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Endoscopic features and treatments of gastric cystica profunda

World Journal of Gastroenterology 2024年第7期30卷 673-684页

作者： Zi-Han Geng Yan Zhu Pei-Yao Fu Yi-Fan Qu Wei-Feng Chen Xia Yang ping-hong zhou Quan-Lin Li Endoscopy Center and Endoscopy Research Institute Zhongshan HospitalFudan UniversityShanghai 200032China

BACKGROUND Gastric cystica profunda(GCP)represents a rare condition characterized by cystic dilation of gastric glands within the mucosal and/or submucosal *** is often linked to,or may progress into,early gastric cancer(EGC).AIM To provide a comprehensive evaluation of the endoscopic features of GCP while assessing the efficacy of endoscopic treatment,thereby offering guidance for diagnosis and *** This retrospective study involved 104 patients with GCP who underwent endoscopic *** demographic and clinical data,regular patient followups were conducted to assess local *** Among the 104 patients diagnosed with GCP who underwent endoscopic resection,12.5%had a history of previous gastric *** primary site predominantly affected was the cardia(38.5%,n=40).GCP commonly exhibited intraluminal growth(99%),regular presentation(74.0%),and ulcerative mucosa(61.5%).The leading endoscopic feature was the mucosal lesion type(59.6%,n=62).The average maximum diameter was 20.9±15.3 mm,with mucosal involvement in 60.6%(n=63).Procedures lasted 73.9±57.5 min,achieving complete resection in 91.3%(n=95).Recurrence(4.8%)was managed via either surgical intervention(n=1)or through endoscopic resection(n=4).Final pathology confirmed that 59.6%of GCP cases were associated with *** analysis indicated that elderly males were more susceptible to GCP associated with ***,multivariate analysis identified lesion morphology and endoscopic features as significant risk *** analysis demonstrated no statistically significant difference in recurrence between GCP with and without EGC(P=0.72).CONCLUSION The findings suggested that endoscopic resection might serve as an effective and minimally invasive treatment for GCP with or without EGC.

关键词： Gastric cystica profunda Early gastric cancer Endoscopic features Endoscopic resection Endoscopy

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Detection accuracy of target accelerations based on vortex electromagnetic wave in keyhole space

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Chinese Physics B 2024年第2期33卷 283-290页

作者：郭凯雷爽雷艺周红平郭忠义 School of Computer and Information Hefei University of TechnologyHefei 230009China

The influence of the longitudinal acceleration and the angular acceleration of detecting target based on vortex electromagnetic waves in keyhole space are *** spectrum spreads of different orbital angular momentum(OAM)modes in different non-line-of-sight situations are *** errors of target accelerations in detection are calculated and compared based on the OAM spectra spreading by using two combinations of composite OAM modes in the keyhole *** to the research,the effects about spectrum spreads of higher OAM modes are more *** error in detection is mainly affected by OAM spectrum spreading,which can be reduced by reasonably using different combinations of OAM modes in different practical *** above results provide a reference idea for investigating keyhole effect when vortex electromagnetic wave is used to detect accelerations.

关键词： vortex electromagnetic waves detect accelerations keyhole space spectrum spread

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Hybrid argon plasma coagulation for the treatment of Barrett’s esophagus:A prospective,multicenter study

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World Journal of Clinical Cases 2024年第19期12卷 3866-3872页

作者： Dong Wang Yan Chen Feng Ji Jian-Wei Hu ping-hong zhou Shu-Chang Xu Ying Chen Li-ping Ye Guo-Liang Ye Rui Li Zhao-Shen Li Department of Gastroenterology Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai 200011China Department of Gastroenterology Changhai HospitalShanghai 200438China Department of Gastroenterology The First Affiliated Hospital Zhejiang University School of MedicineHangzhou 311399Zhejiang ProvinceChina Endoscopy Center Zhongshan HospitalFudan UniversityShanghai 200032China Endoscopy Center Tongji Hospital of Tongji UniversityShanghai 200092China Department of Gastroenterology Taizhou Hospital of Zhejiang ProvinceTaizhou 318001Zhejiang ProvinceChina Department of Gastroenterology The Affiliated Hospital of Medicine SchoolNingbo UniversityNingbo 315021Zhejiang ProvinceChina Department of Gastroenterology The First Affiliated Hospital of Soochow UniversitySuzhou 215006Jiangsu ProvinceChina

BACKGROUND The incidence of Barrett’s esophagus(BE)in China is lower compared to the Western ***,studies conducted in the Chinese population has been *** current treatment options available for BE treatment includes argon plasma coagulation(APC),radiofrequency ablation and cryoablation,all with varying degrees of *** To determine the efficacy and safety of HybridAPC in the treatment of *** The study cohort consisted of patients with BE who underwent HybridAPC ablation *** procedures were performed by seven endoscopists from different tertiary *** duration of the procedure,curative rate,complications and recurrent rate by 1-year follow-up were *** Eighty individuals were enrolled for treatment from July 2017 to June 2020,comprising of 39 males and 41 females with a median age of 54 years(range,30 to 83 years).The technical success rate of HybridAPC was 100%and the overall curative rate was 98.15%.No severe complications occurred during the *** cases were classified as short-segment BE and long-segment *** with short-segment BE were all considered cured without ***-six patients completed the one-year follow-up without ***-four percent had mild dysplasia which were all resolved with one post-procedural *** mean duration of the procedure was 10.94±6.52 *** Treatment of BE with HybridAPC was found to be a simple and quick procedure that is safe and effective during the short-term follow-up,especially in cases of short-segment *** technique could be considered as a feasible alternative ablation therapy for BE.

关键词： Barrett’s esophagus Hybrid argon plasma coagulation Ablation treatment Prospective study Multicenter study

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Endoscopic resection for calcifying fibrous tumors of the gastrointestinal tract

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World Journal of Clinical Oncology 2024年第2期15卷 282-289页

作者： Zi-Han Geng Yan Zhu Pei-Yao Fu Yi-Fan Qu Shi-Yao Chen Yun-Shi Zhong Yi-Qun Zhang Wei-Feng Chen Wen-Zheng Qin Jian-Wei Hu Ming-Yan Cai Li-Qing Yao Quan-Lin Li ping-hong zhou Endoscopy Center and Endoscopy Research Institute Zhongshan HospitalFudan UniversityShanghai 200032China Shanghai Collaborative Innovation Center of Endoscopy Shanghai 200032China

BACKGROUND Calcifying fibrous tumors(CFTs)are rare mesenchymal lesions that can occur in various sites throughout the body,including the tubular gastrointestinal(GI)*** To analyze the clinical findings of 36 patients with GI tract CFTs to provide guidance for diagnosis and *** This retrospective study included 36 patients diagnosed with CFTs of the GI *** collected demographic and clinical information and conducted regular follow-ups to assess for local *** The stomach was the most commonly involved site,accounting for 72.2%of the 36 *** mucosal resection(n=1,2.8%),endoscopic submucosal dissection(n=14,38.9%),endoscopic full-thickness resection(n=16,44.4%),and submucosal tunneling endoscopic resection(n=5,13.9%)were used to resect calcifying fibrous ***,34(94.4%)CFTs underwent complete endoscopic resections with a mean procedure time of 39.8±29.8 *** average maximum diameter of the tumors was 10.6±4.3 *** complications,such as bleeding or perforation,occurred during an average hospital stay of 2.9±1.2 *** addition,two patients developed new growth of CFTs near the primary tumor sites,and none of the patients developed distant metastases during the follow-up *** GI tract CFTs are rare and typically benign tumors that can be effectively managed with endoscopic procedures.

关键词： Endoscopic resection Calcifying fibrous tumor Gastrointestinal tract

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Beamline design for multipurpose muon beams at CSNS EMuS

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Nuclear Science and Techniques 2024年第5期35卷 1-12页

作者： Yang hong Ying-Peng Song Lu-ping zhou Jing-Yu Tang Zhi-Hao zhou Nikolaos Vassilopoulos Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China University of Chinese Academy of Sciences Beijing 100049China Radiotherapy Physics and Technology Center Cancer CenterWest China HospitalSichuan UniversityChengdu 610041China Xi’an Jiaotong University Health Science Center Xi’an 710049China Department of Radiation Oncology First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710049China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China

A new muon beam facility,called the Experimental Muon Source(EMuS),was proposed for construction at the China Spallation Neutron Source(CSNS).The design of the complex muon beamlines for the EMuS baseline scheme,which is based on superconducting solenoids,superferric dipoles and room-temperature magnets,is presented *** muon beams,including surface muons,decay muons and low energy muons,have been developed for multipurpose *** optics design and simulation results of the trunk beamline and branch beamlines are *** a proton beam power of 25 kW at a standalone target station that consists of a conical graphite target and high-field superconducting solenoids,the muon beam intensity in the trunk beamline varies from 10^(7)/s for surface muons to 10^(10)/s for high-momentum decay *** at the endstations,these values vary from 10^(5)/s for surface muons to 10^(8)/s for decay muons.

关键词： Surface muons Decay muons Muon beamline Superconducting solenoids Multi-channel electrostatic separator

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Study of the reaction mechanism for preparing powdered activated coke with SO_(2)adsorption capability via one-step rapid activation method under flue gas atmosphere

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Chinese Journal of Chemical Engineering 2024年第1期65卷 158-168页

作者： Binxuan zhou Jingcai Chang Jun Li Jinglan hong Tao Wang Liqiang Zhang ping zhou Chunyuan Ma School of Environmental Science and Engineering Shandong UniversityQingdao 266237China School of Energy and Power Engineering Shandong UniversityJinan 250061China Weihai Research Institute of Industrial Technology of Shandong University Weihai 264209China

In this study,the impact of different reaction times on the preparation of powdered activated carbon(PAC)using a one-step rapid activation method under flue gas atmosphere is investigated,and the underlying reaction mechanism is *** indicate that the reaction process of this method can be divided into three stages:stage I is the rapid release of volatiles and the rapid consumption of O_(2),primarily occurring within a reaction time range of 0-0.5 s;stage II is mainly the continuous release and diffusion of volatiles,which is the carbonization and activation coupling reaction stage,and the carbonization process is the main in this *** stage mainly occurs at the reaction time range of 0.5 -2.0 s when SL-coal is used as material,and that is 0.5-3.0 s when JJ-coal is used as material;stage III is mainly the activation stage,during which activated components diffuse to both the surface and interior of *** stage mainly involves the reaction stage of CO_(2)and H2O(g)activation,and it mainly occurs at the reaction time range of 2.0-4.0 s when SL-coal is used as material,and that is 3.0-4.0 s when JJ-coal is used as ***,the main function of the first two stages is to provide more diffusion channels and contact surfaces/activation sites for the diffusion and activation of the activated components in the third *** the reaction mechanism would serve as a crucial reference and foundation for designing the structure,size of the reactor,and optimal positioning of the activator nozzle in PAC preparation.

关键词： Reaction mechanism Powdered activated coke preparation SO_(2)adsorption One-step rapid activation Flue gas atmosphere

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Manipulating submolecular-scale phototautomerization

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Science China Materials 2024年第6期67卷 2048-2050页

作者： ping zhou hongliang Chen Stoddart Institute of Molecular Science Department of ChemistryZhejiang UniversityHangzhou 310058China Zhejiang-Israel Joint Laboratory of Self-Assembling Functional Materials ZJU-Hangzhou Global Scientific and Technological Innovation CenterZhejiang UniversityHangzhou 311215China

A recent study on the submolecular-scale control of phototautomerization methods and the underlying reaction mechanisms was reported in Nature Nanotechnology by Guillaume and co-workers[1],elucidating how the field confinement effect generated by the scanning tunneling microscope(STM)tip precisely triggers the phototautomerization of a free-base phthalocyanine at the submolecular level and demonstrating that the reaction process can be finely controlled by adjusting either the laser excitation wavelength or the position of the tip.

关键词： tunneling excitation phthalocyanine

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Fracture sealing performance of granular lost circulation materials at elevated temperature:A theoretical and coupled CFD-DEM simulation study

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Petroleum Science 2024年第1期21卷 567-581页

作者： Chong Lin Qi-Cong Xu Lie-Xiang Han Gao Li Hai He hong-Ling zhou Ji-ping She CCDC Drilling&Production Technology Research Institute Guanghan618300SichuanChina State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500SichuanChina College of Materials Science and Engineering Chongqing UniversityChongqing400044China State Key Lab of Oil and Gas Reservoir Geology and Exploitation(Chengdu University of Technology) Chengdu610059SichuanChina College of Energy Chengdu University of TechnologyChengdu610059SichuanChina

Lost circulation is a common downhole problem of drilling in geothermal and high-temperature,high-pressure(HTHP)*** circulation material(LCM)is a regular preventive and remedial measure for lost ***,conventional LCMs seem ineffective in high-temperature *** may be due to the changes in the mechanical properties of LCMs and their sealing performance under high-temperature *** understand how high temperature affects the fracture sealing performance of LCMs,we developed a coupled computational fluid dynamics-discrete element method(CFD-DEM)model to simulate the behavior of granular LCMs in *** summarized the literature on the effects of high temperature on the mechanical properties of LCMs and the rheological properties of drilling *** conducted sensitivity analyses to investigate how changing LCM slurry properties affected the fracture sealing efficiency at increasing *** results show that high temperature reduces the size,strength,and friction coefficient of LCMs as well as the drilling fluid ***,softer,and less frictional LCM particles have lower bridging probability and slower bridging *** particles tend to form dual-particle bridges rather than single-particle *** result in a deeper,tighter,but unstable sealing *** drilling fluid viscosity leads to faster and shallower sealing zones.

关键词： Geothermal well drilling HTHP formationLost circulation material CFD-DEM Fracture sealing

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Emerging molecular classifications and therapeutic implications for gastric cancer

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Chinese Journal of Cancer 2016年第8期35卷 393-402页

作者： Tao Chen Xiao-Yue Xu ping-hong zhou Endoscopy Center Zhongshan Hospital of Fudan University Endoscopy Research Institute Fudan University

Gastric cancer(GC) is a highly aggressive and life-threatening *** with radical surgical removal and front-line chemotherapy,more than half of GCs locally relapse and metastasize at a distant *** dismal outcomes reflect the ineffectiveness of a one-size fits-all approach for a highly heterogeneous disease with diverse etiological causes and complex molecular *** recent comprehensive genomic and molecular profiling has led to our deepened understanding of *** emerging molecular classification schemes based on the genetic,epigenetic,and molecular signatures are providing great promise for the development of more effective therapeutic strategies in a more personalized and precise *** this end,the Cancer Genome Atlas(TCGA) research network conducted a comprehensive molecular evaluation of primary GCs and proposed a new molecular classification dividing GCs into four subtypes:Epstein-Barr virus-associated tumors,microsatellite unstable tumors,genomically stable tumors,and tumors with chromosomal *** review primarily focuses on the TCGA molecular classification of GCs and discusses the implications on novel targeted therapy *** believe that these fundamental findings will support the future application of targeted therapies and will guide our efforts to develop more efficacious drugs to treat human GCs.

关键词： Gastric cancer Molecular classification Personalized therapy The Cancer Genome Atlas research network

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An adaptive energy regulation in a memristive map linearized from a circuit with two memristive channels

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Communications in Theoretical Physics 2024年第3期76卷 42-50页

作者： Feifei Yang ping zhou Jun Ma School of Science Chongqing University of Posts and TelecommunicationsChongqing 430065China College of Electrical and Information Engineering Lanzhou University of TechnologyLanzhou 730050China Department of Physics Lanzhou University of TechnologyLanzhou 730050China

Nonlinear circuits can show multistability when a magnetic flux-dependent memristor(MFDM) or a charge-sensitive memristor(CSM) is incorporated into a one branch circuit,which helps estimate magnetic or electric field *** this paper,two different kinds of memristors are incorporated into two branch circuits composed of a capacitor and a nonlinear resistor,thus a memristive circuit with double memristive channels is *** circuit equations are presented,and the dynamics in this oscillator with two memristive terms are ***,the memristive oscillator is converted into a memristive map by applying linear transformation on the sampled time series for the memristive *** Hamilton energy function for the memristive oscillator is obtained by using the Helmholtz theorem,and it can be mapped from the field energy of the memristive *** energy function for the dual memristive map is suggested by imposing suitable weights on the discrete energy *** dynamical behaviors of the new memristive map are investigated,and an adaptive law is proposed to regulate the firing mode in the memristive *** work will provide a theoretical basis and experimental guidance for oscillator-to-map transformation and discrete map energy calculation.

关键词： Hamilton energy dual memristive map adaptive energy regulation

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