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A statistic comparison of multi-element analysis of low atmospheric fine particles(PM_(2.5)) using different spectroscopy techniques

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Journal of Environmental sciences 2022年第4期34卷 194-203页

作者： Minkang Zhi Kai Zhang Xi Zhang Hartmut Herrmann Jian Gao Khanneh Wadinga Fomba Wei Tang Yuqian luo Huanhuan Li fan Meng State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China Faculty of Environmental Engineering The University of Kitakyushu1-1 HibikinoWakamatsuKitakyushuFukuoka 808-0135Japan atmospheric Chemistry Department(ACD) Leibniz-Institute for Tropospheric Research(TROPOS)Leipzig 04318Germany

Over the past few decades,the metal elements(MEs)in atmospheric particles have aroused great *** well-established techniques have been used to measure particlebound ***,each method has its own advantages and disadvantages in terms of complexity,accuracy,and specific elements of *** this study,the performances of inductively coupled plasma-optical emission spectrometry(ICP-OES)and total reflection X-ray fluorescence spectroscopy(TXRF)were evaluated for quality control to analyze data accuracy and *** statistic methods(Deming regression and significance testing)were applied for intercomparison between ICP-OES and TXRF measurements for same lowloading PM_(2.5)samples in Weizhou *** results from the replicate analysis of standard filters(SRM 2.83)and field filters samples indicated that 10 MEs(K,Ca,V,Cr,Mn,Fe,Ni,Cu,Zn,and Pb)showed good accuracies and precision for both *** higher accuracy tended to the higher precision in the MEs analysis *** addition,the interlab comparisons illustrated that V and Mn all had good agreements between ICP-OES and *** measurements of K,Cu and Zn were more reliable by TXRF analysis for low-loading PM_(2.5).ICP-OES was more accurate for the determinations for Ca,Cr,Ni and Pb,owing to the overlap{2. spectral lines and low sensitivity during TXRF *** measurements of Fe,influenced by low-loading PM_(2.5),were not able to determine which instrument could obtain more reliable *** conclusions could provide reference information to choose suitable instrument for the determination of MEs in low-loading PM_(2.5)samples.

关键词： Multielement analysis Low-loading fine particles Inductively coupled plasma-optical emission spectrometry Total reflection X-ray fluorescence spectroscopy Inter-laboratory comparison

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Paclitaxel and cisplatin with or without cetuximab in metastatic esophageal squamous cell carcinoma:a randomized,multicenter phase II trial

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The Innovation 2022年第3期3卷 65-71页

作者： Zhihao Lu Yanqiao Zhang Qingxia fan Yueyin Pan Da Jiang ping Lu Jingdong Zhang Xianglin Yuan Jifeng Feng Shujun Yang Wenbin Yue Lin Zhao Yunhua Xu Jinhua {2. Lin Shen Department of Gastrointestinal Oncology Peking University Cancer Hospital&InstituteBeijing 100142China Department of Gastrointestinal Medical Oncology Harbin Medical University Cancer HospitalHarbin 150081China Department of Oncology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Oncology Anhui Province HospitalHefeiAnhui 230088China Department of Medical Oncology the Fourth Hospital of Hebei Medical UniversityShijiazhuangHebei Province 050011China Department of Medical Oncology First Affiliated Hospital of Xinxiang Medical UniversityXinxiangHenan 453199China Medical Oncology Department of Gastrointestinal Cancer Liaoning Cancer Hospital&InstituteCancer Hospital of China Medical UniversityShenyang 110042China Department of Oncology Tongji HospitalHuazhong University of Science and TechnologyWuhanHubei 430030China Department of Oncology Jiangsu Cancer HospitalNanjingJiangsu 210009China Department of Medical Oncology Affiliated Cancer Hospital of Zhengzhou UniversityHenan Cancer HospitalZhengzhouHenan 450003China Department of Oncology Puyang Oilfield General Hospital PuyangHenanChina Department of Medical Oncology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China Department of Shanghai Lung Cancer Center Shanghai Chest HospitalShanghai Jiao Tong UniversityShanghai 200030China Department of Thoracic Surgery Jiangsu Province Hospitalthe First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China

Lack of effective targeted therapy in metastatic esophageal squamous cell carcinoma(ESCC)underscores the urgent need for identifying new treatment approaches for this challenging *** sought to assess the addition of cetuximab to paclitaxel-cisplatin chemotherapy for first-line treatment in patients with metastatic *** this randomized,multicenter,open-label,phase II clinical trial,patients were randomized to receive paclitaxel-cisplatin(TP)(paclitaxel[175 mg/m^(2. intravenously(i.v.)on day 1 of every 3-week cycle]and cisplatin[75 mg/m^(2. *** day 1 of every 3-week cycle])and TP plus cetuximab(CTP)(cetuximab,400 mg/m^(2. *** day 1 of week 1,followed by 2.0 mg/m^(2. weekly).

关键词： cetuximab chemotherapy treatment

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Simulation of the western North Pacific subtropical high in El Ni?o decaying summers by CMIP5 AGCMs

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atmospheric and Oceanic Science Letters 2017年第2期10卷 146-155页

作者： DONG Xiao fan fang-Xing LIN Ren-{2. JIN Jiang-Bo LIAN Ru-Xu International Center for Climate and Environment sciences Institute of Atmospheric Physics Chinese Academy of Sciences Beijing China

The performances of CMIP5 atmospheric general circulation models （AGCMs） in simulating the western North Pacific subtropical high （WNPSH） in El Nino decaying summers are examined in this study. Results show that most models can reproduce the spatial pattern of both climatological and anomalous circulation associated with the WNPSH in El Nino decaying summers. Most CMIP5 AGCMs can capture the westward shift of the WNPSH in El Nino decaying summers compared with the climatological location. With respect to the sub-seasonal variation of the WNPSH, the performances of these AGCMs in reproducing the northward jump of the WNPSH are better than simulating the eastward retreat of the WNPSH from July to August. Twenty-one out of twenty-two （2. out of 2.） models can reasonably reproduce the northward jump of the WNPSH in El Nino decaying summers （climatology）, while only 7 out of 2. （8 out of 2.） AGCMs can reasonably reproduce the eastward retreat of the WNPSH in El Nino decaying summers （climatology）. In addition, there is a close connection between the climatological WNPSH location bias and that in El Nino decaying summers.

关键词： Western North Pacific subtropical high El Nino decaying summer CMIPS AGCM sub-seasonal variation

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Effects of Northern Hemisphere Annular Mode on terrestrial near-surface wind speed over eastern China from 1979 to 2.17

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Advances in Climate Change Research 2022年第6期13卷 875-883页

作者： Jin-Lin ZHA Cheng SHEN Jian WU De-Ming ZHAO Wen-Xuan fan Hui-ping JIANG Cesar AZORIN-MOLINA Deliang CHEN Key Laboratory of atmospheric Environment and Processes in the Boundary Layer Over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunming 650091China Key Laboratory of Regional Climate and Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Regional Climate Group Department of Earth SciencesUniversity of GothenburgGothenburg 004631Sweden International Research Center of Big Data for Sustainable Development Goals(CBAS) Beijing 100094China Key Laboratory of Digital Earth Science Aerospace Information Research Institute(AIR)Chinese Academy of SciencesBeijing 100094China Centro de Investigaciones Sobre Desertificación Consejo Superior de Investigaciones Científicas(CIDE-CSIC)Moncada Valencia 46008Spain

Large-scale ocean‒atmosphere circulations(LOACs)have a pronounced effect on the near-surface wind speed(NSWS).In this study,we discussed the contributions of zonal and meridional flows to NSWS changes and identify the possible association between the Northern Hemisphere Annular Mode(NAM)and the NSWS changes over eastern China from 1979 to *** show that the reduction in NSWS over eastern China was mainly dominated by the weakening of the zonal wind *** has a considerable effect on the NSWS over eastern *** the NAM exhibits positive phases,the zonal-mean westerly weakens at low-to-mid-latitudes(10°-40°N).Meanwhile,descending flows prevail near 40°N,and ascending flows persist near 65°N in the *** the lower troposphere,there are northerly anomalies at low-to-mid-latitudes and southerly anomalies at mid-to-high latitudes(40°-70°N).The anomalous meridional flows transport heat from low to high latitudes and weaken the north‒south air temperature *** decreased air temperature gradient over East Asia reduces the pressure gradient near the surface,decreasing NSWS in eastern *** variations could dominate(32.0±15.8)%of the changes in the annual mean ***,the contribution of NAM to the interannual changes of the zonal component in NSWS could reach(45.0±12.9)%.

关键词： Near-surface wind speed Temperature gradient Pressure gradient Northern Hemisphere Annular Mode Large-scale ocean-atmosphere circulations

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EEA algorithm model in estimating spread and evaluating countermeasures on high performance computing

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Journal of Biomedical Science and Engineering 2009年第1期2卷 41-50页

作者： Si-Yuan Liu Chao Liu Yu Liu Yi-Ming luo Gao-Jin Wen Jian-ping {2. Hong Kong University of Science and Technology Hong Kong China institute of Computing Technology Chinese Academy of Sciences Beijing China Royal institute of Technology Stockholm Sweden Shenzhen institute of Advanced Technology Chinese Academy of Sciences Shenzhen China

This work started out with the in-depth feasibil-ity study and limitation analysis on the current disease spread estimating and countermea-sures evaluating models, then we identify that the population variability is a crucial impact which has been always ignored or less empha-sized. Taking HIV/AIDS as the application and validation background, we propose a novel al-gorithm model system, EEA model system, a new way to estimate the spread situation, evaluate different countermeasures and analyze the development of ARV-resistant disease strains. The model is a series of solvable ordi-nary differential equation (ODE) models to es-timate the spread of HIV/AIDS infections, which not only require only one year’s data to deduce the situation in any year, but also apply the piecewise constant method to employ multi- year information at the same time. We simulate the effects of therapy and vaccine, then evaluate the difference between them, and offer the smallest proportion of the vaccination in the population to defeat HIV/AIDS, especially the advantage of using the vaccination while the deficiency of using therapy separately. Then we analyze the development of ARV-resistant dis-ease strains by the piecewise constant method. Last but not least, high performance computing (HPC) platform is applied to simulate the situa-tion with variable large scale areas divided by grids, and especially the acceleration rate will come to around 4 to 5.5.

关键词： EEA ODE HIV/AIDS Spread Estimating Countermeasure Evaluation High Performance Computing

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The In-Flight Realtime Trigger and Localization Software of GECAM

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Research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： Xiao-Yun Zhao Shao-Lin Xiong Xiang-Yang Wen Xin-Qiao Li Ce Cai Shuo Xiao Qi luo Wen-Xi Peng Dong-Ya Guo Zheng-Hua An Ke Gong Jin-Yuan Liao Yan-Qiu Zhang Yue Huang Lu Li Xing Wen Fei Zhang Jing Duan Chen-Wei Wang Dong-Li Shi Peng Zhang Qi-Bin Yi Chao-Yang Li Yan-Bing Xu Xiao-Hua Liang Ya-Qing Liu Da-Li Zhang Xi-Lei Sun fan Zhang Gang Chen Huan-Yu Wang Sheng Yang Xiao-Jing Liu Min Gao Mao-Shun Li Jin-Zhou Wang Xing Zhou Yi Zhao Wang-Chen Xue Chao Zheng Jia-Cong Liu Xing-Bo Han Jin-Ling Qi Jia Huang Ke-Ke Zhang Can Chen Xiong-Tao Yang Dong-Jie Hou Yu-Sa Wang Rui Qiao Xiang Ma Xiao-Bo Li {2. Wang Xin-Ying Song Li-Ming Song Shi-Jie Zheng Bing Li Hong-Mei Zhang Yue Zhu Wei Chen Jian-Jian He Zhen Zhang Jin Hou Hong-Jun Wang Yan-Chao Hao Xiang-Yu Wang Zong-Yuan Yang Zhi-Long Wen Zhi Chang Yuan-Yuan Du Rui Gao Xiao-Fei Lan Yan-Guo Li Gang Li Xu-fang Li fang-Jun Lu Hong Lu Bin Meng Feng Shi Hui Wang Hui-Zhen Wang Yu-Peng Xu Jia-Wei Yang Xue-Juan Yang Shuang-Nan Zhang Chao-Yue Zhang Cheng-Mo Zhang Zhi-Cheng Tang Cheng Cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of chinese academy of sciences Chinese Academy of SciencesBeijing 100049China School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar physics and Department of physics Xiangtan UniversityXiangtan 411105China physics and Space Science College China West Normal UniversityNanchong 637002China Department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation academy for Microsatellites of CAS Shanghai 201203China Changchun University of Science and Technology Changchun 130022China chinese academy of {2. South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2.2. December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

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Upper-tropospheric potential vorticity anomaly before the rapid intensification of Typhoon Mujigae(2.15)and its response to reduced SST

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atmospheric and Oceanic Science Letters 2020年第5期13卷 390-399页

作者： TANG Xiba YANG Shuai ping fan PENG Jing Laboratory of Cloud-Precipitation physics and Severe Storms Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina

As the strongest typhoon in 2.15,the rapid intensification(RI)process of Typhoon Mujigae is simulated at the cloud-resolving scale by utilizing the Weather Research and Forecasting model,coupled with observed sea surface temperature(SST)and reduced SST as the control and sensitivity experiments,*** spatiotemporal distribution characteristics of uppertropospheric potential vorticity(PV)and its response to SST changes are analyzed *** results show a significant upper-tropospheric PV anomaly 6 h before RI,which indicates the approaching RI of Typhoon *** convection overlies the strong signals of upper-tropospheric PV *** insight into the PV budget analysis verifies that the diabatic heating effect and vertical advection terms associated with deep convection dominate the upper-tropospheric PV anomaly,inferring that deep convection plays a crucial role in the upper-tropospheric PV *** SST decreases,diabatic heating and vertical advection effects are weakened due to reduced deep convection;therefore,the PV anomaly in the model run is not stronger than that in the control run,and the RI process of Mujigae ***,from the viewpoint of upper and lower-level interactions,how SST impacts upper-tropospheric PV anomalies and their interactions with RI are ***,in addition to SST,the upper-tropospheric PV anomaly might be a significant factor in differentiating between RI and non-RI tropical cyclones.

关键词： Upper-tropospheric potential vorticity typhoon rapid intensification

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垂直分辨率对广州“5·7”特大暴雨数值模拟影响的研究

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大气科学 2019年第6期43卷 1245-1264页

作者：王宁平凡南京信息工程大学遥感与测绘工程学院南京210044 中国科学院大气物理研究所云降水物理与强风暴重点试验室(LACS) 北京100029

精细化的垂直分辨率能够更好地反映大气动热力环境和中尺度系统生消演变过程,不同层次高度垂直分辨率的加密对暖区对流系统触发及组织发展机制的影响有待深入研究。本文针对2.17年5月6日(UTC)广州局地突发的特大暴雨受复杂地形影响、其... 详细信息

精细化的垂直分辨率能够更好地反映大气动热力环境和中尺度系统生消演变过程,不同层次高度垂直分辨率的加密对暖区对流系统触发及组织发展机制的影响有待深入研究。本文针对2.17年5月6日(UTC)广州局地突发的特大暴雨受复杂地形影响、其对流中尺度系统局地触发、后向传播及组织化的特点,运用WRFV3.9.1,采用GFS资料较好地模拟和再现了此次大暴雨过程,并进行了不同高度垂直分辨率的敏感性试验,以探究垂直分辨率对此次暖区暴雨触发及组织化过程的影响。结果表明:低层垂直分辨率加密试验能够模拟出更强的偏南回流、偏东风和较强的低层风场辐合以及较强的温度扰动,进而引起更强的对流触发;中层垂直分辨率加密更有利于大范围的强干冷空气侵入对流系统,其造成的潜热和不稳定能量的释放,是对流系统发展的重要原因;高空垂直分辨率的加密试验则描述出了对流系统上部与高空急流出流相关的高空辐散中心、对流系统周围的高空强辐散中心以及相邻对流单体的垂直环流,细致再现了对流单体合并为对流系统的组织化过程。

关键词：垂直分辨率暖区暴雨复杂地形对流触发对流组织化

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Characteristics of complex air pollution in typical cities of North China

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atmospheric and Oceanic Science Letters 2018年第1期11卷 29-36页

作者： TANG Bin-Yan XIN Jin-Yuan GAO Wen-Kang SHAO ping SU Hong-Juan WEN Tian-Xue SONG tao fan Guang-Zhou WANG Shi-Gong plateau Atmosphere and Environment Key Laboratory of Sichuan Province ＆ College of atmospheric sciences Chengdu University of Information Technology Chengdu China State Key Laboratory of atmospheric Boundary Layer physics and atmospheric Chemistry Institute of Atmospheric Physics Chinese Academy of Sciences Beijing China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science ＆Technology Nanjing China

The beijing-Tianjin-Hebei urban agglomeration is currently facing severe complex air pollution. In this paper, simultaneous observations conducted in 2.14 show that the annual mean concentration of fine particulate matter （PM2.5） was 84 ± 70, 86 ±60, and 118 ± 95 μg m-3 in beijing, Tianjin, and Shijiazhuang, respectively. The mean 03 8h max in the summer was 171 ± 43, 147 ± 45, and 146 ± 44 μg m-3, respectively. This research indicates that PM2.5 and O3 are positively correlated when the temperature exceeds 2. ℃5 and the urban agglomeration shows characteristics of complex air pollution consisting of superimposed 03 and PM2.s. In summer, when the humidity was less than 55%, secondary particles and 03 also increased in a coordinated manner （y = 1.35x ＋ 2..85; R2.= 0.61）, which demonstrates severe complex pollution. However, the mean PM2.5（y） and mean 03 8 h max （x） in summer showed a negative correlation （y = - 1.3x ＋ 2.5; R2.= 0.61 ） in the three regions, indicating high concentrations of PM2.5 pollution partially inhibit O3 generation.

关键词： O3 PM2.5 PM10 complex airpollution beijing-Tianjin-Hebei urban agglomeration

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The impact of the atmospheric turbulence-development tendency on new particle formation: a common finding on three continents

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National Science Review 2021年第3期8卷 140-150页

作者： Hao Wu Zhanqing Li Hanqing Li Kun luo Yuying Wang Peng Yan Fei Hu fang Zhang Yele Sun Dongjie Shang Chunsheng Liang Dongmei Zhang Jing Wei Tong Wu Xiaoai Jin Xinxin fan Maureen Cribb Marc L.Fischer Markku Kulmala Tuukka Pet?j? State Key Laboratory of Remote Sensing Science College of Global Change and Earth System ScienceBeijing Normal University ESSIC and Department of atmospheric Science University of MarylandCollege Park State Key Laboratory of Clean Energy Utilization Zhejiang University School of atmospheric physics Nanjing University of Information Science and Technology Meteorological Observation Center China Meteorological Administration State Key Laboratory of atmospheric Boundary Layer physics and atmospheric Chemistry Institute of Atmospheric Physics Chinese Academy of Sciences State Key Joint Laboratory of Environmental Simulation and Pollution Control College of Environmental Sciences and Engineering Peking University State Key Joint Laboratory of Environment Simulation and Pollution Control School of Environment Tsinghua University Lawrence Berkeley National Laboratory institute for atmospheric and Earth System Research/{2. Faculty of ScienceUniversity of Helsinki Aerosol and Haze Laboratory Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Joint International Research Laboratory of atmospheric and Earth System sciences School of Atmospheric Sciences Nanjing University

A new mechanism of new particle formation(NPF) is investigated using comprehensive measurements of aerosol physicochemical quantities and meteorological variables made in three continents,including beijing,China;the Southern Great Plains site in the USA;and SMEAR Ⅱ Station in Hyytiala,Finland.D espite the considerably different emissions of chemical species among the sites,a common relationship was found between the characteristics of NPF and the stability *** stability parameter(ζ=Z/L,where Z is the height above ground and L is the Monin-Obukhov length) is found to play an important role;it drops significantly before NPF as the atmosphere becomes more unstable,which may serve as an indicator of nucleation *** the atmosphere becomes unstable,the NPF duration is closely related to the tendency for turbulence development,which influences the evolution of the condensation ***,the unstable atmosphere may dilute pre-existing particles,effectively reducing the condensation sink,especially at coarse mode to foster *** new mechanism is confirmed by model simulations using a molecular dynamic model that mimics the impact of turbulence development on nucleation by inducing and intensifying homogeneous nucleation events.

关键词： new particle formation turbulence development molecular dynamic

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