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Open.Journ.l of Medicin.l Chemistry 2020年第2期10卷 46-55页

作者： v.rma Deepshikha pillai v. n. rajasekharan Departmen. of Chemistry Mewar University Gangrar Chittorgarh Rajasthan India

With the help of the solid phase peptide syn.hesizin. method, we syn.hesized Kalata B2 cyclotide an. the fin.l product was purified by preparativ. HPLC. The sequen.e of Kalata B2 is GLPv.GETCFGGTCn.PGCSCTWPICTRD an. its m/z M + H mass is 2955.53. It had been.first isolated from Olden.an.ia affin.s plan. leav.s extract which belon.s to Rubiaceae family. The syn.hesis of Kalata B2 has been.characterized through UPLC/MS, LC/MS, CD, 1Hn.R, an. IR.

关键词： UPLC LC/MS 1Hn.R IR

Praseodymium metal n.n.rods as a 5-fluorouracil carrier

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Journ.l of Rare Earths 2024年第7期42卷 1328-1336,I0005页

作者： v.rn.tha Man.kan.an.Gov.n.araj Sri v.ralakshmi Ujma Ashapak Tamboli Archan. Sumohan.pillai Aleyamma Alexan.er An.shka Lucas Bose Allben.Akash Israel v.M.v.En.ch Cen.re for n.n.scien.e an. Gen.mics Karunya Institute of Technology and Sciences(Deemed University)Coimbatore641114Tamil NaduIndia Departmen. of Applied Chemistry Karunya Institute of Technology and Sciences(Deemed University)Coimbatore641114Tamil NaduIndia

In.erest in.metal n.n.particles as n.n.scale drug-carryin. v.hicles has been.*** such an.aspect,lan.han.de metal n.n.particles are particularly ***,we report praseodymium n.n.particles as a n.v.l an.ican.er therapeutic tran.portin. *** material was made as a composite with the supramolecular host polymer,poly-β-*** praseodymium n.n.rods were characterized usin. stan.ard an.lytical techn.ques,in.ludin. X-ray diffraction.XRD),X-ray photoelectron.spectroscopy(XPS),an. thermograv.metric an.lysis(TGA).In.addition.they were imaged usin. tran.mission.electron.*** n.n.structures are a lon. rod-shaped material with 2.0±0.1μm in.len.th an. 230±10 n. in.*** material shows a saturation.magn.tization.v.lue abov. 30 emu/g with a coerciv.ty v.lue of 130 *** n.n.carrier is freighted with the drug 5-fluorouracil,an. the en.apsulation.efficien.y is 76.09%.The drug release is con.in.ous from the n.n.carrier(polymer-con.ain.n. praseodymium n.n.particles)an. proceeds for abov. 250 *** in.v.tro cytotoxicities of the blan. n.n.carrier an. the 5-fluorouracil-loaded on. are deduced by testin. them on.MCF-7 an. v.ro(n.n.can.erous)cell *** cytotoxicity on.the can.erous cell lin.s is observ.d,whereas the n.n.can.erous cells are *** IC_(50)v.lues on.the cell lin.s are reported.

关键词： Metal n.n.particles Praseodymium Poly-cyclodextrin Drug deliv.ry An.ican.er activ.ty Rare earths

Laboratory ev.luation.of toxicity of selected in.ecticides again.t egg an. larv.l stages of cotton.pin. bollworm, Pectin.phora gossypiella (Saun.ers) (Lepidoptera: Gelechiidae)

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Journ.l of Cotton.Research 2024年第1期7卷 15-28页

作者： BUSn.OR Abhishek v. WADASKAR R.M. FAn. Babasaheb B. TAMBE v.J. pillai T. MAHULE D.J. n.GRARE v.S. PRASAD Y.G. En.omology Section College of Agriculture(Dr.Panjabrao Deshmukh Krishi Vidyapeeth)Nagpur 440001MaharashtraIndia In.ian.Coun.il of Agricultural Research-Cen.ral In.titute for Cotton.Research Nagpur 441108MaharashtraIndia

Backgroun. The cryptic n.ture of pin. bollworm Pectin.phora gossypiella(Saun.ers)larv.e en.bles its reduced v.l-n.rability to in.ecticidal ***,the dev.lopmen. of resistan.e again.t Bacillus thurin.ien.is(Bt)toxin. posed a serious threat to tran.gen.c cotton.*** n.cessitated determin.n. the critical timin. of spray application. on.the con.rol *** study assessed the in.luen.e of egg age(freshly laid ***-day-old)an. the loca-tion.of larv.e(directly exposed to the in.ecticide residues on.the boll rin. *** in.ide the bolls)on.in.ecticide con.rol *** The results rev.aled a sign.fican. decrease in.the ov.cidal activ.ty of tested in.ecticides with an.in.rease in.the age of eggs from on. day old to three days old(paired t-test,Pv.e directly exposed to the in.ec-ticide residues on.the boll rin. were more susceptible(>80%mortality)than.the larv.e exposed after they had bur-rowed in.ide the bolls(n.ibitory effects of tested in.ecticides on.dev.lopmen.al biology were more pron.un.ed in.the experimen. on.pre-larv.l release in.ecticide treatmen. compared with in.ecticide treatmen. giv.n.post-larv.l release an. en.ry in.ide the *** Egg age in.luen.es the in.ecticide susceptibility,as does the larv.l location.directly exposed v. bur-rowed in.ide the *** eggs an. the larv.e that had burrowed in.ide the green.bolls of cotton.were relativ.ly less susceptible to the in.ecticide *** toxic effects of in.ecticides on.egg an. larv.l stages were primar-ily *** fin.in.s are sign.fican. for dev.sin. a comprehen.iv. strategy for pin. bollworm man.gemen. on.a sustain.ble basis.

关键词： Bioefficacy Cotton In.ecticides Pin. bollworm Pectin.phora gossypiella Timin.s of spray

Un.uperv.sed in.rusion.detection.system for in.v.hicle commun.cation.n.tworks

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Journ.l of Safety Scien.e an. Resilien.e 2024年第2期5卷 119-129页

作者： Kabilan.n.v.n.yakumar Rav. v.Sowmya Cen.er for Computation.l En.in.erin. an. n.tworkin.(CEn. Amrita School of Artificial InteligenceAmrita Vishwa VidyapeethamCoimbatoreIndia Cen.er for Artificial In.lligen.e Prince Mohammad Bin Fahd UniversityKhobarSaudi Arabia

In.v.hicle commun.cation.has been.optimized day to day to keep updated of the *** area n.twork(CAn.is used as a stan.ard commun.cation.method because of its efficien. an. reliable ***,CAn.is pron. to sev.ral n.twork lev.l attacks because of its lack in.security *** methods hav. been.in.roduced to in.orporate this in.*** proposed an.un.uperv.sed method of in.rusion.detection.for in.v.hicle commun.cation.n.tworks by combin.n. the optimal feature extractin. ability of autoen.oders an. more precise clusterin. usin. fuzzy C-mean.(FCM).The proposed method is light weight an. requires less computation.*** performed an.exten.iv. experimen. an. achiev.d an.accuracy of 75.51%with the ML35o in.v.hicle in.rusion.*** experimen.al result,the proposed method also works better for other in.rusion.detection.problems like wireless in.rusion.detection.datasets such as Wn.-DS with accuracy of 84.05%an. n.twork in.rusion.detection.datasets such as KDDCup with accuracy 60.63%,Un.W_n.15 with accuracy 73.62%an. In.ormation.Security Cen.er of Excellen.e(Iscx)with accuracy 74.83%.Ov.rall,the proposed method outperforms the existin. methods an. av.ids labeled datasets when.train.n. an.in.v.hicle in.rusion.detection.*** results of the experimen. of our proposed method performed on.v.rious in.ru-sion.detection.datasets in.icate that the proposed approach is gen.ralized an. robust in.detectin. in.rusion. an. can.be effectiv.ly deployed in.real time to mon.tor CAn.traffic in.v.hicles an. proactiv.ly alert durin. attacks.

关键词： Con.rolarea n.twork In.rusion.etection Un.uperv.sed learn.n. Autoen.oders Fuzzy C-mean.

Thermo-an. pH-sen.itiv. Polymer with Pen.an. Spacer-lin.ed Imidazole Cycles

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Chin.se Journ.l of Polymer Scien.e 2024年第4期42卷 437-445页

作者： n.talya v.Zakharov. Stan.slav.n.Zelin.kiy Mariya S.Strelov. Elen. n.Dan.lov.sev. v.dim v.An.en.ov In.titute of Macromolecular Compoun.s of the Russian.Academy of Scien.es Saint Petersburg199004Russia Limn.logical In.titute of Siberian.Bran.h of the Russian.Academy of Scien.es Irkutsk664033Russia

By the reaction.of poly(acryloyl chloride) with n.(3-amin.propyl)imidazole, poly(n.(3-(1H-imidazol-1-yl)propyl)acrylamide) was syn.hesized. The n.w polymer con.ain. an.imidazole rin. remov.d from the main.chain.by a spacer of fiv. bon.s. The structure an. purity, molecular weight, hydrodyn.mic an. thermosen.itiv. properties of the obtain.d sample were studied by1H-an.13C-n.R, FTIR spectroscopy, acid-base titration. light scatterin., turbidimetry an. v.scometry. The observ.d ability of the imidazole-con.ain.n. polymer to form an. destroy associates in.water-salt solution. at pH 6.6-7.4 an. temperatures of 29-48℃ in.icates that these are promisin. can.idates for design.n. complex biomedical systems. The n.w polymer is able to form complexes with oligo-Dn. more activ.ly than.poly(1-v.n.limidazole), which is of in.erest for gen. deliv.ry application.. The polymer cross-lin.ed with epichlorohydrin.giv.s micro-relief coatin.s on.the plastic surface, an. the modified surface is able to attach n.gativ.ly charged objects. This thermo-an. pH-sen.itiv. polymer modification.can.be applied to create fin.ly con.rolled surfaces for cell culturin..

关键词： Imidazole-con.ain.n. polymer Thermolability pH-sen.itiv.ty The modified surface Dn. immobilization

RBC aggregation.deformation.an. adhesion.to en.othelium:Role of n.tric oxide deriv.d from L-Argin.n. an. sodium n.troprusside

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Journ.l of In.ov.tiv. Optical Health Scien.es 2024年第5期17卷 53-65页

作者： M.K.Maksimov.P.B.Ermolin.kiy O.n.Scheglov.tov. n.n.Sklyan.in. A.v.Murav.ov.A.E.Lugov.sov.A.v.Priezzhev Faculty of Physics M.V.Lomonosov Moscow State University bld.1subbuilding.2Leninskie goryMoscow 11991Russia n.F.Gamaleya n.tion.l Research Cen.er for Epidemiology an. Microbiology 18 Gamaleya StreetMoscow 123098Russia K.D.Ushin.ky Yaroslav. State Pedagogical Un.v.rsity 108/1 Respublikanskaya StreetYaroslavl 150000Russia

Red blood cells(RBCs)are the most abun.an. human.blood *** aggregation.an. deformation.stron.ly determin. blood v.scosity which impacts hemorheology an. *** turn.RBC properties depen. on.di®eren. en.ogen.us an. exogen.us *** such factor is n.tric oxide(n.),which is main.y produced by en.othelial cells(EC)from L-argin.n. amin. acid in.the circulatory *** the mechan.sms of the RBC-en.othelium in.erplay are n.t clear up to date an. con.iderin. its possible clin.cal importan.e,the aims of this study are to in.0}stigate in.v.tro:(1)The e®ect of L-argin.n. in.uced n. on.RBC aggregation.an. adhesion.to en.othelium;(2)the n. e®ect on.RBC aggregation.an. deformation.in.uced by L-argin.n. an. sodium n.troprusside without the presen.e of en.othelium in.the *** RBC aggregation.an. adhesion.to a mon.layer of EC were studied usin. optical tweezers(OT).The RBC deformability an. aggregation.without en.othelium in.the samples were studied usin. the°ow chamber method an. Myren.e *** con.rmed that n. in.reases deformability an. decreases aggregation.of *** showed that the soluble guan.late cyclase pathway appears to be the on.y n. sign.lin. pathway *** the samples with the en.othelium,the\bell-shaped"depen.en.e of RBC aggregation.force on.L-argin.n. con.en.ration.was observ.d,which improv.s our kn.wledge about the process of n. production.by ***,data related to L-argin.n. accumulation.by en.othelium were obtain.d:n.cessity of the presen.e of extracellular L-argin.n. stated by other authors was put un.er *** our study,n. decreased the RBC-en.othelium adhesion.howev.r,the ten.en.y appeared to be weak an. was n.t con.rmed in.an.ther set of *** our kn.wledge,this is the¯rst attempt to measure the forces of RBC adhesion.to en.othelium mon.layer with OT.

关键词： Red blood cells aggregation L-argin.n. en.othelium optical tweezers Myren.e flow chamber

n.n.in.ar-Optical An.logies in.n.clear-Like Soliton.Reaction.:Selection.Rules,n.n.in.ar Tun.elin. an. Sub-Barrier Fusion.Fission

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Chin.se Physics Letters 2024年第8期41卷 1-7页

作者： T.L.Belyaev. v.n.Serkin Un.v.rsidad Auton.ma del Estado de Mexico Av.Instituto Literario 100C.P.50000TolucaMexico Ben.merita Un.v.rsidad Auton.ma de Puebla Av.4 Sur 104C.P.72001PueblaMexico

The main.goal of our study is to rev.al un.xpected but in.riguin. an.logies arisin. between.optical soliton. an. n.clear physics,which still remain.hidden.from *** con.ider the main.corn.rston.s of the con.ept of n.n.in.ar optics of n.clear reaction. an. the well-dressed repulsiv.-core *** the base of this model,we rev.al the most in.riguin. properties of the n.n.in.ar tun.elin. of n.cleus-like soliton. an. the soliton.selfin.uced sub-barrier tran.paren.y *** describe n.v.l in.erestin. an. stimulatin. an.logies between.the in.eraction.of n.cleus-like soliton. on.the repulsiv. barrier an. n.clear sub-barrier *** main.fin.in. of this study con.ern. the con.erv.tion.of total n.mber of n.cleon.(or the baryon.n.mber)in.n.clear-like soliton.*** show that in.lastic in.eraction. amon. well-dressed repulsiv.-core soliton. arise on.y when.a“cloud”of“dressin.”spectral side-ban.s appears in.the frequen.y spectra of the *** property of n.cleus-like soliton. is directly related to the n.clear den.ity distribution.described by the dimen.ion.ess small shape-squaren.ss *** the Fourier spectra of n.cleus-like soliton. are similar to the n.clear form *** show that the n.clear-like reaction. between.well-dressed soliton. are realized by“exchan.e”between.particle-like”side ban.s in.their spectra.

关键词： soliton. soliton n.n.in.ar

Morphology of crater an. caldera lakes in.the Far Eastern.region.of Russia an. the features of their dev.lopmen.

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Journ.l of Moun.ain.Scien.e 2024年第4期21卷 1246-1258页

作者： Dmitrii n.KOZLOv.Ekaterin. v.LEBEDEv. In.titute of Marin. Geology an. Geophysics Far Eastern Branch of the Russian Academy of SciencesYuzhno-Sakhalinsk 693022Russia In.titute of Geography Russian Academy of SciencesMoscow 119017Russia

v.lcan.c lakes in.the Kuril-Kamchatka region.are difficult to access,an. for this reason.they remain.poorly studied,with on.y scattered an. brief data *** authors hav. con.ucted a study of 10 lake basin. usin. modern.digital echolocation.surv.y techn.ques an. hav. also compiled an. summarized published data for 15 lakes in.the region.calculatin. their main.morphometric *** has been.established that man. caldera lake basin. are modified by youn. explosiv. fun.els,extrusiv. or effusiv. domes,an. exhibit traces of hydrothermal *** lakes of the same gen.tic type in.the Kuril-Kamchatka region.are similar in.depth an. depression.forms,the group of caldera lakes shows less homogen.ity across all morphometric *** was foun. that the absolute heights of the reserv.irs on.Kamchatka Pen.n.ula are gen.rally greater than.those on.the Kuril Islan.s,as is often.the case with the size of their *** v.lcan.c lakes un.er study can.rapidly chan.e their v.lume an. shape un.er the in.luen.e of en.ogen.us *** the first time for this region.on.the base of repeated observ.tion.,un.erwater extrusiv. dome rate growth an. the approximate rates of 2 lake lev.l chan.es were *** observ.tion. of lakes in.the Ksudach calderas(Kamchatka)an. on.Simushir Islan. in.icate approximate rates of lev.l chan.es:a decrease ran.in. within.0.5-0.6 m per year(ov.r a 27-year observ.tion.in.erv.l)an. an.in.rease reachin. up to 0.26 m per year(ov.r a 48-year in.erv.l).The growth rate of the un.erwater extrusiv. dome in.Lake Shtyubel has av.raged 1-1.6 m per year ov.r the past 25 *** an.lysis has facilitated the first gen.ralization.regardin. the morphology an. dev.lopmen.al features of crater an. caldera lakes in.the Kuril-Kamchatka region.of Russia,represen.in. an.importan. step in.their *** results obtain.d will prov.de a solid foun.ation.for subsequen. research in.this region.an. may be of in.erest to researchers studyin.

关键词： v.lcan.c lakes Echolocation.surv.y v.lcan.sm Gashydrotherms Kamchatka Kuril Islan.s

Con.ormally symmetric wormhole solution. supported by n.n.commutativ. geometry in.f(Q,T)grav.ty

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Commun.cation. in.Theoretical Physics 2024年第2期76卷 111-124页

作者： Chaitra Chooda Chalav.di v.v.n.atesha n.S Kav.a S v.Div.a Rashmi Departmen. of P.G.Studies an. Research in.Mathematics Kuvempu UniversityShankaraghattaShivamogga 577451KarnatakaIndia Departmen. of Mathematics Vidyavardhaka College of EngineeringMysuru—570002India

This paper in.0}stigates wormhole solution. within.the framework of exten.ed symmetric teleparallel grav.ty,in.orporatin. n.n.commutativ. geometry,an. con.ormal *** achiev. this,we examin. the lin.ar wormhole model with an.sotropic fluid un.er Gaussian.an. Loren.zian.*** primary objectiv. is to deriv. wormhole solution. while con.iderin. the in.luen.e of the shape fun.tion.on.model parameters un.er Gaussian.an. Loren.zian.*** resultin. shape fun.tion.satisfies all the n.cessary con.ition. for a trav.rsable ***,we an.lyze the characteristics of the en.rgy con.ition. an. prov.de a detailed graphical discussion.of the matter con.en.s v.a en.rgy ***,we explore the effect of an.sotropy un.er Gaussian.an. Loren.zian.***,we presen. our con.lusion. based on.the obtain.d results.

关键词： trav.rsable wormhole f(Q T)grav.ty en.rgy con.ition. n.n.commutativ. geometry con.ormal motion

Ion.heat tran.port in.electron.cyclotron.reson.n.e heated L-mode plasma on.the T-10 tokamak

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Plasma Scien.e an. Techn.logy 2024年第4期26卷 52-60页

作者： v.A.KRUPIn.M.R.n.RGALIEv.A.R.n.METS I.A.ZEMTSOv.S.D.SUn.SOv.T.B.MYALTOn.D.S.SERGEEv.n.A.SOLOv.v.D.v.SARYCHEv.D.v.RYJAKOv.S.n.TUGARIn.v.n.n.n.UMEn.O n.tion.l Research Cen.re“Kurchatov.In.titute” Moscow 123182Russia Bauman.Moscow State Techn.cal Un.v.rsity Moscow 105005Russia In.titution.Project Cen.er ITER” Moscow 123098Russia JSC“SOLAR” Minsk 220034Belarus

An.malous ion.heat tran.port is an.lyzed in.the T-10 tokamak plasma heated with electron.cyclotron.reson.n.e heatin.(ECRH) in.secon.-harmon.c extra-ordin.ry mode. Predictiv. modelin. with empirical scalin. for Ohmical heat con.uctiv.ty shows that in.ECRH plasmas the calculated ion.temperature could be ov.restimated, so an.in.rease of an.malous ion.heat tran.port is required. To study this effect two scan. are presen.ed: ov.r the EC reson.n.e position.an. ov.r the ECRH power. The EC reson.n.e position.v.ries from the high-field side to the low-field side by v.riation.of the toroidal magn.tic field. The scan.ov.r the heatin. power is presen.ed with on.axis an. mixed ECRH regimes. Discharges with high an.malous ion.heat tran.port are obtain.d in.all con.idered regimes. In.these discharges the power balan.e ion.heat con.uctiv.ty exceeds the n.oclassical lev.l by up to 10 times. The high ion.heat tran.port regimes are distin.uished by three parameters: the ratio Te/Ti, the n.rmalized electron.den.ity gradien. R/■, an. the ion.ion.collision.lity νii~*. The combin.tion.of high Te/Ti, high νii~*, an. R/■=6-10 results in.v.lues of n.rmalized an.malous ion.heat fluxes up to 10 times higher than.in.the low tran.port scen.rio.

关键词： tokamak L-mode electron.cyclotron.reson.n.e heatin. ion.heat tran.port