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Bariatric surgery in old age:a comparative study of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in an Asia centre of excellence

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The Journal of Biomedical Research 2015年第2期29卷 118-124页

作者： chih-Kun Huang Amit Garg Hsin-chih Kuao po-chih chang Ming-Che Hsin Bariatric & Metabolic International(B.M.I) Surgery Centre E-Da Hospital Department of Health Management I-Shou University

Bariatric surgery has been proved to be the safest and efficient procedure in treating morbid obese patients,but data is still lacking in the elderly *** aim of our study was to compare the safety and efficacy of laparoscopic Roux-en-Y gastric bypass（LRYGB） and sleeve gastrectomy（LSG） in patients aged more than 55 *** performed2 a retrospective review of a prospectively collected *** patients with body mass index（BMI） §32 kg/mand aged more than 55 years undergoing LRYGB or LSG in BMI Surgery Centre,E-Da Hospital between January 2008 and December 2011 with at least one year of follow up were included for the ***,peri-operative data,weight loss and surgical complications were all recorded and *** age and BMI of these 68 patients22（22 males and 46 female） were 58.8 years（55-79 years） and 39.5 kg/m（32.00-60.40 kg/m）.LRYGB was performed in 44 patients and LSG in 24 *** two groups were comparable in their preoperative BMI,American Society of Anaesthesia（ASA） score and gender *** patients were significantly older than patients receiving *** proportion of type 2 diabetes preoperatively was significantly higher in LRYGB patients as compared to LSG patients（88.63% vs.50%; P,0.01）.The prevalence of other co-morbidities was similar and comparable2 between the *** BMI in the LRYGB and LSG groups at the end of 1 year were 28.8 kg/mand228.2 kg/m,respectively,and there was no statistically significant difference in mean percentage of excess weight loss（%EWL） at 1 *** percentage of resolution of diabetes was significantly higher in LRYGB（69.2%） as compared to LSG（33.3%）.On the other hand,there was no statistical difference in the percentage of resolution of hypertension,hyperlipidemia and fatty liver *** overall morbidity and re-operation rate was higher in LRYGB *** morbidly elderly patients,both surgeries achieved good weight loss and resolution of *** is s

关键词： obesity metabolic surgery Roux-en-Y gastric bypass laparoscopic sleeve gastrectomy effiacy safety

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Multiple bowel intussusceptions from metastatic localized malignant pleural mesothelioma:A case report

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World Journal of Gastroenterology 2010年第31期16卷 3984-3986页

作者： Hsien Liu Yu-Jen Cheng Hsin-Pao Chen Jau-Chung Hwang po-chih chang Division of General Surgery Department of Sur-geryE-DA Hospital/I-Shou University Division of Thoracic Surgery Department of SurgeryE-DA Hospital/I-Shou University Division of Colon and Rectal Surgery Depart-ment of SurgeryE-DA Hospital/I-Shou University Department of Pathology E-DA Hospital/I-Shou University

Localized malignant pleural mesothelioma (LMPM) is a rare occurrence, and gastrointestinal intra-luminal metastases have not previously been reported. Herein, we report a patient with LMPM who presented with a local recurrence 10 mo after initial en bloc surgical resection. Abdominal computed tomography was performed for intractable, vague abdominal pain with episodic vomiting, which showed a "target sign" over the left lower quadrant. Laparotomy revealed several intra-luminal metastatic tumors in the small intestine and colon and a segmental resection of metastatic lesions was performed. Unfortunately, the patient died of sepsis despite successful surgical intervention. Though local recurrence is more frequent in LMPM, the possibility of distant metastasis should not be ignored in patients with non-specifi c abdominal pain.

关键词： Localized malignant pleural mesothelioma Intussusception Distant metastasis

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Solving Cauchy Issues of Highly Nonlinear Elliptic Equations Using a Meshless Method

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Computers, Materials & Continua 2022年第8期72卷 3231-3245页

作者： chih-Wen chang Department of Mechanical Engineering National United UniversityMiaoli360302Taiwan

In this paper,we address 3D inverse Cauchy issues of highly nonlinear elliptic equations in large cuboids by utilizing the new 3D homogenization functions of different orders to adapt all the specified boundary *** also add the average classification as an approximate solution to the nonlinear operator part,without requiring to cope with nonlinear equations to resolve the weighting coefficients because these constructions are owned many conditions about the true *** unknown boundary conditions and the result can be retrieved straightway by coping with a small-scale linear system when the outcome is described by a new 3D homogenization function,which is right to find the numerical solutions with the errors smaller than the level of noise being put on the over-specified Neumann conditions on the bottom of the ***,note that the new homogenization functions method(HFM)does not require dealing with the regularization and highly nonlinear *** robustness and accuracy of the HFM are verified by comparing the recovered results of several numerical experiments to the exact solutions in the entire region,even though a very large level of noise 50%is imposed on the over specified Neumann *** numerical errors of our scheme are in the order of O(10^(−1))-O(10^(−4)).

关键词： Inverse cauchy problems homogenization functions method(HFM) 3D highly nonlinear elliptic equations 3D homogenization functions

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A Meshless Method for Retrieving Nonlinear Large External Forces on Euler-Bernoulli Beams

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Computers, Materials & Continua 2022年第10期73卷 433-451页

作者： chih-Wen chang Department of Mechanical Engineering National United UniversityMiaoli360302Taiwan

We retrieve unknown nonlinear large space-time dependent forces burdened with the vibrating nonlinear Euler-Bernoulli beams under varied boundary data,comprising two-end fixed,cantilevered,clamped-hinged,and simply supported conditions in this *** though some researchers used several schemes to overcome these forward problems of Euler-Bernoulli beams;however,an effective numerical algorithm to solve these inverse problems is still not *** cope with the homogeneous boundary conditions,initial data,and final time datum for each type of nonlinear beam by employing a variety of boundary shape *** unknown nonlinear large external force can be recuperated via back-substitution of the solution into the nonlinear Euler-Bernoulli beam equation when we acquire the solution by utilizing the boundary shape function scheme and deal with a smallscale linear system to gratify an additional right-side boundary *** the robustness and accuracy,we reveal that the current schemes are substantiated by comparing the recuperated numerical results of four instances to the exact forces,even though a large level of noise up to 50%is burdened with the overspecified *** current method can be employed in the online real-time computation of unknown force functions in space-time for varied boundary supports of the vibrating nonlinear beam.

关键词： Inverse problems nonlinear Euler-Bernoulli beams ill-posed problems nonlinear space-time dependent force boundary shape functions

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Efficient and simple synthesis of B_(2)O_(3)-Al_(2)O_(3)nanocomposites assisted by deep eutectic solvent for production of 5-hydroxymethylfurfural from glucose

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Nano Research 2025年第1期18卷 236-248页

作者： Yuchen Wang Kai Rong Shanlei chang Youxing Fang Shaojun Dong State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China College of Chemistry Jilin UniversityChangchun 130012China

The catalytic conversion of glucose to high valueadded platform chemical 5-hydroxymethylfurfural(HMF)is a promising biorefinery process,and alumina-boria catalysts are considered to be green and mild solid acid catalysts for this catalytic ***,compared to the common synthesis methods with complicated steps,we reported a simple and efficient strategy to prepare B_(2)O_(3)-Al_(2)O_(3)nanocomposites by calcining cost-effective glucose-urea deep eutectic solvent(DES)solution containing the *** prepared B_(2)O_(3)-Al_(2)O_(3)nanocomposites exhibited an open three-dimensional skeleton and two-dimensional porous lamellar substructure,endowing them with a high specific surface area(228.27 m2/g).The introduction of boron changed the ratios of different aluminum species(AlⅣ,AlⅤ,and AlⅥ)and borate species(BO3 and BO4),thus further affecting the acidity and the types of acid sites of the *** prepared B_(2)O_(3)-Al_(2)O_(3)bifunctional acid catalysts possessing abundant Lewis acid sites and adjustable Brønsted acid sites showed complete glucose conversion and 55.38%of HMF yield under the optimum *** study proposed a concise method to synthesize alumina-boria solid acid catalysts assisted by glucose-urea *** hope to extend the application and prospect of this efficient and simple synthesis strategy.

关键词： 5-hydroxymethylfurfural(HMF) deep eutectic solvent glucose alumina-boria acid catalyst

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Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi Yu Faith Teo En Ning chang Liu Yu-Chi Liu Tissue Engineering and Stem Cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

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Seasonal Prediction of Boreal Winter Rainfall over the Western Maritime Continent during ENSO

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Journal of Meteorological Research 2020年第2期34卷 294-303页

作者： chih-Pei chang Tim LI Song YANG Department of Meteorology Naval Postgraduate SchoolMontereyCA 93943USA Key Laboratory of Meteorological Disaster Ministry of Education(KLME)/Joint International Research Laboratory of Climate and Environmental Change(ILCEC)/Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)Nanjing University of Information Science&TechnologyNanjing 210044China Department of Atmospheric Sciences School of Ocean and Earth Science and TechnologyUniversity of HawaiiHonoluluHI 96822USA School of Atmospheric Sciences Sun Yat-sen UniversityGuangzhou 510275China

Since the beginning of the Association of Southeast Asian Nations Climate Outlook Forum(ASEANCOF)in 2013,the most difficult challenge has been the rainfall forecast in boreal *** is the Maritime Continent monsoon season during which rainfall reaches maximum in the annual *** forecast difficulty arises in spite of the general notion that seasonal predictability of the Maritime Continent rainfall may be higher than most places because of the strong and robust influences of *** lower predictability is consistent with the lower correlation between ENSO and western Maritime Continent rainfall that reaches minimum during the boreal winter *** theories have been proposed to explain this low *** this paper,we review the research on ENSO–Maritime Continent rainfall relationship and show that the main cause of the forecast difficulty is the wind–terrain interaction involving the Sumatran and Malay Peninsula mountains,rather than the effect of sea surface temperature(SST).The wind–terrain interaction due to the low-level regional scale anomalous horizontal circulation offsets the anomalous Walker circulation during both El Ni?o and La Ni?*** net result of these two opposing responses to ENSO is a lower local *** propose to call this low-predictability region the WIMP(Western Indonesia–Malay Peninsula)region both for its geographical location and its special characteristic of causing difficulties for forecasters to make a confident forecast for the boreal *** result suggests that climate models lack skills in forecasting rainfall in this region because their predictability depends strongly on SST.

关键词： seasonal forecast Maritime Continent ENSO monsoon rainfall wind-terrain interaction

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Solitary concomitant endocrine tumor and ductal adenocarcinoma of pancreas

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World Journal of Gastroenterology 2010年第21期16卷 2692-2697页

作者： Shih-Tang Yan chang-Kuo Wei chih-Wen Lin chih-En Tseng Department of Endocrinology and Metabolism Buddhist Dalin Tzu Chi General HospitalChiayi 622TaiwanChina Department of General Surgery Buddhist Dalin Tzu Chi General HospitalChiayi 622TaiwanChina Department of Medical Imaging Buddhist Dalin Tzu Chi General HospitalChiayi 622TaiwanChina Department of Anatomic Pathology Buddhist Dalin Tzu Chi General HospitalChiayi 622TaiwanChina School of Medicine Tzu Chi UniversityHualien 97004TaiwanChina

Pancreatic tumors with combined exocrine and endocrine features are *** reported cases are classified as mixed exocrine and endocrine carcinoma of the *** report the first case of solitary concomitant endocrine tumor and ductal adenocarcinoma of the pancreas.A 58-year-old patient was admitted for uncontrolled diabetes mellitus and body weight *** tumor was fortuitously discovered in the pancreatic tail after a tumor survey ***,the solitary tumor had a central fibrous band that clearly divided it into two *** microscopic examination,the tumor contained both endocrine and exocrine components distinctly separated by the central fibrous *** exocrine part showed a poorly-differentiated *** endocrine part was strongly immunoreactive to chromogranin,synaptophysin and *** reviewed the literature on pancreatic tumors with combined exocrine and endocrine features.A simple classification for this group of neoplasms is suggested,including five types:amphicrine,mixed,collision,solitary concomitant and multiple concomitant.

关键词： Pancreas Concomitant tumor Collision tumor Mixed tumor Glucagonoma

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Synergistic effect of fatty liver and smoking on metabolic syndrome

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World Journal of Gastroenterology 2009年第42期15卷 5334-5339页

作者： po-Hsin Chiang Tsui-Yen chang Jong-Dar Chen Department of Family Medicine Shin Kong Wu Ho-Su Memorial Hospital#95 Wen Chang RoadShih LinTaipei 111TaiwanChina School of Medicine Fu Jen Catholic University#510 Chung Cheng RoadHsinchuangTaipei 242TaiwanChina

AIM:To investigate the association of fatty liver and smoking on metabolic syndrome and its ***:This cross-sectional study enrolled participants who attended annual health screening at Shin Kong Wu Ho-Su Memorial Hospital from January to December 2005.A total of 3455(1981 men and 1474 women) subjects were included in final *** liver was diagnosed using abdominal ultrasonography by trained *** modified National Cholesterol Education Program Adult Treatment Panel Ⅲ was used to define metabolic *** associations between smoking,fatty liver and metabolic syndrome were analyzed using multiple logistic ***:Subjects with fatty liver,and who smoked tobacco,had the highest odds ratios(ORs) for high waist circumference [OR,4.5(95% CI:3.3-6.1) ,P poprotein cholesterol(HDL-C) [OR,8.3(95% CI:6.1-11.3) ,P ponents,especially for hypertriglyceridemia and low serum HDL-C.

关键词： Smoking Fatty liver Synergistic effect Metabolic syndrome

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Code Transform Model Producing High-Performance Program

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Computer Modeling in Engineering & Sciences 2021年第10期129卷 253-277页

作者： Bao Rong chang Hsiu-Fen Tsai po-Wen Su Department of Computer Science and Information Engineering National University of KaohsiungKaohsiungTaiwan Department of Fragrance and Cosmetic Science Kaohsiung Medical UniversityKaohsiungTaiwan

This paper introduces a novel transform method to produce the newly generated programs through code transform model called the second generation of Generative Pre-trained Transformer(GPT-2)reasonably,improving the program execution performance ***,a theoretical estimation in statistics has given the minimum number of generated programs as required,which guarantees to find the best one within *** proposed approach can help the voice assistant machine resolve the problem of inefficient execution of application *** addition to GPT-2,this study develops the variational Simhash algorithm to check the code similarity between sample program and newly generated program,and conceives the piecewise longest common subsequence algorithm to examine the execution’s conformity from the two programs mentioned *** code similarity check deducts the redundant generated programs,and the output conformity check finds the best-performing generative *** addition to texts,the proposed approach can also prove the other media,including images,sounds,and *** a result,the newly generated program outperforms the sample program significantly because the number of code lines reduces 27.21%,and the program execution time shortens 24.62%.

关键词： Newly generated programs GPT-2 predetermined generative programs variational Simhash algorithm piecewise longest common subsequence

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