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Polymeric biomaterials-based tissue engineering for wound healing: a systemic review

Burns & Trauma 2023年第1期11卷 122-145页

作者： Pratik Das Suvendu Manna Shivam Roy Samit K.Nandi piyali basak School of Bioscience and Engineering Jadavpur University188Raja Subodh Chandra Mallick RdJadavpurKolkata 700032West BengalIndia Sustainability Cluster University of Petroleum and Energy StudiesDehradun 248007UttarakhandIndia Department of Veterinary Surgery and Radiology West Bengal University of Animal and Fishery SciencesBelgachiaKolkata 700037West BengalIndia

Background:Biomaterials are vital products used in clinical sectors as alternatives to several biological macromolecules for tissue engineering techniques owing to their numerous beneficial properties,including wound *** healing pattern generally depends upon the type of wounds,and restoration of the skin on damaged areas is greatly dependent on the depth and severity of the *** rate of wound healing relies on the type of biomaterials being incorporated for the fabrication of skin substitutes and their stability in in vivo *** this review,a systematic literature search was performed on several databases to identify the most frequently used biomaterials for the development of successful wound healing agents against skin damage,along with their mechanisms of ***:The relevant research articles of the last 5 years were identified,analysed and reviewed in this *** meta-analysis was carried out using PRISMA and the search was conducted in major scientific *** research of the most recent 5 years,from 2017-2021 was taken into *** collected research papers were inspected thoroughly for further *** advances in the utilization of natural and synthetic biomaterials(alone/in combination)to speed up the regeneration rate of injured cells in skin wounds were ***,23 papers were critically reviewed and ***:In total,2022 scholarly articles were retrieved from databases utilizing the aforementioned input *** eliminating duplicates and articles published before 2017,∼520 articles remained that were relevant to the topic at hand(biomaterials for wound healing)and could be evaluated for *** different procedures,23 publications were selected as best fitting for data *** Reporting Items for Systematic Reviews and Meta-Analyses for this review illustrates the selection criteria,such as exclusion and inclusion *** 23 recent publications

关键词： Wound healing Biomaterials Tissue engineering Skin regeneration Polymers

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