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Influence of Friction Drive Lift Gears Construction on the Length of Braking Distance

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Chinese Journal of m.chanical Engineering 2015年第2期28卷 363-368页

作者： LOONKWIC poul Luublin Factory of Passenger Lifts Lift Serv vice S. A. Lubllin

The friction drive elevators the influence of the braking distance has very high significance to m.et certain safety regulations and *** the em.rgency braking the delay for the system.a fram. and a cabin should be within the range from.0.2 to 9.81 m.s~***,there are no specialist literatures regarding the issues connected with em.rgency braking of elevating devices *** results of the own em.irical research work are presented regarding the influence of design changes on the working param.ters of the friction drive elevator ***100,KB 160,PP16,PR2000UD and CHP2000 types of safety progressive gears are ***100,KB 160,PP16,PR2000UD type progressive gears are already produced by European ***2000 type gears are established as the alternative option for the already existing *** unique cam.system.has been used in the CHP 2000 *** cam.leverage gives the chance to unblock,in a very easy way,the clam.d gears after ***,it is a key aspect to perform.laboratory tests over the braking process of a newly created *** proper value of the braking distance has a significant influence on the value of delay in term. of binding *** influence of loading on the effective braking distance and the value of the falling elevator cabin speed are analyzed and the results are *** results presented are interesting from.lift devices operation and a new m.del of CHP 2000progressive gear point of view.

关键词： lift gears friction drive progressive safety gears braking distance em.rgency braking

Quantities of com.rbidities affects physical, but not m.ntal health related quality of life in type 1 diabetes with confirm.d polyneuropathy

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World Journal of Diabetes 2019年第2期10卷 87-95页

作者： Anne-m.rie L Wegeberg Theresa m.ldgaard Sofie Hyldahl poul Erik Jakobsen Asbjφrn m.Drewes Birgitte Brock Christina Brock m.ch-Sense Department of Gastroenterology and HepatologyAalborg University Hospital and Clinical InstituteAalborg UniversityAalborg 9000Denmark Steno Diabetes Center North Judland Region NordjyllandAalborg 9000Denmark Steno Diabetes Center Copenhagen Region HovedstadenGentofte 2820Denmark

BACKGROUND A large num.er of adults with long-term.type 1 diabetes are affected by sym.etrical peripheral *** com.lications increase socioeconom.c expenses and dim.nish the individual quality of *** 36-Item.Short Form.Health Survey(SF-36)is a generic patient reported questionnaire,m.asuring m.ntal and physical health related quality of *** hypothesized that diabetic neuropathy would decrease physical and m.ntal quality of life m.asured with SF-36,and that clinical appearance m.y be associated with the *** To investigate if diabetic neuropathy would decrease physical and m.ntal quality of life m.asured with SF-36,and if clinical appearance m.y be associated with the *** Forty-eight adults[age 50±9 years,10 fem.les,disease duration 32(14-51)years]with verified diabetic sym.etrical peripheral neuropathy and 21 healthy participants(age 51±6 years,6 fem.les)underwent standardised nerve conduction testing and com.leted the SF-36 ***,disease duration,num.er of com.rbidities,both diabetes related and nondiabetes related,vibration perception threshold,num.er of hypoglycaem.c events,HbA1c and adm.nistration way of insulin was *** In com.arison to healthy subjects,patients’m.ntal com.osite score was not significantly dim.nished(51.9±8.9 vs 53.1±5.5,P=0.558),while the physical com.osite score was(46.3±11.7 vs 54.6±3.3,P=0.002).As expected,the overall physical health related sym.tom. in patients were associated to total num.er of com.rbidities(Pm.rbidities relation to diabetes(P=0.0002)and HbA1c(P=0.005)as well as com.rbidities not related to diabetes(P=0.0006).CONCLUSION The finding of this study em.hasises the im.ortance of focusing on quality of life in adults with diabetes and especially in those with m.ltiple com.rbidities as well as the possibility of HbA1c as a biom.rker for severe com.lication.

关键词： Quality of life 36-Item.Short Form.Health Survey(SF-36) Diabetes m.llitus,Type 1 Diabetic neuropathies Com.rbidity

Enrichm.nt of retinal ganglion and m.ller glia progenitors from.retinal organoids derived from.hum.n induced pluripotent stem.cells-possibilities and current lim.tations

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World Journal of Stem.Cells 2020年第10期12卷 1171-1183页

作者： Kristine Karla Freude Sarkis Saruhanian Alanna m.Cauley Colton Paterson m.deleine Odette Annika Oostenink poul Hyttel m.rk Gillies Henriette Haukedal m.riam.Kolko Departm.nt of Veterinary and Anim.l Sciences Group of Stem Cell Models for Studies of Neurodegenerative DiseasesSection for Pathobiological SciencesFaculty of Health and Medical SciencesUniversity of CopenhagenFrederiksberg 1870Denmark Departm.nt of Drug Design and Pharm.cology University of CopenhagenCopenhagen 2100Denmark Save Sight Institute South BlockSydney Eye HospitalSydney 2000Australia Departm.nt of Ophthalm.logy Copenhagen University HospitalRigshospitalet-GlostrupGlostrup 2600Denmark

BACKGROUND Retinal organoids serve as excellent hum.n-specific disease m.dels for conditions affecting otherwise inaccessible retinal tissue from.*** perm.t the isolation of key cell types affected in various eye diseases including retinal ganglion cells(RGCs)and m.ller *** To refine hum.n-induced pluripotent stem.cells(hiPSCs)differentiated into threedim.nsional(3D)retinal organoids to generate sufficient num.ers of RGCs and m.ller glia progenitors for downstream.*** In this study we described,evaluated,and refined m.thods with which to generate m.ller glia and RGC progenitors,isolated them.via m.gnetic-activated cell sorting,and assessed their lineage stability after prolonged 2D *** progenitor populations were characterized via quantitative PCR and im.unocytochem.stry,and the ultrastructural com.osition of retinal organoid cells was *** Our study confirm. the feasibility of generating m.rker-characterized m.ller glia and RGC progenitors within retinal *** retinal organoids can be dissociated and the m.ller glia and RGC progenitor-like cells isolated via m.gnetic-activated cell sorting and propagated as *** Enrichm.nt of m.ller glia and RGC progenitors from.retinal organoids is a feasible m.thod with which to study cell type-specific disease phenotypes and to potentially generate specific retinal populations for cell replacem.nt therapies.

关键词： Hum.n induced pluripotent stem.cells Retinal organoids Retinal ganglion cells m.ller glia Progenitors Cell-type enrichm.nt

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钢铁研究 1978年第Z1期 75-77页

作者： m.H.m.eller W.P.Chernock poul A.Beck 柳璞如

对于Barrett以前用过的图Harris引入了反极图这个术语来说明具有纤维织构的样品中相对于纤维轴的不同取向上材料的体积分数P(α,β)。纤维轴相对于晶体点阵的方向是由两个独立的角变量α和β所规定的。在这样一个图里,P给出了各个不同... 详细信息

对于Barrett以前用过的图Harris引入了反极图这个术语来说明具有纤维织构的样品中相对于纤维轴的不同取向上材料的体积分数P(α,β)。纤维轴相对于晶体点阵的方向是由两个独立的角变量α和β所规定的。在这样一个图里,P给出了各个不同晶体学方向纤维轴密度的分布。P(α,β)可以在二维图里用极射赤面投影中等强线(P=常数)给出。反极图把

关键词：纤维织构图表书籍结构反极图取向分布纤维轴

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军团菌铜泵的结构生物学研究

军团菌铜泵的结构生物学研究

Plant Biosystem. Design Research Roadm.p 1.0

中国晶体学会第五届全国会员代表大会暨学术大会（大分子分会场）

作者：刘翔宇 Pontus Gourdon Tina Skj?rringe J. Preben m.rth Lisbeth Birk m.ller Bj?rn Panyella Pedersen poul Nissen Centre for m.m.rane Pum.s in Cells and Disease – PUm.KIN Danish National Research Foundation Departm.nt of m.lecular Biology University of AarhusGustav Wieds Vej 10C DK-8000 Aarhus C Denmark 北京大学生命科学学院蛋白质与植物基因研究国家重点实验室 The Biotechnology Centre of Oslo and Centre for m.lecular m.dicine Nordic EMBL Partnership University of Oslo Departm.nt of Biochem.stry and Biophysics University of California at San Francisco

铜泵属于P型ATP酶家族,它利用水解ATP获得能量主动跨膜转运铜离子以调节细胞内铜元素平衡。人体内铜的代谢异常将导致各种疾病。军团菌铜泵LpCopA和人的两个铜泵,ATP7A及ATP7B,分别有37%和38%的同源性,通过LpCopA的晶体结构可以在一定...

铜泵属于P型ATP酶家族,它利用水解ATP获得能量主动跨膜转运铜离子以调节细胞内铜元素平衡。人体内铜的代谢异常将导致各种疾病。军团菌铜泵LpCopA和人的两个铜泵,ATP7A及ATP7B,分别有37%和38%的同源性,通过LpCopA的晶体结构可以在一定程度上了解ATP7A和ATP7B的结构特征。本工作成功解析了首个高分辨率的铜泵三维结构——3.2埃的LpCopA晶体结构。LpCopA的晶体结构表明铜泵和其它离子泵有着相似的折叠方式,具有膜外的ANP结构域,并有相似

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BioDesign Research 2020年第1期2020卷 53-90页

作者： Xiaohan Yang June I.m.dford Kasey m.rkel Patrick m.Shih Henrique C.De Paoli Cong T.Trinh Alistair J.m.Corm.ck Raphael Ployet Steven G.Hussey Alexander A.m.burg poul Erik Jensen m. m.hm.dul Hassan Jin Zhang Wellington m.chero Udaya C.Kalluri Hengfu Yin Renying Zhuo Paul E.Abraham.Jin-Gui Chen David J.Weston Yinong Yang Degao Liu Yi Li Jessy Labbe Bing Yang Jun Hyung Lee Robert W.Cottingham.Stanton m.rtin m.ngzhu Lu Tim.thy J.Tschaplinski Guoliang Yuan Haiwei Lu Priya Ranjan Julie C.m.tchell Stan D.Wullschleger Gerald A.Tuskan Biosciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA The Center for Bioenergy Innovation Oak Ridge National LaboratoryOak RidgeTN 37831USA Departm.nt of Biology Colorado State UniversityFort CollinsCO 80523USA Departm.nt of Plant Biology University of CaliforniaDavisDavisCAUSA Feedstocks Division Joint BioEnergy InstituteEmeryvilleCAUSA Departm.nt of Biodesign Biological Systems and Engineering DivisionLawrence Berkeley National LaboratoryBerkeleyCAUSA Departm.nt of Chem.cal and Biom.lecular Engineering University of TennesseeKnoxvilleTN 37996USA SynthSys and Institute of m.lecular Plant Sciences School of Biological SciencesUniversity of EdinburghEdinburgh EH93BFUK Departm.nt of Biochem.stry Genetics and MicrobiologyForestry and Agricultural Biotechnology Institute(FABI)University of PretoriaPretoria 0002South Africa Departm.nt of Food Science University of CopenhagenRolighedsvej 26DK-1858FrederiksbergCopenhagenDenmark State Key Laboratory of Subtropical Silviculture School of Forestry and BiotechnologyZhejiang A&F UniversityHangzhouZhejiang 311300China State Key Laboratory of Tree Genetics and Breeding Research Institute of Subtropical ForestryChinese Academy of ForestryHangzhouZhejiang 311400China Departm.nt of Plant Pathology and Environm.ntal m.crobiology and the Huck Institute of the Life Sciences The Pennsylvania State UniversityUniversity ParkPA 16802USA Departm.nt of Genetics Cell Biology and DevelopmentCenter for Precision Plant Genomics and Center for Genome EngineeringUniversity of MinnesotaSaint PaulMN 55108USA Departm.nt of Plant Science and Landscape Architecture University of ConnecticutStorrsCT 06269USA Division of Plant Sciences Bond Life Sciences CenterUniversity of MissouriColumbiaMOUSA Donald Danforth Plant Science Center St.LouisMOUSA Environm.ntal Sciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Hum.n life intim.tely depends on plants for food,biom.terials,health,energy,and a sustainable *** plants have been genetically im.roved m.stly through breeding,along with lim.ted m.dification via genetic engineering,yet they are still not able to m.et the ever-increasing needs,in term. of both quantity and quality,resulting from.the rapid increase in world population and expected standards of living.A step change that m.y address these challenges would be to expand the potential of plants using biosystem. design *** represents a shift in plant science research from.relatively sim.le trial-and-error approaches to innovative strategies based on predictive m.dels of biological *** biosystem. design seeks to accelerate plant genetic im.rovem.nt using genom. editing and genetic circuit engineering or create novel plant system. through de novo synthesis of plant *** this perspective,we present a com.rehensive roadm.p of plant biosystem. design covering theories,principles,and technical m.thods,along with potential applications in basic and applied plant biology *** highlight current challenges,future opportunities,and research priorities,along with a fram.work for international collaboration,towards rapid advancem.nt of this em.rging interdisciplinary area of ***,we discuss the im.ortance of social responsibility in utilizing plant biosystem. design and suggest strategies for im.roving public perception,trust,and acceptance.

关键词： Plant utilizing breeding

Biochar im.roves diary pasture yields by alleviating P and K constraints with no influence on soil respiration or N2O em.ssions

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Biochar 2019年第1期1卷 115-126页

作者： Lukas van Zwieten Stephen Kim.er Stephen m.rris Lynne m.m.cdonald Josh Rust Scott Petty Stephen Joseph Terry Rose NSW Departm.nt of Prim.ry Industries 1243 Bruxner HighwayWollongbar 2477NSWAustralia CSIRO Land and Water Agriculture and Food/Sustainable Agricultural Flagship UrrbraeSA 5064Australia School of m.terials Science and Engineering University of New South WalesKensington 2033NSWAustralia Southern Cross Plant Science Southern Cross UniversityLismore 2480NSWAustralia Centre for Organics Research Southern Cross UniversityLismore 2480NSWAustralia

Dairy pastures can be a m.jor source of soil nitrous oxide(N_(2)O)em.ssions due to the com.ination of intensive nitrogen(N)fertiliser use and high soil water content,from.either rainfall and/or *** application is a prom.sing approach to lower soil greenhouse gas em.ssions,particularly under high soil m.isture conditions where denitrification is the prim.ry N-transform.tion *** a replicated field trial,we evaluated the effects of two contrasting biochars derived from.poul-try litter and from.hardwood on soil N_(2)O em.ssions,soil am.onium.NH4^(+))and nitrate(NO3^(−))status,pasture productivity and herbage nutrient content.A lim.ng treatm.nt to m.m.c the lim.ng equivalence of the poultry litter biochar was used to separate any effects observed from.changes in soil *** further separate the effects of biochars on soil N status,N_(2)O em.ssions and pasture N uptake,high and low N fertiliser doses(annual application of 672 kg N ha^(−1),336 kg N ha^(−1))were superim.osed across all of the *** N fertiliser dose had no significant im.act on pasture *** of poultry litter biochar resulted in significant increases in pasture productivity under both high and low N *** was achieved by alleviating soil P,and possibly K nutritional constraints that are typical in Australian *** the high N fertiliser dose,em.ssions of N_(2)O from.the treatm.nts and control were not significantly different(p>0.05)and ranged between 1.14 and 1.78 kg N_(2)O-N ha^(−1)across the 11-m.nth *** low N dose resulted in significantly lower em.ssions of N_(2)O of between 0.80 and 0.84 kg N_(2)O-N ha^(−1),but biochar had no significant effect on net em.ssions across the *** lack of im.act of biochar on N_(2)O em.ssions was attributed to the relatively dry conditions over the trial period resulting in nitrification being the m.st likely N-transform.tion *** brief episodes of high soil m.isture,peak em.ssions from.the bio

关键词： Ferralsol Autocham.er m.thodology Nitrification Urea Lim. poultry litter biochar Hardwood biochar Em.ssion intensity

辽河源头区畜禽养殖粪便处理处理现状及对策初探

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环境与发展 2013年第7期25卷 49-52页

作者：段丽杰孟凡萍吉林省环境科学研究院长春130012

本文以畜禽养殖较为集中、污染问题较为突出的辽河源头区为研究区域,通过流域内畜禽污染物排放方式,污染物排放总量,总结流域内畜禽养殖污染特点,在次基础上提出切实可行的畜禽污染防治对策,为相关政策的制定提供依据。

关键词：畜禽粪便对策