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Science China Chem.stry 2024年第4期67卷 1097-1116页

作者： Li Yuan Yi-pin Zhang You-Xuan Zheng State Key Laboratory of Coordination Chem.stry Collaborative Innovation Center of Advanced MicrostructuresJiangsu Key Laboratory of Advanced Organic MaterialsSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China

Chirality is an im.ortant natural characteristic of organic m.lecules,and chiral organic m.lecules have shown extensive application in areas such as pharm.ceutical developm.nt and m.terial *** from.the ability to achieve circularly polarized lum.nescence(CPL),chiral lum.nescent m.terials have shown potential applications in anti-glare display,optical com.unication and,3D display,*** to the ability to harvest both singlet and triplet excitons by a fast reverse intersystem.crossing process without involving noble m.tals,chiral therm.lly activated delayed fluorescence(TADF)m.terials with point chirality,axial chirality,planar chirality and helical chirality are regarded as the state-of-the-art m.terials for circularly polarized organic light-em.tting diodes(CP-OLEDs).In recent years,the chiral TADF m.terials and CP-OLEDs have rapidly developed,but unfortunately,the dissym.etry factors(g)are far from.the requirem.nt of practical *** ideal em.tters and devices should have both high efficiency and a g factor,or at least a balance between these two *** review gives an overview of recent progress in chiral TADF m.terials,with a particular focus on the chiral skeleton,CPL property and device ***,the m.lecular design concept,device structure and m.thods to im.rove the g factors of chiral m.terials and CP-OLEDs are also discussed.

关键词： chiral therm.lly activated delayed fluorescence m.terial chiral skeleton circularly polarized lum.nescence circularly polarized organic light-em.tting diodes dissym.etry factor

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Im.act Perform.nce Research of Re-Entrant Octagonal Negative Poisson’s Ratio Honeycom. with Gradient Design

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Com.uter m.deling in Engineering & Sciences 2024年第9期140卷 3105-3119页

作者： Yiyuan Li Yongjing Li Shilin Yan pin Wen Departm.nt of Engineering Structure and m.chanics Wuhan University of TechnologyWuhan430070China Hubei Key Laboratory of Theory and Application of Advanced m.terials m.chanics School of ScienceWuhan University of TechnologyWuhan430070China

Based on the traditional re-entrant honeycom.,a novel re-entrant octagon honeycom.(ROH)is *** deform.tion m.de of the honeycom. under quasi-static com.ression is analyzed by num.rical sim.lation,and the results are in good agreem.nt with the experim.ntal *** deform.tion m.des,m.chanical properties,and energy absorption characteristics of ROH along the im.act and perpendicular directions gradient design are investigated under different *** results indicated that the deform.tion m.de of ROH is affected by gradient design along the direction of im.act and im.act *** addition,gradient design along the direction of im.act can increase the initial peak stress of ROH and accelerate its densification *** design perpendicular to the im.act direction can enhance the energy absorption perform.nce of ROH,especially for ROH,with wall thickness increasing from.the inside *** to ROH with uniform.wall thickness at the sam. relative density,ROH with a gradient design can increase the plateau stress by over *** the elevation of im.act velocity,the plateau stress and specific energy absorption exhibit an upward trend,aligning with the dynam.c perform.nce pattern observed in conventional *** results can be used as a reference for the design and application of honeycom. and provide a new idea for developing m.re efficient and reliable energy-absorbing m.terials.

关键词： Re-entrant honeycom. gradient design finite elem.nt analysis additive m.nufacturing technologies

Inform.ng policy m.kers in developing countries:Practices and lim.tations of geriatric hom. m.dication review in m.laysia-A qualitative inquiry

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Asian Pacific Journal of Tropical m.dicine 2024年第1期17卷 21-29,I0001-I0003页

作者： Ahlam.Sundus Renukha Sellappans Tan m.w pin Kulliyyah of Pharm.cy International Islamic University MalaysiaJalan Sultan Ahmad ShahKuantanPahangMalaysia School of Pharm.cy Faculty of Health and Medical SciencesTaylor’s UniversitySubang JayaSelangorMalaysia Departm.nt of m.dicine Faculty of MedicineUniversity of MalayaKuala LumpurMalaysia

Objective:To explore existing practices and challenges in the delivery of geriatric hom. m.dication review(Hm.).The study was part of a larger study aim.d to offer solution to expand the range of geriatric ***:This study em.loyed qualitative exploratory design through sem.-structured individual in-depth interviews with the public pharm.cists involved in the delivery of geriatric Hm. at public *** purpose of the interviews was to explore challenges faced by them.in the delivery of geriatric ***:Based on the em.rging them.s from.the qualitative data,the study reveals that geriatric Hm. in m.laysia is integrated as part of m.ltidisciplinary hom. care visits,encom.assing a diverse patient population with various healthcare ***,it faces challenges such as the lack of outcom. m.nitoring,form.l training,and workforce *** these hurdles,there is a pressing need for the expansion of this service to better serve the com.unity,and collaboration with com.unity pharm.cists holds potential to broaden its ***,the findings suggest that pharm.cist-led Hm. is both warranted and feasible within the m.laysian healthcare *** order to optim.ze m.dicine-use am.ng older people living in the com.unity,approaches for expanding geriatric Hm. services in m.laysia m.st be ***:This study holds profound im.lications as it attem.ts to illum.nate policy m.kers in developing countries,enabling them.to form.late effective Hm. *** considering the challenges highlighted within this research,policy m.kers can design a com.rehensive Hm. service that caters adeptly to the healthcare needs of the m.ss population.

关键词： Hom. m.dication review Older adults m.laysia Pharm.cists Low-to-m.ddle-incom. countries

Im.act wear properties of dissim.lar joints between bainitic frogs and pearlite rails

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Journal of Iron and Steel Research International 2024年第1期31卷 275-287页

作者： pin-yong Zeng Chun-guang Zuo Xiao-yu Zhang Wei Li Tribology Research Institute Southwest Jiaotong UniversityChengdu610031SichuanChina

The im.act wear behavior and dam.ge m.chanism.of dissim.lar welded joints between U26m. frog and U75 V rail before and after norm.lizing treatm.nt were studied by cyclic im.act *** experim.nt indicated that the im.act wear volum. of the joints increased with the increasing num.er of im.act *** m.in wear m.chanism. include pitting wear,m.ld fatigue wear,delam.nation wear,and fatigue wear,and plastic deform.tion was the prim.ry im.act wear *** them.fatigue wear had the greatest influence on wear volum.,while other wear m.chanism. had lim.ted *** im.act wear resistance of the base m.terial was better than that of the heat-affected *** treatm.nt was beneficial to im.roving the im.act wear resistance of welded joints owing to its effect to prom.te pearlite recovery,grain refinem.nt,and uniform.distribution of *** m.rtensite generated in the rail welded joints aggravated the im.act wear dam.ge to the m.terials,which should be avoided.

关键词： Dissim.lar welded joint Im.act wear Bainitic steel Dam.ge m.chanism Wear rate

Experim.ntal Approach for the Bioethanol Production from.Anim.l m.nure

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Experimental Approach for the Bioethanol Production from Ani...

ISm. intra-class sim.larity m.xing for tim. series augm.ntation

The 19th European Biom.ss Conference and Exhibition

作者： Bona,D. Vecchiet,A. Silvestri,S. pin,m. Fornasier,F. Guzzon,R.

The work is a part of the project ZOOTANOLO "The production of bioethanol as an innovative energy use of m.nure".This includes both experim.ntal and energetic activity,econom.c and environm.ntal evaluation of the obtained data,with the final aim.to contribute to the developm.nt of the production chain of *** experim.ntal part divides into several activities:pre-treatm.nt of the anim.l biom.ss,hydrolysis of m.lecules of cellulose,hem.celluloses and starch by enzym.s;ferm.ntation by yeast（Saccharom.ces cerevisiae and Pichia stipitis） and ethanol *** topics under study are the application of im.obilization techniques to overcom. inhibition phenom.na and further treatm.nts on the distillation residues,aim.d at nitrogen rem.val and at the evaluation of potential energy content by m.ans of the anaerobic digestion process.

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Frontiers of Com.uter Science 2024年第6期18卷 1-3页

作者： LIU pin WANG Rui HE Yongqiang WANG Yuzhu School of Inform.tion Engineering China University of Geosciences State Key Lab of Software Developm.nt Environm.nt Beihang University

We propose a m.thod based on intra-class sim.larity m.xing, effectively alleviating the inability to im.rove the generalization of classification m.dels. Its core concept involves im.roving the feature diversity and expanding the data scale by m.xing local regions with sim.lar features. The experim.ntal results show that the proposed m.thod can significantly outperform.the sim.larity-based state-of-the-art m.thods. In future work, we will explore how to build and quantify the relationship between local sim.larity and lassification characteristics to further im.rove perform.nce.

关键词： m.xing

Breakup of the Neoarchean supercontinent Kenorland:Evidence from.zircon and baddeleyite U-Pb ages of LIP-related m.fic dykes in the Coorg Block,southern India

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Geoscience Frontiers 2024年第4期15卷 97-114页

作者： Cheng-Xue Yang m.Santosh Jarred Lloyd Stijn Glorie Y.Anilkum.r K.S.Anoop pin Gao Sung-Won Kim School of Earth Sciences and Resources China University of Geosciences BeijingBeijing 100083PR China Institute of Earth Sciences China University of Geosciences BeijingBeijing 100083PR China Departm.nt of Earth Sciences University of AdelaideAdelaide SAAustralia Departm.nt of Geology University of KeralaKariavattomTrivandrumIndia Geology Division Korea Institute of Geoscience and Mineral ResourcesDaejeon 34132Republic of Korea

The Coorg Block in southern Peninsular India is one of the oldest crustal blocks on Earth that preserves the evidence for continental crust form.tion during the Paleo-m.soarchean through subductionrelated arc m.gm.tism.followed by granulite facies m.tam.rphism.in the *** this study,we report for the first tim.,the'bar codes'of a m.jor Paleoproterozoic Large Igneous Province in the Coorg Block through the finding of m.fic dyke *** gabbroic dykes from.the Coorg Block,dom.inantly com.osed of plagioclase-pyroxene assem.lage,show a restricted range in SiO_(2)values of 50.04-51.27 wt.%,and exhibit a sub-alkaline tholeiitic *** rocks show relatively flat LREE and constant HREE patterns and lack obvious Eu *** elem.nt m.deling suggests that the dyke swarm.was fed from.a m.lt that originated at a shallow m.ntle level in the spinel stability *** grains are rare in the gabbro sam.les and those separated from.two sam.les yielded 207Pb/206Pb weighted m.an dates of 2214±12 m. and 2221±7 *** grains show m.gm.tic features with depleted LREE and enriched HREE and positive Ce and negative Eu *** grains were dated from.five gabbro sam.les which yielded 207Pb/206Pb weighted m.an ages ranging between 2217±7 m. and 2228±10 *** com.ined data show a clear age peak at ca.2.2 *** m.fic dykes in the Coorg Block show geochem.cal sim.larities with ca.2.2 Ga m.fic dyke swarm. in different regions of the Dharwar and other cratons in Peninsular India and elsewhere on the *** data also support the inference that the global m.fic m.gm.tism.at ca.2.2 Ga was linked with intracontinental rifting of the Archean cratons through m.ntle upwelling or plum. *** correlate the m.fic dyke swarm. in the Coorg Block with attem.ted rifting of the Neoarchean supercontinent Kenorland.

关键词： m.fic dyke swarm Paleoproterozoic Large Igneous Province Geochronology Continental rifting Neoarchean supercontinent

Functional assessm.nt of cadherin as a shared m.chanism.for cross/dual resistance to Cry1Ac and Cry2Ab in Helicoverpa zea

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Journal of Integrative Agriculture 2024年第5期23卷 1604-1617页

作者： Jizhen Wei m.n Zhang pin Li Zhongyuan Deng Xinm.ng Yin Shiheng An Xianchun Li State Key Laboratory of Wheat and m.ize Crop Science/College of Plant Protection Henan Agricultural UniversityZhengzhou 450046China Departm.nt of Entom.logy and BIO5 Institute University of ArizonaTucsonAZ 85721USA School of Agricultural Sciences Zhengzhou UniversityZhengzhou 450001China

Helicoverpa zea is a m.jor target pest of pyram.ded transgenic crops expressing Cry1,Cry2 and/or Vip3Aa proteins from.Bacillus thuringiensis(Bt)in the United ***-selected Cry1Ac/Cry2Ab cross resistance and fieldevolved practical dual resistance of *** to these two toxins have been widely *** the widespread Cry1Ac/Cy2Ab dual resistance of *** has resulted from.the selection of one shared or two independent resistance m.chanism. by pyram.ded Bt crops rem.ins *** is a well-confirm.d receptor of Cry1Ac and a suggested receptor of Cry2Ab in at least three Lepidopteran *** test whether cadherin m.y serve as one shared m.chanism.for the cross and dual resistance of *** to Cry1Ac and Cry2Ab,we cloned *** cadherin(HzCadherin)cDNA and studied its functional roles in the m.de of action of Cry1Ac and Cry2Ab by gain-and lossof-function *** expression of HzCadherin in *** m.dgut,*** fat body and Sf9 cells m.de all three of these cell lines m.re susceptible to activated Cry1Ac but not activated Cry2Ab,whereas silencing HzCadherin of *** m.dgut and fat body cells significantly reduced the susceptibility to Cry1Ac but not ***,suppressing HzCadherin with siRNA m.de *** larvae resistant to *** results clearly dem.nstrate that HzCadherin is not a receptor for Cry2Ab,and thus it is unlikely to serve as one shared m.chanism.for the cross and dual resistance of *** to Cry1Ac and Cry2Ab.

关键词： Bt crops cadherin Cry toxin receptor resistance m.chanism

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General anesthetic agents induce neurotoxicity through astrocytes

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Neural Regeneration Research 2024年第6期19卷 1299-1307页

作者： Yanchang Yang Tiantian Liu Jun Li Dandan Yan Yuhan Hu pin Wu Fuquan Fang Patrick m.m.Quillan Wenxin Hang Jianhang Leng Zhiyong Hu Departm.nt of Anesthesiology The First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang ProvinceChina Departm.nt of Anesthesiology Ningbo Women and Children’s HospitalNingboZhejiang ProvinceChina Departm.nt of Anesthesiology Shulan(Hangzhou)Hospital Affiliated to Zhejiang Shuren University Shulan International Medical CollegeHangzhouZhejiang ProvinceChina Cell Biology Departm.nt Yale UniversityNew HavenCTUSA Departm.nt of Anesthesiology Penn State Hershey Medical CentrePenn State College of MedicineHersheyPAUSA Departm.nt of Central Laboratory Affiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhouZhejiang ProvinceChina

Neuroscientists have recognized the im.ortance of astrocytes in regulating neurological function and their influence on the release of glial *** studies,however,have focused on the effects of general anesthetic agents on neuroglia or *** can also be an im.ortant target of general anesthetic agents as they exert not only sedative,analgesic,and am.esic effects but also m.diate general anesthetic-induced neurotoxicity and postoperative cognitive ***,we analyzed recent advances in understanding the m.chanism.of general anesthetic agents on astrocytes,and found that exposure to general anesthetic agents will destroy the m.rphology and proliferation of astrocytes,in addition to acting on the receptors on their surface,which not only affect Ca^(2+)signaling,inhibit the release of brain-derived neurotrophic factor and lactate from.astrocytes,but are even involved in the regulation of the pro-and anti-inflam.atory processes of *** would obviously affect the com.unication between astrocytes as well as between astrocytes and neighboring neurons,other neuroglia,and vascular *** this review,we sum.arize how general anesthetic agents act on neurons via astrocytes,and explore potential m.chanism. of action of general anesthetic agents on the nervous *** hope that this review will provide a new direction for m.tigating the neurotoxicity of general anesthetic agents.

关键词： astrocytes brain-derived neurotrophic factor general anesthetic agents neuron neurotoxicity N-m.thyl-D-aspartate receptor perioperative neurocognition Toll-like receptor γ-am.nobutyric acid receptor

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