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Direct writing of silver microfiber with precise control on patterning for robust and flexible ultrahigh-performance transparent conductor

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Journal of Materials Science & Technology 2020年第12期47卷 103-112页

作者： Tao Chen Heping Li Jing Li Sanyuan Hu pin ye Youwei Yan State Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

Ultrafine silver fiber is an alternative to commercial indium tin oxide(ITO) as a new-generation flexible transparent conductor that can be used in flexible ***,its primary limitation is the unrepeatable optoelectronic properties due to the disordered distribution of silver *** this work,we report the in-situ direct writing of the silver microfiber pattern with high conductivity and transparency to attain a flexible transparent *** silver network is composed of silver microfibers,which can be artificially designed and regularly patterned under the precise control of the fiber position and shape;this is crucial for regulating its optoelectronic ***,a high-performance conductor is achieved in the silver network with high *** novel conductor has a sheet resistance of 2 Ω sq-1at 90% transparency,which corre sponds to a high Figure of merit σdc/σopt=*** in-situ direct writing technique developed here is distinct from other fabrication methods because it requires no transfer steps,templates or ***,this silver network is integrated into a light-printable rewritable device,and can be used as a wearable heater;this heater when driven by a 1.5 V battery attains a temperature of up to 55.6℃.Therefore,in-situ direct writing is expected to offer a new platform for facile,scalable,and ultralow-cost production of high-performance metal networks for flexible transparent conductors.

关键词： Silver Transparent conductor Direct writing Patterning Transparent heater

Scorpion toxin BmKI directly activates Nav1.8 in primary sensory neurons to induce neuronal hyperexcitability in rats

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Protein & Cell 2015年第6期6卷 443-452页

作者： pin ye Yunlu Jiao Zhenwei Li Liming Hua Jin Fu Feng Jiang Tong Liu Yonghua Ji Laboratory of Neuropharmacology and Neurotoxicology Shanghai University Shanghai 200436 China Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases and the Second Affiliated Hospital of Soochow University Institute of Neuroscience Soochow University Suzhou 215021 China

Voltage-gated sodium channels （VGSCs） in primary sensory neurons play a key role in transmitting pain signals to the central nervous system. BmK I, a site-3 sodium channel-specific toxin from scorpion Buthus martensi Karsch, induces pain behaviors in rats. How- ever, the subtypes of VGSCs targeted by BmK I were not entirely clear. We therefore investigated the effects of BmK I on the current amplitude, gating and kinetic properties of Nav1.8, which is associated with neuronal hyperexcitability in DRG neurons. It was found that BmK I dose-dependently increased Nav1.8 current in small- sized （〈25 μm） acutely dissociated DRG neurons, which correlated with its inhibition on both fast and slow in- activation. Moreover, voltage-dependent activation and steady-state inactivation curves of Nay1.8 were shifted in a hyperpolarized direction. Thus, BmK I reduced the threshold of neuronal excitability and increased action potential firing in DRG neurons. In conclusion, our data clearly demonstrated that BmK I modulated Nav1.8 re- markably, suggesting BmK I as a valuable probe for studying Nay1.8. And Navl.8 is an important target re- lated to BmK I-evoked pain.

关键词： voltage-gated sodium channel Nay1.8,primary sensory neurons BmK I

Current Status and Prospect of Stent Placement for May-Thurner Syndrome

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Current Medical Science 2021年第6期41卷 1178-1186页

作者： Qin LIU Fang LIU ping LÜ Hong-xiao WU pin ye Yun YOU Zhong YAO Department of Vascular Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Nuclear Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Donnelly Centre for Cellular and Biomolecular Research University of TorontoTorontoOntario M5S 2E8Canada

Stent implantation has been proven to be safe and has become the first-line intervention for May-Thumer syndrome(MTS),with satisfactory mid-term patency rates and clinical *** research has demonstrated that catheter-directed thrombolysis is the preferred strategy when MTS is combined with deep vein thrombosis after self-expanding stent ***,the stent used for the venous system was developed based on the experience obtained in the treatment of arterial ***,relatively common corresponding complications may come along later,which include stent displacement,deformation,and *** measures such as adopting a stent with a larger diameter,improving stent flexibility,and increasing stent strength have been employed in order to prevent these *** ideal venous stent is presently being evaluated and will be introduced in detail in this review.

关键词： May-Thumer syndrome deep vein thrombosis post-thrombotic syndromes stent stent placement

Influence of coronal holes on CMEs in causing SEP events

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Research in Astronomy and Astrophysics 2010年第10期10卷 1049-1060页

作者： Cheng-Long Shen Jia Yao Yu-Ming Wang pin-Zhong ye Xue-Pu Zhao Shui Wang CAS Key Laboratory of Basic Plasma Physics School of Earth and Space Sciences University of Science and Technology of China Hefei 230026 China State Key Laboratory of Space Weather Chinese Academy of Science Beijing 100080 China W. W. Hansen Experimental Physics Laboratory Stanford University Stanford CA 94305 USA

The issue of the influence of coronal holes （CHs） on coronal mass ejections （CMEs） in causing solar energetic particle （SEP） events is revisited. It is a continuation and extension of our previous work, in which no evident effects of CHs on CMEs in generating SEPs were found by statistically investigating 56 CME events. This result is consistent with the conclusion obtained by Kahler in 2004. We extrapolate the coronal magnetic field, define CHs as the regions consisting of only open magnetic field lines and perform a similar analysis on this issue for 76 events in total by extending the study interval to the end of 2008. Three key parameters, CH proximity, CH area and CH relative position, are involved in the analysis. The new result confirms the previous conclusion that CHs did not show any evident effect on CMEs in causing SEP events.

关键词： acceleration of particles -- Sun coronal mass ejections -- Sun coronal holes -- Sun particle emission

Activation of mammalian target of rapamycin contributes to pain nociception induced in rats by BmK I, a sodium channel-specific modulator

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Neuroscience Bulletin 2014年第1期30卷 21-32页

作者： Feng Jiang Li-Ming Hua Yun-Lu Jiao pin ye Jin Fu Zhi-Jun Cheng Gang Ding Yong-Hua Ji Xinhua Hospital (Chongming) Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Chongming Xinhua Translational Medical Institute for Cancer Pain Lab of Neuropharmacology and Neurotoxicology Shanghai University

The mammalian target of rapamycin （mTOR） pathway is essential for maintenance of the sensitivity of certain adult sensory neurons. Here, we investigated whether the mTOR cascade is involved in scorpion envenomation-induced pain hypersensitivity in rats. The results showed that intraplantar injection of a neurotoxin from Buthus martensii Karsch, BmK I （10 pg）, induced the activation of mTOR, as well as its downstream molecules p70 ribosomal S6 protein kinase （p70 S6K） and eukaryotic initiation factor 4E-binding protein 1 （4E-BP1）, in lumbar 5-6 dorsal root ganglia neurons on both sides in rats. The activation peaked at 2 h and recovered 1 day after injection. Compared with the control group, the ratios of p-mTOR/p-p70 S6K/p-4E- BP1 in three types of neurons changed significantly. The cell typology of p-mTOR/p-p70 S6K/p-4E-BP1 immuno-reactive neurons also changed. Intrathecal administration of deforolimus, a specific inhibitor of mTOR, attenuated BmK I-induced pain responses （spontaneous flinching, paroxysmal pain-like behavior, and mechanical hypersensitivity）. Together, these results imply that the mTOR signaling pathway is mobilized by and contributes to experimental scorpion sting-induced pain.

关键词： BmK I mTOR p70 ribosomal S6 protein kinase 4E-binding protein 1 pain dorsal rootganglion

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基于误差传播理论的PnP问题姿态精度分析

光学精密工程 2019年第2期27卷 479-487页

作者：屈也频侯旺海军研究院上海200436

提出了一种在辨识一组典型特征点误差关系的基础上,建立间接测量值与直接测量值之间的最有利函数关系,并根据误差传播理论综合其他特征点的误差影响,最终获得完整的方位、俯仰和倾斜角误差数学模型的PnP问题误差分步分析新方法。以P4P... 详细信息

提出了一种在辨识一组典型特征点误差关系的基础上,建立间接测量值与直接测量值之间的最有利函数关系,并根据误差传播理论综合其他特征点的误差影响,最终获得完整的方位、俯仰和倾斜角误差数学模型的PnP问题误差分步分析新方法。以P4P问题研究为例,推导得到了单目视觉测量中相关参数和变量的误差函数解析式,揭示了影响姿态测量精度的误差规律。经P4P姿态解算仿真,验证了误差数学模型的正确性,以及基于误差传播理论的误差分步方法的有效性。分析误差数学模型可以看出:在单目视觉测量参数确定的条件下,方位角测量误差与方位角值无关,与相机高度和合作标志尺寸的比值成正比,在较大范围内俯仰和倾斜角变化对方位角测量误差影响小;俯仰/倾斜角的测量误差与俯仰/倾斜角值有关,与相机高度和合作标志尺寸比值的平方成正比;方位角测量误差小于俯仰/倾斜角测量误差。给出的分析方法和误差解析数学模型对单目视觉测量系统设计有指导作用。

关键词：单目视觉测量 PnP问题精度分析误差传播姿态间接测量

基于DEA的搜潜方案评估及输出量的模糊偏好修正

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系统工程与电子技术 2008年第10期30卷 1883-1886页

作者：屈也频廖瑛国防科技大学航天材料与工程学院湖南长沙410073 海军装备研究院规范所上海200233

运用带有偏好锥的DEA方法,研究了反潜巡逻飞机搜索方案评估和决策应用模型。特别是针对决策单元输出为概率指标以及决策者对搜索发现概率偏好程度具有一定模糊性的情况,引入模糊隶属度函数概念,提出了一种可体现决策者意愿的输出量的模... 详细信息

运用带有偏好锥的DEA方法,研究了反潜巡逻飞机搜索方案评估和决策应用模型。特别是针对决策单元输出为概率指标以及决策者对搜索发现概率偏好程度具有一定模糊性的情况,引入模糊隶属度函数概念,提出了一种可体现决策者意愿的输出量的模糊偏好修正方法,使DEA评估结果既具有较强的客观性,又充分尊重决策者的主观意愿。最后给出了评估算例,验证了模型的合理性,可应用于反潜巡逻飞机搜潜方案的计算机辅助决策。

关键词：数据包络分析搜索方案模糊偏好修正偏好锥反潜战

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潜艇位置散布规律与搜潜效能评估模型研究

系统仿真学报 2008年第12期20卷 3280-3283,3289页

作者：屈也频廖瑛国防科技大学航天材料与工程学院长沙410073 海军装备研究院规范所上海200233

针对当前搜潜效能评估中对潜艇位置的假设存在不合理的情况,提出了执行巡逻搜索和应召搜索任务时的潜艇位置散布模型,在此基础上,建立了声纳浮标阵搜潜概率的评估模型,并采用计算机仿真评估方法证明了模型的正确性,计算结果也表明对潜... 详细信息

针对当前搜潜效能评估中对潜艇位置的假设存在不合理的情况,提出了执行巡逻搜索和应召搜索任务时的潜艇位置散布模型,在此基础上,建立了声纳浮标阵搜潜概率的评估模型,并采用计算机仿真评估方法证明了模型的正确性,计算结果也表明对潜搜索评估结果与潜艇位置的散布规律假设密切相关,必须根据情况合理地选择模型。

关键词：应召反潜搜索巡逻反潜搜索搜索概率效能评估模型声纳浮标反潜战

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心肾综合征的研究进展

中华老年医学杂志 2010年第3期29卷 180-183页

作者：叶平解放军总医院心内科北京100853

随着人口老龄化进程加速，心力衰竭（心衰）发病人数逐年增加，同时，随着对慢性肾脏疾病认识的深入，终末期肾病乃至轻度、中度肾功能不全的发病率均显著升高。引起动脉粥样硬化的糖尿病、脂代谢异常、高血压和高尿酸血症，已经成为心... 详细信息

随着人口老龄化进程加速，心力衰竭（心衰）发病人数逐年增加，同时，随着对慢性肾脏疾病认识的深入，终末期肾病乃至轻度、中度肾功能不全的发病率均显著升高。引起动脉粥样硬化的糖尿病、脂代谢异常、高血压和高尿酸血症，已经成为心衰和慢性肾脏疾病的共同病因。当心衰与肾衰竭共存时即为心肾综合征（CRS），二者相互作用，互为因果，产生叠加、放大的病理损害效应，进一步加速了多器官功能衰竭，病死率增加。

关键词：心肾综合征慢性肾脏疾病中度肾功能不全多器官功能衰竭动脉粥样硬化人口老龄化终末期肾病脂代谢异常