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Dynamics of transmission of COVID-19 cases and household contacts:A prospective cohort study

Journal of Acute Disease 2021年第4期10卷 162-168页

作者： Priyanka Rajmohan ponnu jose Jubina Bency Anthoora Thodi Joe Thomas Lucy Raphael Swathi Krishna Unnikrishnan Uttumadathil Gopinathan Praveenlal Kuttichira Departments of Community Medicine Jubilee Mission Medical College and Research InstituteThrissurKeralaIndia Departments of Psychiatry Jubilee Mission Medical College and Research InstituteThrissurKeralaIndia

Objective:To study the transmission dynamics of coronavirus disease 2019(COVID-19)among 101 confirmed cases and their 387 household contacts and to determine risk factors associated with secondary attack among the household ***:A prospective cohort study was conducted from January 1st 2021 to February 28th 2021,among 101 SARS-CoV-2 cases and 387 household contacts who were followed up for 14 days from the last day of contact with the index case of *** dynamics of disease transmission was estimated,and factors affecting transmission risk were ***,the association between various factors and household secondary attack rate was ***:The median incubation period was found to be 5 days,and the observed reproductive number(R)was found to be 1.63(95%CI:1.28-1.98).The mean household secondary attack rate was 40.7%.Contacts with comorbidities like diabetes mellitus,hypertension,dyslipidemia,and hypothyroidism had significantly higher attack rates(P<0.05).Conclusions:As new variants of SARS-CoV-2 emerges,it is crucial to know the trasmission *** study shows a high secondary attack rate of COVID-19 among household contacts that must be closely monitored.

关键词： Dynamics Transmission COVID-19 Kerala Prospective cohort

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