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Fluorescence Retention of Organosilane-polymerized Carbon Dots Inverse Opals in CuCl Suspension

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Chinese Journal of Polymer Science 2018年第5期36卷 555-555,556-562页

作者： ping-ping wu Jun-Chao Liu Zheng Xie Jin-Shan Guo Jing-Xia Wang Institute of Polymer Science and Engineering College of Chemistry and Chemical Engineering Lanzhou University Key Laboratory of Bio-inspired Materials and Interface Sciences Technical Institute of Physics and Chemistry Chinese Academy of Sciences Laboratory of Bioinspired materials School of Future Technology University of Chinese Academy of Sciences Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technique Institute of Physics and Chemistry Chinese Academy of Sciences

A novel and fluorescence retention inverse opal has been achieved from organosilane-polymerized carbon dots（SiCDs）, which is prepared via infiltrating SiCD solution into the interstice of photonic crystal（PC） template, low temperature treatment, heating polymerization and removing the colloidal template. The as-prepared SiCD inverse opals demonstrate close-cell structure, which is completely different from conventional open-cell structure. Then the fluorescence signal of as-prepared sample keeps almost unchanged in CuCl suspension while the fluorescence of SiCD solution can be quenched by CuCl suspension through an effective electron transfer process. This phenomenon can be attributed to the combined effect of high hydrostatic pressure in the pore structure, stable crosslinking network and fluorescence enhancement by PC structure. The SiCD inverse opals have advantages of unique close-cell structure, easy preparation and good repeatability that give an important insight into the design and manufacture of novel and advanced optical devices.

关键词： Carbon dots Inverse opals Close-cell structure Fluorescence retention Inorganic salt solution

Entropic destruction of heavy quarkonium in a rotating hot and dense medium from holography

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Chinese Physics C 2022年第11期46卷 100-105页

作者： ping-ping wu Zi-qiang Zhang Xiangrong Zhu School of Physics and Electronic Information Engineering Henan Polytechnic UniversityJiaozuo 454000China School of Mathematics and Physics China University of GeosciencesWuhan 430074China School of Science Huzhou UniversityHuzhou 313000China

Previous studies have indicated that the peak of the quarkonium entropy at the deconfinement transition can be related to the entropic force,which would induce the dissociation of heavy *** this study,we investigated the entropic force in a rotating hot and dense medium using AdS/CFT *** was found that the inclusion of angular velocity increases the entropic force,thus enhancing quarkonium dissociation,while chemical potential has the same *** results imply that the quarkonium dissociates easier in rotating medium compared with the static case.

关键词： AdS/CFT quark-gluon plasma quarkonium dissociation

Detection and Clinical Significance of DLC1 Gene Methylation in Serum DNA from Colorectal Cancer Patients

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Chinese Journal of Cancer Research 2011年第4期23卷 283-287页

作者： ping-ping wu Ji-hong Zou Ri-ning Tang Yao Yao Cheng-zhong You Deportment of Medical Oncology Jiangsu Cancer Hospital Nanjing 210009 China Department of Medicine Affiliated Zhongda Hospital 5outheast University Nanjing 210009 China Department of Genera/Surgery Jiangsu Cancer Hospital Nanjing 210009China Department of Genera/Surgery Affiliated Zhongda Hospital Southeast University Nanjing 210009 China

Objective: Deleted in liver cancer 1 (DLC1) is a new candidate tumor suppressor gene, whose down-regulation or even silence will result from promoter hypermethylation in various human cancers including colorectal cancer (CRC). The aim of this study is to evaluate the diagnostic role of DLC1 gene methylation in the serum DNA from CRC patients. Methods: This study enrolled 85 CRC patients and 45 patients with benign colorectal diseases. Methylation-specific polymerase chain reaction (MSP) was used to determine the promoter methylation status of DLC1 gene in serum DNA. The combination of DLC1 methylation and conventional tumor markers was further analyzed. Results: Hypermethylation of DLC1 was detected in 42.4% (36/85) of CRC serums, while seldom in the benign controls (8.9%, 4/45) (P<0.001). The aberrant DLC1 methylation in serum DNA was not associated with patients’ clinicopathological features and elevated CEA/CA19-9 levels. Furthermore, the combinational analysis of CEA, CA19-9 and DLC1 methylation showed a higher sensitivity and no reduced diagnostic specificity than CEA and CA19-9 combination for CRC diagnosis. Conclusion: The serum DLC1 methylation may be a promising biomarker for the early detection of CRC, which will further increase the diagnostic efficiency in combination with CEA and CA19-9.

关键词： DLC1 Colorectal cancer Methylation Biomarker

Disordered beta-catenin expression and E-cadherin/CDH1 promoter methyiation in gastric carcinoma

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World Journal of Gastroenterology 2006年第26期12卷 4228-4231页

作者： Li Wang Fan Zhang ping-ping wu Xu-Cheng Jiang Lin Zheng Ying-Yan Yu Department of Pathology School of Medicine Shanghai Jiaotong University Shanghai 200025 China

AIM： TO investigate the distribution of beta-catenin in nuclei or membrane/cytoplasm of gastric carcinoma cells, the relationship between E-cadherin gene methylation and its expression, and the role of beta-catenin and E-cadherin as potential molecular markers in predicting tumor infiltration. METHODS： Twenty-nine cases of gastric carcinoma, classified as diffuse and intestinal variants, were selected for study. Nuclear and cytoplasmic proteins were purified and beta-catenin content was detected by ELISA. DNA methylation of E-cadherin/CDH1 gene promoter was studied by methylation-specific PCR and compaired with E-cadherin expression detected by immunohistochemistry. RESULTS： In 27 cases of gastric carcinoma, the ratio of beta-catenin content between nuclei and membrane/ cytoplasm was correlated with the T-classification （r = 0.392, P = 0.043）. The significance was present between T2 and T3 groups. No correlation was detected between diffuse and intestinal variants in terms of their betacatenin distribution. In 21 cases of diffuse variants of gastric carcinoma, there was a difference in E-cadherin expression between CDH1 gene-methylated group and non-methylated group （29 % vs 71%, P = 0.027）. No correlation between CDH1 gene methylation and T-classification was found, neither was the significance between E-cadherin expression and tumor infiltration grade. CONCLUSION： Comparative analysis of nuclear and membrane/cytoplasmic beta-catenin can predict local tumor infiltration. E-cadherin/CDH1 gene methylation is an important cause for its gene silence in diffuse variant gastric carcinoma. Methylation of CDH1 gene in the absence of E-cadherin is an early event in gastric carcinogenesis.

关键词： Gastric carcinoma Beta-catenin E-cadherin DNA methylation

Subcutaneous fat thickness and abdominal depth are risk factors for surgical site infection after gastric cancer surgery

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World Journal of Clinical Cases 2023年第33期11卷 8013-8021页

作者： Kuan-Yong Yu Rong-Kang Kuang ping-ping wu Guang-Hui Qiang Department of Gastrointestinal Surgery Nanjing Jiangbei HospitalNanjing 210044Jiangsu ProvinceChina Department of Endocrinology Nanjing Jiangbei HospitalNanjing 210044Jiangsu ProvinceChina

BACKGROUND Surgical site infection(SSI)is one of the most common complications after gastric cancer(GC)*** occurrence of SSI can lead to a prolonged postoperative hospital stay and increased medical expenses,and it can also affect postoperative rehabilitation and the quality of life of *** fat thickness(SFT)and abdominal depth(AD)can be used as predictors of SSI in patients undergoing radical resection of *** To explore the potential relationship between SFT or AD and SSI in patients undergoing elective radical resection of *** Demographic,clinical,and pre-and intraoperative information of 355 patients who had undergone elective radical resection of GC were retrospectively collected from hospital electronic medical *** analysis was performed to screen out the significant parameters,which were subsequently analyzed using binary logistic regression and receiver-operating characteristic curve *** The prevalence of SSI was 11.27%(40/355).Multivariate analyses revealed that SFT[odds ratio(OR)=1.150;95%confidence interval(95%CI):1.090-1.214;P<0.001],AD(OR=1.024;95%CI:1.009-1.040;P=0.002),laparoscopic-assisted surgery(OR=0.286;95%CI:0.030-0.797;P=0.017),and operation time(OR=1.008;95%CI:1.001-1.015;P=0.030)were independently associated with the incidence of SSI after elective radical resection of *** addition,the product of SFT and AD was a better potential predictor of SSI in these patients than either SFT or AD *** SFT and AD are independent risk factors and can be used as predictors of SSI in patients undergoing radical resection of GC.

关键词： Subcutaneous fat thickness Abdomen depth Surgical site infection Gastric cancer Radical resection Risk factors

Spontaneous versus posed smile recognition via region-specific texture descriptor and geometric facial dynamics

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Frontiers of Information Technology & Electronic Engineering 2017年第7期18卷 955-967页

作者： ping-ping wu Hong LIU Xue-wu ZHANG Yuan GAO MOE Key Laboratory of Machine Perception Peking University Beijing 100871 China Engineering Lab on Intelligent Perception for Internet of Things Peking University Shenzhen Graduate School Shenzhen 518055 China Department of Computer Science Christian-Albrechts University Kiel 24118 Germany

As a typical biometric cue with great diversities, smile is a fairly influential signal in social interaction, which reveals the emotional feeling and inner state of a person. Spontaneous and posed smiles initiated by different brain systems have differences in both morphology and dynamics. Distinguishing the two types of smiles remains challenging as discriminative subtle changes need to be captured, which are also uneasily observed by human eyes. Most previous related works about spontaneous versus posed smile recognition concentrate on extracting geometric features while appearance features are not fully used, leading to the loss of texture information. In this paper, we propose a region-specific texture descriptor to represent local pattern changes of different facial regions and compensate for limitations of geometric features. The temporal phase of each facial region is divided by calculating the intensity of the corresponding facial region rather than the intensity of only the mouth region. A mid-level fusion strategy of support vector machine is employed to combine the two feature types. Experimental results show that both our proposed appearance representation and its combination with geometry-based facial dynamics achieve favorable performances on four baseline databases： BBC, SPOS, MMI, and UvA-NEMO.

关键词： Facial landmark localization Geometric feature Appearance feature Smile recognition

Practice and reflection on the teaching of the reproductive system

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Medical Bulletin of Shanghai Jiaotong University 2015年第2期27卷 143-148页

作者： Zhi-de DING ping-ping wu Ting-ting wu Yong FAN Ya-li XU Department of Anatomy Histology and EmbryologyShanghai Jiao Tong University School of Medicine Department of Pathology Shanghai Jiao Tong University School of Medicine

Objective To review and explore the advantages and disadvantages of the teaching of the reproductive system in Shanghai Jiao Tong University School of Medicine,in order to provide a feasible scheme for the subsequent reform of the teaching system,including the syllabus design and the optimization of the teaching method,*** With the one-year practice in the teaching of the reproductive system,this paper has explored the achievements in the implementation of this teaching system from three aspects,including the teaching experience and feelings of teachers,student questionnaires and test ***,this paper has also deeply analyzed some problems that may exist or be derived from the teaching practice in that teaching *** The new teaching method has huge differences from the traditional"discipline-oriented"teaching method in the curricular design,teachers’lecture form,students’learning skills and examination types,*** is more important,the new teaching method will significantly renew the concepts of both teaching and *** The method of the systemic teaching is one of the critical ways to realize the reform of the medical education,and can also provide the necessary basis for the cultivation of professional high-quality teachers required in the medical education.

关键词： Systemic teaching reproductive system teaching method medical education

“One stone, two birds”: Salt template enabling porosity engineering and single metal atom coordinating toward high-performance zinc-ion capacitors

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Journal of Energy Chemistry 2025年第1期100卷 637-645页

作者： Chunliu Zhu Huanyu Liang ping Li Chenglong Qiu Jingyi wu Jingwei Chen Weiqian Tian Yue Zhu Zhi Li Huanlei Wang School of Materials Science and Engineering Ocean University of China Department of Chemical and Materials Engineering University of Alberta

Zinc-ion hybrid capacitors （ZIHCs） have received increasing attention as energy storage devices owing to their low cost,high safety,and environmental ***,their progress has been hampered by low energy and power density,as well as unsatisfactory long-cycle stability,mainly due to the lack of suitable electrode *** this context,we have developed manganese single atoms implanted in nitrogen-doped porous carbon nanosheets （MnSAs/NCNs） using a metal salt template method as cathodes for *** metal salt serves a dual purpose in the synthesis process:It facilitates the uniform dispersion of Mn atoms within the carbon matrix and acts as an activating agent to create the porous *** applied in ZIHCs,the MnSAs/NCNs electrode demonstrates exceptional performance,including a high capacity of 203 m Ah g-1,an energy density of 138 Wh kg-1at 68 W kg-1,and excellent cycle stability with 91%retention over 10,000 *** calculations indicate that the introduced Mn atoms modulate the local charge distribution of carbon materials,thereby improving the electrochemical *** work demonstrates the significant potential of carbon materials with metal atoms in zinc-ion hybrid capacitors,not only in enhancing electrochemical performance but also in providing new insights and methods for developing high-performance energy storage devices.

关键词： Zinc ion hybrid capacitors Cathodes Carbon materials Heteroatoms Single atoms

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脑血管病临床研究进展

中国现代神经疾病杂志 2018年第2期18卷 89-94页

作者：蒋燕萍曾玉萍吴波四川大学华西医院神经内科成都610041

我国国民经济和社会发展第十二个五年规划(简称"十二五")时期,脑血管病临床研究取得重大进展,高危非致残性脑血管事件的抗血小板治疗、规范化缺血性卒中二级预防、社区无症状性缺血性卒中流行病学调查、中药治疗缺血性卒中横断面研究、... 详细信息

我国国民经济和社会发展第十二个五年规划(简称"十二五")时期,脑血管病临床研究取得重大进展,高危非致残性脑血管事件的抗血小板治疗、规范化缺血性卒中二级预防、社区无症状性缺血性卒中流行病学调查、中药治疗缺血性卒中横断面研究、血糖对急性缺血性卒中预后的影响、缺血性卒中合并慢性肾脏病和脑微出血、缺血性脑血管病生物学标志物、线粒体脑肌病伴高乳酸血症和卒中样发作与脑萎缩、脑出血围术期血压管理、预测血管结构异常性脑出血预后量表、脑血管病流行病学调查等项研究成果分别发表于国内外重要期刊,本文拟对上述研究进展进行简要综述。

关键词：脑血管障碍中国综述