检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

造血干细胞移植在非血液系统疾病中的应用

中华内科杂志 2005年第10期44卷 721-723页

作者：邹萍华中科技大学同济医学院附属协和医院血液科武汉430022

造血干细胞移植（HSCT）治疗血液系统疾病已获得了很好的疗效。近年来，很多实验及临床研究尝试用HSCT治疗自身免疫性疾病（AID）、实体瘤、神经系统疾病和遗传性疾病，并获得成功。

关键词：非血液系统疾病造血干细胞移植自身免疫性疾病神经系统疾病 CT治疗遗传性疾病临床研究实体瘤

Efficacy and Safety of Generic Dasatinib as a Second-line Treatment for Patients with Chronic Myeloid Leukemia:a Multicenter Retrospective Study in Hubei Province,China

在线全文

学校读者我要写书评

暂无评论

Current Medical Science 2018年第6期38卷 1005-1011页

作者： Li-feng CHEN Guo-lin YUAN Zhao-dong ZHONG ping zou Deng-ju LI Yin BAO Hong-bo REN Li MENG Wei-ming LI Department of Hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Hematology Xiangyang Central HospitalXiangyang 441000China Department of Hematology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Hematology Xiangyang No.1 People's HospitalXiangyang 441000China Department of Hematology the First People's Hospital of JingzhouJingzhou 434000China

Dasatinib is a second-generation tyrosine kinase inhibitor (TKI)and it could be used as a second-line treatment for patients with chronic myeloid leukemia (CML).Yinishu,a generic dasatinib made in China,was approved by the China Food and Drug Administration in 2013 and it costs much less than the patented dasatinib *** present study aimed to examine the efficacy and safety of Yinishu as a second-line treatment for CML by comparing the baseline clinical characteristics,rates of adverse events and efficacy between Yinishu and SPRYCEL groups. The results showed that there were no significant differences in the rates of optimal response between Yinishu and SPRYCEL for patients who started second-line treatment because of treatment *** patients who started second-line treatment because of intolerance of first-line treatment, their levels of BCR-ABL1/ABL1 on the international scale (BCR-ABL^IS)was maintained very low throughout the course of Yinishu ***-related adverse events occurred with the same frequency in these two *** was confirmed that Yinishu was effective and safe as a second- line treatment for CML *** may be more suitable for patients who are economically unable to pay for the patented dasatinib SPRYCEL.

关键词： chronic myeloid leukemia generic dasatinib second-line treatment efficacy safety

Functional anatomical hepatectomy guided by indocyanine green fluorescence imaging in patients with localized cholestasis:Report of four cases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2021年第3期13卷 323-329页

作者： Hong-Wei Han Ning Shi Yi-ping zou Yuan-Peng Zhang Ye Lin Zi Yin Zhi-Xiang Jian Hao-Sheng Jin The Second School of Clinical Medicine Southern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of General Surgery Guangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhou 510080Guangdong ProvinceChina

BACKGROUND Liver cancer is a malignant tumor with a high *** present,the most effective treatment is laparoscopic hepatectomy(LH).Indocyanine green fluorescence imaging(ICG-FI)has become an important tool in LH,and the most common fluorescent types of tumors are total fluorescence,partial fluorescence,and rim *** SUMMARY We presented four cases of LH guided by ICG-FI in which we also observed the fourth special fluorescent *** the tumor or intrahepatic stone compresses the adjacent bile duct to cause local cholestasis,the liver segment or subsegment with obstructed bile drainage will show strong *** removal of the lesion together with the fluorescent liver parenchyma may help reduce the risk of tumor or stone *** This type of partial fluorescence can indicate local biliary compression,and the resection method is related to bile drainage,which may be called functional anatomical hepatectomy and ensures radical resection of the lesion.

关键词： Indocyanine green Localized cholestasis Laparoscopic hepatectomy Unique fluorescent phenomenon Functional anatomical hepatectomy Case report

Enhanced expression of epidermal growth factor receptor gene in gastric mucosal cells by the serum derived from rats treated with electroacupuncture at stomach meridian acupoints

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第34期12卷 5557-5561页

作者： Zong-Bao Yang Jie Yan Xiao-ping zou Shou-Xiang Yi Xiao-Rong Chang Ya-ping Lin Xi-ping Li College of Acupuncture and Moxibustion Hunan University of Traditional Chinese Medicine Changsha 410007 Hunan Province China

AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS: The stress-induced gastric mucosal injury in rat model was established by water-immersion and restrained stress methods. 52 rats were randomly divided into: normal group (n = 8), model group (n = 8), model serum group (n = 12), stomach serum group (n = 12), and gallbladder serum group (n = 12). The gastric mucosal cells were separated by pronase-EDTA digestion method and incubated with serum. The EGFR gene expression in gastric mucosal cells was detected by reverse transcription-polymerase chain reaction (RT-PCR) method. RESULTS: Compared with normal group (0.6860 ± 0.0594), the serum derived from rats of the stomach group (1.2272 ± 0.0813, P = 0.00 0.05) and in model serum group (0.8516 ± 0.0409) with an extremely obvious difference (P = 0.001 < 0.01). Furthermore, the EGFR gene expression in stomach serum group was significantly higher than that in gallbladder serum group (P = 0.00 < 0.01). CONCLUSION: The present study shows that serumderived from rats treated with electroacupuncture at stomach meridian acupoints can distinctly increase the EGFR gene expression of gastric mucosal cells. Therefore, there is certain meridian specificity in the serum, which could provide a proof for the TCM theory “particular relation between meridian and internal organ”.

关键词： Electroacupuncture Serum Stomach meridian acupoints Gastric mucosal cells Epidermal growth Factor receptor Gene expression

Adrenocorticotropic hormone combined with magnesium sulfate therapy for infantile epileptic spasms syndrome:a real-world study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第8期20卷 834-847页

作者： Wen He Qiu-Hong Wang Jiu-Wei Li Yang-Yang Wang Xiao-Mei Luo Lin Wan Jing Wang Xiu-Yu Shi Wei-Hua Zhang Fang Fang Li-ping zou Senior Department of Pediatrics the Seventh Medical Center of Chinese PLA General HospitalDepartment of Pediatricsthe First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Neurology Beijing Children’s HospitalCapital Medical UniversityBeijingChina Center of Epilepsy Beijing Institute for Brain DisordersBeijing 100069China

Background Infantile epileptic spasms syndrome(IESS)is a serious disease in infants,and it usually evolves to other epilepsy types or syndromes,especially refractory or super-refractory focal *** adrenocorticotropic hormone(ACTH)is one of the first-line and effective treatment plans for IESS,it has serious side effects and is not sufficiently *** A retrospective study of the clinical outcomes of ACTH combined with magnesium sulfate(MgSO_(4))therapy for IESS in two hospital centers was *** major outcome of the single and combined treatment was evaluated by changes in seizure frequency and improvements in hypsarrhythmia electroencephalography(EEG).To reduce the confounding bias between the two groups,we used SPSS for the propensity score matching(PSM)*** We initially recruited 1205 IESS patients from two Chinese hospitals and treated them with ACTH combined with MgSO_(4) and ACTH *** 1005 patients were enrolled in the treatment(ACTH combined with MgSO_(4):744,ACTH:261),and both treatment plans had a more than 55% response ***,compared to patients treated with ACTH alone,those patients treated with ACTH combined with MgSO_(4) had better performance in terms of the seizure frequency and hypsarrhythmia *** PSM,the two groups also showed significant differences in responder rate[70.8%(95% confidence interval,CI)=66.7%–74.8%)vs.53.8%(95%CI=47.4%–60.2%),P3 months(P<0.05).In addition,the overall incidence of adverse reactions in the ACTH combined with MgSO_(4) group was much lower than that in the ACTH group(31.4%vs.63.1%,P<0.001).During th

关键词： Adrenocorticotropic hormone Clinical trial Infantile epileptic spasms syndrome Magnesium sulfate Real-world study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

粉煤灰水热合成法制备4A型分子筛研究进展

矿产综合利用 2020年第3期 33-39页

作者：邹萍神华准能资源综合开发有限公司研发中心内蒙古鄂尔多斯010300

为了将粉煤灰变废为宝,本文综述了近五年来,以粉煤灰为原料,采用普遍的水热合成法,制备4A分子筛的研究现状,分析了现有技术的优缺点,从而引领出低成本、高效率、简单的工艺技术路线。文中以粉煤灰预处理方式的不同进行分类、总结,并对... 详细信息

为了将粉煤灰变废为宝,本文综述了近五年来,以粉煤灰为原料,采用普遍的水热合成法,制备4A分子筛的研究现状,分析了现有技术的优缺点,从而引领出低成本、高效率、简单的工艺技术路线。文中以粉煤灰预处理方式的不同进行分类、总结,并对目前的工艺路线、参数设置、性能优化及应用推广方面做了具体分析。得出主要结论如下:粉煤灰焙烧活化水热合成建议采取"粉煤灰与碳酸钠混合研磨→微波辅助焙烧活化→微波辅助水热合成"工艺路线;粉煤灰直接提取硅铝源水热合成方式,是在粉煤灰提取化工原料过程中获取硅铝源,具有产业化前景;产品性能及应用方面需要全面、系统、深入研究,以期获取经济、社会及环保效益的共赢。

关键词：粉煤灰水热合成 4A分子筛预处理

在线全文

学校读者我要写书评

暂无评论

基于EAHP和GRAP的供应商选择

系统工程理论与实践 2009年第3期29卷 69-75页

作者：邹平袁亦男云南师范大学昆明650092 昆明理工大学管理与经济学院昆明650093

构建了一个以制造商为核心企业的供应商评价指标体系,给出了各个指标的衡量标准.针对供应商选择问题的复杂性,提出了基于EAHP和GRAP相结合的选择决策模型.通过实证研究证明整个评价指标体系及选择模型是可操作、实用和有效的.

关键词：供应商选择指标体系可拓层次分析法灰色关联分析

在线全文

学校读者我要写书评

暂无评论

发展我国现代服务业与利用外资政策研究

国际商务研究 2007年第6期28卷 15-20页

作者：邹平上海对外贸易学院

发展现代服务业和引进外资的关键主要是良好的市场制度环境。引进与利用外资的根本就是要对外商在华投资形成稳定的收益与收益预期。生产成本是分析制造业的基础,交易成本却是分析服务业特别是现代服务业的关键。所以,在新制度经济学基... 详细信息

发展现代服务业和引进外资的关键主要是良好的市场制度环境。引进与利用外资的根本就是要对外商在华投资形成稳定的收益与收益预期。生产成本是分析制造业的基础,交易成本却是分析服务业特别是现代服务业的关键。所以,在新制度经济学基础上的SCP分析范式的创新,就是分析我国如何发展现代服务业和利用外资的理论基础。

关键词：现代服务业 SCP范式交易成本制度环境

在线全文

学校读者我要写书评

暂无评论

合流制溢流污染调蓄池设计容积数值模拟

中国给水排水 2022年第5期38卷 116-121页

作者：邹安平中工武大设计集团有限公司深圳分公司广东深圳518054

按照现有规范计算雨水调蓄池的容积,无法对调蓄后的截污效果进行有效评估。以SWMM为计算工具,通过数值模拟,可以针对具体的流域分析降雨强度、调蓄池容积对污染物的截留效果。以深圳市龙岗区某流域为研究对象,设定不同强度的初期降雨深... 详细信息

按照现有规范计算雨水调蓄池的容积,无法对调蓄后的截污效果进行有效评估。以SWMM为计算工具,通过数值模拟,可以针对具体的流域分析降雨强度、调蓄池容积对污染物的截留效果。以深圳市龙岗区某流域为研究对象,设定不同强度的初期降雨深度,模拟不同初雨径流流量过程和污染物冲刷过程,并对6种污染物(COD、SS、TN、TP、BOD_(5)、NH_(3)-N)累积收集量和调蓄池容积的关系进行数值模拟。结果表明,初雨雨量的差异性对污染物冲刷峰值和总量不具有倍数关系;初期冲刷效应按照递减排序为TN>COD>BOD_(5)>NH_(3)-N>SS,TP没有明显的初期冲刷效应;调蓄容积不低于浓度峰值对应的容积,综合考虑多个污染物的控制效果后可以适当放大;本案例中,调蓄池污染物浓度在峰值之后呈现先快后慢的下降趋势,当调蓄容积不超过10 000 m;时,收集效率仍然较高。调蓄池的主要控制对象和目标值不同时,需要综合考虑后确定调蓄容积。

关键词：合流制溢流初期降雨调蓄池 SWMM