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Confinement effect on CO_(2)and CH_(4)permeability in shale

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Energy Geoscience 2024年第1期5卷 256-263页

作者： Vikram Vishal Tuli bakshi Computational and Experimental Geomechanics Laboratory Department of Earth SciencesIndian Institute of Technology BombayMumbai400076India National Centre of Excellence in Carbon Capture and Utilization Indian Institute of Technology BombayMumbai400076India

Gas flow in shales follows a number of physical mechanisms that include Knudsen diffusion,Darcy flow,and adsorption in the matrix and micro *** aim of the study is to resolve the interplay of gas transport in these media at increased effective stress as well as net pore *** this research,we investigated the nature of gas transport in the matrix of shale by sending He,CH_(4)and CO_(2)gases through a transient upstream pressure pulse decay instrument.A series of experiments were conducted at constant pore pressures and a gradually increasing confining *** same study was done in three different scenarios,injecting He,CO_(2)and CH_(4).At a constant pore pressure,gas permeability appears to decrease with an increasing confining pressure and effective *** increasing effective stress,the slip factor also decreases along with the *** decrease in slip could be attributed to prestressing,that is likely to create new *** the three purged gases,permeability of shale to CH_(4)is the highest,and that to CO_(2)is the lowest owing to its high *** permeability of CH_(4)against He,could be attributed to the dual transport mechanism.

关键词： Energy Porous media Gas transport Effective stress

Conservation of an important montane bamboo Thamnocalamus falconeri, *** Munro through axillary bud proliferation

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Journal of Forestry Research 2015年第1期26卷 179-185页

作者： Meena bakshi Chandrakant Tiwari Sajad Razvi Plant Physiology Discipline Botany DivisionForest ResearchInstitute

Thamnocalamus falconeri, Hook.f. ex Munro.,an important bamboo species belonging to the family Poaceae, locally known as Ringal, occurs in the hills of Uttarakhand, India. This species has been traditionally exploited by local communities to support their *** needs of the hill villages impose unsustainable pressure on natural stands of Ringal in the Uttarakhand hills and forests have been degraded. The long history of excessive cutting of Ringal from natural forests and the lack of replanting threaten villager livelihoods. Replanting is required to conserve the species. We propose a protocol for generation of planting material through axillary bud proliferation for multiplication and conservation of this species. We collected offsets/rhizomes from a natural stand of T. falconeri in the Chopta Mandal areas（Chamoli district, India）. These were planted at sites of varied elevation and fresh single nodal segments were collected from them as explants. Different sterilization treatments were assessed to combat contamination. Among these, treatment of 0.1 %Hg Cl2 followed by 5 % Na OCl, proved best. Among two cytokinin treatments, viz. BAP and Kinetin, singly or in combination, BAP alone（5 mg L-1） proved superior and resulted in 100 % bud break. BAP-supplemented MS media yielded maximum vigorous shoot formation（90 %）and maximum number of shoots（8.9）. Subculturing of shoots on the same medium with similar BAP treatment（5 mg L-1BAP） enabled continuous production of healthy shoots at similar frequency. Maximum rooting（100 %）was recorded on half-strength MS medium supplemented with 5 mg L-1IBA. Micropropagated plants were hardened and acclimatized in soil mixture（2：1：1） and then transplanted to field sites（Magra, Uttarakhand, 1,834 m）.Eight to ten months after field transplantation we recorded100 % survival of transplanted material. This micropropagation protocol could be used successfully for raising a stock of genetically homogenous plant material in bulk

关键词： Thamnocalamus falconeri Micropropagation MS medium Axillary bud proliferation Hormones

Coumarin and eugenol ameliorate LPS-induced inflammation in RAW 264.7 cells via modulating the NLRP3 inflammasome pathway

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Asian Pacific Journal of Tropical Biomedicine 2024年第1期14卷 40-46页

作者： Jyotsana bakshi Somnath Singh KP Mishra DRDO Defence Institute of Physiology and Allied Sciences DelhiIndia

Objective:To investigate the underlying mechanism of anti-inflammatory action of coumarin and eugenol in lipopolysaccharide(LPS)-stimulated RAW 264.7 ***:RAW 264.7 cells were treated with 2.5μg/mL of LPS,50μM of coumarin,and 50μM eugenol for 24 *** viability of the cells was assessed using MTT *** production of nitric oxide was determined using Griess reagent and DCFH-DA was used to measure the production of reactive oxygen *** protein expression of NLRP3,IL-1β,NF-κB,and cyclooxygenase 2 was assessed using Western blot ***:Coumarin and eugenol showed anti-inflammatory effects against LPS-induced inflammatory response by ameliorating the expression of NLRP3 inflammasome and NF-κB,which further led to a subsequent reduction in IL-1β,nitric oxide,and reactive oxygen ***:Coumarin and eugenol exert their anti-inflammatory activities by modulating the NLRP3 inflammasome pathway and NF-κ*** compounds may have promising therapeutic applications for the treatment of various inflammatory diseases.

关键词： Inflammation Cytokines Coumarin Eugenol NLRP3 LPS

Assessment of genetic diversity in Dalbergia sissoo clones through RAPD profiling

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Journal of Forestry Research 2011年第3期22卷 393-397页

作者： Meena bakshi Arvind Sharma Plant Physiology Discipline Botany Division Forest Research Institute Dehradun 248 006 INDIA

We studied the genetic polymorphism among 29 clones of shisham （Dalbergia sissoo Roxb） belonging to different geographic regions using random amplified polymorphic DNA （RAPD） markers. Out of 30 primers used, only 20 primers generated polymorphism in amplified product. In total 232 bands were amplified with 20 primers, of which 192 （82%） were polymorphic with an average of 9.6 bands/primer. The resolving power （Rp） ranged from 2.14 （Primer 5） to 11.93 （Primer 4）. Primer 4 and Primer 3 possessed high Rp value. Polymorphism information content （PIC） ranged from 0.15 （Primer 5） to 0.37 （Primer 4）. Primer 4 amplified total 18 bands in 29 genotypes with PIC value of 0.37 hence; this set of primer was most informative. The similarity coefficient analysis revealed two clusters. The first cluster comprised of only 10 clones and the second major cluster comprised of 19 clones. The genetic similarity among 29 clones ranged from 25.86% （clone 10 and 235） to 100% （clone 19 and 59）, suggesting a wide genetic base in shisham clones.

关键词： clones clonal seed orchard Dalbergia sissoo RAPD polymorphism information content resolving power

Growth and heritability estimates among clones of Dalbergia sissoo Roxb. in a clonal seed orchard

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Forestry Studies in China 2011年第3期13卷 211-217页

作者： Arvind SHARMA Meena bakshi Division of Genetics and Tree Propagation Forest Research Institute Dehradun-248006 (Uttarakhand) India Plant Physiology Discipline Botany Division Forest Research Institute Dehradun-248006 (Uttarakhand) India

The study of genetic variability is a prerequisite for any tree improvement program. Screening of clones showing the effect of dominance in growth and tree form is essential to identify productive clones, matched to sites. Our study performed in a clonal seed orchard at Lacchiwala of India, represented by 31 clones of Dalbergia sissoo （Shisham） Roxb. from diverse locations revealed significant variability at the 0.1% level of significance in various morphological traits. At the age of 13 years, clone 196 （Gonda） revealed maximum height of 20.2 m and a girth at breast height of 74.2 cm. The five identified clones viz. 196, 198, 192, 123 and 235 were well adapted to the climatic conditions of this zone, hence survived well and showed good performance compared to other clones. Heritability estimates of 87%, 83% and 80% for height, crown width and crown length respectively coupled with high genetic gains indicated strong genetic control of these variables. A correlation matrix of various growth attributes revealed positive correlation among these attributes. On the basis of the entire set of growth variables, the clones were grouped into two major clusters with three subgroups.

关键词： clone cluster correlation Dalbergia sissoo genetic gain heritability

Development and validation of an HPLC-UV method for analysis of methylphenidate hydrochloride and loxapine succinate in an activated carbon disposal system

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Journal of Pharmaceutical Analysis 2018年第6期8卷 349-356页

作者： pooj. bakshi Andrew Korey William Fowler Ajay K.Banga Department of Pharmaceutical Sciences Mercer UniversityAtlantaGA 30341USA Verde Environmental Technologies 12900 Whitewater DriveMinnetonkaMN 55343USA

Unused medications have the possibility of being abused, causing serious harm to individuals who were not prescribed the drug. The Food and Drug Administration(FDA) recommends the proper disposal of unused prescribed medications to maintain safety and prevent environmental hazards. However, many of the current disposal techniques do not properly address safety. A drug disposal pouch containing granular activated carbon offers a unique disposal method to deactivate residual or expired medication in a convenient, effective, and safe manner. A robust and validated method for methylphenidate hydrochloride and loxapine succinate was developed using high-performance liquid chromatography(HPLC) and the deactivation efficiency of the disposal system was tested. Methylphenidate hydrochloride was analyzed on a C18 analytical column(250 mm ?4.60 mm, 100?) using acetonitrile-water(0.05%(v/v) trifluoroacetic acid) as the mobile phase at a flow rate of1.0 mL/min with a run time of 15 min and retention time of 7.8 min. Loxapine succinate was separated on a C8100?(250 mm ? 4.6 mm, 5 mm) column maintained at 25 °C using a flow rate of 1.0 mL/min. The run time was 10 min and the retention time of the drug was around 4.6 min. Mobile phase was composed of acetonitrile and water(0.3% triethylamine) at pH 3.0 as 40:60(v/v). Reference standard solutions(100 mg/mL) for both drugs were prepared by dissolving in mobile phases. These methods provide good linearity(R2? 0.999) over the range of 5–100 mg/mL for methylphenidate hydrochloride and 0.1–100 mg/mL for loxapine succinate. The assay methods were successfully applied to study the deactivation of these drugs.

关键词： Methylphenidate hydrochloride Loxapine succinate Activated carbon Analytical method development FDA drug disposal

Perspectives of newborn hearing screening in resource constrained settings

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Journal of Otology 2020年第4期15卷 174-177页

作者： Soumyajit Das Ramesh Seepana Satvinder Singh bakshi Department of ENT All India Institute of Medical SciencesMangalagiriAndhra PradeshPIN e 522503India

Newborn hearing screening is an effective strategy for early identification of hearing loss in the newborn which result in early intervention and best *** implementing universal screening strategy is a challenge in many resource constrained *** are various limitations towards successful implementation of hearing screening program in the developing *** cost effectiveness of the screening program also needs to be considered in a resource constrained *** attempt to provide a viewpoint that can be potentially helpful for the successful implementation of hearing screening in a resource constrained settings of the developing countries.

关键词： Newborn hearing screening Universal Developing countries High risk Cost effectiveness

Editorial： special issue on “resilient networks： modeling, design, and applications”

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Digital Communications and Networks 2018年第1期4卷 1-2页

作者： Atilla Elci Sambit bakshi Manmath N. Sahoo Department of Computer Science and Engineering National Institute of Technology Rourkela Odisha 769 008 India

The design of resilient networks is of utmost importance today, owing to the wide range of safety-critical applications. Resilient networks try to guarantee an acceptable level of Quality of Service （QoS）, even in cases of challenges and faults in the system. The causes of obstruction in normal system operation range from simple misconfiguration, hardware failures, and software failures to intended attacks and natural disasters.

关键词： special issue resilient networks

Evolution of intrinsic nuclear structure in medium mass even-even Xenon isotopes from a microscopic perspective

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Chinese Physics C 2020年第7期44卷 147-156页

作者： Surbhi Gupta Ridham bakshi Suram Singh Arun Bharti G.H.Bhat J.A.Sheikh Department of Physics University of JammuJammu-180006India Department of Physics and Astronomical Sciences Central University of JammuSamba-181143India Department of Physics SP CollegeCluster University Srinagar-190001India Cluster University Srinagar-Jammu and Kashmir 190001 India

In this study,the multi-quasiparticle triaxial projected shell model(TPSM)is applied to investigateγ-vibrational bands in transitional nuclei of *** report that each triaxial intrinsic state has aγ-band built on *** TPSM approach is evaluated by the comparison of TPSM results with available experimental data,which shows a satisfactory *** energy ratios,B(E2)transition rates,and signature splitting of theγ-vibrational band are calculated.

关键词： triaxial projected shell model triaxiality yrast spectra band diagram back-bending staggering reduced transition probabilities