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Gastrointestinal involvement in systemic lupus erythematosus:Insight into pathogenesis, diagnosis and treatment

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World Journal of Gastroenterology 2010年第24期16卷 2971-2977页

作者： Tian, xin-ping Zhang, Xuan Chinese Acad Med Sci Peking Union Med Coll Peking Union Med Coll Hosp Dept Rheumatol Beijing 100730 Peoples R China

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease characterized by the presence of a plethora of autoantibodies and immune complex formation. Virtually every system and organ can be affected by SLE. Gastrointestinal symptoms are com-mon in SLE patients, and more than half of them are caused by adverse reactions to medications and viral or bacterial infections. Though not as common as lu-pus nephritis, SLE-related gastrointestinal involvement is clinically important because most cases can be life-threatening if not treated promptly. Lupus mesenteric vasculitis is the most common cause, followed by pro-tein-losing enteropathy, intestinal pseudo-obstruction, acute pancreatitis and other rare complications such as celiac disease, inflammatory bowel diseases, etc. No specific autoantibody is identified as being associated with SLE-related gastroenteropathy. Imaging studies, particularly abdominal computed tomography scans, are helpful in diagnosing some SLE-related gastroen-teropathies. Most of these complications have good therapeutic responses to corticosteroids and immu-nosuppressive agents. Supportive measures such as bowel rest, nutritional support, antibiotics and proki-netic medications are helpful in facilitating functional recovery and improving the outcome.

关键词： Systemic lupus erythematosus Systemic Vasculitis Gastroenteropathy

New Li-ion Battery Evaluation Research Based on Thermal Property and Heat Generation Behavior of Battery

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Chinese Journal of Chemical Physics 2012年第6期25卷 725-732,I0004页

作者： Zhe Lv Xun Guo xin-ping Qiu Key Laboratory of Organic Optoelectronics and Molecular Engineering Department of ChemistryTsinghua University Be~iing 100084 China

We do a new Li-ion battery evaluation research on the effects of cell resistance and polariza- tion on the energy loss in batteries based on thermal property and heat generation behavior of battery. Series of 18650 cells with different capacities and electrode materials are evalu- ated by measuring input and output energy which change with charge-discharge time and current. Based on the results of these tests, we build a model of energy loss in cells＇ charge- discharge process, which include Joule heat and polarization heat impact factors. It was reported that Joule heat was caused by cell resistance, which included De-resistance and reaction resistance, and reaction resistance could not be easily obtained through routine test method. Using this new method, we can get the total resistance R and the polarization parameter U. The relationship between R, η, and temperature is also investigated in order to build a general model for series of different Li-ion batteries, and the research can be used in the performance evaluation, state of charge prediction and the measuring of consistency of the batteries.

关键词： Li-ion battery Energy loss Heat Cell resistance Polarization State of chargeprediction

Metallurgical Interpretation on Grain Refinement and Synergistic Effect of Mn and Ti in Ti-microalloyed Strip Produced by TSCR

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Journal of Iron and Steel Research International 2014年第1期21卷 30-40页

作者： xin-ping MAO Qi-lin CHEN xin-jun SUN College of Materials Science and Metallurgical Engineering Wuhan University of Science and Technology Institute of Structural Materials Central Iron and Steel Research Institute

The grain refinement mechanism and synergistic effect of Mn and Ti involved in the Ti-microalloying technology of thin slab casting and direct rolling （TSCR） were elucidated. Because the inevitable precipitation of TiN in high Ti-containing liquid steel decreases the volume fraction of TiN precipitated from austenite and the rapid coarse- ning rate leads to a large size of TiN particles, a relatively weak inhibition effect on the recrystallized grain growth was obtained compared with that in the low Ti-containing steel. However, the ferrite grain size in high Ti-containing steel can be refined by the so-called non-recrystallization rolling. The complex addition of Mn and Ti can improve the strength and toughness of strip remarkably, and the mechanisms are that Mn decreases the transformation tempera- ture, refines the ferrite grains, and enhances the formation of bainite and TiC precipitation in ferrite.

关键词： thin slab casting direct roiling TSCR Ti-microalloying grain refinement precipitation

A two-grid algorithm based on Newton iteration for the stream function form of the Navier-Stokes equations

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Applied Mathematics(A Journal of Chinese Universities) 2011年第3期26卷 368-378页

作者： SHAO xin-ping HAN Dan-fu Department of Mathematics Zhejiang University Hangzhou 310027 China

In this paper, we propose a two-grid algorithm for solving the stream function formulation of the stationary Navies-Stokes equations. The algorithm is constructed by reducing the original system to one small, nonlinear system on the coarse mesh space and two similar linear systems （with same stiffness matrix but different right-hand side） on the fine mesh space. The convergence analysis and error estimation of the algorithm are given for the case of conforming elements. Furthermore, the Mgorithm produces a numerical solution with the optimal asymptotic H^2-error. Finally, we give a numerical illustration to demonstrate the effectiveness of the two-grid algorithm for solving the Navier-Stokes equations.

关键词： Two-grid algorithm Navier-Stokes equations Stream function form Reynolds number Newton iteration.

Driving mechanisms of nitrogen transport and transformation in lacustrine wetlands

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Science China Earth Sciences 2016年第3期59卷 464-476页

作者： ZHAO Shan ZHOU Nian Qing SHEN xin ping Department of Hydraulic Engineering Tongji UniversityKey Laboratory of Yangtze River Water Environment Ministry of Education Shanghai 200092 China School of Civil and Environmental Engineering Georgia Institute of Technology Atlanta Georgia 30332 USA Dongting Lake Water Resources Administration Bureau of Hunan Province Changsha 410007 China

As an essential component of proteins and genetic material for all organisms, nitrogen(N) is one of the major limiting factors that control the dynamics, biodiversity and functioning of lacustrine wetlands, in which intensified N biogeochemical activities take place. Reactive N loaded into wetland ecosystems has been doubled due to various human activities, including industrial, agricultural activities and urbanization. The main driving mechanisms of N transport and transformation in lacustrine wetlands are categorized to pushing forces and pulling forces in this study. Geomorphology, wetland age, N concentrations, and temperature are the main pushing forces(passive forces); whereas water table variation, oxygen concentration, other elements availability, oxidation-reduction potential(Eh) and p H, and microorganisms are the predominant pulling forces(active forces). The direction and kinetic energy of reactions are determined by pulling forces and then are stimulated by pushing forces. These two types of forces are analyzed and discussed separately. Based on the analysis of driving mechanisms, possible solutions to wetland N pollutions are proposed at individual, regional and global scales, respectively. Additional research needs are addressed to obtain a thorough understanding of N transport and transformations in wetlands and to reduce detrimental impacts of excessive N on such fragile ecosystems.

关键词： Nitrogen Driving mechanisms Transport and transformation Excessive loading Lacustrine wetlands

A review of cavitation in tip-leakage flow and its control

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Journal of Hydrodynamics 2021年第2期33卷 226-242页

作者： Huai-yu Cheng Bin Ji xin-ping Long Wen-xin Huai Mohamed Farhat State Key Lab of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhan 430072China Hubei Key Laboratory of Waterjet Theory and New Technology Wuhan 430072China Laboratory for Hydraulic Machines Ecole Polytechnique Federale de Lausanne(EPFL)LausanneSwitzerland

The tip-leakage vortex(TLV)cavitation is a challenging issue for a variety of axial hydraulic turbines and pumps from both technical and scientific *** flow characteristics of the TLV cavitation were widely studied in the past decades,but the knowledge about the tip-leakage cavitating flow is still *** present paper reviews the progresses in the researches of the TLV cavitation,including the numerical methods for the TLV cavitation,the flow characteristics of the TLV,the influences of the TLV cavitation on the local flow field and the control strategies of the TLV *** is indicated that the non-condensable gas may play an important role in the development of the TLV cavitation,and this fact should be considered during a careful simulation of the TLV *** is also suggested that the development of the TLV cavitation will significantly influence the distributions of the vorticity and the turbulence kinetic *** to the complexity of the TLV cavitation,it is still an open question how to suppress the TLV cavitation in a simple but effective ***,based on these understandings,some advanced topics for the future work are suggested to further promote the study of the TLV cavitation,for a deeper knowledge about the TLV cavitation.

关键词： Cavitation tip-leakage vortex(TLV) cavitation model flow control nuclei

Gastrointestinal complications of systemic sclerosis

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World Journal of Gastroenterology 2013年第41期19卷 7062-7068页

作者： xin-ping Tian Xuan Zhang Department of Rheumatology Peking Union Medical College HospitalChinese Academy of Medical Sciences

Systemic sclerosis is an autoimmune disease characterized by progressive skin thickening and *** interstitial fibrosis and kidney damage are the most important indicators for mortality;however,the gastrointestinal tract is the most commonly damaged *** all parts of the gastrointestinal(GI)tract can be involved,although the esophagus is the most frequently *** mechanisms that cause such extensive damage are generally unclear,but vascular changes,immunological abnormalities,excessive accumulation of collagen in the submucosa,smooth muscle atrophy and neuropathy may participate because these are the most common histological findings in biopsies and *** patients with GI tract involvement complain about dyspepsia,nausea,vomiting,abdominal bloating/distension,and fecal *** symptoms are generally mild during the early stage of the disease and are likely ignored by *** the disease becomes more advanced,however,patient quality of life is markedly influenced,whereby malnutrition and shortened survival are the usual *** diagnosis for systemic sclerosis is based on manometry measurements and an endoscopy *** and symptomatic treatment is the main therapeutic strategy;however,an early diagnosis is critical for successful management.

关键词： Systemic sclerosis Gastrointestinal tract Manometry Endoscopy Diagnosis Treatment

Charge Transfer Channels in Formation of Exciplex in Polymer Blends

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Chinese Physics Letters 2011年第9期28卷 245-248页

作者： DOU Fei ZHANG xin-ping Institute of Information Photonics Technology and College of Applied Sciences Beijing University of TechnologyBeijing 100124

The strong dependence of photoluminescence of charge transfer excited states or exciplex in a blend film of poly(9,9'-dioctylfluorene-co-benzothiadiazole)(F8BT)and poly(9,9'-dioctylfluorene-co-bis-N,N'-(4-butylphenyl)-bis-N,N'-phenyl-l,4–phenylenediamine)(PFB)on the excitation wavelengths and morphology is *** experimental results reveal that electron transfer in the LUMOs from PFB to F8BT is more efficient than hole transfer in the HOMOs from PFB to F8BT for the formation of exciplex at the interfacial junctions between these two types of molecules in the blend ***,energy transfer from the blue-emitting PFB to the green-emitting F8BT at the interfaces introduces an additional two-step channel and thus enhances the formation of an *** is important for understanding of charge generation and separation in organic bulk heterojunctions and for design of optoelectronic devices.

关键词： film charge transfer

Edge-Fault-Tolerant Edge-Bipancyclicity of Bubble-Sort Graphs

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Acta Mathematica Sinica,English Series 2012年第4期28卷 675-686页

作者： xin ping XU Min XU Jin JING Jiangsu Institute of Education School of Mathematical Sciences Beijing Normal UniversityLaboratory of Mathematics and Complex SystemsMinistry of Education Department of Mathematics University of Science and Technology of China

The bubble-sort graph Bn is a bipartite graph. Kikuchi and Araki [Edge-bipancyclicity and edge-fault-tolerant bipancyclicity of bubble-sort graphs. Information Processing Letters, 100, 52- 59 （2006）] have proved that Bn is edge-bipancyclic for n ≤ 5 and Bn - F is bipancyclic when n ≥ 4 and IFI≤ n - 3. In this paper, we improve this result by showing that for any edge set F of Bn with IFI ≤ n - 3, every edge of Bn - F lies on a cycle of every even length from 6 to n! for n≤ 5 and every edge of Bn - F lies on a cycle of every even length from 8 to n! for n = 4.

关键词： Cycles bipancyclicity fault tolerance bubble-sort graph