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基于误差扩散的计算全息显示方法

光学学报 2024年第8期44卷 27-36页

作者：魏平平韩超安徽工程大学电气工程学院安徽芜湖241000 安徽工程大学高端装备先进感知与智能控制教育部重点实验室安徽芜湖241000

以双向误差扩散算法为基础,通过分析图像振幅分布与生成全息图的关系,建立了全息图误差补偿模型,提出了一种新的纯相位全息图生成方法。首先通过误差扩散模型,计算出复振幅全息图与振幅置1的纯相位全息图的误差,通过对该误差进行误差扩... 详细信息

以双向误差扩散算法为基础,通过分析图像振幅分布与生成全息图的关系,建立了全息图误差补偿模型,提出了一种新的纯相位全息图生成方法。首先通过误差扩散模型,计算出复振幅全息图与振幅置1的纯相位全息图的误差,通过对该误差进行误差扩散生成新的纯相位全息图。利用新的纯相位全息图与复振幅全息图计算新的误差,进行第二次的误差扩散,得到最终的纯相位全息图。采用定性和定量的指标来评价仿真成像质量,仿真及光学实验结果表明,改进后的方法能够有效提升再现像的质量,为纯相位全息图制作提供一种新的方法。

关键词：全息全息显示误差扩散纯相位全息图

Tunable nano-engineered anisotropic surface for enhanced mechanotransduction and soft-tissue integration

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Nano Research 2023年第5期16卷 7293-7303页

作者： pingping han Tianqi Guo Anjana Jayasree Guillermo A.Gomez Karan Gulati Sašo Ivanovski The University of Queensland School of DentistryEpigenetics nanodiagnostic and therapeutic groupCenter for Oral-facial RegenerationRehabilitation and Reconstruction(COR3)BrisbaneQueensland 4006Australia The University of Queensland School of DentistryBrisbaneQueensland 4006Australia The University of Queensland School of DentistryGroup for Anodized Therapies for OsseointegrationRegeneration and StimulationCenter for Oral-facial RegenerationRehabilitation and Reconstruction(COR3)BrisbaneQueensland 4006Australia Centre for Cancer Biology South Australia Pathology and the University of South AustraliaAdelaideSouth Australia 5001Australia

Electrochemically engineered titania(TiO_(2))nanopores enable tailored cellular function;however,the cellular mechanosensing mechanisms dictating the cell response and soft tissue integration are yet to be elucidated.Here,we report the fabrication of anisotropic TiO_(2)nanopores with diameters of 46 and 66 nm on microrough titanium(Ti)via electrochemical anodization,towards short-and long-term guidance of human primary gingival fibroblasts(hGFs).Cells on tissue culture plates and bare Ti substrates were used as controls.Notably,we show that nanopores with a diameter of 66 nm induced more mature focal adhesions of vinculin and paxillin at the membrane,encouraged the development of actin fibers at focal adhesion sites,led to elongated cell and nuclear shape.These topographical-driven changes were attributed to the Ras-related C3 botulinum toxin substrate 1(Rac 1)GTPase pathway and nuclear localisation of LAMIN A/C and yes-associated protein(YAP)and associated with increased ligament differentiation with elevated expression of the ligament marker Mohawk homeobox(MKX).Study findings reveal that minor tuning of nanopore diameter is a powerful tool to explore intracellular and nuclear mechanotransduction and gain insight into the relationships between nanomaterials and mechanoresponsive cellular elements.

关键词： titanium nanopores nanotopography fibroblast mechanosensing mechanotransduction ligament differentiation

Facilitation of cascade biocatalysis by artificial multi-enzyme complexes——A review

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Chinese Journal of Chemical Engineering 2020年第11期28卷 2799-2809页

作者： Xinlei Wei pingping han Chun You Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjin 300308China

Multi-enzyme complexes are the results of natural evolution to facilitate cascade biocatalysis.Through enzyme colocalization within a complex,the transfer efficiency of reaction intermediates between adjacent cascade enzymes can be promoted,resulting in enhanced overall reaction efficiency.Inspired by nature,a variety of approaches have been developed for the assembly of artificial multi-enzyme complexes with different spatial organizations,aiming at improving the catalytic efficiency of enzyme cascade.A recent trend of this research area is the creation of enzyme complexes with a controllable spatial organization which helps with the mechanistic studies and bears the potential to further increase metabolic productivity.In this review,we summarize versatile strategies for the assembly of artificial multi-enzyme complexes,followed by an inspection of the mechanistic studies of artificial multi-enzyme complexes for their enhancement of catalytic efficiency.Furthermore,we provide some highlighted in vivo,ex vivo,and in vitro examples that demonstrate the ability of artificial multi-enzyme complexes for enhancing the overall production efficiency of value-added compounds.Recent research progress has revealed the great biotechnological potential of artificial multi-enzyme complexes as a powerful tool for biomanufacturing.

关键词： Enzyme Biocatalysis Cascade reaction scaffold substrate channeling synthetic biology

An in vitro synthetic biology platform for emerging industrial biomanufacturing:Bottom-up pathway design

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Synthetic and Systems Biotechnology 2018年第3期3卷 186-195页

作者： Ting Shi pingping han Chun You Yi-Heng P.Job Zhang Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences32 West 7th AvenueTianjin Airport Economic AreaTianjin300308China

Although most in vitro(cell-free)synthetic biology projects are usually used for the purposes of fundamental research or the formation of high-value products,in vitro synthetic biology platform,which can implement complicated biochemical reactions by the in vitro assembly of numerous enzymes and coenzymes,has been proposed for low-cost biomanufacturing of bioenergy,food,biochemicals,and nutraceuticals.In addition to the most important advantage-high product yield,in vitro synthetic biology platform features several other biomanufacturing advantages,such as fast reaction rate,easy product separation,open process control,broad reaction condition,tolerance to toxic substrates or products,and so on.In this article,we present the basic bottom-up design principles of in vitro synthetic pathway from basic building blocks-BioBricks(thermoenzymes and/or immobilized enzymes)to building modules(e.g.,enzyme complexes or multiple enzymes as a module)with specific functions.With development in thermostable building blocks-BioBricks and modules,the in vitro synthetic biology platform would open a new biomanufacturing age for the cost-competitive production of biocommodities.

关键词： Biomanufacturing Coenzyme regeneration Pathway design In vitro synthetic biology

顾客如何看待企业雇佣残障人士?顾客对社会企业的雇佣归因、顾客满意度与推荐意愿的关系研究

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中国人力资源开发 2024年第2期41卷 21-32页

作者：白婧韩佳宁富萍萍宁波诺丁汉大学商学院浙江宁波315100

社会企业雇佣心智障碍者是其履行企业社会责任(CSR)的重要体现之一。本研究以在社会企业“喜憨儿”洗车行中接受过心智障碍员工服务的307位顾客为调研对象,调查了顾客对于社会企业雇佣心智障碍者的动机归因,以及这些归因如何影响顾客对... 详细信息

社会企业雇佣心智障碍者是其履行企业社会责任(CSR)的重要体现之一。本研究以在社会企业“喜憨儿”洗车行中接受过心智障碍员工服务的307位顾客为调研对象,调查了顾客对于社会企业雇佣心智障碍者的动机归因,以及这些归因如何影响顾客对于企业的满意度及推荐意愿。研究结果表明顾客对于雇佣了心智障碍者的社会企业的雇佣行为的内部归因正向影响顾客满意度。顾客对于企业雇佣行为的外部归因负向影响顾客满意度,并且顾客满意度在雇佣归因与推荐意愿中起到了中介作用。本研究拓展了归因理论在企业雇佣心智障碍者这一CSR实践方面的应用,并探究了顾客对于社会企业雇佣行为的内外部归因对其态度所产生的不同影响,从而同时丰富了残障人士就业领域和企业社会责任方向的文献。

关键词：心智障碍者就业雇佣归因顾客满意度推荐意愿社会企业

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考虑CVT输出特性的换流变剩磁测算方法

电力自动化设备 2024年第6期44卷 90-95,109页

作者：韩平平王焱陈宇翔陈忠胡迪合肥工业大学新能源利用与节能安徽省重点实验室安徽合肥230009 国网安徽省电力有限公司电力科学研究院安徽合肥230061

特高压换流变空载合闸时,其剩磁会改变铁心磁通的大小和方向,极易造成严重的励磁涌流,导致换流变无法正常投入运行。针对换流变剩磁测算,分析电容式电压互感器(CVT)输出数据存在误差是由系统频率变化引起的,根据误差式进行校正并基于电... 详细信息

特高压换流变空载合闸时,其剩磁会改变铁心磁通的大小和方向,极易造成严重的励磁涌流,导致换流变无法正常投入运行。针对换流变剩磁测算,分析电容式电压互感器(CVT)输出数据存在误差是由系统频率变化引起的,根据误差式进行校正并基于电压积分法给出考虑CVT输出特性的换流变剩磁测算方法。在PSCAD/EMTDC中搭建相关仿真模型,对Y、D桥换流变的电压正向、负向峰值处分别进行分闸实验,并根据所提测算方法确定换流变剩磁。利用校正前、校正后以及监测的换流变剩磁完成选相合闸对比实验,实验结果表明所提方法能够有效测算换流变剩磁,为励磁涌流抑制手段提供参考依据。

关键词：换流变剩磁 CVT 电压积分法选相合闸

Improved image resolution on thoracic carcinomas by quantitative 18F-FDG coincidence SPECT/CT in comparison to 18F-FDG PET/CT

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The Journal of Biomedical Research 2020年第4期34卷 309-317页

作者： Yuming Zheng Chaoling Jin Huijuan Cui Haojie Dai Jue Yan pingping han Bailing Hsu Nuclear Medicine Department China-Japan Friendship HospitalBeijing 100029China Oncology of Integrative Medicine Department China-Japan Friendship HospitalBeijing 100029China Nuclear Medicine Department Danli HospitalBeijing 100073China Nuclear Science and Engineering Institute University of Missouri-ColumbiaColumbiaMO 65201USA.

Currently,18F-FDG coincidence SPECT(Co-SPECT)/CT scan still serves as an important tool for diagnosis,staging,and evaluation of cancer treatment in developing countries.We implemented full physical corrections(FPC) to Co-SPECT(quantitative Co-SPECT) to improve the image resolution and contrast along with the capability for image quantitation.FPC included attenuation,scatter,resolution recovery,and noise reduction.A standard NEMA phantom filled with 10:1 F-18 activity concentration ratio in spheres and background was utilized to evaluate image performance.Subsequently,15 patients with histologically confirmed thoracic carcinomas were included to undergo a 18 F-FDG Co-SPECT/CT scan followed by a 18 F-FDG PET/CT scan.Functional parameters as SUVmax,SUVmean,SULpeak,and MTV from both quantitative Co-SPECT and PET were analyzed.Image resolution of Co-SPECT for NEMA phantom was improved to reveal the smallest sphere from a diameter of 28 mm to 22 mm(17 mm for PET).The image contrast was enhanced from 1.7 to 6.32(6.69 for PET) with slightly degraded uniformity in background(3.1% vs.6.7%)(5.6% for PET).Patients’ SUVmax,SUVmean,SULpeak,and MTV measured from quantitative Co-SPECT were overall highly correlated with those from PET(r=0.82-0.88).Adjustment of the threshold of SUVmax and SUV to determine SUVmean and MTV did not further change the correlations with PET(r=0.81-0.88).Adding full physical corrections to Co-SPECT images can significantly improve image resolution and contrast to reveal smaller tumor lesions along with the capability to quantify functional parameters like PET/CT.

关键词： 18F-FDG coincidence SPECT/CT full physical corrections thoracic carcinomas image quantitation

我国设施生态农业主要模式及配套技术的研究与实践

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浙江大学学报（农业与生命科学版） 2024年第2期50卷 149-160页

作者：李萍萍韩建刚陈欣高丽红南京林业大学生态与环境学院江苏南京212013 浙江大学生命科学学院浙江杭州310058 中国农业大学园艺学院北京100193

设施生态农业是指在设施种植和设施养殖中采用清洁、绿色、健康生产方式,以提高资源利用效率、农产品产量与质量、环境效益为目标的生态农业模式。2002年农业部重点推广的设施生态农业模式主要有两大类:一类是种养沼三结合的“四位一体... 详细信息

设施生态农业是指在设施种植和设施养殖中采用清洁、绿色、健康生产方式,以提高资源利用效率、农产品产量与质量、环境效益为目标的生态农业模式。2002年农业部重点推广的设施生态农业模式主要有两大类:一类是种养沼三结合的“四位一体”生态模式,从最初以农户为单位的单体日光温室到以村庄为单位的种养结合生态温室群模式,拓展到在一个大区域内将大型猪场的粪污进行工业化沼气并网发电,沼液通过管道输送到农田来减少化肥施用和改良土壤的宏观生态农业模式,相关的结构配置、配套的种养殖技术和装备也在不断研发和提升中。另一类是采用综合性生态农业技术的设施生态农业模式,包括:采用各类立体/垂直栽培技术提高土地资源利用率;通过各种轮作栽培技术减少设施蔬菜土壤连作障碍和降低农药使用量;采用土壤健康栽培技术,通过有机肥的合理施用改善土壤性状;采用有机基质栽培技术,用农林废弃物发酵后的物料作为栽培基质为作物提供养分;采用覆盖防虫网、色板诱杀、灯光诱杀、高温封棚、蒸气消毒、有色膜覆盖土壤、天敌昆虫生物防治等病虫草害生态防治技术来减少有害生物发生。期望通过相关配套装备技术的进一步研发提高设施生态农业的信息化、自动化水平,实现设施农业的可持续发展。

关键词：设施生态农业 “四位一体”生态模式种养沼结合立体栽培轮作栽培有机基质栽培生态防治

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基于系统聚类法的含新能源电力系统分区策略

电力系统及其自动化学报 2024年第5期36卷 114-120页

作者：韩平平郭佳林董玮王正风安徽省新能源利用与节能省级实验室(合肥工业大学) 合肥230009 新能源与储能运行控制国家重点实验室(中国电力科学研究院) 北京100192 国网安徽省电力有限公司合肥230062

为实现含新能源电力系统的惯量分布特性的有效评估,提出一种基于系统聚类法的含新能源电力系统分区策略。首先分析新能源机组惯量与同步机组惯量之间的差异;其次构建节点惯量响应模型,分析节点惯量相关因素的特性;然后通过主成分分析对... 详细信息

为实现含新能源电力系统的惯量分布特性的有效评估,提出一种基于系统聚类法的含新能源电力系统分区策略。首先分析新能源机组惯量与同步机组惯量之间的差异;其次构建节点惯量响应模型,分析节点惯量相关因素的特性;然后通过主成分分析对影响节点惯量的主导变量进行降维,将降维后的变量应用系统聚类法对节点进行聚类分区;最后通过系统辨识得到区域惯量,评判出整个系统惯量的空间分布。在仿真软件中搭建改进的IEEE 10机39节点模型验证了分区策略的合理性。

关键词：系统聚类法新能源电力系统惯量分区系统辨识