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Ensemble Model for Spindle Thermal Displacement Prediction of Machine Tools

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Computer Modeling in Engineering & Sciences 2023年第10期137卷 319-343页

作者： Ping-Huan Kuo Ssu-Chi Chen Chia-Ho Lee po-chien luan Her-Terng Yau Department of Mechanical Engineering National Chung Cheng UniversityChiayi62102Taiwan Advanced Institute of Manufacturing with High-Tech Innovations(AIM-HI) National Chung Cheng UniversityChiayi62102Taiwan

Numerous factors affect the increased temperature of a machine tool, including prolonged and high-intensity usage,tool-workpiece interaction, mechanical friction, and elevated ambient temperatures, among others. Consequently,spindle thermal displacement occurs, and machining precision suffers. To prevent the errors caused by thetemperature rise of the Spindle fromaffecting the accuracy during themachining process, typically, the factory willwarm up themachine before themanufacturing ***, if there is noway to understand the tool spindle’sthermal deformation, the machining quality will be greatly affected. In order to solve the above problem, thisstudy aims to predict the thermal displacement of the machine tool by using intelligent algorithms. In the practicalapplication, only a few temperature sensors are used to input the information into the prediction model for realtimethermal displacement prediction. This approach has greatly improved the quality of tool ***,each algorithm has different performances in different environments. In this study, an ensemble model is used tointegrate Long Short-TermMemory (LSTM) with Support VectorMachine (SVM). The experimental results showthat the prediction performance of LSTM-SVM is higher than that of other machine learning algorithms.

关键词： Thermal displacement ensemble model LSTM milling machine spindle

Interaction of major facilitator superfamily domain containing 2A with the blood-brain barrier

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Neural Regeneration Research 2025年第8期20卷 2133-2152页

作者： Yilun Ma Taiwei Dong Fei luan Juanjuan Yang Feng Miao Peifeng Wei College of Pharmacy and First Clinical Medical College Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina National Drug Clinical Trial Agency The Second Affiliated Hospital of Shaanxi University of Chinese Medicine/Xixian New District Central HospitalXi′anShaanxi ProvinceChina

The functional and structural integrity of the blood-brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms underlying the formation and function of the blood-brain barrier remain poorly *** major facilitator superfamily domain containing 2A has been identified as a key regulator of blood-brain barrier *** plays a critical role in promoting and maintaining the formation and functional stability of the blood-brain barrier,in addition to the transport of lipids,such as docosahexaenoic acid,across the blood-brain ***,an increasing number of studies have suggested that major facilitator superfamily domain containing 2A is involved in the molecular mechanisms of blood-brain barrier dysfunction in a variety of neurological diseases;however,little is known regarding the mechanisms by which major facilitator superfamily domain containing 2A affects the blood-brain *** paper provides a comprehensive and systematic review of the close relationship between major facilitator superfamily domain containing 2A proteins and the blood-brain barrier,including their basic structures and functions,cross-linking between major facilitator superfamily domain containing 2A and the blood-brain barrier,and the in-depth studies on lipid transport and the regulation of blood-brain barrier *** comprehensive systematic review contributes to an in-depth understanding of the important role of major facilitator superfamily domain containing 2A proteins in maintaining the structure and function of the blood-brain barrier and the research progress to *** will not only help to elucidate the pathogenesis of neurological diseases,improve the accuracy of laboratory diagnosis,and optimize clinical treatment strategies,but it may also play an important role in prognostic *** addition,the effects of major facilitator superfamily domain containing 2A on blood-brain barrier lea

关键词： blood-brain barrier(BBB) caveolin-1 central nervous system docosahexaenoic acid endothelial cells lysophosphatidylcholine major facilitator superfamily domain containing 2A(MFSD2A) transcytosis

postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development

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Neural Regeneration Research 2025年第3期20卷 900-912页

作者： Baoqi Hu Rui Wang Hanyue Zhang Xiou Wang Sijia Zhou Bo Ma Yan luan Xin Wang Xinlin Chen Zhichao Zhang Qianyan Kang Department of Ophthalmology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Ophthalmology The First Affiliated Hospital of Northwest UniversityXi’anShaanxi ProvinceChina Institute of Neurobiology Xi’an Jiaotong University Health Science CenterXi’anShaanxi ProvinceChina

The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell ***,the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development ***,we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo *** this study,we showed that postnatal retinal explants undergo normal development,and exhibit a consistent structure and timeline with retinas in ***,we used SOX2 and PAX6 immunostaining to identify retinal progenitor *** then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin,***-67-and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis,and exhibited a high degree of similarity in abundance and distribution between ***,we used Ceh-10 homeodomain-containing homolog,glutamate-ammonia ligase(glutamine synthetase),neuronal nuclei,and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells,Müller glia,mature neurons,and microglia,*** timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant *** study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina *** findings confirm the accuracy and credibility of this model and support its use for long-term,systematic,and continuous observation.

关键词： bipolar cells differentiation in vivo microglia Müller glia organotypic retinal explant culture postnatal retina development proliferation retinal progenitor cells

Correlations of the expression of Cx43,SCFFBXW7,p-cyclin E1(Ser73),p-cyclin E1(Thr77)and p-cyclin E1(Thr395)in colon cancer tissues

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 207-213页

作者： Rong-Gang luan Ming-Da Liu Zi-Feng Deng Cong-Lan Lu Mei-Ling Yu Ming-Yu Zhang Rong Liu Ran An You-Liang Yao Dong-Bei Guo Yong-Xing Zhang Lei Zhao Department of Gastrointestinal Surgery Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics School of Public HealthXiamen UniversityXiamen 361102Fujian ProvinceChina Trauma Surgery Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina Department of Orthopaedics Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina

BACKGROUND Previous cellular studies have demonstrated that elevated expression of Cx43 promotes the degradation of cyclin E1 and inhibits cell proliferation through ***,reduced expression results in a loss of this capacity to facilitate cyclin E *** ubiquitination and degradation of cyclin E1 may be associated with phosphorylation at specific sites on the protein,with Cx43 potentially enhancing this process by facilitating the phosphorylation of these critical *** To investigate the correlation between expression of Cx43,SKP1/Cullin1/F-box(SCF)FBXW7,p-cyclin E1(ser73,thr77,thr395)and clinicopathological indexes in colon *** Expression levels of Cx43,SCFFBXW7,p-cyclin E1(ser73,thr77,thr395)in 38 clinical colon cancer samples were detected by immunohistochemistry and were analyzed by statistical methods to discuss their *** positive rate of Cx43,SCFFBXW7,p-cyclin E1(Ser73),p-cyclin E1(Thr77)and p-cyclin E1(Thr395)in detected samples were 76.32%,76.32%,65.79%,5.26%and 55.26%*** expressions of these proteins were not related to the tissue type,degree of tissue differentiation or lymph node ***43 and SCFFBXW7(r=0.749),p-cyclin E1(Ser73)(r=0.667)and p-cyclin E1(Thr395)(r=0.457),SCFFBXW7 and p-cyclin E1(Ser73)(r=0.703)and p-cyclin E1(Thr395)(0.415)were correlated in colon cancer(Ppositively correlated in colon *** Cx43 may facilitate the phosphorylation of cyclin E1 at the Ser73 and Thr195 sites through its interaction with SCFFBXW7,thereby influencing the ubiquitination and degradation of cyclin E1.

关键词： Colon cancer Cx43 SCFFBXW7 Phosphorylation of cyclin E1 Sites of cyclin E1 Correlation analysis

基于PLUS模型的典型农牧交错带土地利用驱动力分析与多情景模拟

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水土保持研究 2025年第1期32卷 368-378页

作者：张启扬刘仁志栾朝旭北京师范大学环境学院水环境模拟国家重点实验室

[目的]实现农牧交错带地区破碎化土地利用变化的精准预测，为农牧交错带土地利用预测与结构调整提供重要工具。[方法]研究针对性构建了农牧交错带土地利用模拟方法(APE-PLUS),引入土地扩张分析策略(LEAS)、基于多类型随机斑块种子的CA模... 详细信息

[目的]实现农牧交错带地区破碎化土地利用变化的精准预测，为农牧交错带土地利用预测与结构调整提供重要工具。[方法]研究针对性构建了农牧交错带土地利用模拟方法(APE-PLUS),引入土地扩张分析策略(LEAS)、基于多类型随机斑块种子的CA模型(CARS)、Markov模型和土地利用情景设计，解决农牧交错带土地利用模拟中斑块零散、景观破碎、变化机制复杂的问题。采用二调、三调土地利用数据，分析了2014—2020年土地利用变化及其驱动力，模拟了2032年科左后旗自然增长、生态优先、耕地保护和可持续发展情景下的土地利用格局。[结果](1)农牧交错带土地利用模拟方法(APE-PLUS)精度较高，Kappa系数为0.87,总体精度达到0.92;(2)科左后旗2014—2020年土地利用变化显著，全旗47.85%的土地类型发生改变，14.65%的土地由耕地转变为草地，DEM和水资源是这一时期土地利用变化的主要驱动力；(3) 2032年多情景预测中，可持续发展情景耕地面积增长1.31%,林地和草地分别减少了0.77%和1.72%,其他用地面积减小28.4%,相比于其他3种情景，土地利用数量结构与空间格局更合理。此情景有助于减缓耕地扩张趋势和草地缩减趋势，有效控制水土流失、土壤沙化问题，提高生态保护与经济发展的协调程度。[结论]农牧交错带土地利用模拟方法(APE-PLUS)对科左后旗的土地利用具有较高的模拟精度，可以对农牧交错带斑块级的土地利用变化进行高精度的预测。

关键词：土地利用变化农牧交错带 PLUS模型科尔沁左翼后旗驱动因子

Synergetic organocatalysis for stereoregular ring-opening polymerization of O-carboxyanhydrides to isotactic functionalized polyesters

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材料导报 2020年第12期34卷 12001-12002页

作者： luan Shifang State Key Laboratory of polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China

polyesters,such as polylactide(PLA),are a class of biodegra-dable and biocompatible polymers that have received increasing attention in biomedicine,agriculture,and commodity thermoplastics[1-2].However,the lack of pendant functionality of conventional polyesters makes it difficult to modify and modulate the physicochemical properties in subsequent applications[3-4].Since 2006[5],the ring-opening polymerization(ROP)of O-carbox-yanhydrides(OCAs),which can be readily synthesized from amino acid or hydroxyl acid precursors,has been recognized as a promising route to functionalized polyesters[3-4].However,due to the increased methine C-H acidity,significant racemization of the stereogenic center and decreased stereoregularity have been identified for most OCAs,for instance,ManOCA[6](OCA from mandelic acid)and SerOCA[7](OCA from serine),when using typical 4-(dimethylamino)pyridine(DMAP)as *** minimize epimerization,some classical metal-based catalysts of coordination polymerization have been introduced to mediate ROP of OCAs,furnishing isotactic polyesters[8].

关键词： polyester polymerization stereo

Plasmon-enhanced Performance of Dye-sensitized Solar Cells Based on Electrodeposited Ag Nanoparticles

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Journal of Materials Science & Technology 2014年第1期30卷 1-7页

作者： Xinning luan Ying Wang Department of Mechanical & Industrial Engineering Louisiana State University

In the present work, pulse current deposition is used to deposit evenly distributed and uniformly sized Ag nanoparticles onto a TiO2 nanotube array as photoelectrode in dye-sensitized solar cells （DSSCs）, and the size and amount of loading Ag nanoparticles are controlled by the pulse deposition time. Due to the enhanced light absorption and electron-hole separation caused by plasmon effect, DSSCs based on Ag-modified TiO2 nanotube arrays show higher energy conversion efficiencies than those based on bare nanotubes with the same tube length. Particularly, DSSC based on nanotubes modified using pulse deposition time 1 s/3 s delivers the highest energy conversion efficiency of 1.68% and the largest short-circuit current of 4.37 mA/ cm2, while DSSC consisting of bare nanotubes exhibits efficiency of 1.20% and short-circuit current of 2.27 mA/cm2, which represents a 40% enhancement of cell efficiency in DSSC based on Ag-modified Ti02 nanotubes. It is also noted that overly long pulse deposition time will not further increase DSSC efficiency due to agglomeration of Ag particles. For example, when the pulse deposition time is increased to 2 s/6 s, DSSC based on Ag-modified nanotubes exhibits a lower efficiency of 1.42%. Moreover, high-concentration TiCI4 treatment on TiO2 nanotube arrays can further increase the energy conversion efficiencies to 3.82% and 2.61% for DSSC based on Ag-modified TiO2 nanotubes and DSSC based on bare TiO2 nanotubes, respectively, by significantly creating more surface area for dye loading.

关键词： TiO2 nanotube Dye-sensitized solar cell Pulse current deposition Ag nanoparticle TiCI4 treatment

Design of performance robustness for uncertain nonlinear time-delay systems via neural network

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Journal of Systems Engineering and Electronics 2007年第4期18卷 852-857,884页

作者： luan Xiaoli Liu Fei Inst. of Automations Southern Yangtze Univ. Wuxi 214122 P. R. China

Performance robustness problems via the state feedback controller are investigated for a class of uncertain nonlinear systems with time-delay in both state and control, in which the neural networks are used to model the nonlinearities. By using an appropriate uncertainty description and the linear difference inclusion technique, sufficient conditions for existence of such controller are derived based on the linear matrix inequalities （LMIs）. Using solutions of LMIs, a state feedback control law is proposed to stabilize the perturbed system and guarantee an upper bound of system performance, which is applicable to arbitrary time-delays.

关键词： nonlinear system time-delay uncertainties neural network linear matrix inequality

Thermal Annealing and Graphene Modification of Exfoliated Hydrogen Titanate Nanosheets for Enhanced Lithium-ion Intercalation Properties

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Journal of Materials Science & Technology 2014年第9期30卷 839-846页

作者： Xinning luan Ying Wang Department of Mechanical and Industrial Engineering Louisiana State UniversityBaton Rouge LA 70803 USA

Hydrogen titanate has been considered as a promising lithium intercalation material due to its unique layered structure. In the present work, we fabricate 2D graphene/hydrogen titanate hybrid nanosheets for application as anode materials in lithium-ion batteries. H2Ti307 nanosheets are synthesized by exfoliation of a layered precursor via interacting bulky tetrabutylammonium （TBA＋） cations, followed by ion exchange with Na＋ ions and washing with water. The as-prepared hydrogen titanate nanosheets are well-dispersed exhibiting ultra-thin thickness with a lateral size up to a few micrometers. The sample is then annealed at 450, 650 Rnd 850 ℃, to optimize its Li＋-intercalation property. Heating at 450 ℃ leads to well-crystallized hydrogen titanate with a trace amount of TiO2. Heating at 650 and 850 ℃ results in mixed sodium titanates, since some sodium ions in the interlayer structure cannot be washed away and become chemically bonded to [TiO6] octahedra at high temperatures. Electrochemical properties of all the four samples are then evaluated by charged/discharged for 100 electrochemical cycles at 0.01-2.5 V vs. Li＋/Li at a specific current of 170 mA g-1. The unannealed hydrogen titanate delivers the highest initial discharge capacity of 130.5 mA h g-l, higher than 124.6 mA h g-1 from hydrogen titanate annealed at 450 ℃, as well as 101.3 and 63.8 mA h g-1 from hydrogen titanate annealed at 650 and 850℃, respectively, due to the high surface area from well-dispersed unannealed nanosheets. However, after 100 electrochemical cycles, well-crystallized hydrogen titanate annealed at 450 ℃ retain the highest charge capacity of 115.2 mA h g-1, corresponding to a capacity retention of 92.5%, while unannealed hydrogen titanate exhibits a final capacity of 72.1 mA h g-1 and a capacity retention of only 55.2%. To further improve energy density of lithium-ion battery, graphene/hydrogen titanate hybrid nanosheets are fabricated by adding graphene nanosheets into hydrogen titanates

关键词： Hydrogen titanate Sodium titanate Graphene nanosheets Exfoliation process Lithium-ion battery