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A Bayesian Network Approach for Offshore Risk Analysis Through linguistic Variables

China Ocean Engineering 2007年第3期21卷 371-388页

作者： Ren j. Wang j. j.nkinson I. Xu D. l. Yang j. B. School of Engineering Liverpool John Moores University Liverpool L 3 3 AF UK Manchester Business School The University of Manchester Manchester M 60 1 QD UK

This paper presents a new approach for offshore risk analysis that is capable of dealing with linguistic probabilities in Bayesian networks （ BNs）. In this paper, linguistic probabilities are used to describe occurrence likelihood of hazardous events that may cause possible accidents in offshore operations. In order to use fuzzy information, an f-weighted valuation function is proposed to transform linguistic j.dgements into crisp probability distributions which can be easily put into a BN to model causal relationships among risk factors. The use of linguistic variables makes it easier for human experts to express their knowledge, and the transformation of linguistic j.dgements into crisp probabilities can significantly save the cost of computation, modifying and maintaining a BN model. The flexibility of the method allows for multiple forms of information to be used to quantify model relationships, including formally assessed expert opinion when quantitative data are lacking, or when only qualitative or vague statements can be made. The model is a modular representation of uncertain knowledge caused due to randomness, vagueness and ignorance. This makes the risk analysis of offshore engineering systems more functional and easier in many assessment contexts. Specifically, the proposed f-weighted valuation function takes into account not only the dominating values, but also the a-level values that are ignored by conventional valuation methods. A case study of the collision risk between a Floating Production, Storage and Off-loading （FPSO） unit and the anthorised vessels due to human elements during operation is used to illustrate the application of the proposed model.

关键词： Risk analysis fiweighted valuation function Bayesian networks fuzzy number linguistic probability off-shore engineering systems

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The HIF-1α/PlOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

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Bone Research 2024年第2期12卷 289-301页

作者： Heeseog Kang Amy l.Strong Yuxiao Sun lei Guo Conan j.an Alec C.Bancroft j. Hae Choi Chase A.Pagani Aysel A.Fernandes Michael Woodard j.hoon lee Sowmya Ramesh Aaron W.j.mes David Hudson Kevin N.Dalby lin Xu Robert j.Tower Benj.min levi Center for Organogenesis Regeneration and TraumaDepartment of SurgeryUniversity of Texas SouthwesternDallasTX 75390USA Section of Plastic Surgery Department of SurgeryUniversity of MichiganAnn ArborMI 48109USA Quantitative Biomedical Research Center Peter O’Donnell Jr.School of Public HealthUniversity of Texas SouthwesternDallasTX 75390USA Department of Orthopedics and Sports Medicine University of WashingtonSeattleWA 98195USA Division of Chemical Biology and Medicinal Chemistry College of PharmacyUniversity of Texas at AustinAustinTX 78712USA Department of Pathology Johns Hopkins UniversityBaltimoreMD 21218USA

While hypoxic signaling has been shown to play a role in many cellular processes,its role in metabolism-linked extracellular matrix(ECM)organization and downstream processes of cell fate after musculoskeletal inj.ry remains to be ***(HO)is a debilitating condition where abnormal bone formation occurs within extra-skeletal *** andhypoxia-inducible factor 1α(HIF-1α)activation have been shown to promote ***,the underlying molecular mechanisms bywhich the HIF-1αpathway in mesenchymal progenitor cells(MPCs)contributes to pathologic bone formation remain to ***,we used a proven mouse inj.ry-induced HO model to investigate the role of HIF-1αon aberrant cell ***-cell RNA sequencing(scRNA-seq)and spatial transcriptomics analyses of the HO site,we found that collagen ECM organizationis the most highly up-regulated biological process in *** mesenchymal cell-specific deletion of Hif1α(Hoxa11-CreER^(T2);Hif1a^(fl/fl))significantly mitigated HO in ***-seq analysis of these Hoxa11-CreER^(T2);Hif1a^(fl/fl)mice identified the PlOD2/lOXpathway for collagen cross-linking as downstream of the HIF-1αregulation of ***,our scRNA-seq data and mechanisticstudies further uncovered that glucose metabolism in MPCs is most highly impacted by HIF-1α*** a translational aspect,a pan-lOX inhibitor significantly decreased HO.A newly screened compound revealed that the inhibition of PlOD2 activity in MPCssignificantly decreased osteogenic differentiation and glycolytic *** suggests that the HIF-1α/PlOD2/lOX axis linked tometabolism regulates HO-forming MPC *** results suggest that the HIF-1α/PlOD2/lOX pathway represents a promisingstrategy to mitigate HO formation.

关键词： metabolism skeletal aberrant

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Clinical and Demographic Profile of Women with Uterine Fibroids living in Puerto Rico

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Open j.urnal of Obstetrics and Gynecology 2024年第9期14卷 1347-1362页

作者： Edwin Y. Soto-Velázquez Alexander j. j.ramillo-Cañas Shania N. Aponte-Paris Gabriela V. Martínez-Marrero Irazu S. Guinan Gabrielle A. Rivera-Maldonado Alexandra Novas Pedro l. Cruz-Rosa Idhaliz Flores-Caldera Maricarmen Colón-Diaz Department of Physiology and Pathology San Juan Bautista School of Medicine Caguas Puerto Rico United States Ponce Research Institute Ponce Health Sciences University Ponce Puerto Rico United States

Introduction: Uterine leiomyomas, or fibroids, are prevalent benign tumors affecting up to 70% of reproductive-age women in the United States, significantly impacting productivity and quality of life. Despite their commonality, the epidemiology and clinical patterns of leiomyomas in Puerto Rico remain inadequately researched. Methods: This study conducted a secondary data analysis using clinical, menstrual cycle characteristics, and demographic data from self-administered questionnaires of women undergoing diagnostic laparoscopy for endometriosis in Puerto Rico. Chi-square tests and t-tests analyzed categorical and continuous variables, respectively (p Results: Among 1,610 endometriosis cases, 312 included uterine fibroids. Prevalence estimates were 10.3% (40 years). Primiparous women averaged 22.14 years, with 40.71% having 2 - 3 pregnancies and 26.28% experiencing miscarriages. Symptoms included infertility (29.5%), dyspareunia (40.7%), severe pain (50%), and dysmenorrhea (75.6%). Comorbidities included ovarian cysts (52.2%) and abnormal uterine bleeding (37.8%). Conclusions: Advanced age, parity, and comorbidities like diabetes and hypertension were prevalent in our cohort. Understanding the epidemiological profile of women living in Puerto Rico with uterine fibroids is crucial for improving diagnostic awareness and enhancing patient care.

关键词： Uterine Fibroids Puerto Rico Epidemiology Dysmenorrhea Abnormal Uterine Bleeding

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初夏东北冷涡指数的建立与分析(1961-2010)

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全球变化数据学报（中英文） 2024年第1期8卷 104-109,V0104-V0109页

作者：何丽烨马宁郭军天津市气候中心天津300074

东北冷涡是东亚中高纬度地区的重要天气系统,其频繁活动能够导致明显的气温和降水异常,具有显著的“气候效应”。使用水平分辨率为2.5°×2.5°、时间分辨率为逐日的NCEP/NCAR(美国国家环境预报中心和国家大气研究中心)再分析资料,研究... 详细信息

东北冷涡是东亚中高纬度地区的重要天气系统,其频繁活动能够导致明显的气温和降水异常,具有显著的“气候效应”。使用水平分辨率为2.5°×2.5°、时间分辨率为逐日的NCEP/NCAR(美国国家环境预报中心和国家大气研究中心)再分析资料,研究时段取1961–2010年。根据东北冷涡天气学定义,将符合下述条件的天气系统定义为一次冷涡天气过程:(1)在500hPa等压面上至少能分析出一根闭合等高线,并有冷中心或明显冷槽配合的低压环流系统;(2)冷涡中心出现在(35°N–60°N,115°E–145°E)范围内;(3)冷涡在上述地区的生命史为3天或3天以上。考虑海河流域的地理位置,根据逐年东北冷涡低压中心在西涡范围(115°E–125°E)达到的最南位置,界定对初夏(6月,下同)海河流域降水有显著影响的东北冷涡活动关键区域(38°N–48°N,115°E–125°E),统计出冷涡中心频次标准化值,形成初夏东北冷涡指数数据集(1961–2010)。数据集包括:(1)初夏标准化东北冷涡活动指数;(2)逐年初夏东北冷涡500 hPa位势高度低压中心在115°E–125°E区域的最南位置。该数据集存储为1个Excel文件(.xlsx格式),数据量约12.5 KB。

关键词：东北冷涡初夏降水海河流域气候效应

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Adding Value to Crop Production Systems by Integrating Forage Cover Crop Grazing

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American j.urnal of Plant Sciences 2024年第3期15卷 180-192页

作者： Robert B. Mitchell Daren D. Redfearn Kenneth P. Vogel Terry j. Klopfenstein Galen Erickson P. Stephen Baenziger Bruce E. Anderson Mary E. Drewnoski j.y Parsons Steven D. Masterson Marty R. Schmer Virginia l. j.n USDA-ARS Wheat Sorghum and Forage Research Unit University of Nebraska-Lincoln Lincoln NE USA Department of Agronomy and Horticulture University of Nebraska-Lincoln Lincoln NE USA Department of Animal Science University of Nebraska-Lincoln Lincoln NE USA Department of Agricultural Economics University of Nebraska-Lincoln Lincoln NE USA USDA-ARS Agroecosystem Management Research Unit University of Nebraska-Lincoln Lincoln NE USA

In addition to their value as cereal grains, wheat (Triticum aestivum l.) and triticale (× Triticosecale Wittmack) are important cool-season annual forages and cover crops. Yearling steer (Bos taurus) performance was compared in the spring following autumn establishment as for age cover crops after soybean [Glycine max (l.) Merr.] grain harvest. Replicated pastures (0.4 ha) were no-till seeded in three consecutive years into soybean stubble in autumn, fertilized, and grazed the following spring near Ithaca, NE, USA. Each pasture (n = 3) was continuously stocked in spring with four yearling steers (380 ± 38 kg) for 17, 32, and 28 d in 2005, 2006, and 2007, respectively. In 2005, average daily gain (ADG) for steers grazing triticale exceeded the ADG for wheat by 0.31 kghd-1d-1. In 2006, wheat ADG exceeded that for triticale by 0.12 kghd-1d-1. In 2007, steers grazing wheat lost weight, while steers grazing triticale gained 0.20 kghd-1d-1. Based on the 3-year average animal gains valued at $1.32 kg-1, mean net return ($ ha-1 yr-1) was $62.15 for triticale and $22.55 for wheat. Since these grazed cover crops provide ecosystem services in addition to forage, grazing could be viewed as a mechanism for recovering costs and adds additional value to the system. Based on this 3-year grazing trial, triticale was superior to wheat and likely will provide the most stable beef yearling performance across years with variable weather for the western Cornbelt USA.

关键词： Cover crops Soybean Triticale Wheat

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Ab initio valence-space in-medium similarity renormalization group calculations for neutron-rich P,Cl,and K isotopes

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Chinese Physics C 2024年第7期48卷 181-190页

作者：谢萌冉沈留媛李健国李红蕙袁琪左维 Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China

Neutron-rich P,Cl,and K isotopes,particularly those with neutron numbers of approximately N=28,have attracted extensive experimental and theoretical *** utilize the ab initio valence-space in-medium similarity renormalization group approach,based on chiral nucleon-nucleon and three-nucleon forces,to investigate the exotic properties of these *** calculations of the low-lying spectra are performed.A key finding is the level inversion between 3/2_(1)^(+)and 1/2_(1)^(+)states in odd-A isotopes,attributed to the inversion ofπ0xod_(3/2) andπls_(1/2) single-particle *** ab initio calculations,which incorporate the three-nucleon forces,correlate closely with existing experimental *** calculations of effective proton single-particle energies provide deeper insights into the shell evolution for Z=14 and 16 *** results indicate that the three-body force plays important roles in the shell evolution for Z=14 and 16 sub-shells with neutron numbers ranging from 20 to ***,systematic ab initio calculations are conducted for the low-lying spectra of odd-odd *** results correspond with experimental data and provide new insights for future research into these isotopes up to and beyond the drip line.

关键词： ab initio calculations shell evolution low-lying spectra

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Effects of torpedo blasting on rockburst prevention during deep coal seam mining in the Upper Silesian Coal Basin

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j.urnal of Rock Mechanics and Geotechnical Engineering 2017年第4期9卷 694-701页

作者： l. Woj.ecki P. Konicek j. Schreiber Polish Mining Group Powstanców 30 Katowice 40-039 Poland Department of Geomechanics and Mining Research Institute of Geonics Czech Academy of Sciences Studentska 1768 Ostrava-Poruba 708 00 Czech Republic

In the Upper Silesian Coal Basin(USCB),coal seams are exploited under progressively more difficult geological and mining conditions(greater depth,higher horizontal stress,more frequent occurrence of competent rock layers,etc.).Mining depth,dislocations and mining remnants in coal seams are the most important factors responsible for the occurrence of rockburst *** mining next to the mining edges of neighbouring coal seams is particularly *** levels of rockburst hazards are minimised via the use of rockburst prevention *** active prevention method is torpedo blasting in roof *** blastings are performed in order to decrease local stress concentrations in rock masses and to fracture the roof rocks to prevent or minimise the impact of high-energy tremors on *** estimation of the effectiveness of torpedo blasting is particularly important when mining is under difficult geological and mining *** blasting is the main form of active rockburst prevention in the assigned colliery in the Polish part of the *** effectiveness of blasting can be estimated using the seismic effect method,in which the seismic monitoring data and the mass of explosives are taken into *** seismic effect method was developed in the Czech Republic and is always being used in collieries in the Czech part of the coal ***,this method has been widely adopted for our selected colliery in the Polish part of the coal *** effectiveness of torpedo blastings in the faces and galleries of the assigned longwall in coal seam 506 has been *** results show that the effectiveness of torpedo blastings for this longwall was significant in light of the seismic effect method,which corresponds to the in situ *** seismic effect method is regularly applied to estimating the blasting effectiveness in the selected colliery.

关键词： Rockburst prevention Torpedo blasting Seismic effect Upper Silesian Coal Basin(USCB)

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Pressure-dependent phase transition of 2D layered silicon telluride(Si2le3)and manganese intercalated silicon telluride

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Nano Research 2019年第9期12卷 2373-2377页

作者： Virginia l. j.hnson Auddy Anilao Kristie j. Koski Department of Chemistry University of CaliforniaDavisDavisCA 95616USA

Two-dimensional(2D)layered silicon telluride(SizTes)nanocrystals were compressed to 12 GPa using diamond anvil cell *** measurements show a color change from transparent red to opaque black indicating a semiconductor-to-metal phase *** scattering was used to observe the stiffening of the crystal lattice and subsequent phase behavior.A possible phase transition was *** 9.5±0.5 GPa evidenced by the disappearance of the Atg stretching *** was intercalated with elemental manganese to^1 at.%.Intercalation lowers the pressure of the proposed phase transition to 7.5±1 *** modes show both phonon stiffening and phonon softening,suggesting negative linear *** results provide fundamental insight into the high-pressure optical phonon behavior of silicon telluride and illuminate how a specific electron-donating intercalant can chemically alter pressure-dependent optical phonon behavior.

关键词： silicon telluride Si2Te3 high pressure diamond anvil cell two-dimensional(2D)layered material

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Preparation of neodymium-doped yttrium aluminum garnet powders and fibers

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j.urnal of Rare Earths 2008年第5期26卷 670-673页

作者： R. lópez j. Zárate E. A. Aguilar j. Muoz-Saldaa Instituto de Investigaciones Metalurgicas UMSNH Morelia Centro de Investigación y de Estudios Avanzados del IPN Unidad Queretaro

Using nitrate precursors, a novel spray-drying assisted citrate gel process for the preparation of neodymium-doped yttrium alumi- num garnet （YAG） phase was developed. Synthesis of single-phase polycrystalline YAG was achieved at temperatures as low as 800 ℃ using the spray-drying methodology whilst conventional approaches currently available require 1000 ℃. Initially, a solution was prepared by mixing aluminum and yttrium nitrates, citric acid, etilenglycol and neodymium oxide. This solution was dried by pulverization （spray dryer） to obtain aggregated precursor powders of the compound. These aggregates were calcined at 800, 850 and 900 ℃ to determine the phase evolution from amorphous to crystalline by X-ray diffraction （XRD）. The morphology of aggregates was characterized by scanning electron microscopy （SEM） and transmission electron microscopy （TEM）. Moreover, through XRD it was determined that the crystallization of YAG phase started at about 800 ℃ without any intermediate phases. The powders were composed of spherical aggregates with an average diameter of 1 um. From these powders, ceramic fibers with additions of 2at.% and 5at.% Nd, were extracted from the melt with diameters ranging from 30 um to 50 um.

关键词： spray-drying melt extraction fibers yttrium aluminum garnet rare earths

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Impact of payment source, referral site, and place of residence on outcomes after allogeneic transplantation in Mexico

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World j.urnal of Transplantation 2024年第2期14卷 76-87页

作者： Andrés Gómez-De león Yesica A lópez-Mora Valeria García-Zárate Ana Varela-Constantino Sergio U Villegas-De leon Xitlaly j.González-leal Raúl del Toro-Mij.res Anna C Rodríguez-Zúñiga j.an F Barrios-Ruiz Victor Mingura-ledezma Perla R Colunga-Pedraza Olga G Cantú-Rodríguez César H Gutiérrez-Aguirre luz Tarín-Arzaga Elías E González-lópez David Gómez-Almaguer Hematology Service Universidad Autónoma de Nuevo LeónFacultad de Medicina y Hospital Universitario Dr.JoséEleuterio GonzálezMonterrey 64460Nuevo LeónMexico Hemato-logy Service Clínica Gómez AlmaguerMonterrey 64710Nuevo LeónMexico Hematology Service Instituto Tecnológico de Estudios Superiores de MonterreyTec SaludEscuela de Medicina Ignacio SantosMonterrey 64710Nuevo LeónMexico

BACKGROUND The impact of social determinants of health in allogeneic transplant recipients in low-and middle-income countries is poorly *** observational study analyzes the impact of place of residence,referring institution,and transplant cost coverage(out-of-pocket vs government-funded vs private insurance)on outcomes after allogeneic hematopoietic stem cell transplantation(alloHSCT)in two of Mexico's largest public and private *** To evaluate the impact of social determinants of health and their relationship with outcomes among allogeneic transplant recipients in *** In this retrospective cohort study,we included adolescents and adults≥16 years who received a matched sibling or haploidentical transplant from *** were selected without regard to their diagnosis and were sourced from both a private clinic and a public University Hospital in *** payment groups were compared:Out-of-pocket(OOP),private insurance,and a federal Universal healthcare program“Seguro Popular”.Outcomes were compared between referred and institution-diagnosed patients,and between residents of Nuevo leon and *** outcomes included overall survival(OS),categorized by residence,referral,and payment *** outcomes encompassed early mortality,event-free-survival,graft-versus-host-relapse-free survival,and non-relapse-mortality(NRM).Statistical analyses employed appropriate tests,Kaplan-Meier method,and Cox proportional hazard regression *** software included SPSS and R with tidycmprsk *** Our primary outcome was overall *** included 287 patients,n=164 who lived out of state(57.1%),and n=129 referred from another institution(44.9%).The most frequent payment source was OOP(n=139,48.4%),followed by private insurance(n=75,26.1%)and universal coverage(n=73,25.4%).No differences in OS,event-free-survival,NRM,or graft-versus-host-relapse-free survival were observed for patients dia

关键词： Hematopoietic cell transplant Social determinants of health Geography Haploidentical Out-of-pocket Financial toxicity Survival Health services and outcomes Hematopoietic malignancy Aplastic anemia

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