotensive women.

关键词： Pre-Eclampsia Neutrophil to Lymphocyte Ratio 1st Trimester

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Grid power quality enhancement using an ANFIS optimized PI controller for DG

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Protection and Control of Modern Power Systems 2022年第1期7卷 26-39页

作者： Srishail K.Bilgundi R.Sachin H.pradeepa H.B.Nagesh M.V.Likith Kumar Department of Electrical and Electronics Engineering The National Institute of EngineeringMysuruKarnatakaIndia Department of Electrical and Electronics Engineering Bangalore Institute of TechnologyBangaloreKarnatakaIndia

Grid frequency variation causes phase angle deviation in current with respect to *** is sensed at the phase-locked loop in the *** past studies the effect of grid frequency variation is neglected while designing the controller for power quality *** modern grids are connected to large numbers of non-linear loads and various types of distributed generation(DG),it results in continuous variation in grid *** it is necessary to consider the grid frequency variation for effective power quality ***,tuning of conventional PI controller gains considering frequency variation is very *** it is necessary to develop an adaptive intelligent nonlinear controller to tackle the effects of frequency variation,voltage distortion and non-linear load *** paper presents the importance of considering the effects of the frequency variation,grid voltage distortion and non-linear load,while designing and deploying a controller for power quality *** proposed controller supplies power to local load as well as transferring surplus power to the grid from DG along with the additional ben-efit of improving grid power quality.A DG with an ANFIS optimized PI current controller for power quality enhance-ment is *** method is economical as it requires no additional *** are compared with PI,PI-RC and fuzzy current controllers to validate the effectiveness of the proposed controller.

关键词： Adaptive neuro fuzzy inference system(ANFIS) Fuzzy logic PI controller Distributed generation(DG) Proton exchange membrane fuel cells(PEMFC) Total harmonic distortion(THD)

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Dorsal onlay buccal mucosal graft urethroplasty for female urethral stricture:Techniques and outcomes

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Asian Journal of Urology 2024年第4期11卷 611-617页

作者： Vinod Kumar Prabhuswamy Harsha Hiriyur Somashekarappa pradeepa Melinamane Ganeshappa Kumar Prabhu Venkatesh Krishnamoorthy NU Hospitals PadmanabhanagarBangaloreKarnatakaIndia

ObjectiveFemale urethral stricture (FUS) accounts for about 4%–13% of cases of female bladder outlet obstruction. FUS was and is still managed by repeated dilatations and/or direct visual internal urethrotomy. There are many alternative options for reconstruction like buccal or vaginal mucosal graft urethroplasty. Our aim was to describe the technique of dorsal onlay buccal mucosal graft (BMG) urethroplasty for FUS and present the *** January 2014 and December 2021, 37 patients who underwent dorsal onlay BMG urethroplasty were included in the study. Their pre-operative diagnosis was confirmed with uroflowmetry, micturating cystourethrogram, urethral calibration, and on table cystoscopy. Bladder catheter was removed after 2 weeks. Patients were followed up at 3 months, 6 months, 1 year, and then annually with urine analysis, uroflowmetry, and post-void residual assessment. We defined success as a maximum flow rate (Q_(max)) above 15 mL/s without the need for an additional *** mean age of patients was 47.8 (standard deviation [SD] 11.3) years. Twenty patients had previously undergone urethral dilatations. The mean pre-operative Q_(max) was 7.79 (SD 3.73) mL/s. However, the mean Q_(max) improved to 23.20 (SD 8.25) mL/s after surgery. The mean post-void residual urine after surgery was 30.50 (SD 10.70) mL. This reduced from a mean value of 139.00 (SD 147.24) mL before surgery. The mean follow-up was 30.2 (SD 18.3, range 18–44) months. There was no post-operative incontinence. There were Clavien–Dindo Grade 1 complications in 6 out of 37 (16.2 %) patients during hospital stay. The only long-term complication was recurrence of stricture in 4 (10.8%) *** onlay BMG urethroplasty in females is a safe, effective technique which can avoid repeated painful dilatations and multiple urethrotomies. One should always consider reconstruction in FUS without any fear of incontinence.

关键词： Female urethral stricture Urethral dilatation Urethrotomy Dorsal onlay Buccal mucosal graft

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Adomian decomposition method for Hall and ion-slip effects on mixed convection flow of a chemically reacting Newtonian fluid between parallel plates with heat generation/absorption

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Propulsion and Power Research 2017年第4期6卷 296-306页

作者： Ch.Ram Reddy O.Surender Ch.Venkata Rao T.pradeepa Department of Mathematics National Institute of TechnologyWarangal 506004India Department of Mathematics National Institute of TechnologyMizoram 796012India

This paper analyzes the heat and mass transfer characteristics on mixed convective fully developed flow in an electrically conducting Newtonian fluid between vertical parallel *** chemical reaction,heat generation,Hall and ion-slip effects are taken into *** using similarity transformations the nonlinear governing equations are reduced into dimensionless form and hence solved using Adomian decomposition method(ADM).The influence of magnetic parameter,Hall parameter,ion-slip parameter,chemical reaction parameter,and heat generation/absorption parameter on non-dimensional velocities,temperature and concentration profiles are exhibited *** addition,the numerical data for skin friction,heat and mass transfer rates are shown in tabular form.

关键词： Mixed convection Heat generation/absorption Hall and ion-slip effects Chemical reaction Adomian decomposition method(ADM)

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羽芒菊叶子提取物与聚乙烯醇共混物的静电纺丝

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国际纺织导报 2018年第5期46卷 12-14页

作者： P.Ganesan P.pradeepa 王宏球(译) 于俊荣(校) PSG技术学院印度不详

在古代,羽芒菊叶子捣碎后的浆液常被涂在伤口处以加速伤口愈合。如今,通常采用水凝胶敷料垫作为对抗疾病的创伤敷料。研究旨在促进中草药型敷料的发展。静电纺丝是利用高压将聚合物溶液纺制成纳米纤维的一种纺丝技术。静电纺纤维类似于... 详细信息

在古代,羽芒菊叶子捣碎后的浆液常被涂在伤口处以加速伤口愈合。如今,通常采用水凝胶敷料垫作为对抗疾病的创伤敷料。研究旨在促进中草药型敷料的发展。静电纺丝是利用高压将聚合物溶液纺制成纳米纤维的一种纺丝技术。静电纺纤维类似于细胞外基质,已成功应用于药物释放与创伤敷料。采用聚乙烯醇(PVA)溶液与羽芒菊叶子甲醇提取液按质量比为80/20进行静电纺丝,并拍摄偏光显微镜(PLM)图片进行分析。从PLM图上可观察到纤维上微珠的形成。这是由于纺丝溶液中添加了羽芒菊叶子提取物所致,纯PVA静电纺丝纤维上并没有微珠形成。

关键词：羽芒菊提取物聚乙烯醇(PVA) 静电纺丝

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