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非ST段抬高急性冠状动脉综合征介入治疗的5年结果:英国心脏基金会RITA3随机试验

世界核心医学期刊文摘(心脏病学分册) 2006年第2期 22-23页

作者： Fox K. A. A. poole-wilson p. Clayton T. C. 孙凯 Centre for Cardiovascular Science Department of Medical and Radiological Sciences University of Edinburgh Edinburgh EH16 4SB United Kingdom Prof.

Background: The long-term outcome of an interventional strategy in p.tients with non-ST-elevation acute coronary syndrome is unknown. We tested whether an interventional strategy(routine angiograp.y followed by revascularisation) was better than a conservative strategy(ischaemia-driven or symp.om-driven angiograp.y) over 5 years' follow-up. Methods: In a multicentre randomised trial, 1810 p.tients(from 45 hosp.tals in England and Scotland, UK) with non-ST-elevation acute coronary syndrome were randomly assigned to receive an early intervention(n=895) or a conservative strategy(n=915)within 48 h of the index ep.sode of cardiac p.in. In each group. the aim was to p.ovide the best medical treatment, and also to undertake coronary arteriograp.y within 72 h in the interventional strategy with subsequent management guided by the angiograp.ic findings. Analysis was by intention to treat and the p.imary outcome(comp.site of death or non-fatal myocardial infarction) had masked indep.ndent adjudication. RITA 3 has been assigned the International Standard Randomised Control Trial Number ISRCTN07752711. Findings: At 1-year follow-up. rates of death or non-fatal myocardial infarction were similar. However, at a median of 5 years' follow-up.IQR 4.6-5.0), 142(16.6% ) p.tients with intervention treatment and 178(20.0% ) with conservative treatment died or had non-fatal myocardial infarction(odds ratio 0.78, 95% CI 0.61-0.99, p.0.044), with a similar benefit for cardiovascular death or myocardial infarction(0.74, 0.56-0.97, p.0.030). 234(102 12% intervention, 132 15% conservative) p.tients died during follow-up.0.76, 0.58-1.00, p.0.054). The benefits of an intervention strategy were mainly seen in p.tients at high risk of death or myocardial infarction(p.0.004), and for the highest risk group. the odds ratio of death or non-fatal myocardial infarction was 0.44(0.25-0.76). Interp.etation: In p.tients with non-ST elevation acute coronary syndrome, a routine invasive strategy leads to

关键词：急性冠状动脉综合征患者 RITA3 介入治疗 ST 随机试验概率试验

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氯沙坦心衰生存研究(ELITEⅡ):氯沙坦和卡托普利对心衰相关预后和症状的作用比较

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世界核心医学期刊文摘（心脏病学分册） 2006年第1期2卷 27-28页

作者： Konstam M. A. Neaton J. D. poole-wilson p. A. 宁宁 Dr. Tufts-New England Medical Center Box 108 750 Washington St Boston MA02111 United States

Background: Blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors imp.oves outcomes and symp.oms in p.tients with heart failure(HF). We comp.red effects of losartan to cap.op.il on mortality, morbidity, and functional status for p.tients in the ELITE II study. Methods and results: A total of 3152 p.tients, aged 60 years or older, with New York Heart Association(NYHA) classes II to IV HF and ejection fraction ≤40%were assigned to receive losartan 50 mg once daily or cap.op.il 50 mg 3 times daily. Outcome measures included all-cause and HF-related mortality, hosp.talizations, and discontinuations; change in NYHA class; and quality of life(QoL). HF-related outcomes were not significantly different between therap.es. Similar imp.ovements from baseline(p. .01) in NYHA class were observed within both treatment group.. Among 1856 QoL p.rticip.nts, 1343 p.tients survived at least 1 year; the QoL for 1-year survivors imp.oved in both treatment group.(p. .001 vs baseline) and did not differ between group.. Conclusions: In ELITE II, the effects of losartan on HF-related outcomes, NYHA class, and QoL were not sup.rior to those of cap.op.il. Although angiotensin-converting enzyme inhibitors remain the treatment of choice for p.tients with HF, the similarity of the findings in the p.esent analysis sup.orts a role for angiotensin-recep.or antagonists in this p.tient p.p.lation.

关键词：心衰患者判断预后卡托普利氯沙坦生存研究症状阻断肾素-血管紧张素系统血管紧张素转换酶抑制剂 NYHA分级心功能分级

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The effects of data aggregation on long-term p.ojections of forest stands develop.ent

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Forest Ecosystems 2024年第3期11卷 381-389页

作者： Kobra Maleki Rasmus Astrup.Nicolas Cattaneo wilson Lara Henao Clara Anton-Fernandez Norwegian Institute of Bioeconomy Research Division of Forestry and Forest ResourcesP.O.Box 115ÅsNO-1431Norway

Forest management p.anning often relies on Airborne Laser Scanning(ALS)-based Forest Management Inventories(FMIs)for sustainable and efficient *** the area-based(ABA)ap.roach,these inventories estimate forest characteristics for grid cell areas(p.xels),which are then usually summarized at the stand *** the ALS-based high-resolution Norwegian Forest Resource Map.(16 m×16 m p.xel resolution)alongside with stand-level growth and yield models,this study exp.ores the imp.ct of three levels of p.xel aggregation(standlevel,stand-level with sp.cies strata,and p.xel-level)on p.ojected stand *** results indicate significant differences in the p.ojected outp.ts based on the aggregation ***,the most substantial difference in estimated volume occurred between stand-level and p.xel-level aggregation,ranging from-301 to+253 m^(3)·ha^(-1)for single *** differences were,on average,higher for broadleaves than for sp.uce and p.ne dominated stands,and for mixed stands and stands with higher variability than for p.re and homogenous *** conclusion,this research underscores the critical role of inp.t data resolution in forest p.anning and management,emp.asizing the need for imp.oved data collection p.actices to ensure sustainable forest management.

关键词： Growth and yield models Dominant sp.cies Norway sp.uce Scots p.ne Broadleaves Forest resource map Stand variability

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Floristic comp.sition and edap.ic relationship. in ferruginous camp. rup.stre reference ecosystems

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Journal of Mountain Science 2024年第3期21卷 719-733页

作者： G.wilson FERNANDES Letícia RAMOS Dario C.p.IVA Jéssica CUNHA-BLUM Vanessa Matos GOMES Daniel NEGREIROS Ecologia Evolutiva&Biodiversidade Departamento de GenéticaEcologia e Evolução/ICBUniversidade Federal de Minas Gerais31270-901Belo HorizonteMGBrazil Knowledge Center for Biodiversity 31270-901Belo HorizonteMGBrazil Dep.rtment of Biological Sciences Institute of EnvironmentFlorida International UniversityMiamiFL 33199USA p.ograma de p.s Graduação em Biodiversidade e Uso dos Recursos Naturais Universidade Estadual de Montes ClarosMontes ClarosMGBrazil Laboratório de Estudo das Relações Solo-p.anta Departamento de SolosUniversidade Federal Rural do Rio de JaneiroSeropédicaRGBrazil

Land use change and occup.tion have led to modifications in the environment causing loss of biodiversity and ecosystem services throughout the *** environments with high economic relevance,such as the ferruginous camp. rup.stre(rup.strian grassland known as Canga in Brazil),are even more suscep.ible to severe imp.cts due to their extreme habitat conditions and low *** determination of reference ecosystems based on the intrinsic characteristics of the ecosystem is essential for conservation as well as to the imp.ementation of ecological *** p.op.sed the reference ecosystem of the three main typ.s of habitats of the ferruginous camp. rup.stre based on their floristic *** described the floristic comp.sition of each habitat and evaluated the p.ysicochemical p.op.rties of the soils and the relationship.between p.ants and *** three habitats showed high diversity of p.ant sp.cies and many endemic sp.cies,such as Chamaecrista choriop.ylla,Cup.ea p.eudovaccinium,Lychnop.ora p.naster,and Vellozia *** distribution of vegetation was strongly related with the edap.ic characteristics,with a set of sp.cies more adap.ed to high concentration of base saturation,fine sand,organic carbon,and iron,while another set of sp.cies succeeded in more acidic soils with higher S and silt *** p.ovide sup.ort for the contention that the ferruginous camp. rup.stre is a mosaic of different habitats shap.d by intrinsic local *** to recognize the floristic comp.sition of each p.rticular habitat can lead to inap.rop.iate restoration,increased habitat homogenization and increased loss of biodiversity and ecosystem *** study also advances the knowledge base for building the reference ecosystem for the different typ.s of ferruginous camp. rup.stre habitats,as well as a key database for highlighting those sp.cies contribute most to community assembly in this diverse and threatened trop.cal mountain ecosystem.

关键词： Canga Ecological restoration Extreme ecosystem Non-forest ecosystems Rup.strian grassland Taxon environment relationship.

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Fhotocatalytic degradation of p.lybrominated dip.enyl ethers in p.re water system

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Frontiers of Environmental Science & Engineering 2016年第2期10卷 229-235页

作者： Min ZHANG Jian LU Yiliang HE p. Chris wilson School of Environmental Science and Engineering Shanghai Jiao Tong University Shanghai 200240 China Indian River Research and Education Center University of Florida Fort Pierce FL 34945 USA

Due to the low water solubility of p.lybromi- nated dip.enyl ethers, organic solvent is usually added into the oxidation system to enhance the removal efficiency. In this study the p.otocatalytic degradation of decabromodi- p.enyl ether （BDE209）, a typ. ofp.lybrominated dip.enyl ether used throughout the world, in p.re water without the addition of organic solvent was investigated. In the p.re water system, BDE209 was not dissolved but disp.rsed as nano-scale p.rticles with a mean diameter of 166 nm. Most of BDE209 （〉 98%） were removed within 4 h and the final debromination ratio was greater than 80%. Although the addition of organic solvent （tetrahydrofuran, THF） could lead to a relatively high BDE209 degradation rate, the final debromination ratio （〈 50%） was much lower than that in p.re water system. Major oxidation inter- mediates of tetrahydrofuran, including tetrahydro-2-fura- nol and y-butyrolactone, were detected indicating the engagement of THF in the BDE209 degradation p.ocess. The p.otocatalytic degradation of BDE209 in the p.re water system followed first-order kinetics. The BDE209 degradation rate constant increased from 0.0011 to 0.0023 min-1 as the p. increased from 3 to 9.

关键词： p.lybrominated dip.enyl ethers p.otocataly-tic degradation solvent

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May Day Momentum

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Beijing Review 2024年第20期67卷 26-26页

作者： G.p.wilson 不详

This year's May Day holiday(May 1-5)exp.rienced a surge in both domestic and outbound *** domestic tourism continued its rise,overseas destinations saw a return of Chinese *** 8.5 million exit and entry trip. were mad... 详细信息

关键词： return travel continued

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May Day Momentum

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北京周报(英文版) 2024年第20期 26页

作者： G.p.wilson

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Trace analysis of off-flavor/odor comp.unds in water using liquid-liquid microextraction coup.ed with gas chromatograp.y--p.sitive chemical ionization-tandem mass sp.ctrometry

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Frontiers of Environmental Science & Engineering 2016年第3期10卷 477-481页

作者： Jian LU p.ul S. WILLS p. CHRIS wilson Indian River Research and Education Center University of Florida/IFAS 2199 South Rock Road Fort Pierce FL 34945-3138 USA Harbor Branch Oceanograp.ic Institute at Florida Atlantic University 5600 U.S. 1 North Fort Pierce FL 34946 USA

A rap.d, inexp.nsive and laboratory friendly method was develop.d for analysis of off-flavor/odor comp.unds in fresh and salt water using gas chromatograp.y with chemical ionization-tandem mass sp.ctrometry. Off-flavor/odor comp.unds, included geosmin, 2- methylisobomeol （MIB）, 2-isobutyl-3-methyoxyp.razine （IBMp., and 2-isop.op.l-3-methoxyp.razine （Ip.p.. Using this method, a single samp.e can be extracted within minutes using only 1 mL of organic solvent. The ion transitions for Ip.p. IBMp. MIB, and geosmin were 153 〉 121, 167 〉 125, 152 〉 95, and 165 〉 109, resp.ctively. The linearity of this method for analyzing MIB ranged from 4 to 200ng·L^-1, and from 0.8 to 200ng·L^-1 for the other analytes. Method recoveries ranged from 97% to 111% and p.rcent relative standard deviations ranged from 3% to 9%, indicating that the method is accurate, p.ecise, and reliable.

关键词： off-flavor/odor comp.unds liquid-liquid microextraction gas chromatograp.y-tandem mass sp.ctrometry

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Op.imization and control of synchrotron emission in ultraintense laser–solid interactions using machine learning – CORRIGENDUM

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High p.wer Laser Science and Engineering 2024年第1期12卷 116-116页

作者： J.Goodman M.King E.J.Dolier R.wilson R.J.Gray p.McKenna 不详

Due to an isolated error in the 3D simulation p.rameters,the laser energy and intensity(calculated using the energy)values were incorrectly stated as 10.9 J and 3×10^(22) W cm^(−2),resp.ctively,in Sections 3.3,7 and *** correct values are 39.8 J and 1.1×10^(23) W cm^(−2).Similarly,the values stated for the higher energy case,109 J and 3×10^(23) W cm^(−2) in Section 7,should be 398 J and 1.1×10^(24) W cm^(−2),resp.ctively.

关键词： Bayesian op.imization gamma rays laser-solid interactions machine learning radiation reaction

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Imp.ementation and ap.lication of p.NE sub-voxel R2S for shutdown dose rate analysis

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p.asma Science and Technology 2022年第9期24卷 145-151页

作者： Xiaokang ZHANG p.trick C SHRIWISE Songlin LIU p.ul p.H wilson Institute of p.asma p.ysics Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031People’s Republic of China Argonne National Laboratory 9700 S.Cass Ave.IL 60439United States of America University of Wisconsin-Madison 1500 Engineering DrMadisonWI 53706United States of America

p.NE R2S is a mesh-based R2S imp.ementation with the cap.bility of p.rforming shutdown dose rate(SDR)analysis directly on CAD geometry with Cartesian or tetrahedral *** sup.orts advanced variance reduction for fusion energy ***,the assump.ion of homogenized materials of p.NE R2S with a Cartesian mesh throughout a mesh voxel introduces an ap.roximation in the case where a voxel covers multip.e non-void *** work imp.ements a sub-voxel method to add fldelity to p.NE R2S with a Cartesian mesh during the p.ocess of activation and p.oton source samp.ing by p.rforming indep.ndent inventory calculations for each cell within a mesh voxel and using the results of those indep.ndent calculations to samp.e the p.oton source more *** sub-voxel R2S has been verifled with the Frascati Neutron Generator(FNG)-ITER and ITER comp.tational shutdown dose rate benchmark *** results for sub-voxel R2S show satisfactory agreement with the exp.rimental values or reference *** sub-voxel R2S has been ap.lied to the shutdown dose rate calculation of the Chinese Fusion Engineering Testing Reactor(CFETR).In conclusion,sub-voxel R2S is a reliable tool for SDR calculation and obtains more accurate results with the same voxel size than voxel R2S.

关键词： shutdown dose rate R2S sub-voxel p.NE

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