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Analytical solution for the effective elastic properties of rocks with the tilted penny-shaped cracks in the transversely isotropic background

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Petroleum Science 2024年第1期21卷 221-243页

作者： Zheng-Qian Ma Xing-yao Yin Zhao-Yun Zong Yuan-Yuan Tan ya-Ming yang National Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao266580ShandongChina School of Geosciences China University of Petroleum(East China)Qingdao 266580ShandongChina Pilot National Laboratory for Marine Science and Technology(Qingdao) Qingdao266200ShandongChina

Seismic prediction of cracks is of great significance in many disciplines,for which the rock physics model is ***,up to now,multitudinous analytical models focus primarily on the cracked rock with the isotropic background,while the explicit model for the cracked rock with the anisotropic background is rarely investigated in spite of such case being often encountered in the ***,we first studied dependences of the crack opening displacement tensors on the crack dip angle in the coordinate systems formed by symmetry planes of the crack and the background anisotropy,respectively,by forty groups of numerical *** on the conclusion from the experiments,the analytical solution was derived for the effective elastic properties of the rock with the inclined penny-shaped cracks in the transversely isotropic ***,we comprehensively analyzed,according to the developed model,effects of the crack dip angle,background anisotropy,filling fluid and crack density on the effective elastic properties of the cracked *** analysis results indicate that the dip angle and background anisotropy can significantly either enhance or weaken the anisotropy degrees of the P-and SH-wave velocities,whereas they have relatively small effects on the SV-wave velocity ***,the filling fluid can increase the stiffness coefficients related to the compressional modulus by reducing crack compliance parameters,while its effects on shear coefficients depend on the crack dip *** increasing crack density reduces velocities of the dry rock,and decreasing rates of the velocities are affected by the crack dip *** comparing with exact numerical results and experimental data,it was demonstrated that the proposed model can achieve high-precision estimations of stiffness ***,the assumption of the weakly anisotropic background results in the consistency between the proposed model and Hudson's published theory for the or

关键词： Effective elastic property Tilted crack Transverse isotropy Analytical solution Crack opening displacement

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Trade-off analyses between food provision and soil conservation service of Grain for Green program in Mountainous Area

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International Soil and Water Conservation Research 2024年第1期12卷 43-53页

作者： yawen Li Yuxiang Li Xingwu Duan Zhongyin Cai ya Li Baiyun He Long Yin Institute of International River and Eco-security Yunnan UniversityKunming650091PR China Yunnan Key Laboratory of International Rivers and Trans-boundary Eco-security Kunming650091PR China State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing100085PR China University of Chinese Academy of Sciences Beijing100049PR China

The Grain for Green program and soil and water conservation engineering initiatives are crucial for controlling erosion in steep-slope ***,it is still unclear how these two management methods should be carried out in respect to the situation in mountainous ***,taking a typical mountainous area in southwest China as an example,we simulated six scenarios in order to compare the food provisioning service(FPS)and soil conservation service of the Grain for Green program(converting to grassland)and Construction Measures(converting to sloping terrace)under different *** showed that when farmland with a>25°slope was converted into grassland,the amount of soil erosion(M)decreased by 21.0%,while FPS decreased by only 0.7%.However,when farmland with a>25°slope was converted into sloping terrace,M decreased by 31.3%while FPS increased by 18.7%.With the increases of farmland slope ranges in the Construction Measures scenario,M gradually decreased and FPS gradually *** when farmland>15°was converted into sloping terrace,M decreased by 63.9%and FPS increased by 52.7%.Furthermore,the trade-offs of Construction Measures are lower than that of Grain for Green on different slope ***,we conclude that Construction Measures are a more suitable method in mountainous areas than the Grain for Green,and we suggest that further research be conducted to consider the ecological risks of construction engineering measures.

关键词： Soil erosion Grain for green Construction measures Mountainous areas

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Exploring mechanism of hidden,steep obliquely inclined bedding landslides using a 3DEC model:A case study of the Shanyang landslide in Shaanxi province,China

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China Geology 2024年第2期7卷 303-314,I0001-I0003页

作者： Jia-yun Wang Zi-long Wu Xiao-ya Shi Long-wei yang Rui-ping Liu Na Lu Xi’an Center of China Geological Survey/Northwest China Center for Geoscience Innovation Xi’an 710119China Xi’an University of Science and Technology Xi’an 710054China Wuhan Design&Research Institute Co. Ltd.of China Coal Technology&Engineering GroupWuhan 430064China

Catastrophic geological disasters frequently occur on slopes with obliquely inclined bedding structures(also referred to as obliquely inclined bedding slopes),where the apparent dip sliding is not readily *** phenomenon has become a focal point in landslide ***,there is a lack of studies on the failure modes and mechanisms of hidden,steep obliquely inclined bedding *** study investigated the Shanyang landslide in Shaanxi province,*** field investigations,laboratory tests of geotechnical parameters,and the 3DEC software,this study developed a numerical model of the landslide to analyze the failure process of such *** findings indicate that the Shanyang landslide primarily crept along a weak interlayer under the action of *** landslide,initially following a dip angle with the support of a stable inclined rock mass,shifted direction under the influence of argillization in the weak interlayer,moving towards the apparent dip *** slide resistance effect of the karstic dissolution zone was increasingly significant during this process,with lateral friction being the primary resistance force.A reduction in the lateral friction due to karstic dissolution made the apparent dip sliding characteristics of the Shanyang landslide more ***,deformations such as bending and uplift at the slope’s foot suggest that the main slide resistance shifts from lateral friction within the karstic dissolution zone to the slope foot’s resistance force,leading to the eventual buckling failure of the *** study unveils a novel failure mode of apparent dip creep-buckling in the Shanyang landslide,highlighting the critical role of lateral friction from the karstic dissolution zone in its failure *** insights offer a valuable reference for mitigating risks and preventing disasters related to obliquely inclined bedding landslides.

关键词： Landslide Steep obliquely inclined bedding slope Failure mode Failure mechanism Apparent dip creep-buckling Lateral friction 3DEC model Landslide numerical model Geological hazards survey engineering

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Role of lipids in the control of autophagy and primary cilium signaling in neurons

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Neural Regeneration Research 2024年第2期19卷 264-271页

作者： María Paz Hernández-Cáceres Daniela Pinto-Nuñez Patricia Rivera Paulina Burgos Francisco Díaz-Castro Alfredo Criollo Maria Jose yañez Eugenia Morselli Instituto de Investigación en Ciencias Odontológicas(ICOD) Facultad de OdontologíaUniversidad de ChileSantiagoChile Department of Basic Sciences Faculty of Medicine and ScienceUniversidad San SebastiánSantiagoChile Physiology Department Faculty of Biological SciencesPontificia Universidad Católica de ChileSantiagoChile Advanced Center for Chronic Diseases(ACCDiS) Facultad de Ciencias Químicas y Farmacéuticas&Facultad de MedicinaUniversidad de ChileSantiagoChile Autophagy Research Center SantiagoChile

The brain is,after the adipose tissue,the organ with the greatest amount of lipids and diversity in their composition in the human *** neurons,lipids are involved in signaling pathways controlling autophagy,a lysosome-dependent catabolic process essential for the maintenance of neuronal homeostasis and the function of the primary cilium,a cellular antenna that acts as a communication hub that transfers extracellular signals into intracellular responses required for neurogenesis and brain development.A crosstalk between primary cilia and autophagy has been established;however,its role in the control of neuronal activity and homeostasis is barely *** this review,we briefly discuss the current knowledge regarding the role of autophagy and the primary cilium in *** we review the recent literature about specific lipid subclasses in the regulation of autophagy,in the control of primary cilium structure and its dependent cellular signaling in physiological and pathological conditions,specifically focusing on neurons,an area of research that could have major implications in neurodevelopment,energy homeostasis,and neurodegeneration.

关键词： autophagic flux cholesterol fatty acids GPCR lysosomal storage diseases neurons NPC1 phosphoinositides primary cilium

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高技术产业集聚与城市碳生产率——基于绿色创新视角

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技术经济与管理研究 2024年第1期 37-42页

作者：刘亚芬韩志非郭雅琼内蒙古农业大学内蒙古呼和浩特010010

选取2011—2021年中国282个地级及以上城市面板数据,构建空间滞后模型和中介效应模型,实证检验高技术产业集聚对城市碳生产率的影响和传导机制。结果表明:高技术产业集聚不仅显著促进城市碳生产率提升,而且对邻近城市碳生产率具有正向... 详细信息

选取2011—2021年中国282个地级及以上城市面板数据,构建空间滞后模型和中介效应模型,实证检验高技术产业集聚对城市碳生产率的影响和传导机制。结果表明:高技术产业集聚不仅显著促进城市碳生产率提升,而且对邻近城市碳生产率具有正向空间溢出效应;高技术产业集聚对城市碳生产率的影响存在异质性特征,具体表现为对东部和中部地区城市、大城市和中心城市碳生产率提升的促进作用更强;绿色创新是高技术产业集聚促进城市碳生产率提升的关键途径。由此,政府应统筹推进高技术产业集聚、实施差异化产业发展战略、加大绿色创新扶持力度,充分释放高技术产业集聚对城市碳生产率的助推效应。

关键词：高技术产业集聚绿色创新城市碳生产率低碳经济

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慢性病共病患者社区卫生服务的选择偏好研究

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中国全科医学 2024年第4期27卷 454-459,467页

作者：魏李芳张玲谭娅罗秀成都医学院护理学院四川省成都市610083 成都医学院大健康与智能工程学院四川省成都市610500

背景随着中国老龄化进程不断加快,慢性病共病成为威胁全民健康的重大公共问题,在当前“健康中国2030”的大背景下,慢性病共病患者的健康管理问题亟待解决。目的了解影响慢性病共病患者选择社区卫生服务的偏好,探讨慢性病共病患者的支付... 详细信息

背景随着中国老龄化进程不断加快,慢性病共病成为威胁全民健康的重大公共问题,在当前“健康中国2030”的大背景下,慢性病共病患者的健康管理问题亟待解决。目的了解影响慢性病共病患者选择社区卫生服务的偏好,探讨慢性病共病患者的支付意愿(WTP),对现有慢性病的社区卫生服务体系提供改善建议。方法随机选取2022年5—8月成都市8家社区卫生服务中心的慢性病共病患者作为调查对象。通过现场问卷调查的方式收集慢性病共病患者的一般资料和离散选择实验偏好相关问题。根据共病不同类型将2型糖尿病合并高血压、高血压合并冠心病、2型糖尿病合并高血压及冠心病分别定义为Ⅰ类患者、Ⅱ类患者、Ⅲ类患者。采用混合Logit模型对慢性病共病患者社区卫生服务选择偏好进行回归分析,并量化分析慢性病共病患者对社区卫生服务的WTP。结果共发放调查问卷360份,回收有效问卷296份,有效回收率为82.2%。Ⅰ类患者(β=3.260,95%CI=2.610~3.910)、Ⅱ类患者(β=3.697,95%CI=2.612~4.781)及Ⅲ类患者(β=3.220,95%CI=2.271~4.169)均最看重药品可及性高的服务,其次为预约转诊服务和中医药提供服务。关于医生类型和长处方服务,Ⅰ类患者(β=0.971,95%CI=0.585~1.357)和Ⅱ类患者(β=0.686,95%CI=0.176~1.197)均更偏好处方时间更长的服务,而Ⅲ类患者(β=0.804,95%CI=0.196~1.413)更偏好全科医生提供服务。Ⅰ类患者(β=-0.049,95%CI=-0.057~-0.041)、Ⅱ类患者(β=-0.040,95%CI=-0.051~-0.029)和Ⅲ类患者(β=-0.037,95%CI=-0.048~-0.027)均更偏好自付费用更低的服务。不同慢性病共病类型患者WTP的回归分析结果显示,3类患者的WTP均与其对各个属性的偏好程度有关,其中Ⅰ类患者、Ⅱ类患者、Ⅲ类患者均对药品可及性高水平的WTP最高,分别为66.77、91.97、85.95元/月。结论慢性病共病患者对纳入的6个属性(医生类型、中医药提供服务、长处方服务、药品可及性、预约转诊及月自付费用)均有显著偏好。药品可及性是影响慢性病共病患者卫生服务选择偏好最重要的属性。建议精准定位患者需求,健全预约转诊,制定社区慢性病共病管理标准,加快中医药融入社区慢性病共病防治。

关键词：慢性病共病社区卫生服务偏好离散选择实验

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针对遮挡物体的轮廓细化实例分割

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中国图象图形学报 2024年第5期29卷 1221-1232页

作者：李伟黄娅张馨渊韩贵金西安邮电大学自动化学院西安710121

目的遮挡物体实例分割效果的好坏与物体轮廓的预测结果息息相关,但目前算法预测的物体轮廓并不够细化,使得分割掩膜粗糙,物体边界分割效果不佳。为此,以BCNet(bilayer convolutional network)网络为基础,提出一种针对遮挡物体的轮廓细... 详细信息

目的遮挡物体实例分割效果的好坏与物体轮廓的预测结果息息相关,但目前算法预测的物体轮廓并不够细化,使得分割掩膜粗糙,物体边界分割效果不佳。为此,以BCNet(bilayer convolutional network)网络为基础,提出一种针对遮挡物体的轮廓细化实例分割算法,预测的物体轮廓更加精细,分割掩膜更加完整。方法 1)提出一种均衡池化注意力模块来提取特征,在传统一维平均池化的基础上,增加一维最大池化操作以突出细节特征,并将最大池化和平均池化结果进行加权融合来提取特征,使提取的特征能更好地兼顾物体的整体和边缘细节;2)将BCNet掩膜头中轮廓预测与掩膜预测分成两个支路来进行,从特征金字塔最高分辨率特征中提取感兴趣区域(region of interest, RoI)特征用于轮廓预测,并提出一种自适应特征融合模块,将轮廓预测支路中的特征与掩膜预测支路的特征进行融合,在轮廓预测支路中,融合掩膜预测支路的特征可以更好地判定轮廓所属物体类别,在掩膜预测支路,融合轮廓预测支路的特征能够更好地辅助掩膜定位。结果在COCO 2017(common objects in context 2017)数据集上,本文相较于目前同类网络中性能最优的BCNet网络,在骨干网络为ResNet-50/101(deep residual network)时平均精度(average precision,AP)分别提高了1.7%和2.1%。结合可视化结果,本文分割算法对遮挡物体的轮廓分割更加精细,能有效分割出更加完整、精细的掩码。结论提出的针对遮挡物体的轮廓细化实例分割算法,明显提升了遮挡物体实例分割的效果。

关键词：遮挡物体实例分割均衡池化注意力模块(BPAM) 自适应特征融合模块(AFFM) BCNet 轮廓预测支路掩膜预测支路

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沟槽对液固两相湍流中展向涡结构影响的实验研究

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船舶力学 2024年第9期28卷 1368-1379页

作者：葛雅馨孙姣高天达陈文义严冬河北工业大学化工学院天津300130 河北工业大学化工节能过程集成与资源利用国家地方联合工程实验室天津300130

采用粒子图像测速技术(particlesimage velocimetry,PIV)研究沟槽对含有355μm聚苯乙烯颗粒的液固两相湍流边界层的影响规律,通过对比流过沟槽壁面与光滑平板含颗粒流的平均速度剖面、湍流度及雷诺切应力等湍流统计量,分析沟槽对两相湍... 详细信息

采用粒子图像测速技术(particlesimage velocimetry,PIV)研究沟槽对含有355μm聚苯乙烯颗粒的液固两相湍流边界层的影响规律,通过对比流过沟槽壁面与光滑平板含颗粒流的平均速度剖面、湍流度及雷诺切应力等湍流统计量,分析沟槽对两相湍流边界层特性的影响。采用空间多尺度、局部平均结构函数和λci涡量识别准则准确识别发卡涡展向涡的涡心,并提取周围脉动速度及流线的空间拓扑结构,对不同法向高度处顺向涡的数量规律进行统计分析。结果发现:与光滑平板相比,沟槽壁面平均速度剖面缓冲层部分抬升,对数区外移,壁面摩擦速度和摩擦切应力变小,表现出4.86%的减阻效果;在同一法向高度,相较于光滑壁面,沟槽壁面下检测到的顺向涡结构倾角较小,数量也较少,周围流向脉动速度较弱,说明在两相流中沟槽壁面能够削弱发卡涡的强度和发生可能,达到减阻的效果。

关键词：沟槽壁面两相流粒子图像测速湍流边界层展向涡

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Gastric cancer liver metastasis will reduce the efficacy of immunotherapy

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World Journal of Gastrointestinal Surgery 2024年第9期16卷 2760-2764页

作者： Liang Wang Shan-Shan Liu Sheng-Mei Zhang Xiao-Qian Chen Tao Huang Rong Tian ya-Qi Zhao Zhou Chen Cai-Rang Xianba Department of Gastrointestinal Oncology Surgery The Affiliated Hospital of Qinghai University&Affiliated Cancer Hospital of Qinghai UniversityXining 810000Qinghai ProvinceChina Intensive Care Unit The Affiliated Hospital of Qinghai University&Affiliated Cancer Hospital of Qinghai UniversityXining 810000Qinghai ProvinceChina Department of Ultrasound The Affiliated Hospital of Qinghai University&Affiliated Cancer Hospital of Qinghai UniversityXining 810000Qinghai ProvinceChina Department of General Surgery Hainan State People's Hospital of Qinghai ProvinceHainan Tibetan Autonomous Prefecture 813000Qinghai ProvinceChina

Immune checkpoint inhibitors augment the antitumor activity of T cells by inhibiting the negative regulatory pathway of T cells,leading to notable efficacy in patients with non-small cell lung cancer,melanoma,and other malignancies through immunotherapy ***,secondary malignant liver tumors not only lower the liver's sensitivity to immunotherapy but also trigger systemic immune suppression,resulting in reduced overall effectiveness of immune *** receiving immunotherapy for non-small cell lung cancer and melanoma experience reduced response rates,progression-free survival,and overall survival when secondary malignant tumors develop in the *** Liu's retrospective analysis,valuable insights are provided for the future clinical management of these ***,in patients with gastric cancer(GC),the occurrence of liver metastasis might be indicative of reduced efficacy of *** liver immune tolerance mechanisms and their negative impacts allows for the potential benefits of immunotherapy in patients with GC and liver *** Gastric cancer(GC)ranks among the prevalent malignancies affecting the digestive system *** on the latest epidemiological data[1,2],it holds the fifth position for incidence and the fourth position for mortality among all malignant *** cases and fatalities in China make up roughly half of the worldwide *** investigations[3]have demonstrated that the median overall survival(mOS)among advanced GC patients left untreated typically ranges from 3 to 4 *** chemotherapy recipients often experience a mOS of around one year,accompanied by a marked improvement in the quality of life among patients with advanced *** mainstay of treatment for advanced GC patients involves chemotherapeutic medications such as fluoropyrimidines,platinum compounds,and ***,their efficacy in tumor control is constrained by acquired resistance and pr

关键词： Immune checkpoint inhibitors Gastric cancer Gastric cancer with liver metastasis Immunotherapy Liver immune tolerance

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Effect of diluents on the extraction of praseodymium and samarium by Cyanex 923 from acidic nitrate medium

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Journal of Rare Earths 2010年第2期28卷 215-220页

作者： ya El-Nadi Hot Laboratories Centre Atomic Energy Authority(Egypt)

The solvent extraction of pr(Ⅲ) and Sm(Ⅲ) with trialkyl phosphine oxide(Cyanex 923) in chloroform,carbon tetrachloride,n-octane,cyclohexane,1,2-dichloroethane,benzene,toluene,xylene and nitrobenzene from acidic nitrate medium was *** the basis of slope analysis data,the composition of the extracted species was determined as(M(NO3)3?2CY923),CY923 refers to Cyanex *** values of the equilibrium constants and the separation factors were *** effect of the diluents on the metal extracti...

关键词： extraction diluents praseodymium samarium Cyanex 923 rare earths

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