检索结果-南通市图书馆

Esophageal myoepithelial carcinoma:Four case reports

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第9期10卷 2938-2947页

作者： Hao Lu hui-ping zhao Yi-Yang Liu Juan Yu Rui Wang Jian-Bo Gao Department of Radiology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina

BACKGROUND Myoepithelial carcinoma(MC)is a rare malignant neoplasm that mainly occurs in the salivary *** can be confused with many other tumors when arising outside the salivary glands because it presents with a wide spectrum of cytomorphological and immunohistochemical *** the best of our knowledge,esophageal MC has not been previously *** purpose of this study was to describe the imaging and clinicopathological features of esophageal MC to improve the understanding of the *** SUMMARY Three men and one woman diagnosed with esophageal MC were enrolled in this *** primary clinical symptom was *** mass was mainly located in the middle *** tests revealed that two patients who underwent tumor abnormal protein were *** resection was performed for all patients with no adjuvant ***-eosin staining showed infiltrative growth of epithelial cells with hyperchromatic and pleomorphic nuclei toward the *** showed that all patients were positive for P63,and most patients were positive for SOX-10,AE1/AE3,P40,and *** Ki-67 values were all higher than 60%.Patient one died one month after discharge from an unknown *** two lost to *** patient three’s four-month review,enhanced computed tomography(CT)showed anastomosis recurrence and bilateral lung *** abandoned treatment and lost to *** four attended review appointments regularly and remained in a good general *** Here,we present the first report of esophageal MC and review the relevant *** MC is more likely to occur in the middle esophagus in older patients with male dominance.A fungating type observed on CT scanning may help narrow down the differential *** change or necrosis may occur in larger *** final diagnosis should be made according to the pathological *** treatment for MC is surgical resec

关键词： Myoepithelial carcinoma Esophagus Computed tomography Diagnosis Immunohistochemistry Prognostic Case report

Global variance reduction method for global Monte Carlo particle transport simulations of CFETR

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2017年第8期28卷 126-132页

作者： Xing-Chen Nie Jia Li Song-Lin Liu Xiao-Kang Zhang ping-hui zhao Min-You Ye German Vogel Xiao Yang Qing-Jun Zhu School of Nuclear Science and Technology University of Science and Technology of China Institute of Plasma Physics Chinese Academy of Sciences

It can be difficult to calculate some under-sampled regions in global Monte Carlo radiation transport calculations. The global variance reduction(GVR) method is a useful solution to the problem of variance reduction everywhere in a phase space. In this research, a GVR procedure was developed and applied to the Chinese Fusion Engineering Testing Reactor(CFETR). A cylindrical CFETR model was utilized for comparing various implementations of the GVR method to find the *** was found that the flux-based GVR method could ensure more reliable statistical results, achieving an efficiency being 7.43 times that of the analog case. A mesh tally of the scalar neutron flux was chosen for the GVR method to simulate global neutron transport in the CFETR *** distributed uniformly in the system were sampled adequately through ten iterations of GVR weight *** voxels were scored, and the average relative error was 2.4% in the ultimate step of the GVR iteration.

关键词：方差模拟粒子输运 GCR 辐射输运蒙特卡洛空间问题聚变工程

在线全文

学校读者我要写书评

暂无评论

铁路局安全问题分层管理系统

铁道运营技术 2007年第2期13卷 18-20页

作者：平朝辉柳州铁路局科研所工程师广西柳州545007

针对铁路安全问题管理的难度大、效率低的情况,采用自上而下的软件系统设计方法,开发了铁路局安全问题分层管理系统,实现了安全问题的统计、查询和分析,还具有字典维护、安全问题信息传递,规范报表表格打印、数据备份、日志管理等功能。

关键词：铁路局安全问题管理系统分类查询统计分析

Unraveling the significance of cobalt on transformation kinetics,crystallography and impact toughness in high-strength steels

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 380-390页

作者： Yishuang Yu Jingxiao zhao Xuelin Wang hui Guo Zhenjia Xie Chengjia Shang Collaborative Innovation Center of Steel Technology University of Science and Technology BeijingBeijing 100083China School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China

This work reveals the significant effects of cobalt(Co)on the microstructure and impact toughness of as-quenched highstrength steels by experimental characterizations and thermo-kinetic *** results show that the Co-bearing steel exhibits finer blocks and a lower ductile-brittle transition temperature than the steel without ***,the Co-bearing steel reveals higher transformation rates at the intermediate stage with bainite volume fraction ranging from around 0.1 to *** improved impact toughness of the Co-bearing steel results from the higher dense block boundaries dominated by the V1/V2 variant ***,the addition of Co induces a larger transformation driving force and a lower bainite start temperature(BS),thereby contributing to the refinement of blocks and the increase of the V1/V2 variant *** findings would be instructive for the composition,microstructure design,and property optimization of high-strength steels.

关键词： high-strength steel cobalt transformation kinetics crystallography impact toughness

Multivariable Process Control Using Analytical Decoupling and Disturbance Observer

在线全文

学校读者我要写书评

暂无评论

Multivariable Process Control Using Analytical Decoupling an...

A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

第24届中国控制与决策会议

作者： Guo-Zhong Li, Bo Xiang, ping Zhou, Jin-hui zhao Electrical Department of Tangshan College, Tanshan, Heibei 063020, China Northeastern University, Shenyang 110819, China,

Control a closed-circuit grinding process is a challenging problem due to its complex dynamic characteristics and heavy interactions among the control loops. Especially the various process disturbances and uncertain dynamics have a great influence on the control performances of the closed-loop system. In this paper, a compound control strategy by combining the analytical decoupling control and disturbance observer （DOB） technique is proposed to handle such an intricate multivariable process. The decoupling controller acts as prefiter and is used to generate appropriate control actions such that a desired setpoint tracking response is achieved. The DOB is employed to estimate the various disturbances and suppress them by feedforward compensation design. Control studies have been performed by simulation tests for setpoint tracking and disturbance rejection problems.

关键词： Grinding process analytical decoupling disturbance observer multivariable control

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： Xiao Liang Xingping Quan Xiaorui Geng Yujing Huang Yonghua zhao Lei Xi Zhen Yuan ping Wang Bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

2017年8月8日九寨沟M7.0地震及余震震源机制解与发震构造分析

在线全文

学校读者我要写书评

暂无评论

地球物理学报 2017年第10期60卷 4083-4097页

作者：易桂喜龙锋梁明剑张会平赵敏叶有清张致伟祁玉萍王思维宫悦乔惠珍汪智邱桂兰苏金蓉四川省地震局成都610041 四川赛思特科技有限责任公司成都610041 中国地震局地质研究所地震动力学国家重点实验室北京100029

2017年8月8日在青藏高原东缘四川省九寨沟县发生M7.0级强烈地震,极震区烈度达Ⅸ度,但无明显地表破裂,一定程度上限制了发震构造的确定和后续地震危险性判定.本文基于截止至2017年8月14日的地震资料,采用多阶段定位方法,对主震及余震进... 详细信息

2017年8月8日在青藏高原东缘四川省九寨沟县发生M7.0级强烈地震,极震区烈度达Ⅸ度,但无明显地表破裂,一定程度上限制了发震构造的确定和后续地震危险性判定.本文基于截止至2017年8月14日的地震资料,采用多阶段定位方法,对主震及余震进行了重新定位,同时,利用CAP波形反演方法,获得了M7.0主震与13次M_L≥4.0级余震的震源机制解和震源矩心深度,进而初步分析了本次地震的发震构造.结果显示,九寨沟M7.0地震的矩震级M_w6.4,震源矩心深度5 km,表明主震发生在上地壳浅部,与2003年伊朗巴姆(Bam)M_w6.5地震特征极为相似;12次M_L≥4.0级余震的震源矩心深度6~12 km,显示这些余震发生在主震下部,仅1次例外.重新定位后的余震震中呈NW-SE向窄带展布,位于近NS向的岷江断裂与近EW向的东昆仑断裂带东端分支塔藏断裂所夹持的区域,余震带长轴长约38 km,主震位于余震带中部.根据余震震中分布、主震及余震震源机制解等,推测本次九寨沟M7.0地震及其余震的主发震构造为位于岷江断裂与塔藏断裂之间的树正断裂.震源机制解揭示,树正断裂呈左旋走滑,走向约152°,近SE,倾向SW,倾角约70°,该断裂应属于东昆仑断裂东端的分支断裂之一,或与东南侧的虎牙断裂构成统一断裂系.

关键词：九寨沟M7.0地震重新定位震源机制发震构造树正断裂

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

在线全文

学校读者我要写书评

暂无评论

Science China Life Sciences 2025年第1期 300-302页

作者： Ze-Min Lin Mai Xiang Wen-hui Wei Shu-hui Fan Li Chen Jie Wang Xiao-Qian Yang Chun-Hao Yang Shi-Jun He Jian-ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

关键词：

同方期刊数据库

在线全文

学校读者我要写书评

暂无评论

肾移植后移植物抗宿主病一例的诊治

中华器官移植杂志 2018年第4期39卷 203-208页

作者：杜敦峰周平郭晖赵圆圆陈知水蒋继贫华中科技大学同济医学院附属同济医院器官移植研究所器官移植教育部重点实验室卫生部器官移植重点实验室武汉430030

目的探讨实体器官移植后发生移植物抗宿主病（GVHD）的诊治方法和可能的发病机制.方法回顾性分析1例罕见肾移植术后GVHD受者的诊治经过并复习相关文献.受者肾移植术后50d因皮肤散发皮损再次入院,皮肤活体组织检查病理提示为GVHD.为明... 详细信息

目的探讨实体器官移植后发生移植物抗宿主病（GVHD）的诊治方法和可能的发病机制.方法回顾性分析1例罕见肾移植术后GVHD受者的诊治经过并复习相关文献.受者肾移植术后50d因皮肤散发皮损再次入院,皮肤活体组织检查病理提示为GVHD.为明确诊断,进一步对患者进行了外周血CD3＋淋巴细胞富集后的短串联重复序列（short tandem repeats,STR）嵌合分析和皮肤组织供者特异性人类白细胞抗原（HLA）抗体免疫荧光实验,同时进行降低免疫抑制为主导的治疗.结果 STR分析结果显示,患者外周血淋巴细胞嵌合率为0,但皮肤组织供者特异性HLA抗体免疫荧光结果证实,皮肤组织大量浸润淋巴细胞为供者来源,从而确诊为肾移植术后GVHD.经过降低免疫抑制治疗,小剂量甲泼尼龙冲击治疗后,该患者迅速好转出院,目前肾功能正常.结论结合文献复习,外周血STR嵌合分析和供者特异性HLA染色是确诊实体器官移植后的GVHD有力手段;肾移植术后的GVHD预后较好;推测实体器官移植后GVHD可能是免疫抑制的结果.

关键词：肾移植移植物抗宿主病短串联重复序列免疫荧光