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Contrast Agents and Contrast-Induced Nephropathy

International Journal of Clinical Medicine 2015年第7期6卷 451-457页

作者： Mohammad Hassan Ghadiani pooneh dehghan Department of Nephrology Taleghani Hospital Shahid Beheshti University of Medical Sciences Tehran Iran Taleghani Hospital Research Development Unit Department of Imaging Shahid Beheshti University of Medical Sciences Tehran Iran

Recent advances in medical sciences, especially in imaging, have dramatically increased the use of contrast agents. The constantly changing nature of medicine and the availability of new information, such as new pharmaceutical formulations, have necessitated periodic revisions and drafting of new guidelines for the safe use of intravenous contrast agents in radiology. This study examined the majority of guidelines, articles, and authoritative references available on the use of intravenous contrast agents in adults to reduce the risk of contrast-induced nephropathy. The search engines of PubMed, Web of Science, Scopus, and Google Scholar were used, and relevant English articles cited at least twice between 1979 and 2014 were studied. Review of the collected papers showed no consensus among them for guidelines on the incidence of contrast-induced nephropathy in patients at risk. Different formulas were used to calculate estimated glomerular filtration rate, which could be problematic in some cases. Further studies are needed for unification of existing guidelines.

关键词： Contrast-Induced Nephropathy Contrast Agents Acute Kidney Injury

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Nailfold Capillaroscopy Findings in Diabetic Patients (A Pilot Cross-Sectional Study)

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Open Journal of Pathology 2015年第2期5卷 65-72页

作者： Alireza Rajaei pooneh dehghan Zahra Farahani Rheumatology Loghman Hospital Shahid Beheshti University of Medical Sciences Tehran Iran Radiology Taleghani Hospital Shahid Beheshti University of Medical Sciences Tehran Iran Maternal Fetal and Neonatal Research Center Tehran University of Medical Sciences Tehran Iran

Background: Microcirculation is affected in diabetes mellitus and Microvascular abnormalities cause persistent diabetic complications. The aim of this study was nailfold capillaroscopic assessment to describe the pathological changes (morphological and structural) in capillary of a large series of patients with type 1 and 2 diabetes. Methods: A cross-sectional study was carried out in a Nailfold Capillaroscopy Center (Tehran-Iran) between 2011 and 2014. The study included 235 types 1, 2 diabetic patients. All patients underwent 10 nailfolds capillaroscopy examinations. Microvascular architecture, disturbances capillary distribution, capillary morphology, capillary density, efferent/afferent limb ratio, subpapillary venular plexus, and morphological abnormalities were evaluated. Conclusions were stated as normalor scleroderma pattern. Results of patients’ capillaroscopic images were recorded and analyzed quantitatively and qualitatively. P value < 0.05 was considered as statistical significance. Results: of all participants with mean age 59.91 ± 12.39, 183 cases (77.9%) were female and 52 (22.1%) were male. Tortuosity of capillaries was more often observed in our subjects (235 cases) followed by angiogenesis (171 cases). Normal and early scleroderma patterns were observed in 195 (83.0%) and 40 cases (17.0%). Based on P values, altered micro vascular architecture, capillary distribution and capillary morphology were more frequent in patients with scleroderma pattern in comparison to patients with normal pattern (P value < 0.05). Morphological abnormalities except from neo formation capillary and mega capillary were also significantly more common in patients with scleroderma pattern than patients in counterpart group (P value < 0.05). Conclusion: Nailfold capillaroscopy as a non-invasive, diagnostic and prognostic method may potentially affect on diabetes outcome and control.

关键词： Diabetes Nail Fold Capillaroscopy Normal Pattern Scleroderma PatternDiabetes Scleroderma Pattern

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Hybrid Ameloblastoma in the Anterior Man-dible

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Advances in Computed Tomography 2015年第3期4卷 42-46页

作者： Mandana Pourian Mersad Mehranahad pooneh dehghan Radiology Department Rasool Akram Hospital Iran University of Medical Sci-ences Tehran Iran Taleghani Hospital Research Department Shahid Beheshti University of Med-ical Sciences Tehran Iran

Ameloblastoma—a benign epithelial odontogenic tumor-histologically occurs in different patterns, the most common of which are plexiform and follicular. “Hybrid” ameloblastoma is a variant in which areas of follicular or plexiform pattern (generally called convention alameloblastoma) coexist with areas of pronounced stromal desmoplasia (desmoplastic ameloblastoma). They most often occur in the mandibular ramus. We present a case of “hybrid” lesion—desmoplastic and conventional ameloblastoma—in the anterior mandible, focusing on its’ imaging features.

关键词： Odontogenic Tumor Hybrid Conventional Desmoplastic Ameloblastoma

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Leontiasis Ossea Following Secondary Hyperparathyroidism and Hemodialysis

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Journal of Biosciences and Medicines 2015年第7期3卷 54-59页

作者： pooneh dehghan Ali Zahiri Mohammad Ali Karimi Mohammad Hossein Ghadiani Department of Radiology Taleghani Hospital Shahid Beheshti Medical University Tehran Iran Department of Nephrology Taleghani hospital Shahid Beheshti Medical University Tehran Iran

Leontiasis ossea is a rare medical condition which is characterized by an overgrowth of the facial and cranial bones secondary to chronic renal failure and secondary hyperparathyroidism. We reported a case of leontiasis ossea with history of secondary hyperparathyroidism due to end-stage renal disease on regular hemodialysis. A 37-year-old female with end-stage renal disease from lupus disease on regular hemodialysis complaining of progressive facial deformity for two years causing dyspnea, dental malocclusion and dysarthria with the final diagnosis of uremic leontiasis ossea. It is important to recognize features of leontiasis ossea, as it may result in life-threatening upper airway obstruction and compressive cranial neuropathy while after parathyroidectomy, facial changes can be stabilized or improved mildly.

关键词： Hyperparathyroidism Hemodialysis Leontiasis Ossea

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