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Pancreaticoduodenectomy and pancreaticoduodenectomy combined with superior mesentericportal vein resection for elderly cancer patients

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Hepatobiliary & Pancreatic Diseases International 2014年第4期13卷 428-434页

作者： Jun-Wei Sun ping-ping zhang He Ren Ji-Hui Hao Departments of Pancreatic Cancer Tianjin Medical University Cancer Institute and Hospital Thoracic Oncology Tianjin Medical University Cancer Institute and Hospital

BACKGROUND： There is an increasing frequency of pancreaticoduodenectomy（PD） and PD with superior mesenteric-portal vein（SMPV） resection in elderly cancer patients. The study aimed to investigate the safety and the survival benefits of PD and PD with SMPV resection in patients under or over 70 years of ***： We divided 296 patients who had undergone PD and PD with SMPV resection into two groups according to their ages： under or over 70 years old. The clinical data were compared between the two ***： Preoperative comorbidity rate was higher in elder patients than in younger patients（P=0.001）. The elder patients were more likely to have postoperative complications（P=0.003）.Specifically, complications above grade III were more likely to occur in the elderly patients（P=0.030）. Multivariable analysis showed that age（adjusted OR=2.557, P=0.015） and hypertension（adjusted OR=2.443, P=0.019） were independent predictors of postoperative complications. There was no significant difference in the mortality rates between the two groups（P=0.885）. In the PD with SMPV resection series, elderly patients were more likely to have postoperative complications（P=0.063）, but this difference was not statistically *** was no difference in the survival rate of patients with pancreatic ductal adenocarcinoma between the two *** type（PD vs PD with SMPV resection） did not affect the survival of ***： Age affects postoperative complication in patients undergoing either PD or PD with SMPV ***, extensive experience and advanced perioperative management lower the complication rate to an acceptablelimit. Hence it is safe and worthwhile to perform PD for elderly patients. Because of low numbers in the SMPV subset, we could not conclude whether PD with SMPV resection is feasible in elderly patients.

关键词： pancreaticoduodenectomy elderly cancer outcomes

Presbyphagia:Dysphagia in the elderly

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World Journal of Clinical Cases 2023年第11期11卷 2363-2373页

作者： Hai-Yang Feng ping-ping zhang Xiao-Wen Wang School of Rehabilitation Medicine Weifang Medical UniversityWeifang 261021Shandong ProvinceChina

Dysphagia has been classified as a“geriatric syndrome”and can lead to serious complications that result in a tremendous burden on population health and healthcare resources worldwide.A characteristic age-related change in swa-llowing is defined as“presbyphagia.”Medical imaging has shown some changes that seriously affect the safety and efficacy of ***,there is a general lack of awareness of the effects of aging on swallowing function and a belief that these changes are part of normal *** review provides an overview of presbyphagia,which has been a neglected health problem for a long *** and awareness of dysphagia in the elderly population should be strengthened,and targeted intervention measures should be actively imple-mented.

关键词： Aging Dysphagia Presbyphagia Geriatric syndromes Swallowing

Long-term follow-up of endoscopic papillectomy and the value of preventive pancreatic stent placement(with videos)

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Gastroenterology Report 2023年第1期11卷 486-491页

作者： Yuling Wang Xiaoqing zhang Zhenhua Yang Teng Wang Dongqing Zhu Jie Gao ping-ping zhang Peiqin Wang Xingang Shi Department of Gastroenterology Changhai HospitalNaval Military Medical UniversityShanghaiP.R.China Department of Emergency Changhai HospitalNaval Military Medical UniversityShanghaiP.R.China Department of Nephrology Gongli HospitalPudong New AreaShanghaiP.R.China Department of Radiology Changzheng HospitalNaval Military Medical UniversityShanghaiP.R.China Department of Gastroenterology Changzheng HospitalNaval Military Medical UniversityShanghaiP.R.China

Background:Early-stage ampullary adenomas have only been reported in a small case series on endoscopic ***,this study aimed to evaluate the long-term outcomes of early ampullary adenoma with endoscopic management and identify the risk factors for acute pancreatitis after endoscopic papillectomy(EP).Methods:In this study,115 patients who underwent EP at Changhai Hospital(Shanghai,China)between January 2012 and December 2018 were retrospectively *** was performed at 1,3,6,and 12months after *** were statistically analysed using the t-test or the Mann–Whitney U ***:A total of 107 patients were included in this study and the follow-up period was 75643 *** average age of the 107 patients was 54.6 years and the average tumor size was *** average age of the patients(53.7610.7 years vs 55.2610.5 years,P=0.482),minimum tumor size(13 vs 19mm,P=0.063),and complete resection rate(84.78%vs 85.25%,P=0.947)did not differ significantly between the stent placement and non-stent placement ***-EP acute pancreatitis rates in the non-stent placement and stent placement groups were 11.48%and 4.35%,*** risk of post-EP acute pancreatitis was significantly associated with the preoperative carcinoembryonic antigen level in univariate analysis,but not in multivariate *** risk of post-EP acute pancreatitis was not significantly associated with the placement of the pancreatic stent in either univariate or multivariate ***,delayed proximal pancreatic duct stenosis was not noted in either group during long-term ***:EP is a satisfactory option for treating adenomas of the ampulla of the duodenum.

关键词： endoscopic resection pancreatic duct stent pancreatitis adenoma duodenal papilla

Topological and superconducting properties of monolayered CoN and CoP:A first-principles comparative study

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Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 98-108页

作者： Jiaqing Gao Zhenyu zhang ping Cui International Center for Quantum Design of Functional Materials(ICQD) Hefei National Research Center for Physical Sciences at Microscale(HFNL)University of Science and Technology of ChinaHefei 230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China

Two-dimensional systems that simultaneously harbor superconductivity and nontrivial band topology may serve as appealing platforms for realizing topological superconductivity with promising applications in fault-tolerant quantum ***,based on first-principles calculations,we show that monolayered Co N and Co P with the isovalent Fe Se-like structure are stable in freestanding form,even though their known bulk phases have no resemblance to *** two systems are further revealed to display intrinsic band inversions due to crystal field splitting,and such orderings are preserved with the inclusion of spin-orbit coupling(SOC),which otherwise is able to open a curved band gap,yielding a non-zero Z2 topological invariant in each *** a mechanism of topologicalization is distinctly contrasted with that identified recently for the closely related monolayers of CoX(X=As,Sb,Bi),where the SOC plays an indispensable role in causing a nontrivial band ***,we demonstrate that,by applying equi-biaxial tensile strain,the electron-phonon coupling strength in monolayered CoN can be significantly enhanced,yielding a superconducting transition temperature(Tc)up to 7-12 K for the Coulomb pseudopotential ofμ*=0.2-0.1,while the CoP monolayer shows very low Tc even under pronounced *** different superconducting behaviors can be attributed to different variations in lattice softening and electronic density of states around the Fermi level upon *** central findings enrich the understanding of different mechanisms of band inversions and topologicalization and offer platforms for achieving the coexistence of superconductivity and nontrivial band topology based on two-dimensional systems.

关键词： topological yielding otherwise

Direct capture and separation of CO_(2) from air

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Green Energy & Environment 2024年第3期9卷 413-416页

作者： Siew ping Teong Yugen zhang Institute of Sustainability for Chemicals Energy and Environment(ISCE2)Agency for ScienceTechnology and Research(A*STAR)1 Pesek Road Jurong Island627833SingaporeRepublic of Singapore

Direct air capture(DAC)has attracted increasing interest and investment over the past few *** are a fast-growing number of companies that entered the field and demonstrated DAC carbon removal setups and ***,current DAC methods are still based on solid absorbents or alkali solutions approaches which have low capture efficiency and low energy *** highlight proposed a promising CO_(2) capture technology,an electric energy driven closed-loop system for the direct removal of CO_(2) from ambient air which are based on two individual technologies:Polyam-N-Cu hybrid system promoted CO_(2) capture with ocean as anthropogenic CO_(2) sink and a chloride-mediated electrochemical pH swing system to remove CO_(2) from oceanwater.

关键词： system separation companies

A Fuzzy Trust Management Mechanism with Dynamic Behavior Monitoring for Wireless Sensor Networks

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China Communications 2024年第5期21卷 177-189页

作者： Fu Shiming zhang ping Shi Xuehong School of Artificial Intelligence Chongqing University of EducationChongqing 400065China School of Communications and Information Engineering Chongqing University of Posts and TelecommunicationsChongqing 400065China

Traditional wireless sensor networks(WSNs)are typically deployed in remote and hostile environments for information *** wireless communication methods adopted by sensor nodes may make the network highly vulnerable to various *** encryption and authentication mechanisms cannot prevent attacks launched by internal malicious *** trust-based security mechanism is usually adopted to solve this problem in ***,the behavioral evidence used for trust estimation presents some uncertainties due to the open wireless medium and the inexpensive sensor ***,how to efficiently collect behavioral evidences are rarely *** address these issues,in this paper,we present a trust management mechanism based on fuzzy logic and a cloud ***,a type-II fuzzy logic system is used to preprocess the behavioral evidences and alleviate ***,the cloud model is introduced to estimate the trust values for sensor ***,a dynamic behavior monitoring protocol is proposed to provide a balance between energy conservation and safety *** results demonstrate that our trust management mechanism can effectively protect the network from internal malicious attacks while enhancing the energy efficiency of behavior monitoring.

关键词： behavior monitoring cloud fuzzy trust wireless sensor networks

Heat transfer enhanced inorganic phase change material compositing carbon nanotubes for battery thermal management and thermal runaway propagation mitigation

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Journal of Energy Chemistry 2024年第2期89卷 226-238,I0006页

作者： Xinyi Dai ping ping Depeng Kong Xinzeng Gao Yue zhang Gongquan Wang Rongqi Peng Center for Offshore Engineering and Safety Technology China University of Petroleum(East China)Qingdao 266580ShandongChina College of Chemistry and Chemical Engineering China University of Petroleum(East China)Qingdao 266580ShandongChina

Developing technologies that can be applied simultaneously in battery thermal management(BTM)and thermal runaway(TR)mitigation is significant to improving the safety of lithium-ion battery *** phase change material(PCM)with nonflammability has the potential to achieve this dual *** study proposed an encapsulated inorganic phase change material(EPCM)with a heat transfer enhancement for battery systems,where Na_(2)HPO_(4)·12H_(2)O was used as the core PCM encapsulated by silica and the additive of carbon nanotube(CNT)was applied to enhance the thermal *** microstructure and thermal properties of the EPCM/CNT were analyzed by a series of characterization *** different incorporating methods of CNT were compared and the proper CNT adding amount was also *** preparation,the battery thermal management performance and TR propagation mitigation effects of EPCM/CNT were further investigated on the battery *** experimental results of thermal management tests showed that EPCM/CNT not only slowed down the temperature rising of the module but also improved the temperature uniformity during normal *** peak battery temperature decreased from 76℃to 61.2℃at 2 C discharge rate and the temperature difference was controlled below 3℃.Moreover,the results of TR propagation tests demonstrated that nonflammable EPCM/CNT with good heat absorption could work as a TR barrier,which exhibited effective mitigation on TR and TR *** trigger time of three cells was successfully delayed by 129,474 and 551 s,respectively and the propagation intervals were greatly extended as well.

关键词： Inorganic phase change material Carbon nanotube Battery thermal management Thermal runaway propagation Fire resistance Encapsulation

Chronic administration of triclosan leads to liver fibrosis through hepcidin-ferroportin axis-mediated iron overload

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Journal of Environmental Sciences 2024年第3期137卷 144-154页

作者： Jing Liu Lecong zhang Fang Xu ping zhang Yang Song College of Eco-Environmental Engineering Guizhou Minzu UniversityGuiyang 550025China The Institute of Karst Wetland Ecology Guizhou Minzu UniversityGuiyang 550025China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China

Triclosan(TCS)has been manufactured as an antibacterial compound for half a ***,it is widely used in various personal care products;however,its potential adverse effects raise a lot of ***,we create a long-term oral administration mouse model and identify the corresponding hepatotoxicity of *** discover that daily intragastric administration of 10 mg/kg TCS to mice for 12 weeks results in severe hepatic *** study displays that hepatic iron increased 18%,23%and 29%upon oral TCS treatment for4,8 and 12 weeks,*** by hepatic iron variation,splenic and duodenal iron are increased,which indicates systemic iron *** only excessive iron accumulated in the liver,abnormal hepatic malondialdehyde,prostaglandin synthase 2 and glutathione peroxidase 4 are pointed to *** study uncovers that hepcidin expression increases 7%,10%,4%in serum and 2.4-,4.8-,and 2.3-fold on transcriptional levels upon TCS exposure for 4,8 and 12 weeks,*** together,the mice in the TCS-treated group show disordered systemic iron homeostasis via the upregulated hepatic hepcidin-ferroportin ***,both hepatic iron overload(systemic level)and hepatocyte ferroptosis(cellular level)are accused of TCS-induced liver ***■,an iron scavenger,significantly ameliorates TCS-induced liver *** summary,this study confirms the impact of TCS on liver fibrosis;a critical signal pathway is also *** significance of the current study is to prompt us to reevaluate the“pros and cons”of TCS applications.

关键词： Triclosan Iron metabolism Hepcidin Hepatotoxicity Liver fibrosis

Disturbance Observer-Based Predictive Tracking Control of Uncertain HOFA Cyber-Physical Systems

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IEEE/CAA Journal of Automatica Sinica 2024年第7期11卷 1711-1713页

作者： Da-Wei zhang Guo-ping Liu IEEE the Center for Control Theory and Guidance Technology Harbin Institute of TechnologyHarbin 150001China the Center for Control Science and Technology Southern University of Science and TechnologyShenzhen 518055China

Dear Editor,In this letter,an output tracking control problem of uncertain cyber-physical systems(CPSs)is considered in the perspective of high-order fully actuated(HOFA)system theory,where a lumped disturbance is use... 详细信息

关键词： Observer Uncertain letter