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retrocaval ureter presenting at 6 years of age in a girl child e An extreme rarity

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Asian Journal of Urology 2016年第2期3卷 107-109页

作者： pradeep Kajal Kamal rattan Vijender Sangwan Namita Bhutani Department of Paediatric Surgery Pt BDS PGIMS RohtakHaryanaIndia Nirvana Diagnostic Centre RohtakHaryanaIndia Department of Pathology Pt BDS PGIMS RohtakHaryanaIndia

retrocaval ureter is one of the very rare congenital *** report a case of retrocaval ureter in a 6-year-old girl who presented with right flank pain and *** diagnosis was made on intravenous urography which showed typical“J”shape deformity in the proximal dilated ureter with moderate *** scan delineated the course of *** patient was operated and findings were *** ureter was transected near the pelvis and a pyeloureteric anastomosis with pre-caval transposition of the ureter was performed and the patient was discharged in fair health.

关键词： Hydronephrosis Pyeloureteric anastomosis retrocaval ureter

Additional notes on Conchomyces bursiformis(Agaricales),a rare monotypic agaric from India

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Studies in Fungi 2018年第1期3卷 1-6页

作者： Manoj Kumar A Bijeesh C Vrinda KB pradeep CK Jawaharlal Nehru Tropical Botanic Garden&research Institute PalodeThiruvananthapuram695562KeralaIndia

Ample quantities of a crepidotoid agaric were collected from an evergreen forest in Kerala State,India and subsequent morphological and molecular analysis based on nLSU sequence confirmed it as Conchomyces bursiformis.A reappraisal along with comprehensive description,photographs,and discussion of this rare monotypic agaric is provided.

关键词： Agaricus Crepidotus Kerala nLSU taxonomy

High Security Identity Tags Using Spiral resonators

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Computers, Materials & Continua 2016年第6期 187-197页

作者： Anju pradeep S.Mridula P.Mohanan School of Engineering Cochin University of Science and TechnologyKeralaIndia Department of Electronics Cochin University of Science and TechnologyKeralaIndia

A highly compact chipless tag based on Frequency coding technique using Spiral resonators is proposed in this *** are well known metamaterial structures and thus capable of sharp resonance,and hence Spiral resonators can serve as a good candidate for rF Identity *** bit capacity of the proposed tag is 10 bits per *** prototype of the tag is fabricated on a low-cost substrate of dielectric constant 4.4 and loss tangent *** overall dimension of tag is 15.4 x 3 x *** methods for reading the tags are also discussed in this *** for bit enhancement is also provided.

关键词： High security tag metamaterial spiral resonator reader antenna

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正确的标杆管理助您实现卓越绩效

中国认证认可 2012年第8期 30-32页

作者：普拉迪普·古塔pradeep.Gupta 席瓦·南迪瓦达Siva.Nandiwada 刘健(译)

许多组织无法利用标杆管理的过程来创造优异的商业绩效，究其原因，一则可能是他们对标杆管理过程的理解有限，二则可能是他们对标杆管理能产生的增值不太了解。

关键词：标杆管理绩效管理过程商业

Treatment Initiation among Patients with Multidrug resistant Tuberculosis in Bhopal District, India

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Journal of Tuberculosis research 2017年第4期5卷 237-242页

作者： Hemant Deepak Shewade Arun M. Kokane Akash ranjan Singh Manoj Verma Malik Parmar Sanjay Singh Chahar Manoj Tiwari Sheeba Naz Khan Mukesh Nagar Sanjai Kumar Singh pradeep Kumar Mehra Ajay M. V. Kumar International Union against Tuberculosis and Lung Disease (The Union) South-East Asia Office New Delhi India Department of Community Medicine and Family Medicine All India Institute of Medical Sciences (AIIMS) Bhopal India State TB cell Department of Health and Family Welfare Bhopal India World Health Organization Country Office in India New Delhi India International Union against Tuberculosis and Lung Disease (The Union) Paris France

revised national tuberculosis control programme in India has limited co-hort-wise information about what happens to patients diagnosed with multidrug resistant TB (MDr-TB). We determined the pre-treatment loss to follow-up (non-initiation of treatment by programme within 6 months of diagnosis) and time from diagnosis to treatment initiation in Bhopal district, central India (2014). Pre-treatment loss to follow-up was 13% (0.95 CI: 7%, 23%), not significantly different from the national estimates (18%) and median time to initiate treatment was seven days, lower than that reported elsewhere in the country. Bhopal was performing well with reference to time to treatment initiation in programmatic settings.

关键词： Multidrug-resistant Tuberculosis Operational research Pre-Treatment Attrition Diagnosis and Treatment Pathway Initial Loss to Follow-Up

radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry

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World Journal of Gastroenterology 2013年第36期19卷 6011-6019页

作者： rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart pradeep Bhandari Lesley Ann Smith robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat Department of Surgery and Interventional Science National Medical Laser Centre UCL Department Gastroenterology University College Hospital NHS Foundation Trust Department Gastroenterology Guy’s and St Thomas’ Hospitals NHS Trust Institute for Medical Informatics Oslo University Hospital Department Gastroenterology Royal Liverpool University Hospital Merseyside Department Gastroenterology Princess Alexandra Hospital Cosham Department Gastroenterology Bradford Royal Infirmary Bradford Department Gastroenterology Central Manchester University Hospital Department Gastroenterology Glasgow Royal Infirmary Department Gastroenterology Addenbrooke’s Hospital royal Infirmary Edinburgh

AIM:To report outcomes on patients undergoing radiofrequency ablation(rFA)for early oesophageal squamous neoplasia from a National ***:A Prospective cohort study from 8 tertiary referral centres in the United *** with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were *** lesions were removed by endoscopic mucosal resection(EMr)before *** initial rFA treatment,patients were followed up *** flat dysplasia was treated with rFA until complete reversal dysplasia(Cr-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or *** main outcome measures were Cr-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse ***:Twenty patients with squamous HGD/ESCC completed treatment *** patients(25%)had EMr before starting rFA ***-D was 50%at12 mo with a median of 1 rFA treatment,mean 1.5(range 1-3).Two further patients achieved Cr-D with repeat rFA after this *** per cent with Cr-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQr 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 *** patients(20%)required endoscopic dilatations for symptomatic structuring after *** of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per *** other 2 patients required only a single dilatation to achieve an adequate symptomatic *** patient developed cancer during follow up after end of treatment ***:The role of rFA in these patients re-mains *** our series 50%patients responded at12 *** figures are lower than limited published data.

关键词： Squamous neoplasia Oesophageal cancer Endoscopic mucosal resection High-grade dysplasia radiofrequency ablation

αKLOTHO and sTGFβr2 treatment counteract the osteoarthritic phenotype developed in a rat model

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Protein & Cell 2020年第3期11卷 219-226页

作者： Paloma Martinez-redondo Isabel Guillen-Guillen Noah Davidsohn Chao Wang Javier Prieto Masakazu Kurita Fumiyuki Hatanaka Cuiqing Zhong reyna Hernandez-Benitez Tomoaki Hishida Takashi Lezaki Akihisa Sakamoto Amy NNemeth Yuriko Hishida Concepcion rodriguez Esteban Kensaku Shojima Ling Huang Maxim Shokhirev Estrella Nunez-Delicado Josep MCampistol Isabel Guillen-Vicente Elena rodriguez-Inigo Juan Manuel Lopez-Alcorocho Marta Guillen-Vicente George Church pradeep reddy Pedro Guillen-Garcia Guang-Hui Liu Juan Carlos Izpisua Belmonte Gene Expression Laboratory Salk Institute for Biological Studies10010 North Torrey Pines RoadLa JollaCA 92037USA Wyss Institute for Biologically Inspired Engineering Harvard UniversityCambridgeMA 02115USA Department of Genetics Harvard Medical SchoolBostonMA 02115USA Integrative Genomics and Bioinformatics Core Salk Institute for Biological Studies10010 North Torrey Pines RoadLa JollaCA 92037USA Universidad Catolica San Antonio de Murcia(UCAM) Campus de los JeronimosNo 1351230107 GuadalupeSpain Hospital Clinic of Barcelona Career Villarroel17008036 BarcelonaSpain Department of Traumatology and research Unit Clinica CEMTRO28035 MadridSpain National Laboratory of Biomacromolecules CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Institute for Stem cell and regeneration Chinese Academy of SciencesBeijing 100101China Translational Medical Center for Stem Cell Therapy Shanghai East HospitalTongji University School of MedicineShanghai 200120China

Dear Editor,Homeostasis and repair are critical biological processes that allow for tissue and organ preservation and function in multicellular *** regulation and extension vary drastically across the animal kingdom,and mammals show limited tissue-specific regenerative capacity that declines with *** aging,articular cartilage is one of the tissues that undergo substantial changes in the matrix structure,molecular composition,metabolic activity,and mechanical properties(Loeser et al.2016).

关键词： aging treatment critical

Blood:血管系统变化可能会导致阿兹海默症

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现代生物医学进展 2017年第15期17卷 I0003-I0003页

作者： Zu-Lin Chen Alexey S. revenko pradeep Singh A. robert MacLeod Erin H. Norris Sidney Strickland Patricia and John rosenwald Laboratory of Neurobiology and Genetics The Rockefeller University New York NY Department of Antisense Drug Discovery Ionis Pharmaceuticals Inc. Carlsbad CA Patricia and John rosenwald Laboratory of Neurobiology and Genetics The Rockefeller University New York NY Department of Antisense Drug Discovery Ionis Pharmaceuticals Inc. Carlsbad CA Patricia and John rosenwald Laboratory of Neurobiology and Genetics The Rockefeller University New York NY Patricia and John rosenwald Laboratory of Neurobiology and Genetics The Rockefeller University New York NY and

随着人口老龄化的趋势不断上升，阿兹海默症的发病成为越来越重要的健康问题。最近，科学家们试图利用各种手段清除患者大脑中造成疾病的斑块，但是药物的结果往往不尽如人意。来自洛克菲勒大学的科学家们利用一项最新的技术对阿兹海默... 详细信息

随着人口老龄化的趋势不断上升，阿兹海默症的发病成为越来越重要的健康问题。最近，科学家们试图利用各种手段清除患者大脑中造成疾病的斑块，但是药物的结果往往不尽如人意。来自洛克菲勒大学的科学家们利用一项最新的技术对阿兹海默症发病的生物学机制进行了解。意想不到的是，他们发现了一种常见于血栓以及炎症反应中的血浆成分在一些患者体内也检查得到。这并不是第一次将阿兹海默症与心血管疾病联系在了一起。”有大量证据表明锻炼身体能够帮助维持血管的健康以及血流的稳定，同时也能够有效避免阿兹海默症的发生”，神经生物学家Sidney Strickland说道：”另外。我们知道阿兹海默症会影响血管系统，就像糖尿病那样，提高人们血管疾病的发生风险”。

关键词：血管系统心血管疾病健康问题人口老龄化生物学机制血浆成分炎症反应生物学家

采用SKATEr导管行膀胱造瘘在高危前列腺电切术中的作用

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新医学 2012年第9期43卷 635-637页

作者：温星桥叶春伟朱宝益蔡燚陶奕然王喻孙其鹏 pradeep Bikram Singh 中山大学附属第三医院泌尿外科 510630

目的:评价SKATEr一步法膀胱造瘘管在经尿道前列腺电切术(TUrP)中的作用及临床意义。方法:收集接受TUrP治疗的38例高危、大体积BPH患者临床资料,其中同时行SKATEr一步法膀胱造瘘术18例、不行膀胱造瘘术20例。比较两组手术时间、切除组织... 详细信息

目的:评价SKATEr一步法膀胱造瘘管在经尿道前列腺电切术(TUrP)中的作用及临床意义。方法:收集接受TUrP治疗的38例高危、大体积BPH患者临床资料,其中同时行SKATEr一步法膀胱造瘘术18例、不行膀胱造瘘术20例。比较两组手术时间、切除组织量、出血量、术后拔尿管时间、住院时间等指标。结果:两组患者的TUrP与膀胱造瘘术均顺利完成。膀胱造瘘组一步法膀胱穿刺造瘘手术时间(3.0±0.5)min。两组术中出血量、切除腺体体积相近(P>0.05),均无患者发生水中毒或其他前列腺电切综合征。膀胱造瘘组TUrP手术时间、术后拔除尿管时间以及住院时间均比非膀胱造瘘组明显缩短(P均rP术中应用一步法膀胱造瘘,效果良好,操作简便,术后恢复较快。

关键词：前列腺增生经尿道前列腺电切术耻骨上膀胱造瘘术高危患者