检索结果-南通市图书馆

Plastic multilayered closure versus orthopedic surgeon closure after spinal instrumentation in pediatric neuromuscular scoliosis

引用

World Journal of Pediatric Surgery 2023年第1期6卷 30-35页

作者： Ekene U Ezeokoli poornima l tamma Neritan Borici Ifeoma Inneh Edward P Buchanan Brian G Smith Department of Orthopedic Surgery Texas Children's HospitalHoustonTexasUSA Baylor College of Medicine HoustonTexasUSA Department of Plastic Surgery Texas Children's HospitalHoustonTexasUSA Department of Orthopedic Surgery Baylor College of MedicineHoustonTexasUSA

Objective To compare wound complication rates between orthopedic closure(OC)and plastic multilayered closure(PMC)in patients undergoing primary posterior spinal fusion for neuromuscular scoliosis(NMS).We hypothesize that multilayered closure will be associated with better postoperative *** We collected data on pediatric patients diagnosed with NMS who underwent first time spinal instrumentation between 1 January 2018 and 31 May *** demographics,length of surgery,spinal levels fused and operative variables,wound complication rate,treatments,and need for wound washout were reviewed in depth and *** In total,86 patients were reviewed:46 with OC and 40 with *** was a significant increase in operating room(OR)time with PMC compared with OC(6.7±1.2 vs 7.3±1.3,p=0.016).There was no difference in complication rate,mean postoperative day of complication or unplanned return to the OR for OC and PMC,*** was a slightly significant increase in the number of patients going home with a drain in the PMC cohort compared with the OC cohort(2.1%vs 15%,p=0.046).Conclusions PMC demonstrated longer OR times than OC and did not demonstrate a statistically significant reduction in wound complications or unplanned returns to the ***,other studies have demonstrated statistical and clinical significance with these *** programs should review internal patient volumes and outcomes for spinal fusion in NMS patients and consider if PMC after spinal fusions in pediatric patients with NMS or other scoliosis subtypes is an appropriate option in their institution to minimize postoperative wound complications.

关键词： wound pediatric closure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inter-annual and seasonal variations in hydrological parameters and its implications on chlorophyll a distribution along the southwest coast of Bay of Bengal

引用

Acta Oceanologica Sinica 2015年第6期34卷 94-100页

作者： Shanthi R. poornima D. Raja K. Sarangi R.K. Saravanakumar A. Thangaradjou T. Centre of Advanced Study in Marine Biology Faculty of Marine Sciences Annamalai University Marine Geo and Planetary Sciences Group Space Application Centre (ISRO)

Seasonal and inter-annual variability of hydrological parameters and its impact on chlorophyll distribution was studied from January 2009 to December 2011 at four coastal stations along the southwest Bay of Bengal. Statistical analysis （principal component analysis （PCA）, two-way analysis of variance （ANOVA） and correlation analysis） showed the significant impact of hydrological parameters on chlorophyll distribution in the study area. The ranges of different parameters recorded were 23.8-33.8℃ （SST）, 4.00-36.00 （salinity）, 7.0-9.2 （pH）, 4.41-8.32 mg/l （dissolved oxygen）, 0.04-2.45 μmol/l （nitrite）, 0.33-16.10 μmol/l （nitrate）, 0.02-2.51 μmol/l （ammonia）, 0.04-3.32 μmol/l （inorganic phosphate）, 10.09-85.28 μmol/l （reactive silicate） and 0.04-13.8 μg/l （chlorophyll）. PCA analysis carried out for different seasons found variations in the relationship between physico-chemical parameters and chlorophyll in which nitrate and chlorophyll were positively loaded at PC1 （principal component 1） during spring inter-monsoon and at PC2 （principal component 2） during other seasons. likewise correlation analysis also showed significant positive relationship between chlorophyll and nutrients especially with nitrate （~0.734）. Distribution of hydrobiological parameters between stations and distances was significantly varying as evidenced from the ANOVA results. The study found that the spatial and temporal distribution of chlorophyll was highly dependent on the availability of nutrients especially, nitrate in the southwest Bay of Bengal coastal waters.

关键词： chlorophyll nutrients PCA nitrate correlation analysis Bay of Bengal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Reversal of doxorubicin resistance in lung cancer cells by neferine is explained by nuclear factor erythroid-derived 2-like 2 mediated lung resistance protein down regulation

引用

Cancer Drug Resistance 2020年第3期3卷 647-665页

作者： poornima Paramasivan Jothi Dinesh Kumar Rathinasamy Baskaran Ching Feng Weng Viswanadha Vijaya Padma Department of Biotechnology School of Biotechnology and Genetic EngineeringBharathiar UniversityCoimbatoreTamil Nadu 641046India. Department of Cellular and Molecular Physiology Institute of Translational MedicineUniversity of LiverpoolLiverpool L35TRUK. laboratory of Molecular Physiology Institute of BiotechnologyDepartment of Life SciencesNational Dong Hwa UniversityHualien 974Taiwan. Division of Science School of Applied SciencesUniversity of Abertay DundeeDundee DD11HGUK. Department of Bioinformatics and Medical Engineering Asia UniversityTaichung 41354Taiwan.

Aim:Development of multi drug resistance and dose limiting cardiotoxicity are hindering the use of Doxorubicin(Dox)in clinical *** dox efflux induced by lung resistance protein(lRP)over expression has been related to multi drug resistance phenotype in various *** alkaloid from lotus,Neferine(Nef)shows both anticancer and cardioprotective ***,we have investigated the interconnection between nuclear factor erythroid-derived 2-like 2(NRF2)and lRP in Dox resistance and how Nef can overcome Dox resistance in lung cancer cells by altering this ***:Anti-proliferative and apoptotic-inducing effects of Nef and Dox combination in Parental and Dox resistant lung cancer cells were determined in monolayers and 3D *** Dox was analyzed using flow cytometry,siRNA knockdown and western blot analysis were used to elucidate NRF2-lRP crosstalk mechanism.

关键词： Doxorubicin neferine reactive oxygen species lung resistance protein nuclear factor erythroid-derived 2-like 2 multidrug resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cortical thickness abnormalities in patients with first episode psychosis:a meta-analysis of psychoradiologic studies and replication in an independent sample

引用

Psychoradiology 2021年第4期1卷 185-198页

作者： Keren Wen Youjin Zhao Qiyong Gong Ziyu Zhu Qian li Nanfang Pan Shiqin Fu Joaquim Radua Eduard Vieta poornima Kumar Graham J.Kemp Bharat B.Biswal Huaxi MR Research Center(HMRRC) Department of RadiologyWest China Hospital of Sichuan UniversityChengdu 610041SichuanChina Research Unit of Psychoradiology Chinese Academy of Medical SciencesChengdu 610041SichuanChina Functional and Molecular Imaging Key laboratory of Sichuan Province Chengdu 610041SichuanChina Institut d’Investigacions Biom`ediques August Pi i Sunyer(IDIBAPS) Mental Health Research Networking Center(CIBERSAM)Barcelona 08036CataloniaSpain Centre for Psychiatric Research and Education Department of Clinical NeuroscienceKarolinska InstitutetSolna 171-77StockholmSweden Department of Psychosis Studies Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon WC2R 2LSUK Barcelona Bipolar Disorders and Depressive Unit Hospital ClinicInstitute of NeurosciencesUniversity of BarcelonaBarcelona 08036CataloniaSpain Center for Depression Anxiety and Stress ResearchMcLean HospitalBelmont 02478MAUSA Department of Psychiatry Harvard Medical SchoolBoston 02115MAUSA liverpool Magnetic Resonance Imaging Centre(liMRIC)and Institute of life Course and Medical Sciences University of LiverpoolLiverpool L693GEUK Department of Biomedical Engineering New Jersey Institute of TechnologyNewark 07102NJUSA The Clinical Hospital of Chengdu Brain Science Institute MOE Key Laboratory for NeuroinformationUniversity of Electronic Science and Technology of ChinaChengdu 610054SichuanChina

Background:Abnormalities of cortical thickness(CTh)in patients with their first episode psychosis(FEP)have been frequently reported,but findings are ***:To define the most consistent CTh changes in patients with FEP by meta-analysis of publishedwholebrain ***:The meta-analysis used seed-based dmapping(SDM)software to obtain the most prominent regional CTh changes in FEP,and meta-regression analyses to explore the effects of demographics and clinical *** meta-analysis results were verified in an independent sample of 142 FEP patients and 142 age-and sex-matched healthy controls(HCs),using both a vertex-wise and a region of interest analysis,with multiple comparisons ***:The meta-analysis identified lower CTh in the rightmiddle temporal cortex(MTC)extending to superior temporal cortex(STC),insula,and anterior cingulate cortex(ACC)in FEP compared with *** significant correlations were identified between CTh alterations and demographic or clinical *** results were replicated in the independent dataset ***:This study identifies a robust pattern of cortical abnormalities in FEP and extends understanding of gray matter abnormalities and pathological mechanisms in FEP.

关键词： psychoradiology first episode psychosis early psychosis cortical thickness meta-analysis seed-based d mapping

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Perimesencephalic Subarachnoid Hemorrhage in Pregnancy: A Case Report

引用

Maternal-Fetal Medicine 2022年第4期4卷 290-292页

作者： Stefania Ruggieri Maurizia Gatto Maria Annunziata Gentile Salvatore D'Oria Filippo tamma Domenico Caringella Alessandra Giocolano Chiara Taccalti Maurizio Guido Department of Obstetrics and Gynecology Catholic University of theSacred HeartPoliclinico Agostino Gemell iRCCSRome 00168Italy Department of Obstetrics and Gynecology General Regional Hospital"F.Miull"Acquaviva delle Fonti 70021Italy Department of Neurology General Regional Hospital"F.Miuli"AcquavivadelleFonti70021litaly Department of Neuroradiology General Regional Hospital“F.Miulli"Acquaviva delle Fonti 70021Italy Department of Neurosurgery General Regional Hospital"F.Miulli"Acquavivadelle Fonti 70021Italy MeSVA Department University of L'AquilaL'Aquila 67100Italy

Perimesencephalic subarachnoid hemorrhage (P-SAH) is a benign subset of subarachnoid hemorrhage. Only two cases of P-SAH during pregnancy have been reported in the literature. We describe a case of P-SAH detected at 29 weeks’ gestation, arose with severe bilateral frontal headache, neck rigidity, and vomiting. A diagnosis of P-SAH was confirmed on magnetic resonance angiography with no evidence of vascular malformation or bleeding sources and conservatively treated. Hemorrhage, vasospasm, and cerebellar edema observed on initial magnetic resonance angiography resolved after two months. The clinical course of P-SAH during pregnancy appears to be favorable. Our case shows for the first time in literature that magnetic resonance angiography is a valid diagnostic test for P-SAH during pregnancy that circumvents radiological risk associated with conventional imaging.

关键词： Subarachnoid hemorrhage Cerebrovascular diseases Headache Magnetic resonance angiography Pregnancy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：