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Journal of Management Analytics 2022年第1期9卷 120-136页

作者： Kuldeep Chaudhary pradeep kumar Sudipa Chauhan Vijay kumar Department of Mathematics AIASAmity UniversityNoidaIndia

This paper addresses the problem of determining the optimal promotional policy for a diffusion model in a segment-specific market under the assumption that the additional demand of the new product also improves brand image in the form of goodwill of the *** model is framed with the assumption that the firm uses the mass and differentiated promotion effort for each *** differentiated promotional efforts target each market segment independently and the mass promotional effort reaches different segments with a fixed *** derive the optimal promotional effort policy for each segment using maximumprinciple and also analyze the stability of the dynamical system by constructing a Lyapunov function through the graph theoretic *** analysis gives a deep insight into how the promotional effort should be planned by the decision makers keeping in mind the financial constrains without hindering the promotional effort at the end of the planning period.

关键词： market-segmentation brand-image maximum-principle stability analysis graph theoretic approach

Improved thermoelectric property of cation-substituted CaMnO_3

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Chinese Physics B 2015年第9期24卷 542-547页

作者： pradeep kumar Subhash C.Kashyap Vijay kumar Sharma H.C.Gupta Department of Physics Shyam Lal CollegeUniversity of Delhi Department of Physics Indian Institute of Technology Delhi

Single-phase pristine and cation-substituted calcium manganite（Ca1-xBixMn1-yVyO3-δ） polycrystalline samples were synthesized by the solid state reaction technique. Their thermoelectric properties were measured by a set up that was designed and assembled in the laboratory. The Ca1-x BixMn1-yVyO3-δsample with x = y = 0.04 has shown a power factor（S^2σ） of 176 μW/m/K^2 at 423 K, which is nearly two orders of magnitude higher than that of the pristine sample（2.1 μW/m/K2）. The power factor of the substituted oxide remains almost temperature independent as the Seebeck coefficient increases monotonically with temperature, along with the simultaneous decrease in electrical resistivity which is attributed to enhanced electron density due to co-doping of bismuth and vanadium and grain boundary scattering. These cation-substituted calcium manganites can be used as a potential candidate for an n-type leg in a thermoelectric generator（module）.

关键词： thermoelectric materials solid state reaction Seebeck coefficient power factor

Role of MgF2 addition on high energy ball milled kalsilite:Implementation as dental porcelain with low temperature frit

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Journal of Advanced Ceramics 2014年第4期3卷 332-338页

作者： Pattem Hemanth kumar Abhinav SRIVASTAVA Vijay kumar Nandini JAISWAL pradeep kumar Vinay kumar SINGH Department of Ceramic Engineering Indian Institute of Technology(BHU)VaranasiIndia Department of Chemical Engineering Indian Institute of Technology(BHU)VaranasiIndia

Porcelain fused to metal(PFM)has received great attention over the last few years due to its importance in the ***(K_(2)O·Al_(2)O_(3)·SiO_(2))is a high thermal expansion porcelain,suitable for bonding to ***,kalsilite is a metastable phase which gets converted into crystalline leucite upon *** the current work feasibility of developing stable kalsilite phase,dispersion of MgF2 in it as an additive and using mechanochemical synthesis are *** fine dental material has been formulated by mixing prepared kalsilite with low temperature frit(LTF)in different *** crystalline phases evolved in fired powders are characterized by powder X-ray diffraction(XRD)*** with different ratio of LTF has been cold pressed and heat treated to examine its coefficient of thermal expansion(CTE),flexural strength,apparent porosity(AP),bulk density(BD)and *** indicate that MgF_(2) addition and high milling duration help in kalsilite *** also plays an important role in this stabilization,and at 1100℃single phase kalsilite formation is *** outcomes demonstrate that it is easily possible to synthesize a stable single phase kalsilite with desirable properties.

关键词： kalsilite porcelain fused to metal(PFM) dental ceramic mechanochemical synthesis thermal expansion X-ray diffraction(XRD)

Synthesis,antimicrobial evaluation and QSAR studies of 3-ethoxy-4-hydroxybenzylidene/4-nitrobenzylidene hydrazides

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Chinese Chemical Letters 2011年第11期22卷 1293-1296页

作者： Davinder kumar Archana Kapoor Ananda Thangadurai pradeep kumar Balasubramanian Narasimhan Department of Pharmaceutical Sciences Guru Jambheshwar University of Science and Technology Hisar 125001India Department of Pharmaceutical Chemistry Swamy Vivekanandha College of Pharmacy Tiruchengode 637205India Faculty of Pharmaceutical Sciences Maharshi Dayanand University Rohtak 124001India

A series of 3-ethoxy-4-hydroxybenzylidene/4-nitrobenzylidene hydrazides（1-20） was synthesized and tested for in vitro antimicrobial *** results of antimicrobial studies indicated that the compounds having dinitro,methoxy,hydroxy and nitro substituents on phenyl ring of the aromatic acids were most active *** QSAR investigation indicated the importance of the topological parameter,third order molecular connectivity index（~3x） in describing the antimicrobial activity of synthesized hydrazides.

关键词： Benzylidene hydrazides Synthesis Antimicrobial mt-QSAR LOO method

CFD modeling to study the effect of particle size on dispersion in 20l explosion chamber: An overview

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International Journal of Mining Science and Technology 2020年第3期30卷 321-327页

作者： Santosh kumar Ray Niroj kumar Mohalik Asfar Mobin Khan Debashish Mishra Nikhil kumar Varma Jai Krishna Pandey pradeep kumar Singh CSIR-Central Institute of Mining and Fuel Research Dhanbad 826001India

Mine disasters occur predominantly due to methane or coal dust explosion or a combination of *** the top ten worst coal mine disasters in India, nine are due to coal dust explosion. The current paper describes a general overview of the parameters causing dispersion leading to coal dust explosion,and computational fluid dynamics(CFD) simulation study to observe the effects of particle size on dispersion in Indian coal mines. Turbulent kinetic energy(TKE) and velocity vector path of dust-air mixture and dust-free air were simulated to understand their effects on coal dust dispersion. The TKE contours and velocity vector paths for dust-free air were uniform and symmetrical due to resistance-free path available. The TKE contours and velocity vector paths for dust-air mixture shows the asymmetrical distribution of contours, due to entrainment of air with dust particles. Vortices were observed in velocity vector paths which gradually diminish on increment of time sequence. These vortices are dead centres where velocity and coal dust particles concentration are both zero.

关键词： Coal dust explosibility CFD 20l explosion chamber Dispersion Turbulent kinetic energy

Free Vibration Analysis of RC Box-Girder Bridges Using FEM

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Sound & Vibration 2022年第2期56卷 105-125页

作者： Preeti Agarwal Priyaranjan Pal pradeep kumar Mehta Motilal Nehru National Institute of Technology Allahabad Prayagraj211004India

The free vibration analysis of simply supported box-girder bridges is carried out using the finite element *** fundamental frequency is determined in straight,skew,curved and skew-curved box-girder *** is important to analyse the combined effect of skewness and curvature because skew-curved box-girder bridge behaviour cannot be predicted by simply adding the individual effects of skewness and *** first,an existing model is considered to validate the present approach.A convergence study is carried out to decide the mesh size in the finite element *** exhaustive parametric study is conducted to determine the fundamental frequency of box-girder bridges with varying skew angle,curve angle,span,span-depth ratio and cell *** skew angle is varied from 0°to 60°,curve angle is varied from 0°to 60°,span is changed from 25 to 50 m,span-depth ratio is varied from 10 to 16,and single cell&double cell are used in the present study.A total of 420 bridge models are used for parametric study in the *** shapes of the skew-curved bridge are also *** fundamental frequency of the skew-curved box-girder bridge is found to be more than the straight bridge,so,the skew-curved box-girder bridge is *** present study may be useful in the design of box-girder bridges.

关键词： Fundamental frequency skew-curved box-girder bridge single-cell double-cell curve angle skew angle FEM

Protecting against different subtypes of influenza viruses:a nanoparticle approach

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Signal Transduction and Targeted Therapy 2020年第1期5卷 1982-1983页

作者： Changhua Yi Yongxiang Yi Junwei Li pradeep kumar Sacitharan Department of Infectious Diseases The Second Hospital of NanjingThe Affiliated Hospital of Nanjing University of Chinese Medicine#1 Zhongfu RoadNanjingJiangsu ProvinceChina Public Health and Therapy Center of Nanjing 211113 NanjingChina Department of General Surgery The Second Hospital of NanjingThe Affiliated Hospital of Nanjing University of Chinese Medicine#1 Zhongfu RoadNanjingJiangsu ProvinceChina College of Veterinary Medicine Qingdao Agricultural University266109 QingdaoChina The Institute of Ageing and Chronic Disease University of LiverpoolLiverpool L78TXUK Department of Biological Sciences Xi’an Jiaotong-Liverpool University#111 Ren’ai RoadSuzhou Industrial Park215123 SuzhouJiangsu ProvinceChina

A recent article by Wang et *** synthesized new nanoparticles consisting of cyclic guanosine monophosphate–adenosine monophosphate(cGAMP),which were administered alongside vaccines,to successfully deliver into the lungs of animals leading to protection against different subtypes of influenza infection without inflammatory side effects.

关键词： nanoparticle approach guanosine

Feature Selection with Deep Reinforcement Learning for Intrusion Detection System

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Computer Systems Science & Engineering 2023年第9期46卷 3339-3353页

作者： S.Priya K.pradeep Mohan kumar Department of Computer Science and Engineering SRM Institute of Science and TechnologyRamapuramChennai600089India Department of Computing Technologies SRM Institute of Science and TechnologyKattankulathurChennai603203India

An intrusion detection system(IDS)becomes an important tool for ensuring security in the *** recent times,machine learning(ML)and deep learning(DL)models can be applied for the identification of intrusions over the network *** resolve the security issues,this paper presents a new Binary Butterfly Optimization algorithm based on Feature Selection with DRL technique,called BBOFS-DRL for intrusion *** proposed BBOFSDRL model mainly accomplishes the recognition of intrusions in the *** attain this,the BBOFS-DRL model initially designs the BBOFS algorithm based on the traditional butterfly optimization algorithm(BOA)to elect feature ***,DRL model is employed for the proper identification and classification of intrusions that exist in the ***,beetle antenna search(BAS)technique is applied to tune the DRL parameters for enhanced intrusion detection *** ensuring the superior intrusion detection outcomes of the BBOFS-DRL model,a wide-ranging experimental analysis is performed against benchmark *** simulation results reported the supremacy of the BBOFS-DRL model over its recent state of art approaches.

关键词： Intrusion detection security reinforcement learning machine learning feature selection beetle antenna search

Low-dose metformin and PEN2-dependent lysosomal AMPK activation: benefits outnumber side effects

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Signal Transduction and Targeted Therapy 2022年第7期7卷 2119-2120页

作者： Longlong Liu pradeep kumar Patnana Subbaiah Chary Nimmagadda Department of Medicine A HematologyOncology and PneumologyUniversity Hospital MuensterMuensterGermany

Recent advances demonstrated numerous molecular mechanisms of metformin based on the dosage and duration,yet our understanding is *** a photoactive metformin probe Ma et al.1 identified presenilin enhancer 2(PEN2)as its interaction partner and demonstrated its contribution to AMP-activated protein kinase(AMPK)activation.1 Metformin is a widely used anti-diabetic for managing blood glucose levels in patients with type 2 diabetes mellitus(T2D).Owing to its pleiotropic modes of action,its role in other pathophysiological conditions including metabolic complications,cancer,cardiovascular diseases,inflammation,ageing,gut microbiota,neuroprotection and COVID-19 were *** is widely accepted that metformin inhibits mitochondrial complex I of the electron transport chain and results in a decrease in ATP synthesis stimulating AMPK,inhibiting hepatic gluconeogenesis,increasing insulin sensitivity in the liver and intensifying glucose absorption in the muscles.

关键词： dosage inflammation cardiovascular

Primary endoscopic stapedotomy using 3 mm nasal endoscope:Audiologic and clinical outcomes

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Journal of Otology 2020年第4期15卷 133-137页

作者： pradeep Pradhan Chappity Preetam Pradipta kumar Parida Department of ENT and Head Neck Surgery All India Institute of Medical SciencesBhubaneswarOdisha751019India

Objective:To report the use of a 3 mm rigid nasal endoscope in primary endoscopic stapedotomy and clinical and audiological *** and methods:Thirty patients diagnosed with primary otosclerosis underwent endoscopic stapedotomy that was performed using a 3 mm nasal endoscope(Karl Storz).At 6 months follow-up,the patients were evaluated for intraoperative findings,postoperative hearing outcomes and ***:Canaloplasty was performed in 2(6.66%)patients,and no curettage of the canal wall was required in 12(40%)*** of the chorda tympani nerve was conducted in 11(36.66%)*** average duration of surgery was 36 min(range 31e65 min).The air-bone gap(ABG)was 35 dB(range 24e50 dB)preoperatively and 14.63 dB(range 9e20 dB)postoperatively(p?0.00).At 6 months follow-up,<20 dB ABG was achieved in 93.33%of the *** major intraoperative/postoperative complications were ***:A 3 mm rigid nasal endoscope can be effectively used in stapedotomy to obtain adequate audiological *** can be considered as a better alternative to the standard microscope or 4 mm endoscope in preserving the posterior canal wall and chorda tympani nerve while minimizing operative time without causing significant complications.

关键词： Endoscope Otosclerosis Outcomes