检索结果-南通市图书馆

Nano Research 2025年第1期18卷 208-216页

作者： Wenjie Wu Haoyang Zhou ying Liu Yifei Pan Qingqing Chen Yu zhang Junjie Mao Wenjie Ma ping Yu Beijing National Laboratory for Molecular Sciences Key Laboratory of Analytical Chemistry for Living BiosystemsInstitute of ChemistryChinese Academy of Sciences(CAS)Beijing 100190China College of Chemistry and Materials Science Anhui Normal UniversityWuhu 241002China University of Chinese Academy of Sciences Beijing 100049China

The electrochemical conversion of carbon dioxide(CO_(2))into chemical fuels represents a promising approach for addressing global carbon balance ***,this process is hindered by the kinetic limitations of anodic reactions,usually the oxygen evolution reaction,resulting in less efficient production of high value-added ***,we report an integrated electrocatalytic system that couples CO_(2)reduction reaction(CO_(2)RR)with urea oxidation reaction(UOR)using a bifunctional electrocatalyst with atomically dispersed dual-metal CuNi sites anchored on bamboo-like nitrogen-doped carbon nanotubes(CuNi-CNT),which were synthesized through a one-step pyrolysis *** bifunctional CuNi-CNT catalyst exhibits a near 100%CO Faraday efficiency for CO_(2)RR over a wide potential range and outstanding UOR performance with a negatively shifted potential of 210 mV at 10 mA·cm^(-2).In addition,we assemble a two-electrode electrolyzer using bifunctional CuNi-CNT-modified carbon fiber paper electrodes as both cathode and anode,capable of operating at a remarkably low cell voltage of 1.81 V at 10 mA·cm-2,significantly lower than conventional *** study provides a novel avenue to achieving an efficient carbon cycle with reduced electric power consumption.

关键词： electrochemical conversion bimetallic site catalyst bifunctional electrocatalyst carbon dioxide reduction urea oxidation

鼻饲肠内营养混悬液+微生态制剂对老年患者腹泻的预防作用

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界华人消化杂志 2016年第34期24卷 4604-4607页

作者：张颖萍秦龙金一颜卫峰徐庆杰陈喆北京市海淀医院重症医学科北京市100080

目的探讨微生态调节剂与谷氨酰胺联合应用对老年患者肠内营养相关性腹泻的预防效果.方法选取2014-02/2016-03在北京市海淀医院接受肠内营养治疗老年患者82例为研究对象,采用随机数字表法分为治疗组与对照组,对照组患者给予鼻饲肠内营养... 详细信息

目的探讨微生态调节剂与谷氨酰胺联合应用对老年患者肠内营养相关性腹泻的预防效果.方法选取2014-02/2016-03在北京市海淀医院接受肠内营养治疗老年患者82例为研究对象,采用随机数字表法分为治疗组与对照组,对照组患者给予鼻饲肠内营养混悬液和微生态制剂,治疗组在对照组的基础上加用谷氨酰胺,对比两组患者腹泻发生率、鼻饲前及鼻饲第8天体液免疫功能指标及肠内营养液达到目标供给量时间.结果与对照组对比,治疗组患者腹泻率显著降低,差异有统计学意义(P0.05),与鼻饲前对比,治疗组患者的免疫球蛋白A(immunoglobulin A,IgA)水平显著升高,且鼻饲后显著高于对照组患者的IgA水平,差异有统计学意义(P<0.05);与对照组对比,治疗组患者肠内营养达到目标供给量所需时间显著缩短,差异有统计学意义(P<0.05).结论微生态调节剂与谷氨酰胺联合应用有助于降低老年患者肠内营养相关性腹泻的发生率,改善老年患者免疫功能,值得临床推广应用.

关键词：微生态调节剂谷氨酰胺肠内营养腹泻

Subretinal fibrosis secondary to neovascular age-related macular degeneration:mechanisms and potential therapeutic targets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 378-393页

作者： Jingxiang zhang Xia Sheng Quanju Ding Yujun Wang Jiwei Zhao Jingfa zhang Department of Ophthalmology People’s Hospital of Huangdao DistrictQingdaoShandong ProvinceChina Department of Urology People’s Hospital of Huangdao DistrictQingdaoShandong ProvinceChina Department of Ophthalmology Shanghai General Hospital(Shanghai First People’s Hospital)Shanghai Jiao Tong University School of MedicineShanghaiChina National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghaiChina

Subretinal fibrosis is the end-stage sequelae of neovascular age-related macular *** causes local damage to photoreceptors,retinal pigment epithelium,and choroidal vessels,which leads to permanent central vision loss of patients with neovascular age-related macular *** pathogenesis of subretinal fibrosis is complex,and the underlying mechanisms are largely ***,there are no effective treatment options.A thorough understanding of the pathogenesis of subretinal fibrosis and its related mechanisms is important to elucidate its complications and explore potential *** current article reviews several aspects of subretinal fibrosis,including the current understanding on the relationship between neovascular age-related macular degeneration and subretinal fibrosis;multimodal imaging techniques for subretinal fibrosis;animal models for studying subretinal fibrosis;cellular and non-cellular constituents of subretinal fibrosis;pathophysiological mechanisms involved in subretinal fibrosis,such as aging,infiltration of macrophages,different sources of mesenchymal transition to myofibroblast,and activation of complement system and immune cells;and several key molecules and signaling pathways participating in the pathogenesis of subretinal fibrosis,such as vascular endothelial growth factor,connective tissue growth factor,fibroblast growth factor 2,platelet-derived growth factor and platelet-derived growth factor receptor-β,transforming growth factor-βsignaling pathway,Wnt signaling pathway,and the axis of heat shock protein 70-Toll-like receptors 2/*** review will improve the understanding of the pathogenesis of subretinal fibrosis,allow the discovery of molecular targets,and explore potential treatments for the management of subretinal fibrosis.

关键词： choroidal neovascularization epithelial-mesenchymal transition mesenchymal transition myofibroblast neovascular age-related macular degeneration submacular fibrosis subretinal fibrosis therapeutic targets transforming growth factor-β vascular endothelial growth factor

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2520-2537页

作者： Chonglin Su Taiqi Huang Meiyu zhang Yanyu zhang Yan Zeng Xingxing Chen Brain Science and Advanced Technology Institute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental *** the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an important component of the hypothalamicpituitary-a d renal axis's negative feedback loop and plays a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences cognitive processes,including glutamate neurotransmission,calcium signaling,and the activation of brain-derived neurotrophic factor-mediated pathways,through a combination of genomic and non-genomic *** interactions within the central nervous system can alter the expression and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal axis and stress-related cognitive *** appropriate level of glucocorticoid receptor expression can improve cognitive function,while excessive glucocorticoid receptors or long-term exposure to glucoco rticoids may lead to cognitive *** with cognitive impairment-associated diseases,such as Alzheimer's disease,aging,depression,Parkinson's disease,Huntington's disease,stroke,and addiction,often present with dysregulation of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor *** review provides a comprehensive overview of the functions of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal axis and cognitive *** emphasizes that appropriate glucocorticoid receptor signaling fa cilitates learning and memory,while its dysregulation can lead to cognitive *** provides clues about how glucocorticoid receptor signaling can be targeted to ove rcome cognitive disability-related disorders.

关键词： brain-derived neurotrophic factor calcium signaling glucocorticoid receptor glucocorticoid glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders neuroplasticity stress

Bending Stiffness of Concrete-Filled Steel Tube and Its Influence on Concrete Placement Timing of Composite Beam-String Structure

在线全文

学校读者我要写书评

暂无评论

Structural Durability & Health Monitoring 2025年第1期19卷 55-75页

作者： Zhenyu zhang Quan Jin Haitao zhang Zhao Liu Yuyang Wu Longfei zhang Renzhang Yan CCCC Third Highway Engineering Co. Ltd.Beijing101300China School of Civil Engineering Chongqing Jiaotong UniversityChongqing400074China

When the upper chord beam of the beam-string structure(BSS)is made of concrete-filled steel tube(CFST),its overall stiffness will change greatly with the construction of concrete placement,which will have an impact on the design of the tensioning plans and selection of control measures for the *** order to accurately obtain the bending stiffness of CFST beam and clarify its impact on the mechanical properties of composite BSS during construction,the influence of some factors such as height-width ratio,wall thickness of steel tube,elasticity modulus of concrete,and friction coefficient on the bending stiffness are analyzed parametrically by the numerical simulation technology based on an actual *** calculation formula of the equivalent bending stiffness of CFST is also established through mathematical statistical ***,the equivalent bending stiffness is introduced into the construction and use stages of the composite BSS,respectively,and the mechanical properties such as prestress-tensioning control value,structural deformation,and internal force of key members are comparatively analyzed when adopting two different construction ***,the optimal construction plan of concrete placement first and then prestress-tensioning is proposed.

关键词： Concrete panels freeze-thaw damage compression-shear crack tension-shear crack

Dielectric-ion-conductive ZnNb2O6 layer enabling rapid desolvation and diffusion for dendrite-free Zn metal batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 693-701页

作者： Haifeng Yang Jian Wang Panpan zhang Xiaomin Cheng Qinghua Guan Jing Dong Bixian Chen Lujie Jia Jing zhang Yongzheng zhang Yunjian Liu Hongzhen Lin School of Materials Science and Engineering Jiangsu University i-Lab & CAS Key Laboratory of Nanophotonic Materials and Devices Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Helmholtz Institute Ulm (HIU) Karlsruhe Institute of Technology (KIT) School of Materials Science and Engineering Xi'an University of Technology State Key Laboratory of Chemical Engineering East China University of Science and Technology

Rechargeable aqueous zinc-metal batteries （AZMBs） are promising candidates for large-scale energy storage systems due to their low cost and high ***,their performance and sustainability are significantly hindered by the sluggish desolvation kinetics at the electrode/electrolyte interface and the corresponding hydrogen evolution reaction where active water molecules tightly participate in the Zn（H2O）62+solvation ***,learnt from self-generated solid electrolyte interphase （SEI） in anodes,the dielectric but ion-conductive zinc niobate nanoparticles artificial layer is constructed on metallic Zn surface （ZNB@Zn）,acting as a rapid desolvation *** zincophilic and dielectric-conductive properties of ZNB layer accelerate interfacial desolvation/diffusion and suppress surface corrosion or dendrite formation,achieving uniform Zn plating/stripping behavior,as confirmed by electronic/optical microscopies and interface spectroscopical measurements together with theoretical ***,the as-prepared ZNB@Zn electrode exhibits excellent cycling stability of over 2000 h and robust reversibility （99.54%） even under high current density and depth of discharge ***,the assembled ZNB@Zn-based full cell displays high capacity-retention rate of 80.21%after 3000 cycles at 5 A g-1and outstanding rate performance up to 10 A *** large-areal pouch cell is stabilized for hundreds of cycles,highlighting the bright prospects of the dielectric but ion-conductive layer in further application of AZMBs.

关键词： Zn metal battery Dielectric artificial layer Rapid ion diffusion Zincophilic diffusion Active water inhibition

Preparation of Low Ratio Magnesium Ccement by Acid Leaching Treatment of Boron Mud

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 120-129页

作者： YANG Mei zhang Mingzhe CHEN Hao School of Materials Science and Engineering Shenyang Jianzhu UniversityShenyang 110168China School of Physical Science and Technology Shenyang Normal UniversityShenyang 110168China

The effects of liquid-solid ratio and reaction time on the leaching rate of magnesium at room temperature were investigated,as well as the effects of the molar ratio of MgO/MgCl_(2),the amount of water added,and the amount of acid-impregnated slag dosed on the compressive strength and water resistance of *** results showed that the magnesium element in the boron mud could be maximally leached under the conditions of 1:1 concentration of hydrochloric acid at room temperature,liquid-solid ratio of 2.5 mL·g^(-1),and reaction time of 5 h,and the main products were amorphous SiO_(2) as well as a small amount of magnesium olivine which had not been completely *** LR-MOC prepared using the acid-soaked mixture could reach a softening coefficient of 0.85 for 28 d of water immersion when the molar ratio of MgO/MgCl_(2) was 2.2,the amount of water added was 0 g,and the acid-soaked slag dosing was 40 wt%,which also led to an appreciable late-strength,with an increase of 19.4%in compressive strength at 28 d compared to that at 7 *** previous studies,LR-MOC prepared in this way has a final strength phase that is not the more easily hydrolysed 3-phase but the lath-like *** this phenomenon,we analyzed the mechanism and found that,during the acid leaching process,a part of amorphous SiO_(2) dissolved in the acid leaching solution formed a silica sol,in which Mg^(2+)played a bridging role to make the silica sol more *** the addition and hydrolysis of MgO,the silica sol gel coagulation slows down,providing a capping layer to inhibit the hydrolysis of the 5-phase crystals and providing some strength after *** amorphous SiO_(2) in the other part of the acid-impregnated slag generated M-S-H gel with Mg^(2+)and OH-,which synergised with the dense structure composed of interlocking crystals to improve the water resistance of LR-MOC.

关键词： boron mud magnesium chloride-oxygen cement acid immersion water resistance silica sol

Flexible Graphene Field‑Effect Transistors and Their Application in Flexible Biomedical Sensing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 252-313页

作者： Mingyuan Sun Shuai Wang Yanbo Liang Chao Wang Yunhong zhang Hong Liu Yu zhang Lin Han Institute of Marine Science and Technology Shandong UniversityQingdao 266237ShandongPeople’s Republic of China State Key Laboratory of Crystal Materials Shandong UniversityJinan 250100ShandongPeople’s Republic of China School of Integrated Circuits Shandong UniversityJinan 250100ShandongPeople’s Republic of China Shandong Engineering Research Center of Biomarker and Artificial Intelligence Application Jinan250100ShandongPeople’s Republic of China

Flexible electronics are transforming our lives by making daily activities more *** to this innovation are field-effect transistors(FETs),valued for their efficient signal processing,nanoscale fabrication,low-power consumption,fast response times,and ***,known for its exceptional mechanical properties,high electron mobility,and biocompatibility,is an ideal material for FET channels and *** combination of graphene and FETs has given rise to flexible graphene field-effect transistors(FGFETs),driving significant advances in flexible electronics and sparked a strong interest in flexible biomedical ***,we first provide a brief overview of the basic structure,operating mechanism,and evaluation parameters of FGFETs,and delve into their material selection and patterning *** ability of FGFETs to sense strains and biomolecular charges opens up diverse application *** specifically analyze the latest strategies for integrating FGFETs into wearable and implantable flexible biomedical sensors,focusing on the key aspects of constructing high-quality flexible biomedical ***,we discuss the current challenges and prospects of FGFETs and their applications in biomedical *** review will provide valuable insights and inspiration for ongoing research to improve the quality of FGFETs and broaden their application prospects in flexible biomedical sensing.

关键词： Flexible Graphene Field-effect transistor Wearable Implantable Biosensor

ERK1/2通路在低氧上调大鼠PASMCs钙激活性氯离子通道表达的作用

在线全文

学校读者我要写书评

暂无评论

中国应用生理学杂志 2017年第1期33卷 47-50页

作者：赵美平马迎春张聪聪黄林静郑梦晓黎关龙应磊王万铁温州医科大学基础医学院病理生理学教研室兰州军区兰州总医院病理科甘肃兰州7300504 浙江省医学科学院卫生学研究所毒理学研究室杭州310013 温州医科大学缺血-再灌注损伤研究所浙江温州325035

目的:探讨钙激活性氯离子通道(CLCA2)在大鼠低氧性肺动脉平滑肌细胞(PASMCs)中m RNA和蛋白表达的变化及其与ERK1/2信号通路的关系。方法:PASMCs随机分为:常氧组(N组),低氧组(H组),DMSO对照组(D组),U0126干预组(U组),Staurosporine aglyc... 详细信息

目的:探讨钙激活性氯离子通道(CLCA2)在大鼠低氧性肺动脉平滑肌细胞(PASMCs)中m RNA和蛋白表达的变化及其与ERK1/2信号通路的关系。方法:PASMCs随机分为:常氧组(N组),低氧组(H组),DMSO对照组(D组),U0126干预组(U组),Staurosporine aglycone干预组(SA组),采用免疫印迹法检测CLCA2蛋白的表达;选用半定量逆转录-聚合酶链反应(RT-PCR)技术测定CLCA2 m RNA水平的表达。结果:PASMCs中CLCA2m RNA和蛋白的表达量,H组较N组明显上调(P<0.01);U组较D组明显上调(P<0.01);SA组较D组m RNA的表达显著下调(P<0.01),蛋白的表达轻微下调。结论:低氧可上调CLCA2中m RNA和蛋白在PASMCs的表达;ERK1/2通路激活剂-Staurosporine aglycone能下调CLCA2在PASMCs中m RNA和蛋白的表达量;ERK1/2通路抑制剂-U0126可上调CLCA2在PASMCs中m RNA和蛋白的表达量。

关键词：钙激活性氯离子通道低氧 PASMCs ERK1/2 大鼠

Low complexity resource allocation and scheduling algorithms for downlink SDMA systems

在线全文

学校读者我要写书评

暂无评论

The Journal of China Universities of Posts and Telecommunications 2009年第5期16卷 33-40页

作者： SUN Kai WANG ying zhang ping College of Electronic Information Engineering Inner Mongolia University Hohhot 010021 China Key Laboratory of Universal Wireless Communications Ministry of Education Beijing University of Posts and Telecommunications Beijing 100876 China

The downlink zero-forcing beamforming strategy in the case of random packet arrivals is investigated. Under this setting, the relevant fairness criterion is the stabilization of all buffer queues which guarantees a bounded average delay for all users. It has been shown that allocating resources to maximize a queue-length-weighted sum of the rates is a stabilizing policy. However, the high complexity of user selection and the feasible rates determination for optimal scheme may prevent the real-time scheduling operation. Two low complexity algorithms are provided taking the channel state, queue state and orthogonality into account. In particular, the authors pick the first user with the largest product between channel gain and queuing length, and select the remaining users to construct candidate user set based on the greedy user selection method or channel orthogonal user selection method. Then, the power and rate allocation for the selected users are implemented based on the modified water-filling method. The complexity of the proposed algorithms is analyzed. The average delay and average throughput are studied in homogeneous scenarios and heterogeneous scenarios, respectively. Simulation results show that the proposed algorithms can take full advantage of the multi-user diversity gain and provide average delay （or throughput） and fairness improvement compared with channel-aware-only schemes.

关键词： space-division multiple access (SDMA) resource allocation scheduling algorithm zero-forcing